1.Serum IgE Levels and Incidence of Atopic Disease according to Infant Diet.
Jeong Wan SEO ; Seung Joo LEE ; Keun LEE
Journal of the Korean Pediatric Society 1985;28(8):751-755
No abstract available.
Diet*
;
Humans
;
Immunoglobulin E*
;
Incidence*
;
Infant*
2.Postnatal Changes of Serum Creatinine Levels in Neonates.
Jeong Wan SEO ; Seung Joo LEE ; Keun LEE
Journal of the Korean Pediatric Society 1986;29(9):20-25
No abstract available.
Creatinine*
;
Humans
;
Infant, Newborn*
3.Two Cases of Pseudohypoaldosteronism Type I.
Ji Eun LEE ; Jung Wan SEO ; Seung Joo LEE
Journal of the Korean Pediatric Society 1994;37(1):122-128
Pseudohypoaldosteronism type 1 is a genetic renal tubular disease of salt wasting, presenting in young infants. Tubular unresponsiveness to elevated endogenous and exogenous aldosterone is the suggested pathogenetic mechanism. Oral sodium chloride supplementation relieve the clinical symptoms and electrolyte distrubances. We experienced 2 cases of PHA type 1 in 38-day and 45-day old male infants who were presented with failure to thrive, vomiting and/or dehydration. Laboratory data showed hyponatremia, hyperkalemia, hypochloremia and metabolic acidosis. Renal and adrenal functions were normal. Plasma renin activity and plasma aldosterone concentration were markedly elevated. Under the diagnosis of pseudohypoaldosteronism type 1, oral supplementation of NaCl and/or kayexalate improved the clinical states of the patients.
Acidosis
;
Aldosterone
;
Dehydration
;
Diagnosis
;
Failure to Thrive
;
Humans
;
Hyperkalemia
;
Hyponatremia
;
Infant
;
Male
;
Plasma
;
Pseudohypoaldosteronism*
;
Renin
;
Sodium Chloride
;
Vomiting
4.A Cases of Familial Spastic Paraplegia (FSP).
Jung Sang HA ; Won Hee CHOI ; Choong Seo PARK ; Yung Joo BYUN ; Bo Wan SEO
Journal of the Korean Neurological Association 1985;3(2):291-297
We present a family of FSP with review of literatures. Seeligmuller (1876) and Strumpell (1880) were the first to describe familial case of spastic paraplegia characterized by progressive weakness and spasticity of the lower limbs with little or no involvement of the upper extremities. This syndrome is heterogenous in inheritance, age of onset, severity and associated signs. A pure type without complications has been named "Strumpell's FSP". We have recently experienced a case of 17 years old male who had bilateral weakness and stiffness of lower extremities, and gait disturbance with family history. Differential diagnosis, particularly with familial amyotrophic lateral sclerosis, is discussed.
Adolescent
;
Age of Onset
;
Amyotrophic Lateral Sclerosis
;
Diagnosis, Differential
;
Gait
;
Humans
;
Lower Extremity
;
Male
;
Muscle Spasticity*
;
Paraplegia*
;
Upper Extremity
;
Wills
5.Renal Toxicity of High-dose Intravenous Immunoglobulin in Children with Kawasaki Disease and Idiopathic Thrombocytopenic Purpura.
Jung Wan SEO ; Sung Joo LEE ; Hye Soon KIM ; Ji Ah JUNG
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):133-137
We describe a case of fine needle aspiration cytology of metastatic nasopharyngeal carcinoma in the lymph node of the neck presenting a predominantly spindle cell pattern. A 36 year-old male patient complained of dysesthesia on the right face and a palpable neck mass. Fine needle aspiration was done on the neck mass. Tumor cells were present in syncytial groups or singly with mainly spindle shaped nuclei, vesicular chromatin, thin and regular nuclear membrane, occasional prominent nucleoli and a few foci of cellular cohesiveness. The cytoplasm was scant and pale with ill-defined borders. Mature lymphocytes were present in the background of aspirates and within the tumor cell clusters. Histologically, the tumor of nasopharynx showed several areas of spindle cell pattern. Because the tumor cells showed a predominantly spindle shape with vesicular nuclear chromatin, the differential diagnosis of spindle cell sarcoma or granuloma of epithelioid cells were considered, but the characteristic morphology of the nuclei with vesicular chromatin and prominent nucleoli, and cellular cohesiveness were important in making the diagnosis of nasopharyngeal carcinoma. The possibility of metastatic carcinoma should always be considered in fine needle aspiration cytology of the lymph node in the neck because the incidence of metastatic carcinoma, particularly of the nasopharyngeal carcinoma in the lymph nodes of the neck is relatively high.
Child
;
Male
;
Female
;
Humans
;
Diagnosis, Differential
;
Incidence
;
Neoplasm Metastasis
6.Serum Zinc Concentration in Children with Acute Gasrtoenteritis.
Hyun Joo LEE ; Hye Won YOM ; Jeong Wan SEO
Korean Journal of Pediatric Gastroenterology and Nutrition 2006;9(1):14-22
PURPOSE: To identify factors that influence serum zinc concentrations in children with acute gastroenteritis. METHODS: Thirty-two children under 5 years of age (15 boys and 17 girls) were selected randomly among those who visited to an pediatric emergency room of Ehwa Womans University Mokdong Hospital with acute gastroenteritis from May to August 2005. This study estimated the association between serum zinc concentrations and clinical, biochemical variables in patients with acute gastroenteritis. RESULTS: Serum zinc concentration was lower in febrile patients than afebrile patients with acute gastroenteritis (67.0+/-25.3 vs 85.5+/-14.2, p<0.05). It also was lower in patients with positive C-reactive protein (CRP) than those with negative CRP (63.9+/-25.4 vs 86.7+/-13.8, p<0.05). Serum zinc concentration was negatively correlated (r=-0.494, p<0.05) with CRP concentration, whereas positively correlated with hematocrit (r=0.370, p<0.05), total protein (r=0.474, p<0.05), and albumin (r=0.636, p<0.05). Twelve patients (37.5%) showed very low serum zinc concentration (<70 microgram/dL) without clinical symptoms of deficiency or growth retardation. Frequency of febrile illness or positive CRP is significantly greater in group with zinc <70 microgram/dL than the group with zinc > or =70 microgram/dL (91.7% vs 55%, p<0.05; 91.7% vs 40%, p<0.05, respectively). CONCLUSION: In patients with acute gastroenteritis, serum zinc concentration was influenced by various factors such as fever, CRP, and biochemical factors. For evaluating zinc status in the body. factors.
C-Reactive Protein
;
Child*
;
Emergency Service, Hospital
;
Female
;
Fever
;
Gastroenteritis
;
Hematocrit
;
Humans
;
Zinc*
7.Risk Factors of Primary Nocturnal Enuresis.
Soo Jin LEE ; Jin Won YOOK ; Yoo Eun SUN ; Jung Wan SEO ; Sung Joo LEE
Journal of the Korean Society of Pediatric Nephrology 2000;4(1):69-76
Urinary cytology has become an essential element in the diagnosis and management of transitional cell carcinoma(TCC) of the urinary tract. It has the advantage of being noninvasive, inexpensive, and easily accessible. Besides that it can even detect malignancy when unsuspected at cystoscopy. We report a retrospective review of urine cytology in the diagnosis of 83 TCC cases that underwent 295 cytologic evaluation. All patients had biopsy-proven TCC of the bladder, ureter and renal pelvis. The overall inci- dence of the positive cytology cases was 66.2%. To define the cytologic features of tumor cells, we tried to use three cytologic gradings such as "grade 1", "grade 2", and "grade 3" according to the cytologic degree of anaplastic neoplastic cells. These cytologic gades of TCC were relatively well correlated with the histologic grade and tumor invasiveness. This result suggests that the recognition of characteristic cellular features of TCC can suspect the histologic grade and tumor stage. The false negative TCC cases were 78.9%. They showed severe inflammatory or bloody background and a few neoplastic cells. Therefore, a cautious approach for accurate interpretation, personal experience, and proper fixation and processing could expand the role of urinary cytology.
Cystoscopy
;
Diagnosis
;
Humans
;
Kidney Pelvis
;
Nocturnal Enuresis*
;
Retrospective Studies
;
Risk Factors*
;
Thyroid Gland
;
Ureter
;
Urinary Bladder
;
Urinary Tract
8.A Clinical Study of the Surgical Treatment of the Thoraco-Lumbar Spinal Injuries
Kwang Yoon SEO ; Byung Jik KIM ; Young Koo LEE ; Yoon Pyo HONG ; Joo Wan PARK
The Journal of the Korean Orthopaedic Association 1982;17(6):1101-1112
Among 334 thoracolumbar spinal injury patients who were admitted to this hospital from June 1972 to June, 1982, 66 patients with fracture and fracture dislocation of thoraco-lumbar spine which were defined as unstable clinically and radiologically were treated with surgical measures. The ratio between male and female was 7.3:1, the majority was found in third and fourth decade (46 cases, 69%), and the most common cause of injury was falling from a height (38 cases, 58%). The most common site of the injury was lumbar spine (29 cases, 44%) and the most common mechanism of injury was flexion-rotation (29 cases, 44%). Our surgical measures were Harrington rod instrumentation with either anterior or posterior fusion (25 cases, 38%), posterior wiring and fusion (14 cases, 21%), anterior decompression and anterior fusion (14 cases, 21%), posterior fusion (4 cases, 6%), anterior fusion and posterior fusion (3 cases, 5%) and etc. The average correction of displacement was 65% and the average correction of kyphotic deformity was 50%. The most remarkable correction was found at the cases of Harrington rod instrumentation (71%, 74%). Neurological deficit had already developed in 43 cases(65%) prior to operation, and the recovery was observed in 18 cases(42%). Most excellent recovery of neural deficit was found also at the cases of Harrington rod instrumentation (11 cases, 52%). We have analysed the results of these treatment and obtained following conclusions. 1. For the unstable fracture and fracture-dislocation of thoraco-lumbar spine with or without neural involvement, immediate surgical treatments were valuable to expect restoration of anatomical reduction and promotion of every possible recovery of neural function with spinal stability and fewest complication. 2. Fixation with Harrington rod instrumentation appears to provide better reduction and stability with neural improvement than other methods, and therefore early undertaking of rehabilitation activities is possible. 3. For the patients who are seriously compromised or require anterior decompression, immediate posterior reduction and fixation with Harrington rod instrumentation followed anterior decompression and anterior fusion of the involved segments at the eariest feasible time, we feel, is the treatment of choice.
Accidental Falls
;
Clinical Study
;
Congenital Abnormalities
;
Decompression
;
Dislocations
;
Female
;
Humans
;
Male
;
Mortuary Practice
;
Rehabilitation
;
Spinal Injuries
;
Spine
9.Fracture and Dislocation of Cervical Spine
Kwang Yoon SEO ; Byung Jik KIM ; Young Koo LEE ; Yoon Pyo HONG ; Joo Wan PARK
The Journal of the Korean Orthopaedic Association 1982;17(6):1089-1100
There was increasing tendency to stabilize unstable cervical spine injuries surgically with the benefit of good stability of the spine, easy nursing care, early mobilization and therefore early rehabilitation. A clinical study was performed on 47 patients with fractures and dislocations of the cervical spine treated at the department of orthopedic surgery, Inje Medical College, Paik Hospital from Jan. 1975 to Dec. 1981. Following is the summery of the our findings. 1. The prevalent age distribution was between 3rd and 6th decade and the ratio between males and females was 10:1. The most common cause of injuries was automobile accident (70%). 2. The most common site of the injuries was C5-6 (34%) and the most frequent mechanism of injury was flexion-rotation type (47%). 3. In overall patients, neurologic damage was found at first examination in 73% and among these, complete paralysis below the injured level in 26%, incomplete paralysis in 11% and nerve root injury in 35%. 4. Among 47 patients, conervative treatment was performed on 9 patients, anterior spinal fusion on 8 patients, anterior spinal fusion with Halo application on 4 patients, posterior wiring with posterior spinal fusion on 16 patients and posterior wiring with anterior spinal fusion on 8 patients. 5. In the several methods of treatment, the posterior wiring with anterior spinal fusion revealed the best results, the correction rate of displacement was 92%, the correction rate of angular deformity 98% and neural recovery rate 72%. 6. The posterior wiring with posterior spinal fusion revealed good results in correction of displacement and angular deformity but required rigid external support for a long time. The anterior spinal fusion revealed poor results in correction of displacement(67%) and angular deformity(38%) and required rigid external support for a long time and had increasing tendency of kyphotic angle after operation. 7. In the treatment of unstable cervical spine injury, we thoughy that early posterior reduction with posterior wiring and followed anterior spinal fusion was ideal for accurate reduction, rigid stability and early mobilization with simple external support.
Age Distribution
;
Automobiles
;
Clinical Study
;
Congenital Abnormalities
;
Dislocations
;
Early Ambulation
;
Female
;
Humans
;
Male
;
Nursing Care
;
Orthopedics
;
Paralysis
;
Rehabilitation
;
Spinal Fusion
;
Spine
10.A Giant Cell Tumor of the Lumbar Vertebra: One Case Report
Chil Soo KWON ; Kwang Yoon SEO ; Young Geun RHO ; Joo Wan PARK
The Journal of the Korean Orthopaedic Association 1981;16(3):722-725
Giant cell tumor of the spine is a rare and potentially malignant condition which presents rather difficult clinical problems in treatment because of their localization and unpredictable clinical course. Authors experienced a case of giant cell tumor involving third lumbar vertebra which was successfully treated by ea bloc resection and anterior interbody fusion of the adjoining vertebrae with iliac bone graft. At eighteen months follow up, there is no evidence of recurrence and solid union of the bone graft was noted.
Follow-Up Studies
;
Giant Cell Tumors
;
Giant Cells
;
Recurrence
;
Spine
;
Transplants