PURPOSE: This study was to evaluate the clinical usefulness of 99mTc-MDP bone scintigraphy for assessing vascular ingrowth into the ocular implants after enucleation or evisceration. MATERIALS AND METHODS: Twenty-four patients (M:F=7:17, mean age: 36 years), who buried a coralline hydroxyapatite after uncomplicated enucleation or evisceration surgery were studied. Dynamic and static scintigraphy on the orbit fossa were obtained after injection of 740 MBq 99mTc-MDP to evaluate the status of vascularization. The study was performed from the 3 to 33 weeks after surgery. According to the visual analysis, activity greater than nasal bridge was graded as 4, equal to the nasal bridge as 3, less than nasal bridge but greater than normal orbit as 2, greater than normal orbit but less than grade 2 as 1. Uptake ratio was also calculated by measuring the implants activity (H) and contralateral orbit activity (N). Grading score and uptake ratio were compared with clinical outcome of vascularization. Additionally, we also analyzed the vascularization status as time lapse between primary surgery and scintigraphic study and surgical methods. RESULTS: Twenty-one patients who had bone scintigraphy at 11 weeks after surgery showed increased uptake above grade 2 and greater H/N ratio than 1.56. Of these, 19 patients who had drilling surgery for permanent peg application showed adequate bleeding during the procedure. The activity grade and uptake ratio were inversely correlated with vascular ingrowth. Higher than grade 2 or greater than 1.56 in H/N ratio seemed to be an indicator for better prognosis. Accomplishment of vascularization was not affected by the surgical way such as enucleation or evisceration. CONCLUSION: 99mTc-MDP bone scintigraphy can be a useful method to evaluate the vascularized status of implants. Adequate time for 99mTc-MDP bone scintigraphy may be 11-20 weeks after enucleation or evisceration.
Durapatite* ; Hemorrhage ; Humans ; Orbit ; Prognosis ; Radionuclide Imaging* ; Technetium Tc 99m Medronate*

We experienced 12 cases of 8 patients Duputren's contracture, which is a rare disease entity and characterized by proliferative fibroplasia of the subcutaneous palmar aponeurosis and contracture of the palmar fascia and result in the deformity of the hand and fingers. Among 12 cases, we operated 11 cases and the result was excellent in 2 cases and good in 6 cases, and there were no evidence of recurrence over the follow-up period, average 4.1 years.
Congenital Abnormalities ; Contracture ; Dupuytren Contracture ; Fascia ; Fingers ; Follow-Up Studies ; Hand ; Humans ; Rare Diseases ; Recurrence

No abstract available.
Nucleopolyhedrovirus* ; Sequence Analysis*

PURPOSE: This paper evaluate and classified the risk factors that could possibly cause ischemic stroke in children, and investigate whether TOAST classification could be applied to the ischemic stroke in children. METHODS: From March 1995 to February 2002, we retrospectively reviewed the medical record of 87 patients under the age 16 who had been registered to the Ajou Stroke Registry. We evaluated the risk factors of ischemic stroke according to the Ajou Stroke Registry Protocol, and classified the risk factors into 6 main subgroups. In addition, the risk factors were investigated according to the age distribution. TOAST classification had been applied to children with ischemic stroke. RESULTS: There was 64 ischemic stroke(73.6%) and 23 hemorrhagic stroke(26.4%) among the 87 patients. In children with ischemic stroke, there was three major peak age; 13 patients younger than 1 year old(15.3%), 26 patients in age 5 to 8 years old(40.6 %), 22 patients in 9 to 12 years old(34.3%). Vasculopathy(48.6%) was the most common risk factor of the ischemic stroke in this study. Other important risk factors in order of frequency were hypertensive encephalopathy(12.5%), infectious disease(7.8%), metabolic disease(7.8%), and hematologic disease(6.2%). Moyamoya disease was the most common cause of ischemic stroke due to vasculopathy. If we analyze the risk factors according to the age at the presentation of ischemic stroke, 90% of the ischemic stroke due to vasculopathy had been developed after 5 years of age. However, ischemic stroke due to infectious disease had been developed less than 4 years of age. Major stroke was the most common subtype of the ischemic stroke in children, but TIA had been found in 80% of the patients with ischemic stroke due to moyamoya disease. TOAST classification determined the subtype of the ischemic stroke only in 2 children. Risk factors of ischemic stroke in the remained 62 patients were extremely variable, and could not be applicable to the TOAST classification. CONCLUSION: Risk factor of ischemic stroke were found in the 90% of patients. Although risk factors of ischemic stroke were extremely variable in children, cerebral vasculopathy including moyamoya disease was the most common. However, inherited metabolic disorder, coagulopathy, and hypertensive encephalopathy were also relatively common risk factors of ischemic stroke especially in children older than 5 years old. Therefore, we must extensively evaluate all the possible risk factors of ischemic stroke in children. TOAST classification could not be applicable in children because the risk factors of ischemic stroke were extremely variable.
Age Distribution ; Child* ; Child, Preschool ; Classification ; Communicable Diseases ; Humans ; Hypertensive Encephalopathy ; Medical Records ; Moyamoya Disease ; Retrospective Studies ; Risk Factors* ; Stroke*

SUMMARY OF LITERATURE REVIEW: Many authors haute described the association between lumbar disc degeneration and segmental instability but it has not been delineated in detail. OBJECTIVES: To compare the MRI assessment of disc degeneration with the conventional plain X-ray evaluation of the intervertebral disc, in order to study lumbar segmental instability. MATERIALS AND METHODS: In 75 patients with low back pain and/or sciatica, we analyzed disc space height, angular displacement, and horizontal displacement on plain radiographs of the lumbar spine. These parameters were compared with the grade of disc degeneration as evaluated by magnetic resonance Imaging. STUDY DESIGN: We analyzed the association between grade of disc degeneration as evaluated by magnetic resonance imaging assessment and segmental instability as evaluated by plain radiographs of the lumbar spine. RESULTS: Disc space height was decreased In proportion to the grade of disc degeneration. Angular displacement was increased according to the grade of disc degeneration, but significantly less with severe degeneration, accompanied by a tendency to stabilization of the motion segment. Horizontal displacement was not correlated with the grade of disc degeneration CONCLUSIONS: The incidence of lumbar segmental instability increased in proportion to the grade of disc degeneration but significantly decreased with severe disc degeneration.
Humans ; Incidence ; Intervertebral Disc ; Intervertebral Disc Degeneration* ; Low Back Pain ; Magnetic Resonance Imaging ; Sciatica ; Spine

BACKGROUND: Genital herpes is a sexually transmitted disease, which affects millions of people worldwide, and is caused by the herpes simplex virus (HSV). Recent data has shown that in a large proportion of genital herpes, there has been a shift from HSV type 2 (HSV-2) to to HSV type 1 (HS V-1) being the main cause. OBJECTIVE: Our objective was to study the types of virus and clinical patterns of patients with genital herpes in Korea METHODS: We investigated the clinical patterns and virus types of 13 patients with genital herpes using indirect immunofluorescence (IIF) after viral culture, and/or nested-multiplex polymerase chain reaction (NM-PCR). RESULTS: Of the 13 patients, HSV-1 was isolated in 2 patients (15.4%), HSV-2 in 7 patients (53.8%), and mixed infection with both HSV-1 and HSV-2 in 4 patients (30.8%). Recurrence of lesions was found to occur when the patient had HSV-2 or a mixed infection, but not the HSV-1 infection. Of 5 patients who underwent IIF and NM-PCR simultaneously, the virus was detected by NM-PCR only, not by IIF after viral culture, in 2 of the patients. CONCLUSION: HSV-1 infection as a cause of genital herpes is increasing, but recurrence is more common in HSV-2 infection. This study demonstrates that HSV-1 and HSV-2 can be detected simutaneously in the same anatomic region of genital herpes, and that NM-PCR is a more sensitive method for the detection and typing of HSV than IIF after viral culture.
Coinfection ; Fluorescent Antibody Technique, Indirect ; Herpes Genitalis* ; Herpesvirus 1, Human ; Herpesvirus 2, Human ; Humans ; Korea ; Polymerase Chain Reaction ; Recurrence ; Sexually Transmitted Diseases ; Simplexvirus

Proliferating trichilernmal tumor is a rare benign solitary tumor that may be histopathologically misinterpreted as squarnous cell carcinoma. It affects frequently the scalp of elderly women. We present herein a case of proliferating trichilemmal tumor in an 87-year-old male who had had a slowly growing tumor on the scalp for 30 years.
Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Scalp

No abstract available.

Pigmented spindle cell nevus was described as a variant of spindle and epithelioid cell nevus (Spitz nevus). However, it hs been classified as a separate disease because of the presence of large pigmented cells confined to the epidermis and papillary dermis. Pigmented epithelioid cell nevus is considered as a counterpart to pigmented spindle cell nevus, because it has similar clinicopathologic features to those of pigmented spindle cell nevus, except for tumor cells being entirely composed of large epithelioid cells. Herein, we report a case of a 31 year-old woman with a deeply-pigmented nodule which was entirely composed of large epithelioid cells, and showed many histologic findings of pigmented epithelioid cell nevus.
Adult ; Dermis ; Epidermis ; Epithelioid Cells* ; Female ; Humans ; Nevus* ; Nevus, Epithelioid and Spindle Cell ; Nevus, Spindle Cell

No abstract available.
Education ; Humans