1.Effects of Capsaicin Pretreatment on Lung Colonization of B16 Melanoma and mRNA Expressions for Some Cytokines in Mice.
Hyun Joo HA ; Jae Seung PARK ; Dae Yoo HA
Korean Journal of Immunology 2000;22(3):123-130
No abstract available.
Animals
;
Capsaicin*
;
Colon*
;
Cytokines*
;
Lung*
;
Melanoma, Experimental*
;
Mice*
;
RNA, Messenger*
2.Growth hormone response to peripheral infusion of clonidine in patients with panic disorder, major depression and alcohol dependence(1 ).
Joo Jin KIM ; Dong Hyun AHN ; Tae Hyuk YOO
Journal of Korean Neuropsychiatric Association 1992;31(3):488-498
No abstract available.
Clonidine*
;
Depression*
;
Growth Hormone*
;
Humans
;
Panic Disorder*
;
Panic*
3.Immunohistochemical Study of S-100 Protein in Salivary Gland Tumors.
Hyun Yeung KANG ; Dong Wook RYANG ; Joo Yong YOO
Korean Journal of Pathology 1986;20(4):427-434
An immunohistochemistry for S-100 protein by biotin avidin system technique was done to evaluate the existence and distribution pattern of S-100 protein positive cells in various obtained were as follows. 1) Positive immunostaining for S-100 protein was observed in myoepithelial cell, serous acinar cell and nervous bundle in normal salivary gland. 2) Strong immunoreactivity for S-100 protein was shown in plemorphic adenoma, which was localized not only in myoepithelial cord or sheets of epithelial portion but also in chondrocytes, stellate cells of myxoid stroma and in squamous keratin pearl of mesenchymal metaplastic foci. 3) The S-100 protein was demonstrated in the tumor cells of tubular adenoma, acinic cell tumors and in epidermoid area of mucoepidermoid tumors. 4) Immunoreactivity for S-100 protein, however, was not found in the tumor cells of adenoid cystic carcinoma and adenolymphoma except for stroma reticulum cells. 5) Intensity of positive reaction for S-100 protein varied from cell to cell: Some had intense immunoreactivity, whreas others were only weakly positive or completely negative, even in myoepithelial cell nest of the same pleomorphic adenoma.
4.Identification of Differentially Expressed Genes in Human Fetal Astrocytes.
Hye Myung YOO ; Hyun Sook PARK ; Hyun Chul CHO ; Choon Myung KOH ; Joo Young PARK
Journal of the Korean Society for Microbiology 2000;35(5):374-374
No Abstract Available.
Astrocytes*
;
Humans*
5.Estimation of creatinine clearance and urinary creatinine derived from plasma creatinine and body anthropometries.
Hyun Joo KWAK ; Young Guk KIM ; Keun Haeng CHO ; Kee Hwan YOO ; Soon Kyum KIM
Korean Journal of Nephrology 1993;12(3):286-294
No abstract available.
Creatinine*
;
Plasma*
6.Herpes Zoster in the Patients with Malignant Tumor.
Joo Heung REE ; Kwang Hyun CHO ; Hee Chul EUN ; Yoo Shin LEE ; Myoung Hee PARK
Korean Journal of Dermatology 1988;26(5):671-679
A study was made of the differences in clinical features and immunological aspects between herpes zoster patients with malignancies and those without malignant tumors. The results obtained from the retrospective review of medical records are as follows: Herpes zoster occurred more frequently in younger patients(less than twenty) with malignanciee as compared with the control group of the same ages,' Male was dominant among zoster patients with malignancies as is the contrary to contral group; Tihere were no marked differences in primarilly involved dermatomes between the two groups; Generalized varicelliform eruptiona were more common in zoster pa,tients with malignaneies than in control group, It seemed that zoster patients with malignancies complained of milder degree of pain. Zoeter patienta associated with malignancies were more frequently DNCB-negative and had decreased OKT3+ pan T cells, OKT4+ helper/inducer T cells as compared with control group, which suggest impaired cell mediated immunity in the former.
Herpes Zoster*
;
Humans
;
Immunity, Cellular
;
Male
;
Medical Records
;
Retrospective Studies
;
T-Lymphocytes
7.Reconstruction of the cervical esophagus using the free jejunal graft.
Chung Hyun CHI ; Won Kon KIM ; Kyu Seok CHO ; Joo Chul PARK ; Seh Yong YOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(12):1232-1237
No abstract available.
Esophagus*
;
Transplants*
8.An Evaluation of Sunscreen Efficacy Using Mouse Ear Swelling Reaction.
Joo Hyun CHOI ; Jai Il YOUN ; Ai Young LEE ; Jeong Aee KIM ; Yoo Shin LEE
Korean Journal of Dermatology 1990;28(4):419-424
This study was undertaken to investigate the efficacy of 5% PABA cream using mouse ear swelling reaction(ESR). Mice were exposed to 100mJ/cm of UVB, five times a week for four weeks, on the both ventral aspect of the ear, with application of 5% PABA cream on the right ear. The results were as follows : 1. The intensity of ear swelling reaction of 5% PABA protected group was reduced greater than unproteeted group after the first 3 days of UUR. 2. The intensity of ear swelling reached at peak after 1 week of the ultraviolet radiation. Thereafter it has decreased gradually the following 4 weeks. The difference of ear swelling between the two groups was the greatest after 1 week, and the sunscreening efficacy of 5% PABA cream has remained persisted for 4 weeks. 3. The number of mice which have shown severe inflarnmatory response after ultravioiet radiation was more in unprotected group than that in 5% PABA protected group. 4. Determination of mouse ESR is considered a good method for the evaluation of longterm efficacy of sunscreen preparation.
4-Aminobenzoic Acid
;
Animals
;
Ear*
;
Mice*
9.Two Cases of Clothing Dermatitis.
Joo Hyun CHOI ; Dae Hun SUH ; Ai Young LEE ; Yoo Shin LEE
Korean Journal of Dermatology 1990;28(6):765-768
Clothing dermatitis is a rare disease. The distribution of the eruption coincides with the places on the skin where the garment fits most snugly. It is developed by the chemicals and the dyes rather than textile itself. We experienced 2 cases of clothing dermatitis, one of which was caused by formaldehyde in clothing.
Clothing*
;
Coloring Agents
;
Dermatitis*
;
Formaldehyde
;
Rare Diseases
;
Skin
;
Textiles
10.The Studies of bcl-2 Oncoprotein and Epstein-Barr Virus Expression in Malignant Lymphomas: Immunohistochemical and in situ hybridization analysis on 66 cases.
Hye Jae CHO ; Yeon Mee KIM ; Hyun Ju YOO ; Jong Eun JOO
Korean Journal of Pathology 1996;30(2):121-131
Bcl-2 oncoprotein is being localized to mitochondria and interfering with programmed cell death (apoptosis) independent of promoting cell division in the lymphoid and nonlymphoid cells. The bcl-2 oncoprotein expression has been reported in follicular lymphomas as well as in diffuse non-Hodgkin's lymphoma, leukemia and a variable propotion of Hodgkin's lymphoma cases. Recent evidence suggests that some lymphomas protected from apoptosis is conferred through expression of Epstein-Barr virus(EBV) latent membrane protein which turn to cause upregulation of bcl-2. To define the role of the bcl-2 oncoprotein and EBV in lymphoid malignancy, we tried immunohistochemical studies with anti-bcl-2 antibody and In situ hybridization (ISH) with EBV-encoded small nuclear RNAs(EBER) in the paraffin embedded sections of 46 non-Hodgkin's lymphoma (NHL) cases and 20 Hodgkin's lymphoma (HL) cases. Bcl-2 oncoprotein expression was found in 37 of 46 cases (80%) of NHL with relatively strong cytoplasmic staining, and in 14 of 20 cases (70%) of HL with weak cytoplasmic staining in limited small numbers of RS, Hodgkin and lacunar cells. The widespread presence of bcl-2 oncogene in many different types of both NHL and HL supports that the extended cell survival through overexpression of bcl-2 gene protein may be a growth advantage of neoplastic lymphoid cells. In the ISH analysis for EBV, the presence of EBV was detected in 17 of 20 cases (85%) of HL, compared to 6 of 44 cases(13.6%) of NHL. It appears to be no direct correlation between overexpression of bcl-2 oncoprotein by neoplastic lymphoid cells and the presence of EBV in NHL but it seems to be a definite association between EBV and HL.