1.A Clinical Study of Androgenetic Alopecia (III).
Joo Hyun SHIM ; Sung Wook RO ; Byung In RO
Annals of Dermatology 2002;14(1):11-17
BACKGROUND: Androgenetic alopecia is considered to be a genetically determined disorder influenced by age and androgen. The proportion of patients with androgenetic alopecia among the total number of patients with alopecia seems to be gradually increasing. OBJECTIVES: The purpose of this study is to evaluate the family history,clinical and endocrine status of the patients with androgenetic alopecia. METHODS: 1113 patients with androgenetic alopecia who had visited the Department of Dermatology, Yongsan Hospital, College of Medicine,Chung-Ang University during the 3 years (1995.1-1998. 12) have been examined. RESULTS: The results are summarized as follows 1) The incidence of androgenetic alopecia among the total number of alopecia patients was 64.5%, showing recent increment. 2) There were 855 male and 258 female patients being most prevalent in the third decade in both sexes and the patients younger than 30 years old with premature androgenetic alopecia,made up 70.3% of the male patients and 48.8% of the female patients with androgenetic alopecia. 3) While Norwood's type Iia was the most common and following type II, III vertex,and IV in the male AGA, Ludwig's type II was the most common in female AGA 4) There was a family history of baldness in 53.5% of first degree relatives in male patients and 51.6%in female patients. 5)Associated diseases were observed in 565(66.8%) of the male patients and 219 (84.8%) of the female patients:diseases associated with androgen such as seborrheic dermatitis and acne vulgaris occupied 39.1%. CONCLUSION: Based on our findings, those who want to treat androgenetic alopecia at the earlier ages are gradually increasing and it seems to be reasonable to believe that the age, genetic factors, localized effects of androgens on the scalp and the density and/or functional activity of androgen receptors may influence the pathogenesis of androgenetic alopecia.
Acne Vulgaris
;
Alopecia*
;
Androgens
;
Clinical Study*
;
Dermatitis, Seborrheic
;
Dermatology
;
Female
;
Humans
;
Incidence
;
Male
;
Receptors, Androgen
;
Scalp
;
Testosterone
2.Requirement of B7 Molecule in Activation of Dendritic Epidermal T Cell by Transformed Keratinocyte.
Joo Hyun SHIM ; Seung Jun SEO ; Chang Kwun HONG
Korean Journal of Immunology 2000;22(4):217-223
No abstract available.
Keratinocytes*
3.Magnetic resonance angiographic screening of aneurysms in migraine
Minjung Oh ; Keon-Joo Lee ; Hyun Jung Oh ; Hyun Jung Park ; Jiyoung Shim ; Manho Kim
Neurology Asia 2014;19(2):171-177
Objective: The purpose of the present study was to screen the prevalence of aneurysms in migraineurs; to differentiate presenting features in migraineurs with and without aneurysm; and also to correlate the locations of aneurysm to the clinical features of migraine. Methods: A total of 4,416 subjects were interviewed and completed self-reported questionnaires on headache. Of these, 1,773 subjects diagnosed to have migraines based on the International Classification of Headache Disorders II (ICHD-II) criteria were screened for aneurysm by magnetic resonance angiography (MRA). When aneurysm was suspected, further investigation with trans femoral cerebral angiography (TFCA) or three dimensional computerized tomography (CT) angiography was performed. Based upon MRA findings, subjects were grouped into unruptured aneurysm migraine patients (UAMP) and no aneurysm migraine patients (NAMP). Results: The prevalence of aneurysm was 3.6% (63 of 1,773) with the mean age of 56.0 years, which were not different from those of general population. There was no difference in migraine subtypes between UAMP and NAMP. Aggravation of headache by estrogen replacement therapy during menopause (p=.039), history of migraine in young age (p= .021), diplopia (p=.026), and retroauricular pain (p=.025) were significantly associated with presence of aneurysm. Although aneurysms were detected more in anterior circulation, there was no correlation between aneurysm site and headache location. The average size of aneurysm was 3.5 ± 2.1 mm and none were ruptured. Interventional therapy of aneurysm did not alter the feature of migraine. Conclusions: The incidence of aneurysm was not different in migraine patients as compared to the general population. Some features which significantly differentiate whether migrainuers have aneurysm or not warrant further study to have a predictive and localizing value.
4.Current status and future perspectives of capsule endoscopy.
Intestinal Research 2016;14(1):21-29
Small bowel capsule endoscopy (CE) was first introduced 15 years ago, and a large amount of literature has since been produced, focused on its indication, diagnostic yields, and safety. Guidelines that have made CE the primary diagnostic tool for small bowel disease have been created. Since its initial use in the small bowel, CE has been used for the esophagus, stomach, and colon. The primary indications for small bowel CE are obscure gastrointestinal bleeding, unexplained iron deficiency anemia, suspected Crohn's disease, small bowel tumors, nonsteroidal anti-inflammatory drug enteropathy, portal hypertensive enteropathy, celiac disease, etc. Colon CE provides an alternative to conventional colonoscopy, with possible use in colorectal cancer screening. Guidelines for optimal bowel preparation of CE have been suggested. The main challenges in CE are the development of new devices with the ability to provide therapy, air inflation for better visualization of the small bowel, biopsy sampling systems attached to the capsule, and the possibility of guiding and moving the capsule by an external motion controller. We review the current status and future directions of CE, and address all aspects of clinical practice, including the role of CE and long-term clinical outcomes.
Anemia, Iron-Deficiency
;
Biopsy
;
Capsule Endoscopy*
;
Celiac Disease
;
Colon
;
Colonoscopy
;
Colorectal Neoplasms
;
Crohn Disease
;
Esophagus
;
Hemorrhage
;
Inflation, Economic
;
Intestine, Small
;
Mass Screening
;
Stomach
5.The Stress Perception, Depressive Symptoms and Medical Comorbidity in Healthcare Center.
In Bo SHIM ; Sook Haeng JOE ; Byung Joo HAM ; Changsu HAN ; Hyun Ghang JEONG ; Young Hoon KO
Korean Journal of Psychosomatic Medicine 2013;21(1):27-43
OBJECTIVES: We surveyed this study for knowing the relation within stress, depression and medical comorbidities, and finding the risk factors of major depression. METHODS: 1764 subjects were enrolled from Jan. 2009 to Dec. 2009 who visit Korea University Guro hospital healthcare center. The subjects answered the questionnaire of PSS(Perceived Stress Scale), PHQ-9(Patient Health Questionnaire-9) and the demographic data. We categorized them as the stress group, depressive group, medical comorbidity group and analyzed the correlation analyses and logistic regression analyses. RESULTS: 198 of 1764 subjects(11.8%) were applied to major depression, and the depressive group showed the higher mean stress score(23.19) and mean depression score(12.95) than the normal group. The total PHQ-9 score was increased by perceiving more stress, having more medical comorbidities. The subjects with female, visiting due to recent health problems, irregular exercise, current smoking, history of angina and cerebrovascular disease showed the increased risk of major depression. CONCLUSIONS: In this study, we find the PSS, PHQ-9 were valuable for mental health screening in healthcare center. As perceiving more stress and having more medical comorbidity, risk of major depression were increased. Accordingly the individuals with medical diseases or unhealthy lifestyle would need the mental health screen.
Comorbidity
;
Delivery of Health Care
;
Depression
;
Female
;
Humans
;
Korea
;
Life Style
;
Logistic Models
;
Mass Screening
;
Mental Health
;
Questionnaires
;
Risk Factors
;
Smoke
;
Smoking
6.A Case of Multiple Plexiform Schwannomas.
Joo Hyun SHIM ; Tae Jong CHUN ; Myeung Nam KIM ; Kye Yong SONG ; Byung In RO
Annals of Dermatology 2000;12(2):130-133
Plexiform schwannoma is a relatively rare, benign peripheral nerve sheath tumor that can be located either in the deep soft tissues or in the dermis or subcutaneous tissue. This tumor may occur singly or as multiple lesions and may be localized to one anatomic site or diffusely distributed. Plexiform schwannoma should be differentiated with plexiform neurofibroma or other plexiform malignant tumors. We describe a case of a 6-year-old patient with multiple cutaneous plexiform schwannomas who had no other stigmata of neurofibromatosis 1 or family history suggesting a genetic disorder. The histopathological study revealed a tumor composed of multiple intradermal or subcutaneous interlacing and interconnecting fascicles and nodules that vary in size and shape. Characteristic Antoni A type cellular tissue showing frequent nuclear palisading and Verocay bodies were observed within well circumscribed elongated nodules.
Child
;
Christianity
;
Dermis
;
Humans
;
Neurilemmoma*
;
Neurofibroma, Plexiform
;
Neurofibromatosis 1
;
Peripheral Nerves
;
Subcutaneous Tissue
7.What Is the Optimal Timing of Bowel Preparation for Video Capsule Endoscopy?.
Clinical Endoscopy 2015;48(3):183-184
No abstract available.
Capsule Endoscopy*
8.What Is the Optimal Timing of Bowel Preparation for Video Capsule Endoscopy?.
Clinical Endoscopy 2015;48(3):183-184
No abstract available.
Capsule Endoscopy*
9.A Case of Zoster Duplex Bilateralis.
Bong Ju SHIN ; Joo Hyun SHIM ; Seong Jun SEO ; Chang Kwun HONG
Annals of Dermatology 2002;14(1):59-62
Herpes zoster involving noncontiguous dual dermatomes is very rare in both immunocompetent and immunocompromised persons. This unique presentation has been referred to as zoster duplex unilateralis or bilateralis, depending whether one or both halves of the body are involved. A 22-year-old woman, who had been treated for acute leukemia, congestive heart failure and chronic disseminated candidiasis, was referred to our department for painful papulovesicular eruptions on the right side of the anterior chest and upper back for 2 days, and the left buttock for 1 day. Tzanck smear revealed multinucleated giant cells with intranuclear inclusion bodies. We report a rare case of zoster duplex bilateralis.
Buttocks
;
Candidiasis
;
Female
;
Giant Cells
;
Heart Failure
;
Herpes Zoster*
;
Humans
;
Intranuclear Inclusion Bodies
;
Leukemia
;
Thorax
;
Young Adult
10.Surgical resection of tracheal leiomyoma: A case Report.
Jae Chun SHIM ; Suk Joo RHA ; Keon Hyun JO ; Moon Sub KWACK ; Se Hwa KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(12):965-968
No abstract available.
Leiomyoma*