1.Cancer Gene Therapy.
Journal of the Korean Medical Association 1998;41(8):836-840
No abstract available.
Genes, Neoplasm*
2.MIC and MBC of oral antimicrobial agents against staphylococcus aureus.
Min Hang KIM ; Jin Won PARK ; Yun Joo CHEUNG ; Kung Sik RYOO ; Myung Woong CHANG
Journal of the Korean Pediatric Society 1992;35(5):659-666
No abstract available.
Anti-Infective Agents*
;
Staphylococcus aureus*
;
Staphylococcus*
3.A Case of Bacteremia by Plesiomonas shigelloides.
Hyukmin LEE ; Kyungja WOO ; Kyungwon LEE ; Yunsop CHONG ; Joo Hang KIM
Korean Journal of Clinical Microbiology 2000;3(2):137-141
Plesiomonas shigelloides was isolated from blood culture of a 53-year-old man with fever, who had treatment history of gastrointestinal malignancy. The patient showed neither clinical features nor hematological finding which suggest bacteremia. Identification of the isolate was delayed because of its similar characteristics with Aeromonas spp. and other gram-negative bacilli. The isolate was misinterpreted as susceptible to ampicillin by the first disk diffusion test. It may not always easy to identify P. shigelloides by conventional tests and to determine its antimicrobial susceptibility accurately, as laboratorians rarely have experience with the organism and as the organism may show unusual inhibition pattern when tested by disk diffusion method or Etest.
Aeromonas
;
Ampicillin
;
Bacteremia*
;
Diffusion
;
Fever
;
Humans
;
Middle Aged
;
Plesiomonas*
4.A Case of Bacteremia by Plesiomonas shigelloides.
Hyukmin LEE ; Kyungja WOO ; Kyungwon LEE ; Yunsop CHONG ; Joo Hang KIM
Korean Journal of Clinical Microbiology 2000;3(2):137-141
Plesiomonas shigelloides was isolated from blood culture of a 53-year-old man with fever, who had treatment history of gastrointestinal malignancy. The patient showed neither clinical features nor hematological finding which suggest bacteremia. Identification of the isolate was delayed because of its similar characteristics with Aeromonas spp. and other gram-negative bacilli. The isolate was misinterpreted as susceptible to ampicillin by the first disk diffusion test. It may not always easy to identify P. shigelloides by conventional tests and to determine its antimicrobial susceptibility accurately, as laboratorians rarely have experience with the organism and as the organism may show unusual inhibition pattern when tested by disk diffusion method or Etest.
Aeromonas
;
Ampicillin
;
Bacteremia*
;
Diffusion
;
Fever
;
Humans
;
Middle Aged
;
Plesiomonas*
5.A prevalence study of pulmonary tuberculosis in hospital visited diabetes patients
Ho Keun CHUNG ; Hang Young LEE ; Kyung Bin JOO ; Kun Sang KIM
Journal of the Korean Radiological Society 1983;19(4):693-696
We reviewed the records of randomly selected 320 diabetic out-patients af Eul-ji Hospital from April 1981through March 1983. Fasting blood sugar (FBS) of 140 mg/dl or more was taken as a criteria of diabetses accordingto the report of National Diabetes Data Group. The resuls are as follows: 1. Mean age of study group was 50.8years-old and the FBS mean value was 22.4 mg/dl. 2. There was no siginificant difference of FBS values oftuberculosis and non-tuberculosis patients . 3. Prevalence of pulmonary tuberculosis evaluated by chest films was13.4 percent in diabetes patients. This value is lower than those of other studies but higher than that of urbanpopulation in Korea (p<0.05).
Blood Glucose
;
Cross-Sectional Studies
;
Fasting
;
Humans
;
Korea
;
Outpatients
;
Prevalence
;
Thorax
;
Tuberculosis, Pulmonary
6.Therapeutics Approaches in the Treatment of Limited Small-Cell Lung Cancer.
Cancer Research and Treatment 2002;34(6):403-404
No abstract available.
Lung Neoplasms*
;
Lung*
7.Clinicopathological Analysis of Female Gastric Cancer - Comparative study according to the sex fo the patients.
Jin Pok KIM ; Hang Jong YU ; Young Chul KIM ; Soo Jin KIM ; Joo Ho LEE ; Han Kwang YANG
Journal of the Korean Cancer Association 1998;30(5):879-885
PURPOSE: The purpose of this study is to evaluate the differences of the clinicopathological features and survival rates in gastric cancer according to the sex of the patients. MATERIALS AND METHODS: We reviewed 5,784 cases of gastric cancer patients who underwent laparotomy at the Department of Surgery, Seoul National University Hospital fmm Jan. 1986 to Dec. 1995. We have analyzed clinicopathologic features including tumor location, Bonmann type, depth of invasicm, lymph node metastasis, distant metastasis, TNM stage, histologic differentiation and survival rates according to the sex of the patients. RESULTS: The mean age of female patients was 52.4 years, which is lower than that of male, 54.8 years. There were no differences in tumor location, Borrmann type, depth of invasion, lymph node metastasis, distant metastasis, TNM stage of tumor between male and female. But there were some differences in histologic differentiation; well- and moderately differentiated cancers were more common in male and signet-ring cell cancers were more common in female. Female shows slightly better prognosis than male. But the prognosis of young female was poorer than that of young male. CONCLUSION: In gastric cancer patients, differences in histologic differentiation and more aggressive nature of the signet-ring cell cancer in female may affect the survival differences according to the sex.
Female*
;
Humans
;
Laparotomy
;
Lymph Nodes
;
Male
;
Neoplasm Metastasis
;
Prognosis
;
Seoul
;
Stomach Neoplasms*
;
Survival Rate
8.Phase II Study of Topotecan and Etoposide as Second-line Treatment in Chemotherapy-refractory Small-cell Lung Cancer.
Chul KIM ; Joo Hyuk SOHN ; Joo Hang KIM ; Se Kyu KIM ; Young Sam KIM ; Joon CHANG ; Jae Yong CHO
Cancer Research and Treatment 2002;34(5):334-338
PURPOSE: Refractory small-cell lung cancer (SCLC) has a poor prognosis, and current salvage chemotherapy for refractory SCLC, such as CAV (cyclophosphamide, adriamycin, vincristine) or topotecan, has an unsatisfactory outcome, with a response rate and overall survival of less than 10% and 6 months, respectively. This phase II study evaluated the role of topotecan combined with etoposide in SCLC patients that have progressed, or relapsed, within 3 months following completion of the initial chemotherapy. MATERIALS AND METHODS: Twenty-seven patients were entered into this study. Eligible patients had an ECOG performance status of less than, or equal to, 2, at least one bidimensionally measurable lesion and adequate end organ function. IV topotecan, 1.0 mg/m2/d for 5 consecutive days, and etoposide, 100 mg/m2/d through days 1 to 3, were administered every 3 weeks until disease progression or undue toxicity. RESULTS: The major toxicity was myelosuppression. Grade 3/4 anemia, granulocytopenia, and thrombocy-topenia occurred in 14.2, 34.8, and 27.3% of cycles, respectively. There was no treatment-related death, and other non-hematologic toxicities were generally mild. Four patients achieved partial responses, with a response rate RR of 14.8%. The progression-free survival PFS ranged from 1 to 7 months, with a median of 2.0 months (95% confidence interval 1.22~2.78 months). Twenty-five patients died, with a median overall survival of 5.5 months (ranging from 1 to 21 months, 95% CI 4.32~6.68 months), and the 6-month survival rate was 32.1% (95% confidence interval 14.4~49.8%). CONCLUSION: The combination of topotecan and etoposide chemotherapy showed a modest response rate, but failed to prolong survival of refractory SCLC patients compared to topotecan monotherapy.
Agranulocytosis
;
Anemia
;
Carcinoma, Small Cell
;
Disease Progression
;
Disease-Free Survival
;
Doxorubicin
;
Drug Therapy
;
Drug Therapy, Combination
;
Etoposide*
;
Humans
;
Lung Neoplasms*
;
Lung*
;
Prognosis
;
Survival Rate
;
Topotecan*
9.Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy.
Kyung Mo KIM ; Soo Jong HANG ; Young Seo KIM ; Hyung Nam MOON ; Chang Yee HONG ; Joo Ryoung HUH
Journal of the Korean Pediatric Society 1995;38(9):1232-1241
No abstract available.
Child*
;
Hepatitis B, Chronic*
;
Hepatitis, Chronic*
;
Humans
;
Interferon-alpha*
10.Effect of surgical timing and outcomes for appendicitis severity.
Maru KIM ; Sung Jeep KIM ; Hang Joo CHO
Annals of Surgical Treatment and Research 2016;91(2):85-89
PURPOSE: This study was aimed to evaluate the effect of time of surgery for acute appendicitis on surgical outcomes to optimize the timing of appendectomies. METHODS: Medical records of patients who underwent an appendectomy were reviewed to obtain data on time of symptom onset, time of hospital presentation, and start times of surgery. Surgical findings were used to define appendicitis as either uncomplicated or complicated. The uncomplicated group included patients with simple, focal, or suppurative appendicitis, and the complicated group included patients with gangrenous, perforated appendicitis or periappendiceal abscess formation. The 2 groups were analyzed by age, sex, and time. RESULTS: A total of 192 patients were analyzed. The mean time from symptom onset to start of operation showed a significant difference between both groups (1,652.9 minutes vs. 3,383.8 minutes, P < 0.001). The mean time from hospital visit to start of operation showed no difference between both groups (398.7 minutes vs. 402.0 minutes, P = 0.895). Operating within 24 hours of symptom onset had a relative risk of 1.738 (95% confidence interval, 1.319-2.425) for complications. Operating more than 36 hours after symptom onset was associated with an increased risk of postoperative ileus and a longer hospital stay. CONCLUSION: Complicated appendicitis is associated with a delay in surgery from symptom onset rather than a delay at hospital arrival. Surgeons should take into account the time from symptom onset when deciding on the timing of appendectomy. We recommend that appendectomy be performed within 36 hours from symptom onset.
Abscess
;
Appendectomy
;
Appendicitis*
;
Humans
;
Ileus
;
Length of Stay
;
Medical Records
;
Surgeons
;
Treatment Outcome