Gonadoblastoma occurs almost always in association with a Y chromosome cell line, and developes in one third of patients with Mixed gonadal dysgenesis. Removing of gonads of intersex patients with the Y chromosome is very important because of the strong association of the genesis of tumor in dysgenetic gonads with the presence of a Y chromosome. But it is always possible that an XY cell line could be missed, or that a fragment from Y chromosome could have been translocated and not discovered by chromosomal analysis. PCR with Y specific probe or Southern blotting would reveal the presence of a Y or a translocated fragment. We experienced an 18-year-old woman represent with primary amenorrhea who had 45,X/46,X,+mar. Y-specific PCR revealed that the marker chromosome was drived from Y chromosome. After both gonadectomy and clitorial recession, we found the gonadoblastoma in dysgenetic testis. So we report it with brief review of literatures.
Adolescent ; Amenorrhea ; Blotting, Southern ; Cell Line ; Female ; Gonadal Dysgenesis, Mixed* ; Gonadoblastoma* ; Gonads ; Humans ; Polymerase Chain Reaction ; Testis ; Y Chromosome

Background: The socioeconomic burden of musculoskeletal disorders (MSDs) is significant, and kitchen work is a high-risk occupation for MSDs due to the intensive manual workload and repetitive movements that are involved. However, there are very few studies on MSDs and rest breaks as a workplace intervention among kitchen workers. This study examined the relationship between insufficient rest breaks and increased MSD risk among Korean kitchen workers. Methods: Sociodemographic and occupational factors of 1,909 kitchen workers were collected from the 3rd–4th Korean Working Conditions Survey data. Five items on rest breaks at work were categorized into two groups, “sufficient” and “insufficient.” The number of MSDs and work-related MSDs (WMSDs), an outcome variable, was obtained from the sum of MSDs/WMSDs in three anatomical sites (back, neck, and upper limb, lower limb). The association between rest breaks and MSDs was estimated using zero-inflated negative binomial analyses, with adjustments for age, education level, and weekly working hours, and the analyses were stratified by sex. Results: After adjustment, significant associations were found between insufficient rest breaks and an increased risk of MSDs (odds ratio [OR] 1.68 95% confidence interval [CI] 1.11–2.54) and WMSDs (OR 1.40 95% CI 1.01–1.96) among female kitchen workers. Insufficient rest breaks were significantly associated with MSDs in female kitchen workers in all three anatomical sites. Conclusion This study emphasizes the need for rest breaks as a workplace intervention for preventing MSDs in kitchen workers. Further studies to reveal the causality of this relationship are required.

Background: The socioeconomic burden of musculoskeletal disorders (MSDs) is significant, and kitchen work is a high-risk occupation for MSDs due to the intensive manual workload and repetitive movements that are involved. However, there are very few studies on MSDs and rest breaks as a workplace intervention among kitchen workers. This study examined the relationship between insufficient rest breaks and increased MSD risk among Korean kitchen workers. Methods: Sociodemographic and occupational factors of 1,909 kitchen workers were collected from the 3rd–4th Korean Working Conditions Survey data. Five items on rest breaks at work were categorized into two groups, “sufficient” and “insufficient.” The number of MSDs and work-related MSDs (WMSDs), an outcome variable, was obtained from the sum of MSDs/WMSDs in three anatomical sites (back, neck, and upper limb, lower limb). The association between rest breaks and MSDs was estimated using zero-inflated negative binomial analyses, with adjustments for age, education level, and weekly working hours, and the analyses were stratified by sex. Results: After adjustment, significant associations were found between insufficient rest breaks and an increased risk of MSDs (odds ratio [OR] 1.68 95% confidence interval [CI] 1.11–2.54) and WMSDs (OR 1.40 95% CI 1.01–1.96) among female kitchen workers. Insufficient rest breaks were significantly associated with MSDs in female kitchen workers in all three anatomical sites. Conclusion This study emphasizes the need for rest breaks as a workplace intervention for preventing MSDs in kitchen workers. Further studies to reveal the causality of this relationship are required.

In order to develop a Patient respiratory management system includinga biofeedback function for4-dimentional radiation therapy, this study investigated anoptimal tracking algorithmfor moving target using IR (Infra-red) camera as well as commercial camera. A tracking system was developed by LabVIEW 2010. Motion phantom images were acquired using a camera (IR or commercial). After image process were conducted to convert acquired image to binary image by applying a threshold values, several edge enhance methods such as Sobel, Prewitt, Differentiation, Sigma, Gradient, Roberts, were applied. The targetpattern was defined in the images, and acquired image from a moving targetwas tracked by matching pre-defined tracking pattern. During the matching of imagee, thecoordinateof tracking point was recorded. In order to assess the performance of tracking algorithm, the value of score which represents theaccuracy of pattern matching was defined. To compare the algorithm objectively, we repeat experiments 3 times for 5 minuts for each algorithm. Average valueand standard deviations (SD) of score were automatically calculatedsaved as ASCII format. Score of threshold only was 706, and standard deviation was 84. The value of average and SD for other algorithms which combined edge detection method and thresholdwere 794, 64 in Sobel, 770, 101 in Differentiation, 754, 85 in Gradient, 763, 75 in Prewitt, 777, 93 in Roberts, and 822, 62 in Sigma, respectively. According to score analysis, the most efficient tracking algorithm is the Sigma method. Therefore, 4-dimentional radiation threapy is expected tobemore efficient if threshold and Sigma edge detection method are used together in target tracking.
Biofeedback, Psychology ; Humans ; Track and Field

OBJECTIVES: We aimed to ascertain the relationship between several factors and successful return to work using a structural equation model. METHODS: We used original data from the Panel Study of Worker's Compensation Insurance, and defined four latent variables as occupational, individual, supportive, and successful return to work. Each latent variable was defined by its observed variables, including age, workplace size, and quality of the medical services. A theoretical model in which all latent variables had a relationship was suggested. After examining the model, we modified some pathways that were not significant or did not fit, and selected a final structural equation model that had the highest goodness of fit. RESULTS: All three latent variables (occupational, individual, and supportive) showed statistically significant relationships with successful return to work. The occupational and supportive factors had relationships with each other, but there was no relationship between individual and the other factors. Nearly all observed variables had significance with their latent variables. The correlation coefficients from the latent variables to successful return to work were statistically significant and the indices for goodness of fit were satisfactory. In particular, four observed variables-handicap level, duration of convalescence, working duration, and support from the company-showed construct validities with high correlation coefficients. CONCLUSIONS: All factors that we examined are related to successful return to work. We should focus on the supportive factor the most because its variables are modifiable to promote a return to work by those injured in their workplace.
Convalescence ; Insurance ; Models, Theoretical ; Return to Work* ; Workers' Compensation

Background: This study investigates the safety and health status of geographically isolated and confined workers. Methods: This study was conducted in Baekryeong Island in Korea in 2020. The agestandardized prevalence ratios (aSPR) for occupational injury, unmet medical needs, psychological status, and lifestyle were estimated from the available data. Also, we compared the aSPRs of workers in Baekryeong Island with a reference study population who participated in a nationally representative survey in Korea. Results: The study revealed that Baekryeong Island workers had an increased risk of acquiring health and safety problems compared to the general worker population. The island workers showed a significant increase in unmet medical care (aSPR, 5.319; 95% confidence interval [CI], 3.984–6.958) and occupational injury (aSPR, 8.371; 95% CI, 3.820–15.892). Conclusion This study identified the safety and health problems of geographically isolated workers in Baekryeong Island. The risk of occupational injury and unmet medical care are simultaneously highlighted in the region's population, thereby underscoring the importance of prevention.

Background: This study investigates the safety and health status of geographically isolated and confined workers. Methods: This study was conducted in Baekryeong Island in Korea in 2020. The agestandardized prevalence ratios (aSPR) for occupational injury, unmet medical needs, psychological status, and lifestyle were estimated from the available data. Also, we compared the aSPRs of workers in Baekryeong Island with a reference study population who participated in a nationally representative survey in Korea. Results: The study revealed that Baekryeong Island workers had an increased risk of acquiring health and safety problems compared to the general worker population. The island workers showed a significant increase in unmet medical care (aSPR, 5.319; 95% confidence interval [CI], 3.984–6.958) and occupational injury (aSPR, 8.371; 95% CI, 3.820–15.892). Conclusion This study identified the safety and health problems of geographically isolated workers in Baekryeong Island. The risk of occupational injury and unmet medical care are simultaneously highlighted in the region's population, thereby underscoring the importance of prevention.

Background: Long working hours and caregiving responsibilities are prevalent in many societies. These demands can lead to stress and adverse mental health outcomes. This study examines the associations of long working hours and family caregiving on psychological well-being and their interactions among South Korean wage workers. Methods: Using data from the Korean Working Conditions Survey, this cross-sectional study involved 33,063 participants. Long working hours were categorized as 40 and 52 hours a week, and caregiving was assessed through self-reports of non-work-related caregiving activities. The World Health Organization Well-Being Index was used to measure psychological well-being, with Poisson regression models analyzing the associations and interactions between working hours, caregiving activities, and psychological well-being. Results: The prevalence of low psychological well-being was significantly higher among individuals with both long working hours and caregiving responsibilities than among those with either or neither stressor (adjusted prevalence ratio = 1.81; 95% confidence interval: 1.42–2.31, multiplicative scale = 1.32; 95% confidence interval: 1.00–1.73). Conclusion This study highlights the significant mental health implications of combining long working hours with caregiving responsibilities in the Republic of Korea. The synergistic interaction between these factors suggests that interventions and policies aimed at reducing work-related stress and supporting caregivers could have substantial benefits for mental health.

Background: Long working hours and caregiving responsibilities are prevalent in many societies. These demands can lead to stress and adverse mental health outcomes. This study examines the associations of long working hours and family caregiving on psychological well-being and their interactions among South Korean wage workers. Methods: Using data from the Korean Working Conditions Survey, this cross-sectional study involved 33,063 participants. Long working hours were categorized as 40 and 52 hours a week, and caregiving was assessed through self-reports of non-work-related caregiving activities. The World Health Organization Well-Being Index was used to measure psychological well-being, with Poisson regression models analyzing the associations and interactions between working hours, caregiving activities, and psychological well-being. Results: The prevalence of low psychological well-being was significantly higher among individuals with both long working hours and caregiving responsibilities than among those with either or neither stressor (adjusted prevalence ratio = 1.81; 95% confidence interval: 1.42–2.31, multiplicative scale = 1.32; 95% confidence interval: 1.00–1.73). Conclusion This study highlights the significant mental health implications of combining long working hours with caregiving responsibilities in the Republic of Korea. The synergistic interaction between these factors suggests that interventions and policies aimed at reducing work-related stress and supporting caregivers could have substantial benefits for mental health.

Background: Long working hours and caregiving responsibilities are prevalent in many societies. These demands can lead to stress and adverse mental health outcomes. This study examines the associations of long working hours and family caregiving on psychological well-being and their interactions among South Korean wage workers. Methods: Using data from the Korean Working Conditions Survey, this cross-sectional study involved 33,063 participants. Long working hours were categorized as 40 and 52 hours a week, and caregiving was assessed through self-reports of non-work-related caregiving activities. The World Health Organization Well-Being Index was used to measure psychological well-being, with Poisson regression models analyzing the associations and interactions between working hours, caregiving activities, and psychological well-being. Results: The prevalence of low psychological well-being was significantly higher among individuals with both long working hours and caregiving responsibilities than among those with either or neither stressor (adjusted prevalence ratio = 1.81; 95% confidence interval: 1.42–2.31, multiplicative scale = 1.32; 95% confidence interval: 1.00–1.73). Conclusion This study highlights the significant mental health implications of combining long working hours with caregiving responsibilities in the Republic of Korea. The synergistic interaction between these factors suggests that interventions and policies aimed at reducing work-related stress and supporting caregivers could have substantial benefits for mental health.