No abstract available.
Frontal Sinus*

Real-time ultrasongraphy is a simple, accurate, noninvasive and potentially valuable means of studying gallbladder size and emptying. The authors calculated ultrasonographically the ejection fraction of 80 cases of normally functioning gallbladder on oral cholecystography, from June 1983 to April 1984, at the department of radiology, Hangang Sacred Heart Hospital. The results were obtained as follows; 1. Ultrasongraphic Ejection Fraction at 30 minutes after the fatty meal was 73.1+-16.85. 2. There was no significant difference in age and sex, statistically.
Cholecystography ; Gallbladder ; Heart ; Meals

Although the peritoneum is rare site for a primary neoplasm, certain malignant neoplasms may arise from it. A case of 63-year-old woman who had a serous papillary carcinoma of peritoneal origin is reported. Extraovarian peritoneal serous papillary carcinoma was characterized by ascites, malignant washings, and omental involvement with bulky infiltration and/or multiple tumor nodules. The symptoms caused by diffuse spreading of the neoplasm over the peritoneum are the most important manifestation for clinical diagnosis of malignant primary neoplasm of peritoneum, especially serous papillary carcinoma. This behaving tumor was at least partially responded to therapy. In this report, we describe a case of serous papillary carcinoma of peritoneum carring on proper management with brief review.
Ascites ; Carcinoma, Papillary* ; Diagnosis ; Female ; Humans ; Middle Aged ; Peritoneum*

In recent years, early intervention is the paradigm in psychosis treatment. The logic of early intervention paradigm is based on the view that the earliest possible detection and intervention for psychosis will deliver the best outcome for patients. Therefore, in recent decades, most of studies focused on indentifying people with psychosis as early as possible, reducing the duration of untreated psychosis. However, while there are well documented and sometimes serious side effects associated with antipsychotic medication in the short-term, the iatrogenic risks of atypical antipsychotic medication are underscored. Furthermore, against this paradigm, the recent of longitudinal studies of schizophrenia suggest a new paradigm shift in treatment timing of psychosis. In this respect, this case which showed symptom remission after conversion into schizophrenia in early psychosis suggests wondering about the time of treatment. Similar cases have not been reported. And review of the effects of timing, in fact, has yet to be done. If similar cases would be reported in the future more, treatment timing may be the next paradigm shift in the therapeutics of early psychosis.
Antipsychotic Agents ; Early Intervention (Education) ; Humans ; Logic ; Longitudinal Studies ; Psychotic Disorders* ; Schizophrenia*

This review article aims to reveal the meaning and importance of economic evaluation in Korean mental health sector. The global burden of neuropsychiatric disorders, as measured by loss of disability-adjusted life years (DALYs), is estimated very high, irrespective of low mortality. There are several methods for such economic evaluation, including cost-effectiveness analysis (CEA), cost-utility analysis (CUA), and cost-benefit analysis (CBA), but there is still a paucity of such studies in the mental health sector. Economic evaluations of mental health in Korea can provide a rational basis to plan a national health policy regarding the global burden of diseases caused by psychiatric disorders.
Cost-Benefit Analysis ; Health Policy ; Korea ; Mental Health

The stigma of mental illness is a problem that should be addressed urgently as such stigma has a negative effect on the lives of individuals with mental disorders, which may result in social and economic losses. Moreover, mental health stigma acts as a barrier to mental health service utilization. Thus, the need to reduce the mental health stigma has been highlighted. In Korea, stigma associated with individuals with mental disorders has been studied; however, few of those studies investigated mental health literacy, which might influence an individual's attitudes toward and beliefs about people with mental disorders. Furthermore, there are fewer evidence-based anti-stigma campaigns and programs in Korea than in other countries. On that basis, a review of previous studies focusing on mental disorder stigma was undertaken, and the effects of such stigma on individuals with mental disorders and on society were assessed. In addition, research into mental health literacy, rarely undertaken in South Korea, was discussed. Finally, anti-stigma campaigns that are reportedly effective in reducing mental illness stigma were reviewed. With regard to future research on mental health stigma in South Korea, it is suggested that researchers study mental health literacy to assess accurately the public's misperceptions about mental disorders. In addition, a variety of evidence-based anti-stigma campaigns should be implemented to increase public knowledge of mental disorders. Lastly, cooperation between public and private sectors should be encouraged to develop strategies for reducing the stigma and negative beliefs associated with mental disorders.
Korea* ; Literacy ; Mental Disorders ; Mental Health ; Mental Health Services ; Private Sector

OBJECTIVES: In the current study, we investigated the general characteristics of suicide attempters and attempted to determine factors contributing to suicide attempt by analyzing severe suicide ideation and intent. METHODS: This study analyzed medical records of suicide attempters who visited the emergency departments. Data were collected from 7 university hospitals nationwide. As an evaluation measure of suicide intent, we used Suicide Intent Scale (SIS). Colombia Suicide Severity Rating Scale (C-SSRS) was applied for assessment of severity and intensity of suicide idea and lethality of suicide behavior. RESULTS: Male gender, old age and living alone group showed higher SIS score. Male gender, low income, and having psychiatric diagnosis or suicide history group showed a high score on the severity subscale of suicide ideation of C-SSRS. Old age, low income, and having psychiatric diagnosis showed a high score on the intensity subscale of suicide ideation of C-SSRS. Actual lethality scale of C-SSRS was high in male gender and old age group. Severity and intensity of suicide ideation and suicide intent showed positive correlation with actual lethality of suicide behavior. CONCLUSION: Male gender, old age, living alone, psychiatric diagnosis, and suicide history were risk factors affecting severity and intensity of suicide ideation and intent of suicide. Severity and intensity of suicide ideation and intent are positively related to lethality of suicide behavior.
Colombia ; Emergency Service, Hospital ; Hospitals, University ; Humans ; Male ; Medical Records ; Mental Disorders ; Risk Factors ; Suicide*

No abstract available.
Epinephrine* ; Skin* ; Transplants*

OBJECTIVES: The Children's Depression Inventory (CDI) is one of the most widely used self-report instruments for the assessment of childhood depression, and it has been especially valid for epidemiological purposes. The aim of this study is to assess self-reported depressive symptoms in 5th grade students in a small city by gender, using the Korean version of the CDI. In addition, factorial analysis was performed on the 27 items of the CDI in the subjects in order to identify potential composite dimensions. METHODS: The participants were 2,293 5th grade students from elementary schools (1,148 males and 1,145 females). The initial factors were extracted by maximum likelihood factor analysis and then rotated according to promax criteria in order to achieve a simple structure. Only those items with a loading of .30 or greater were included in the identified factors. RESULTS: The mean CDI score was 13.95+/-7.11. A total of 557 (24.3%) children showed clinically significant scores of more than 19 points. There was no significant difference in mean score between the boys and girls. Factorial analysis yielded four factors: dysphoria/biological dysregulation, externalizing/self-deprecation, social problems and school problems. The factor that accounted for the highest variability was externalizing/self-depreciation in boys and dysphoria/biological dysregulation in girls. CONCLUSION: The cut-off score on the CDI in children should be considered to be higher than that in previous studies. The factorial structure for 11-year-old children in Korea seems to be similar to that of adolescents in Western countries.
Adolescent ; Child ; Depression ; Factor Analysis, Statistical ; Humans ; Korea ; Male ; Social Problems

PURPOSE: Aberrant expression of the c-myb gene is often detected in transformed leukemic cells. Inhibition of c-myb expression by antisense oligos could be an effective way to abort rapid growth of leukemic cells. Developing stable antisense oligos combined with enhanced delivery into cells would be of great use in developing an effective anti-cancer molecular agent. MATERIALS AND METHODS: Selection of target sites was carried out by employing computer simulation of mRNA secondary structures. Multiple antisense oligo sequences were adjoined and AS-oligos were then covalently closed to evade exonuclease activities. C-myb antisense oligos with a novel structure were complexed with cationic liposomes and used to treat HL-60 leukemic cells. RESULTS: We developed covalently closed antisense oligos which harbor four adjoined antisense sequences. The c-myb antisense oligos were found to be exceptionally stable and effective in specifically ablating c-myb mRNA. The antisense oligos were able to inhibit growth of leukemic cell line (HL-60) by about 80%. Antisense effect was more pronounced when the cells were treated twice with the antisense oligos at lower concentrations. CONCLUSION: The novel covalently closed antisense oligo (CMAS-oligos) was found to be effective and exceptionally stable, Growth of HL-60 was significantly inhibited, showing a rational way to develop an effective molecular anti-cancer agent.
Cell Line ; Computer Simulation ; Genes, myb ; Liposomes ; Oligonucleotides, Antisense* ; RNA, Messenger