2.Pathophysiologic Mechanism of the Cardiac Failure in the Subacute Diffuse Myocarditis associated with Granulomatous Myocarditis.
Korean Journal of Legal Medicine 1997;21(1):87-96
The heart, 500g in weight, with subacute myocarditis associated with granulomatous myocarditis may be a good model for the study on the pathophysiologic mechanism of cardiac failure. Furthermore, the clinical data of this case is enough to clarify his all clinical course from admission to death due to cardiac failure. So, we analyzed the clinical data, histologic findings, and morphometric pattern of histologically intact myocardial cells and inflammatory reaction to investigate the pathophysiologic mechanism of the cardiac failure. The results were summarized as follows. 1. Clinically, the heart showed cardiac failure of diastolic phase and abnormal conduction system related to sudden cardiac death. However, it might be adapted to the relatively stable wital signs due to pericardial positive pressure by slowlyprogressed pericardial effusion. 2. The distribution pattern of area of intact myocardial cell area and inflammtion reaction showed relatively even spread of inflammatory reaction and extremely decreased area of myocardial cells to about 21% of total heart. So, its contractility might be decreased below to the 21% of the normal cardiac contractility. 3. The mechanism of the cardiac failure in myocarditis may be sudden inflammatory involvement of conduction system and/or extremely decreased myocardial cell volume due to inflammatory destruction. 4. Morphometric analysis may be a useful objective method to grading the severity of old and recent form of myocarditis. From the above results, the cardiac failure of myocarditis is influenced by the adaptability at the inflammatory abnormality of the conduction system, contractility of injured myocardial cells, and compensation activity of pericardial effusion.
Cell Size
;
Compensation and Redress
;
Death, Sudden, Cardiac
;
Heart
;
Heart Failure*
;
Myocarditis*
;
Pericardial Effusion
3.LOWER LIP RECONSTRUCTION WITH BARREL-SHAPED EXCISION.
Taik Jong LEE ; Tae Joon KIM ; Jong Pil PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(6):1425-1430
No abstract available.
Lip*
4.Calcification and Aneurysms of Coronary Artery without Atherosclerosis in Young Adult.
Ji Shin LEE ; Young Jik LEE ; Jong Tae PARK
Korean Journal of Legal Medicine 1997;21(1):105-112
Coronary artery calcification(CAC) is found frequently in the atheromatous plaques CAC is known to have increased frequency above 40 years. CAC without evidence of atherosclerosis in young adults is quite rare, however, CAC combined with aneurysms in young adults have been infrequently reported in patients with a past history of a Kawasaki disease in child. We report an autopsy case showing CAC and aneurysm in the absence of macroscopically identified atherosclerotic lesions in a healthy 23-year-old man. The autopsy examination revealed aneurysmal dilatation of the right coronary artery which was connected with calcified lesion. A calcified lesion of the left anterior descending coronary artery was aslo noted. Microscopically, aneurysmal wall was non-specific except for hyalinized wall and foci of calcification. A striking histologic finding of calcified mass was ring calcification along the wall of the coronary artery. Antecedent Kawasaki disease in the past was suggestive as other reports.
Aneurysm*
;
Atherosclerosis*
;
Autopsy
;
Child
;
Coronary Vessels*
;
Dilatation
;
Humans
;
Hyalin
;
Mucocutaneous Lymph Node Syndrome
;
Plaque, Atherosclerotic
;
Strikes, Employee
;
Young Adult*
5.A Study for Hemodynamic Mechanism of Myocardial Infarction following Aortic Dissection.
Young Jik LEE ; Ji Shin LEE ; Jong Tae PARK
Korean Journal of Legal Medicine 1997;21(1):97-104
Aortic dissection may be considered the result of a discrepancy between the strength of the aortic wall and the intramural pressure. And factors that predispose to aortic dissection may include systemic hypertension, cystic medial necrosis, Marfan's syndrome, atherosclerosis, disease of aortic valve, pregnancy, giant cell arteritis, hyperthyrosis, disease of aortic valve, pregnancy, giant cell arteritis, hyperthyroidism, and blunt chest trauma. A few of aortic dissection may extend retrograde toward the aortic valve and involve the coronary arteries. Coronary artery occlusions due to mural dissection are an uncommon but well documented cause of myocardial infarction. Although rare, extramural hematoma compressing the coronary artery is another cause of myocardial infarction. At autopsy of 43 years old male who had no critical external wound, pericardial sac was distended and contained 400ml of dark red and clotted blood. Examination of the aorta revealed only minute atherosclerosis, intact aortic valve, and patent coronary ostia. 0.5cm sized aortic rupture was noted at the 3.5cm distal to the aortic valve. DeBakey type II aortic dissection was found to involve the ascending aorta and brachiocephalic trunk. Three intimal tears were 1.5cm, 8cm. 11.5cm distal to the aortic valve and two false lumens which had intact area between them extended 3.5cm distal to the third intimal tear and proximally in a retrograde fashion to the aortic root. Microscopically, sections of aorta showed relatively intact arrangement of smooth muscle and elastic fibers, except mild vascular ectasia and scattered several foci of the small sized aggregation of foamy histiocytes, and there was no evidence of cystic medial degeneration in aorta. Sections of both coronary arteries did not show mural dissection or atherosclerosis. Sections of right atrium and sinus node showed inflammatory reaction, extensive replacement of myocardium by active fibrous tissue consistent with infarction. There was no histologic evidence of myocardial infarction in the walls of other chambers or septum of the heart. We believe that extramural compression of the artery to sinus m\node by the dissecting hematoma was the cause of myocardial infarction involving the right atrium and the sinus node.
Adult
;
Aorta
;
Aortic Rupture
;
Aortic Valve
;
Arteries
;
Atherosclerosis
;
Autopsy
;
Brachiocephalic Trunk
;
Coronary Vessels
;
Dilatation, Pathologic
;
Elastic Tissue
;
Giant Cell Arteritis
;
Heart
;
Heart Atria
;
Hematoma
;
Hemodynamics*
;
Histiocytes
;
Humans
;
Hypertension
;
Hyperthyroidism
;
Infarction
;
Male
;
Marfan Syndrome
;
Muscle, Smooth
;
Myocardial Infarction*
;
Myocardium
;
Necrosis
;
Pregnancy
;
Sinoatrial Node
;
Thorax
;
Wounds and Injuries
6.Significance of the preoperative examinations in predicting the defect size of ventricular septal defect.
Keun KIM ; Bong Hyun CHANG ; Jong Tae LEE ; Kyu Tae KIM ; Sang Bum LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(3):289-295
No abstract available.
Heart Septal Defects, Ventricular*
7.Percutaneous catheter drainage of intraabdominal abscesses and fluid
Jong Tae LEE ; Tae Hee KWON ; Hyung Sik YOO ; Jung Ho SUH ; Young Ho LEE
Journal of the Korean Radiological Society 1986;22(5):661-671
Percutaneous catheter drainage has been reported to bean effective method in the management of selectedpatients with abscess and fluid collection. Its high sucess rate and relatively low complications make theprocedure an alternative to surgery in the individual cases. During past two years percutaneous catheter dainagein 25 patients with intraabdominal abscesses and fluid collection was performed at the Department of Radiology,Yonsei Universtiy College of medicine. Here the technique and auathor's results were summarized; 1. The total 25patients who had percutaneous catheter drainage are 10 liver abscesses, 3 subphrenic, one subhepatic, 4 renal andperirenal, 2 pelvic, one psoas, one anterior pararenal fluid from acute pancreatitis, one pancreas pseudocyst and2 malignant tumor necrosis. 2. The modified Seldinger technique used for all cases of abscess and fluid draingeunder guidence of ultrasound scan. The used catheters were 10F. Pigtail and 14F. Malecot (Cook c/o) catheters. 3.The abscesses and fluid of 17 patients among 25 were cured by the percutaneous catheter drainage and 4 patientswere clinically improved. The catheter drainage was failed in 2 patients and 3 complications were developed. 4.The success rate of this procefure was 91.3%, failure rate was 8.7% and complication rate was 12%.
Abscess
;
Catheters
;
Drainage
;
Humans
;
Liver Abscess
;
Methods
;
Necrosis
;
Pancreas
;
Pancreatitis
;
Ultrasonography
8.The clinical characteristics of insomnia in general hospital inpatients.
Jong Gook LEE ; Chang Hwan HAN ; Tae Hyuk YOO
Journal of Korean Neuropsychiatric Association 1991;30(1):125-134
No abstract available.
Hospitals, General*
;
Humans
;
Inpatients*
;
Sleep Initiation and Maintenance Disorders*
9.Depression of highschool senior students in Seoul.
Min Chang LEE ; Mi Kyung OH ; Jong Tae CHOI
Journal of the Korean Academy of Family Medicine 1992;13(12):927-934
No abstract available.
Depression*
;
Humans
;
Seoul*
10.Cryopathic Hemolytic Anemia: A case report.
Jong Weon CHOI ; Jin Tae SUH ; Mi Kyung LEE
Korean Journal of Blood Transfusion 1995;6(2):177-184
The cryopathic hemolytic anemia is an autoimmune hemolytic anemia induced by cold antibody. Authors report a case of cryopathic hemolytic anemia confirmed by immunohematologic examination. A 22-year-old man was admitted at Kyung Hee Medical Center in March, 1994, with a past history of Kleinerfelter's syndrome and complained jaundice as well as dizziness. Direct antiglobulin test using polyvalent and anti-C3d monovalent antisera was positive, but was negative against anti-IgG, anti-IgA, and anti-IgM monovalent antisera. Cold agglutinin titer was as high as 1:1024 at 4 degrees C and anti-I specificity was confirmed by using cord bloods. The patient was not improved despite transfusion of washed red cells and administration of prednisolone, and on 16th day of hospitalization he manifested sudden episode of headache and loss of conscioussness, soon followed by death.
Anemia, Hemolytic*
;
Anemia, Hemolytic, Autoimmune
;
Coombs Test
;
Dizziness
;
Fetal Blood
;
Headache
;
Hospitalization
;
Humans
;
Immune Sera
;
Jaundice
;
Prednisolone
;
Sensitivity and Specificity
;
Young Adult