BACKGROUND: The reference list is an important part of a scientific papers. To be useful it must be accurate OBJECTIVE: The purpose of this study was to evaluate quotation accuracy in the Korean Journal of Dermatology and the Annals of Dermatology. METHODS: We randomly selected 35 references from Korean Journal of Dermatology and 35 references from Annals of Dermatology and checked them against the original articles. RESULTS: The overall rate of quotation error was 32.9%, respectively 40% in the Annals of Dermatology and 25.7% in the Korean Journal of Dermatology. CONCLUSION: This study shows that the rate of quotation errors is unacceptably high in the Korean Journal of Dermatology and the Annals of Dermatology, which significantly diminishes the value of the information of its source.
Dermatology*

The antihypertensive effect of verapamil, a calcium channel blocker, was studied in 12 cases of essential hypertension (mean age 49, range 24-64). After 6 weeks administration (80-160mg t.i.d.), the following results were obtained : 1) Before medication, average systolic and diastolic blood pressure was 176.3/108.6mmHg. After completion of therapy, blood presure fell significantly down to 154.8/94.2mmHg (p<0.01). 2) Heart rate decreased slightly from average 74.3 per minute prior to medication to 69.3 per minute at the end of study (p<0.01). 3) Side effects, among which constipation was most common, were mild and did not compel any patient to diacontinue therapy. In conclusion, verapamil seems to be a safe and effective first-line drug for hypertension along with diuretics or beta blockers.
Blood Pressure ; Calcium Channels ; Constipation ; Diuretics ; Heart Rate ; Humans ; Hypertension ; Verapamil*

No abstract available.
Free Tissue Flaps* ; Upper Extremity*

BACKGROUND: Statistical errors have been noted in a large percentage of articles appearing in medical journals. Their incidence in the Annals of Dermatology and the Korean Journal of Dermatology, however, has not been studied. OBJECTIVE: The purpose of this study was to evaluate the accuracy of statistical methods in the Annals of Dermatology and the Korean Journal of Dermatology. METHOD: Original papers using the t test in the Annals of Dermatology(AD) and in the Korean Journal of Dermatology(KJD) from January 1990 to July 1994 were analyzed for correctness of statistical methods. RESULTS: Of the 376 original papers in the period considered, 78(20.7%) presented t tests and 43(55.1%) of these also contained some errors. Of the 9 papers from the Annals of Dermatology, 4(44.4%) included at least one error. Of the 69 papers from the Korean Journal of Dermatology, 39(56.5%) included at least one error. CONCLUSION: Misuse of statistical methodology may not be uncommon in the two Korean Dermatology journals, and it would be prudent to give more attention to statistical methodology.
Dermatology* ; Incidence ; Methods

BACKGROUND: The reference list is an important part of a scientific article. To be useful it must be accurate. OBJECTIVE: The purpose of this study was to evaluate the accuracy of reference citations in the Korean Journal of Dermatology and the Annals of Dermatology. METHODS: We randomly selected 200 references (100 references from Korean language journals and 100 references from foreign language journals) from the Korean Journal of Dermatology and 100 references from the Annals of Dermatology and checked them against the .original articles. RESULTS: The overall rate of citation error was 32%, and errors in the title and author names of the citation were common, each occurring in about two fifths of the citation errors. CONCLUSION: This study shows that the rate of citation errors is unacceptably high in the Korean Journal of Dermatology and the Annals of Dermatology, which significantly diminishes the value of the reference list.
Dermatology*

No abstract available.
Fingers*

To assess the immunological function of toluene exposed group, the proportions of T lymphocyte, B lymphocyte, CD 4 cell, CD 8 cell, the ratio of CD4 to CD8 (CD4/CD8) in peripheral blood were measured on twenty-one toluene exposed workers and twelve healthy workers who did not have previous history of toluene exposure. In addition, to evaluate the present status of toluene exposure, urinary hippuric acid concenturations were measured in exposed group. The mean concenturation of urinary hippuric acid was 2.84 g/creatinine g in exposed group. The proportions of T lymphocyte, B lymphocyte, CD8 cell and CD4/CD8 of exposed group were slightly lower than non-exposed group except the proportion of CD4 cell which was similar in both groups. But these differences were not statistically different in both groups. The proportions of T lymphocyte and CD4 cell were significantly correlated with the length of duration in exposed group (P<0.05)
Lymphocytes ; Occupations* ; Toluene*

Familial benign pemphigus(Hailey-Hailey disease) is a rare hereditary dermatosis that begins in the 2nd or 3rd decade of life. The skin lesion is characterized by a localized, recurrent eruption of small vesicles on an erythematous base. During its course there are remissions and exacerbations. It seldom begins in early childhood or after the age of 50. The main treatment modalities are conservative ones. A 59-year-old woman with familial benign chronic pemphigus presented with a 10 year history of generalized pruritic recurrent skin lesions on her neck, axilla, inguinal, antecubital, and trunk area. Physical examination showed moist, macerated, fissured and scaly patches on an erythematous base in the axillae, groins, neck, antecubital, and trunk. A biopsy specimen showed extensive suprabasal separation containing acantholytic cells.
Axilla ; Biopsy ; Female ; Groin ; Humans ; Middle Aged ; Neck ; Pemphigus* ; Pemphigus, Benign Familial ; Physical Examination ; Skin ; Skin Diseases

No abstract available.
Cesarean Section* ; Female ; Pregnancy

It is generally recognized that several chemical mediators are involved in tbe pathogenesis of sunbum; however, the exact mechanism is still to he resolved. Recently, prostaglandin has been found to be one of the inflammatory mediators in sunbum, particularly in the delayed erythema response and several investigators have shown that the nonsteroidal antiinflammatory drugs inhibit the in vivo synthesis of prostaglandin. On the assumption that the nonsteroidal antiinflammatory drugs might exert a beneficial effect on the sunbum through the antiprostaglandin effect, several authors have reported the effect of indomethacin on sunbum. This study was undertaken to evaluate the effect of topical indomethacin on the delayed erythema response induced by artificial sunlamp and sunlight by clinical and histopathological examination. Indomethacin(2. 5% ointment, 2. 5% solution, 5% solution) was applied immediately after 3 MED irradiation of artificial sunlamp to the shaved back skin of 6 healthy albino guinea pigs weighing 550-850gm and 9 human volunteers and the delayed erythema response was observed at 2, 4, 6, 12, 24 and 48 hours after irradiation respectively. Punch biopsies of the skin were performed on 6 guinea pigs at 6, 12, 24 a.nd 48 hours after irradiation and the histologic changes were observed. Four human volunters were exposed t,o 3 MED of sunlight and indomethacin preparations were applied immediately after irradiation. The delayed erythema response was observed at 2, 4, 6, 12, 24 and 48 hours postirradiation and in one volunteer, the skin was biopsied at 24 hour for histologi.c evaluation. The results were as follows: 1. Topical indomethacin in ointment or solution forms delayed and decreased the appearance and degree of erythema induced by sunlight and artificial sunlamp in both human and animal subjects. 2. Histologically, the number of sunbum cells at 24 hour in the epidermis of one human volunteer was decreased on indomethacin applied sites. The dermis showe6 no difference in histologic changes between control and indomethacin sitea. In animal study, however, no detectable difference in epidermal or dermal changes was observed between control and indomethacin applied sites. The autors confirmed that topical indometha,cin was effective in delaying and blanching of the delayed erythema of sunbum in guinea pigs as well as in human volunteers, though there was no difference in histologic changes between indomethacin and control sites in guinea pigs. The mechanism involvel on this aspect is remained to be resolved.
Animals ; Biopsy ; Dermis ; Epidermis ; Erythema ; Guinea Pigs ; Healthy Volunteers ; Humans ; Indomethacin* ; Research Personnel ; Skin ; Sunburn* ; Sunlight ; Volunteers