Confluent and reticulated papillomatosis(CRP) is a rare dermatosis. The lesions are hyperkeratotic, verrucous papules and plaques, resulting in a confluence of lesions centrally and a reticulated pattern at the periphery. It is more common in women and during puberty. The histopathological findings show papillomatosis, hyperkeratosis and a sparse superficial perivascular lymphocytic infiltrate. We report a case of CRP that responded to oral etretinate in an 18-year-old man.
Acitretin* ; Adolescent ; Etretinate* ; Female ; Humans ; Papilloma* ; Puberty ; Skin Diseases

Acquired tufted angioma is a benign, progressive vascular lesion that has a distinctive histopathologic appearance. We report a 31-year-old man with acquireed tufted angioma. Several reddish papules and plaque were present on the neck. The lesion had been present for 6 months. They had enlarged slowly, and were slightly tender. Histopathologic examination of the biopsy specimen showed round to ovoid cellular tufts of capillaries, most prominent in the middle to lower dermis.
Adult ; Biopsy ; Capillaries ; Dermis ; Hemangioma* ; Humans ; Neck

No abstract available.
Family Practice* ; Follow-Up Studies* ; Humans ; Internship and Residency*

Since the discovery of U. urealyticum in human. the etiologic role of this microbe to urogenital tract infection has been investigated. U. urealyticum is one of the etiologic agents for such infections of human urogenital tract as nongonococcal urethritis. prostatitis. cystitis. infertility. interauterine infection, in which standard bacteriologic investigation had failed to indicate bacterial infection. We studied the occurrence of U. urealyticum in urogenital tract of persons in the district of Pusan. From March, 1990 to June. 1990, 290 heterosexual patients and 102 normal control were cultured for U. urealyticum. The results were as follows : l. Overall incidence of this organism was 19.3%, 32.2% from urethral swab and 10.5% from urine, which was lower than that of control group. 2. The incidence of this organism in Females (32.7%) was generally higher than that in males ( 16.6%). 3. This microbe was well detected in middle age person. 4. This microbe was higher detected in specimen from urethral swab (32.2%) than urine (10.5%). 5. The isolation ratio in local private clinics was lower than that in Kosin medical center. 6. Erythromycin had the best sensitivity against U. urealyticum followed by streptomycin. But tetracycline and oxytetacycline were highly resistant to this organism.
Bacterial Infections ; Busan ; Cystitis ; Erythromycin ; Female ; Heterosexuality ; Humans ; Incidence ; Infertility ; Male ; Middle Aged ; Mycoplasma ; Prostatitis ; Streptomycin ; Tetracycline ; Ureaplasma urealyticum* ; Ureaplasma* ; Urethritis

Opacification of the gallbladder after parenteral administration of contrast material usually indicates diminished renal function but can occur with normal renal function. The authors recently experienced 13 cases of such vicarious excretion of contrast media. Among 13 patients. 9 patients had renal disease unilateral ureteral stone(n=3), staghorn calculi(n=2), acute renal failure from sepsis(n=1), renal contusion(n=2) and unilateral renal artery involvement by dissecting aortic aneurysm(n=1). Of these 9 patients, 3 patients showed abnormal serum creatinine levels at the time of presentation or shortly thereafter. In 6 patients, injection of a large amount of contrast media was possibly the additional cause of vicarius excretion. There was no detectable cause in the remaining 4 patients. Heterotopic excretion of contrast media is clearly a complex phenomenon, the reason for which it is difficult to establish with certainty in each individual case. Anyhow, vicarius excretion of contrast media occurs more frequently than previously thought, and it can occur not only with abnormal renal function but with normal function also.
Acute Kidney Injury ; Contrast Media ; Creatinine ; Gallbladder* ; Humans ; Renal Artery ; Ureter

No abstract available.
Drug Therapy* ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

BACKGROUND: The histogenesis of acquired melanocytic nevi is still a matter of debate. One considers that nevus cells originate from epidermal melanocytes and the other postulates that nevus cells are of both neural and melanocytic origin. OBJECTIVE: To clarify this controversy, investigation of the growth dynamics and tissue homeostasis of nevi is needed. METHODS: We compared expressions for PCNA and bcl-2 in 12 intradermal nevi and 8 compound nevi by immunohistochemical staining. RESULTS: The results are summarizid as follows: 1. bcl-2 : Both intradermal and compound nevi exhibited strong perinuclear and cytoplasmic staining. There was diminution of staining with progressive descent into the dermis. 2. PCNA : The mean rate of PCNA-positive nevus cells was higher in compound nevi than in intradermal nevi. CONCLUSION: The findings of our study shows considerable differences between intradermal nevi and compound nevi in expressions for PCNA and bcl-2.
Cytoplasm ; Dermis ; Homeostasis ; Melanocytes ; Nevus ; Nevus, Intradermal ; Nevus, Pigmented* ; Proliferating Cell Nuclear Antigen*

BACKGROUND: The causative organisms and clinical characteristics of dermatophytoses are altered by various factors such as social environmental change and geographic distribution. OBJECTIVE: The purpose of this research is to investigate the changes and recent clinical and mycological features of dermatophytoses in the Chungcheongnam-do province. METHODS: We performed clinical and mycological studies on 387 cases of dermatophytoses among outpatients of Dermatologic clinic of Soonchunhyang University Cheonan Hospital for 5 years, from January 2008 to December 2012. RESULTS: 1. The age distribution showed patients in their 50s to be the most common. The ratio of male to female was 1.07:1. 2. The seasonal prevalence of dermatophytoses was highest in the summer, but the incidence of tinea capitis was highest in the winter season. 3. The positive rate of KOH examination was 95.1% and that of culture was 58.9%. 4. Trichophyton(T.) rubrum was most prevalent dermatophyte (71.1%), followed by Microsporum(M.) canis (9.2%), T. mentagrophytes (7.9%). CONCLUSION: Compared with previous study, the incidence of T. rubrum infection is rising and in recent years the prevalence of M. canis infection has markedly increased. The rest of causative organisms' proportion is increasing and diversification is observed.
Age Distribution ; Arthrodermataceae ; Female ; Humans ; Incidence ; Male ; Outpatients ; Prevalence ; Seasons ; Social Environment ; Tinea ; Tinea Capitis

BACKGROUND/AIMS: It has been reported that the difference in the hepatitis C virus (HCV) genotype due to genetic heterogeneity of HCV influence the clinical features, prognosis of HCV associated liver disease and response to interferon therapy. Prevalence of different genotypes of HCV may also vary between geographic areas. The aim of this study was to examine the relationship between the response to interferon alpha (IFN-a) therapy and HCV genotypes in patients with chronic HCV infection in Taegu and its environs. METHODS: One hundred seventy six patients known to be HCV antibody and HCV-NA positive were evaluated for HCV genotypes by restriction fragment length polymorphism. Among patients who had elevated ALT levels, 67 patients have been investigated for the role of the HCV genotype on disease outcome and the response of IFN-a therapy. RESULTS: Genotype 1b were found in 59.0% of patients (103/176), genotype 2a in 37.5% (66/176). The mode of transmission of HCV infection was guessed as transfusion in genotype 1b, but as parenteral infection in genotype 2a. According to their response to IFN-a therapy, 73 patients were divided into three groups, complete response, 18 (60%) of 30 patients with genotype 2a and 21 (48.8%) of 43 patients with genotype 1b: partial response, 5 (16.7%) of 30 patients with genotype 2a and 7 (16.2%) of 43 patients with genotype 1b: no response, 7 (23.3%) of 30 patients with genotype 2a and 15 (34.9%) of 43 patients with genotype 1b. Good response to IFN-a therapy was observed among patients group showing normal platelet count in patients with genotype 1b and normal GGT in patients with genotype 2a. CONCLUSIONS: The most frequently identified genotype was genotype 1b in Taegu and its environs, followed by genotype 2a. The HCV genotype was not a reliable predictor of response to IFN-a therapy. When a standardized regimen of IFN-a was administered, pretreatment serum platelet counts and GGT level seem to be useful predictor of IFN-a therapy in HCV infection. Further investigations are required in order to establish a correlation between viral factors and therapeutic responses.
Daegu* ; Genetic Heterogeneity ; Genotype* ; Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Humans ; Interferon-alpha ; Interferons ; Liver Diseases ; Platelet Count ; Polymorphism, Restriction Fragment Length ; Prevalence ; Prognosis

No abstract available.
Aged* ; Humans