1.Clinical significance of the expression oncosuppressor gene proteins and epidermal growth factor receptor in squamous cell carcinomas of the larynx.
Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):990-1004
No abstract available.
Epidermal Growth Factor*
;
Larynx*
;
Proteins*
;
Receptor, Epidermal Growth Factor*
2.No title available in English.
Jung Soo PARK ; Woong Yoon JEONG ; Jong Ho YOON ; Jong Joo JEONG ; Eun Kyung KIM
Korean Journal of Endocrine Surgery 2003;3(1):69-73
No abstract available.
3.Changes of intercellular adhesion molecule expression and cytogenetic abnormalities during the differentiation process in human neuroblastoma cell lines.
Jong Jae KIM ; Yoon Jung CHOI ; Chul Woo KIM
Journal of the Korean Cancer Association 1993;25(4):563-571
No abstract available.
Cell Line*
;
Chromosome Aberrations*
;
Cytogenetics*
;
Humans*
;
Neuroblastoma*
4.The effects of imipramine on the lymphocyte beta-adrenergic receptor binding and plasma level of 3-methoxy-4-hydroxyphenylglycol(MHPG) in rats.
Jong Inn WOO ; Chang Yoon KIM ; Jung Hie LEE
Journal of Korean Neuropsychiatric Association 1993;32(6):1036-1048
No abstract available.
Animals
;
Imipramine*
;
Lymphocytes*
;
Plasma*
;
Rats*
5.Intracerebral Hemorrhage in Eclampsia : Two Cases Report.
Dong Yoon NAM ; Soo Jung YOO ; Jong In KIM
Korean Journal of Obstetrics and Gynecology 2000;43(9):1679-1683
No abstract available.
Cerebral Hemorrhage*
;
Eclampsia*
;
Female
;
Pregnancy
6.LPS-induced Chemokine Gene Expression in Mesangial Cell.
Hark RIM ; Soo Jung YOON ; Jong Wook PARK
Korean Journal of Nephrology 1999;18(6):847-855
This study was designed to investigate the mole- cular mechanism of chemokine induction by lipopoly-saccharide(LPS) of E. coli. Chemokine gene expression was evaluated by the reverse transcriptase-polymerase chain reaction(RT-PCR) assay using RNAs isolated either from kidneys of LPS-injected inice or from the mesangial cells stimulated with LPS, IFN-r or TNF-a. LPS was shown to induce interferon gamma(IFN- 7 ) inducible protein 10 (IP-10) and monokine induced by interferon gamma (MIG) in kidney. IP-10 gene expression was induced by LPS and IFN-r, but MIG gene expression was induced by IFN-r in mesangial cell. Chemokines induced by LPS increased splenocyte migration. Sodium salicylate, wortmanin and piperazine blocked LPS mediated chemokine induction suggesting the activation of nuclear factor-a B pathway. It is concluded from this study that mesangial cells are the target of LPS in the renal failure resulting from the systemic infections. LPS induces chemokines directly and/or indirectly in the mesan- gial cells, and these chemokines may associated with renal inflammation.
Chemokines
;
Gene Expression*
;
Inflammation
;
Interferons
;
Kidney
;
Mesangial Cells*
;
Renal Insufficiency
;
RNA
;
Sodium Salicylate
7.The effect of adjuvant CMF(cyclophosphamide, methotrexate, 5-FU) chemotherapy of breast cancer.
Joon PARK ; Jung Han YOON ; Young Jong JEGAL
Journal of the Korean Cancer Association 1993;25(6):928-934
No abstract available.
Breast Neoplasms*
;
Breast*
;
Drug Therapy*
;
Methotrexate*
8.Induction of Dendritic Cell and Cytokine Gene Expression by In situ Delivery of Flt3 Ligand Plasmid.
Jong Wook PARK ; Soo Jung YOON ; Byung Kil CHOE
Korean Journal of Immunology 1998;20(2):179-186
Dendritic cell (DC)s are protessional antigen presenting cells and they have been used for antitumor immunotherapy or cell vaccines. However therapy using DC is restricted because the number of DC available from tissue is very low. Flt3 ligand (FL) has been known as a hematopoietic growth factor that increases proliferation of hematopoietic stem cells and progenitor cells, and recently it showed inducibility of dendritic cell (DC)s and signiticant antitumor effects in vivo. Thus FL will be frequently used for DC induction and antitumor immunotherapy in future. Here we constructed FL plasmid and studied its in vivo effect. FL plasmids were made by cloning of partial FL cDNA into pcDNA3 plasmid, and gene expression and protein producibility of FL plasmid were confirmed in Renca cells transfected with FL plasmid. Mice were injected with FL plasmid (100ug/mouse) three times and 20 days later mouse spleens were harvested for staining and RT-PCR. There were lots of blastogenic cells in the spleen of mice treated with FL plasmid. FL plasmid also induced DEC205, IL-12 and GM-CSF gene expression in mouse splenocyte. All these data suggest FL plasmid may be used for induction of DC and antitumor therapy as DNA adjuvant.
Mice
;
Animals
9.Experimental study of interstitial Nd:YAG laser hyperthermia on rabbit tongue mucosa.
Youn Woo NAM ; Kwang Yoon JUNG ; Jong Ouck CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):977-989
No abstract available.
Fever*
;
Mucous Membrane*
;
Tongue*
10.Primary malignant tumors of the ethmoid sinus.
Seung Ho LEE ; Jong Ouck CHOI ; Kwang Yoon JUNG
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):920-924
No abstract available.
Ethmoid Sinus*
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