No abstract available.
Carcinoma, Renal Cell* ; Neoplasm Metastasis*

No abstract available.
Carcinoma, Renal Cell* ; Neoplasm Metastasis*

No abstract available.
Child* ; Humans ; Syringoma* ; Vulva

Electrocautery of nasal septum is a very common treatment of epistaxis in Otorhinolaryngology. However, serious complications of electrocautery are rare. We encountered a 52-year-old female patient who presented with nosebleeds. A definite focus of bleeding was identified by nasal endoscopy, thus electrocautery by bipolar diathermy was performed in the area of Kisselbach's plexus of nasal septum. There were no abnormal findings in the nasal septum during the three weeks of outpatient visit. However, the patient noticed a depression near the tip of her nose 12 weeks later. Saddle nose deformity after electrocautery has not yet reported in the literature. Therefore, we present this case with a brief review of literature.
Congenital Abnormalities* ; Depression ; Diathermy ; Electrocoagulation* ; Endoscopy ; Epistaxis ; Female ; Hemorrhage ; Humans ; Middle Aged ; Nasal Septum* ; Nose* ; Otolaryngology ; Outpatients

Objectives: Despite the popularization of technology and the high penetration rate of smartphones and mobile devices, differences exist in the accessibility, utilization capabilities, and quality of technology depending on users’ characteristics. Since these discrepancies can threaten health information equity, popularization of medical information is essential. This review article examines domestic and international cases of popularization of medical information, and discusses the related issues, expectations, and practical measures to achieve the popularization of medical information. Methods: In this study, medical information was categorized as Electronic Health Records/Electronic Medical Records (EHR/EMRs; hospital-driven medical information), personal health records (PHRs; user-driven medical information), and patient-generated health data (PGHD; user-generated medical information [outside hospitals]). This article reviewed the domestic and international use status, acceptance rates, and use cases for each type of medical information. Issues and expectations about policies and cases related to the popularization of medical information were also described, and finally, practical measures to accomplish the popularization of medical information were discussed. Results: To achieve the popularization of medical information, the following measures should be considered: engaging health consumers to participate in the early stages of information production, cultivating digital literacy, producing easy-to-use and interesting medical content, visualizing health information, and creating a medical thesaurus. Conclusions Healthcare providers should make regular efforts to popularize medical information. The popularization of medical information is an essential process to achieve health equity and digital health equity.

Objectives: Despite the popularization of technology and the high penetration rate of smartphones and mobile devices, differences exist in the accessibility, utilization capabilities, and quality of technology depending on users’ characteristics. Since these discrepancies can threaten health information equity, popularization of medical information is essential. This review article examines domestic and international cases of popularization of medical information, and discusses the related issues, expectations, and practical measures to achieve the popularization of medical information. Methods: In this study, medical information was categorized as Electronic Health Records/Electronic Medical Records (EHR/EMRs; hospital-driven medical information), personal health records (PHRs; user-driven medical information), and patient-generated health data (PGHD; user-generated medical information [outside hospitals]). This article reviewed the domestic and international use status, acceptance rates, and use cases for each type of medical information. Issues and expectations about policies and cases related to the popularization of medical information were also described, and finally, practical measures to accomplish the popularization of medical information were discussed. Results: To achieve the popularization of medical information, the following measures should be considered: engaging health consumers to participate in the early stages of information production, cultivating digital literacy, producing easy-to-use and interesting medical content, visualizing health information, and creating a medical thesaurus. Conclusions Healthcare providers should make regular efforts to popularize medical information. The popularization of medical information is an essential process to achieve health equity and digital health equity.

BACKGROUND AND OBJECTIVES: Many studies report changes in the expressions of nasal secretory proteins which play important roles in the evaluation of sinonasal mucosal status. The biomarkers in nasal secretions provide valuable information on pathophysiological status of the rhinosinusitis. We have monitored the level and ratio of nasal secretion markers, especially secretory IgA (sIgA) and lactoferrin as markers of sinonasal submucosal glands to evaluate mucosal status for chronic sinonasal diseases and allergic rhinitis. SUBJECTS AND METHOD: Samples were obtained with the filter paper absorption method from 20 normal healthy controls (Group I), 20 patients with chronic rhinosinusitis (Group II), 20 patients with allergic rhinitis (Group III), 20 normalized persons of chronic rhinosinusitis patients treated with antibiotics, previously (Group IV). We estimated concentrations of sIgA and lactoferrin determined by enzyme-linked immunosorbent assay method. RESULTS: The concentration of sIgA and lactoferrin in nasal secretion showed a significant difference between the control group and other groups (p<0.05). The sIgA/lactoferrin ratio was more highly significant in the normal group and normalized in chronic rhinosinusitis patients treated with antibiotics (Group IV) than other groups (p<0.05). CONCLUSION: In this study, sIgA and lactoferrin are useful secretion markers and the levels of sIgA, lactoferrin and sIgA/lactoferrin ratios in nasal secretions seem to be very useful parameters for monitoring and assessing the conditions of the sinonasal mucosal diseases.
Absorption ; Anti-Bacterial Agents ; Biomarkers ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunoglobulin A, Secretory ; Lactoferrin ; Rhinitis

BACKGROUND AND OBJECTIVES: The histologic difference of the traumatic nasal septal cartilage from that of non-traumatic has not been extensively studied. The aim of this study was to identify histologic difference in the nasal septal cartilage between traumatic and non-traumatic nasal septal deviation and to find its implication for surgical intervention. SUBJECTS AND METHOD: Nasal septal cartilage was obtained from 23 patients who had undergone septoplasty or septorhinoplasty for the nasal septal deviation. The septal cartilage without trauma (7 patients, Group I) and with the history of the trauma at the age under 10-15 years old (8 patients, Group II), and over 25 years old (8 patients, Group III) between May 2003 to February 2005 were included in this study. An approximately 1 x 1 cm sized piece of the septal cartilage was harvested from the site deviated the most. The histologic difference of the septal cartilage by hematoxylineosin staining under a light microscope was performed. RESULTS: The chondrocyte densities were significantly higher in the convex side than in the concave side of the septal cartilage in Group I, II, III. Especially, the increased chondrocyte ratio (convex/concave) were more evident in the septal cartilage traumatized at the age of 10 to 15 years, and the cartilage plate was thicker than the other groups (p<0.001). Also, dystrophic changes of the chondrocytes as representing the chondrocyte differentiation and chondroblast ratio (convex/concave) were significantly higher in the group II than in the other groups (p<0.005). CONCLUSION: This study demonstrated that age dependent changes in septal cartilage with nasal trauma showed distinctive histologic characteristics. We suggest that these observations will help determine surgical treatment modality for cases of nasal septal deviations with and without trauma.
Adult ; Cartilage* ; Chondrocytes ; Humans

The empty sella syndrome is defined as the intrasella herniation of the chiasmal cistern resulting from a congenitally incompetent diaphragma sellae. In idiopathic or primary empty sella syndrome, sella remodelling occurs as a result of an anatomical variation in the diaphragma sella. The secondary empty sella syndrome occurs following surgery or irradiation of an intrasellar lesion. Empty sella syndrome is known to be rarely associated with Cerebrospinal fluid (CSF) rhinorrhea. We experienced a case of secondary empty sella symdrome with CSF rhinorrhea in a 56-year old female who complained of persistent rhinorrhea through the roof of the sphenoid sinus after brain surgery due to meningioma. The CSF rhinorrhea was treated successfully with transseptal trans-sphenoidal approach.
Brain ; Cerebrospinal Fluid Rhinorrhea* ; Cerebrospinal Fluid* ; Empty Sella Syndrome* ; Female ; Humans ; Meningioma ; Middle Aged ; Sphenoid Sinus