BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris ; Age Distribution ; Child ; Daegu ; Dermatitis ; Dermatitis, Contact ; Female ; Granuloma Annulare ; Humans ; Korea ; Male ; Outpatients ; Rosacea ; Seasons ; Skin Diseases ; Tinea*

BACKGROUND: Tinea faciale usually has been classified as tinea corgoris. Recently it has often been classified as a seperate disease recently because of its various clinicel pesentations. OBJECTIVE: Our purpose was to evaluate the clinical characteristics and mycological findings of tinea faciale, METHODS: Clinieal and mycological study was done with 42 eases of tinea faciale among out-patients examined for eight years from January 1985 to December 1992 at Yeungnam University Hospital, Taegu, Korea. RESULTS & CONCLUSION: 1. The average of annual distribution of patients was five and there a as no significant difference according to year. The age distribution of patients was highest under age 10(33.4%). The ratio of male to female patient was 3.1: 1. Monthly or seasonal distribution if patients was not significantly different. 2. Of 42 cases, causative organisms were isolated in 31 cases. They are Trichophyton(T.) rubrum in 19 cases (61.3%), Microsporum(M.) canis in 6 cases (19.4%), T. mentcgrophytes in 5 cases (16.1%) and M. gypseum in 1 case(3.7%) in tbe order of decreasing frequncd M. canis was the main causative organisrn in children under age 10. In the age group after 10, T. rubrum was predominated. T. rubrum infection was most frequently seen in spring, T. mentagrphates infection was seen more in winter and M. canis infectior in autumn. 3. Classic annular types were seen most frequently in the cases caused by T. rubrum and T. mentagrophytes. Papular types were seen most commonly in the case caused by M. canis. Multiple facial lesions were seen in T. rubrum infection (2 cases) and Of canis infection (1 case). Tinea faciale simulated several other dermatoses. These were contact, dermatitis, lupus erythematosus, photosensitive dermatosis, rosacea, granuloma annulare and acne. Of these, tinea faciale simulated contact dermatitis most frequently. Coexisting fungal infections were found in 7 patients and tinea corporis was most frequently present. Topical antifungsl agent was tried alone in 22 cases, and topical and systemic antifungal agent were combined in 20 cases.
Acne Vulgaris ; Age Distribution ; Child ; Daegu ; Dermatitis ; Dermatitis, Contact ; Female ; Granuloma Annulare ; Humans ; Korea ; Male ; Outpatients ; Rosacea ; Seasons ; Skin Diseases ; Tinea*

No abstract available.
Free Tissue Flaps* ; Upper Extremity*

No abstract available.
Femur Neck*

Various susceptibility tests have been used to determine minimal inhibition concentration (MIC) of dermatophytes. They have limitations to apply practically because they need long time to determine MiC. Authors examined MIC of T. rubrum to ketoconazole and itraconazole using 96- well microplate and 24-well macroplate by method of Granade and Artis and tried to check the possibility of this method on clinical application. Nine strains of T. rubrum from patients with dermatophytosis were used. Evaluations of the factors affecting MIC were also tried. The results as follows. 1. Effect of inoculation density on determination time and MIC: Determination of MIC were possible in 4th days after inoculation at higher inoculation density (aborbance 2.0, 1.0) compared to 6th days at lower inoculation density (absorbance 0.5, 0.25). 2. Effect of incubation temperature on MIC: When incubating at 37℃, MIC were below 0.006-0.04µg/ml to ketoconazole and below 0.006-0.04µg/ml to itraconazole while at 25℃ 0.08-5.68µ8/ml to ketoconazole and 0.006-0.71µg/ml to itraconazole. Significant reduction of MIC was observed at 37℃ compared to 25℃. 3. Effect of container size on determination time and MIC: When incubating in 96–well microplate and 24-well macroplate, determination of MIC was possible in 4th to 6th days after inoculation in broth-containig 96-well microplate compared to 8th to 12th days in broth-containing 24-well macroplate. But no difference in MIC was observed between different container size. 4. Effect of media on MIC: When using broth as media, MIC were below 0.006-5.68µg/ml to ketoconazole, below 0.006-0.36µg/ml to itraconazole in broth-containg 24-well macroplate. When using agar as media, MIC were below 0.006-5.68 µg/ml to ketoconazole, below 0.006-5.68 µg/ ml to itraconazole in agar-containing 24-well macroplate. 5. These findings confirm that determination of MIC of dermatophtes by method of Granade and Artis is fast and simple technique for antifungal susceptibility test.
Agar ; Arthrodermataceae ; Humans ; Itraconazole ; Ketoconazole ; Methods* ; Tinea ; Trichophyton*

No abstract available.
Apgar Score* ; Humans ; Smoke* ; Smoking*

According to previous reports, ankle arthrodesis is regarded as the best reconstructive procedure after limb salvage surgery for osteosarcoma of the distal tibia. Of the many arthrodesis options, vascularized fibular graft (VFG) is widely accepted as the most successful method. However, reconstruction using VFG is not always possible, because VFG is a complicated surgical procedure and is associated with high rates of morbidity at donor sites. The authors devised a novel reconstructive surgical procedure that exploits the osteogenic potential of the periosteum. A 10-year-old female patient with osteosarcoma of the distal tibia underwent limb salvage surgery and the ipsilateral distal fibula and periosteal sleeve were transported to the defect for ankle arthrodesis. The transported fibula and periosteal new bone formation acted as a dual strut bone graft providing better stronger stability than fibula alone transfer. The authors believe the proposed procedure is an easier alternative to the surgically demanding VFG method.
Animals ; Ankle ; Arthrodesis ; Child ; Durapatite ; Female ; Fibula ; Humans ; Limb Salvage ; Osteogenesis ; Osteosarcoma ; Periosteum ; Reconstructive Surgical Procedures ; Tibia ; Tissue Donors ; Transplants

The pathogenesis of lupus er thematosus(LE) appears to be multifactorial, including genetic, hormonal and environmental influences. Genetic factors have long been suspected to an important role in its pathogenesis. This was been shown in family studies and twin studies. We report a family in which mother developed SLE and son developed DLE. The mother, 35 year old female, had hyperpigmcnted brownish macules and atrophic scars on the face and also complained of fever, chill and arthralgia for 2 years. The clinical, laboratory and histopathological findings showed characteristic features of systemic lupus erythematosus. she had been treated with systemic prednisolone, hydrcxychloroquin sulfate and topical corticosteroid ointment for about 4 years resulting favorable improvement skin lesions. Laboratory studies during her course had demonstrated persist leukopenia, peckled pattern ANA and VDRL positive. The son, 10-year-old, had peasized, multiple erythematous papules and plaques on the face and arms for 2 months. The lirical, laboratory and histopathological findings showed characteristic features of discoid lupus erythematosus. He was treated with systernic prednisolone for 2 years, hydroxychloroquin sulfate and topical corticosteroid ointment for abcut 4 years resulting nearly all clearing of skin lesions with slighthly hyperpigmentation. Laboratory studies during his course had demonstrated only weakly ANA positive.
Adult ; Arm ; Arthralgia ; Child ; Cicatrix ; Female ; Fever ; Humans ; Hyperpigmentation ; Leukopenia ; Lupus Erythematosus, Discoid ; Lupus Erythematosus, Systemic ; Mothers* ; Naphazoline ; Prednisolone ; Skin

Eimeria tenella, an intracellular protozoan parasite infecting the epithelial cells of the ceca of chickens, causes severe diarrhea and bleeding that can lead its host to death. It is of interest that E. tenella first penetrate into the mucosal intraepithelial lymphocytes (IEL) before they parasitize crypt or villous epithelial cells. This in vitro study was undertaken to know whether the penetration of E. tenella into such a lymphoid cell is a beneficial step for the parasite survival and development. Three sequential experiments were performed. First, the in vitro established bovine kidney cell line, MDBK cells, were evaluated for use as host cells for E. tenella, through morphological observation. Second, the degree of parasite development and multiplication in MDBK cells was quantitatively assayed using radioisotope-labelled uracil (3H-uracil). Third, the E. tenella sporozoites viability was assayed after preincubation of them with chicken spleen cells. E. tenella oocysts obtained from the ceca of the infected chickens were used for the source of the sporozoites. Spleen cells (E) obtained from normal chickens (FP strain) were preincubated with the sporozoites (T) at the E:T ratio of 100:1, 50:1 or 25:1 for 4 or 12 hours, and then the mixture was inoculated into the MDBK cell monolayer. Morphologically the infected MDBK cells revealed active schizogonic cycle of E. tenella in 3-4 days, which was characterized by the appearance of trophozoites, and immature and mature schizonts containing merozoites. The 3H-uracil uptake by E. tenella increased gradually in the MDBK cells, which made a plateau after 48-60 hours, and decreased thereafter. The uptake amount of 3H-uracil depended not only upon the inoculum size of the sporozoites but also on the degree of time delay (preincubation; sporozoites only) from excystation to inoculation into MDBK cells. The 3H-uracil uptake became lower as the preincubation time was prolonged. In comparison, after preincubation of sporozoites with spleen cells for 4 or 12 hours, the 3H-uracil uptake was significantly increased compared with that of control group. From the results, it was inferred that, although the penetration of E. tenella sporozoites into the lymphoid cells such as IEL is not an essential step, it should be at least a beneficial one for the survival and development of sporozoites in the chicken intestine.
Cattle- ; Cell-Line ; Cells,-Cultured ; Chickens- ; English-Abstract ; *Eimeria-growth-and-development ; *Kidney-parasitology ; *Lymphocytes-parasitology ; *Spleen-cytology

PURPOSE: Porous orbital implant Medpor(R) which is made of polyethylene is being widely used currently. Compared with previously used porous orbital implants, it is somewhat preferred due to cheaper and easier usage but reports on its postoperative complications are not sufficient. We report the first case of Medpor(R) infection developed domestically. METHODS: A 20 year-old male patient was admitted with Medpor(R) infection 14 months after Medpor(R) orbital implant insertion. He was treated with antibiotics. RESULTS: Infection was controlled with antibiotics without implant removal. Implant exposure occurred after infection control so dermis graft was done.
Anti-Bacterial Agents ; Dermis ; Humans ; Infection Control ; Male ; Orbit* ; Orbital Implants* ; Polyethylene ; Postoperative Complications ; Transplants ; Young Adult