1.Clinical characteristics of vibrio vulnificus infection.
Myung Geun SHIN ; Jong Hee SHIN ; Dong Wook YANG
Korean Journal of Clinical Pathology 1993;13(2):287-293
No abstract available.
Vibrio vulnificus*
;
Vibrio*
2.Evaluation of ATB 32GN system for identification of vibrio vulnificus.
Jong Hee SHIN ; Myung Geun SHIN ; Dong Wook YANG
Korean Journal of Clinical Pathology 1993;13(2):281-286
No abstract available.
Vibrio vulnificus*
;
Vibrio*
3.The Effect of Cyclic Tensile Load on Various Tibial Fixation Techniques in Anterior Cruciate Ligament Reconstruction.
Eunk Kyoo SONG ; Jong Wook JUNG ; Sang Kyoo SHIN
Journal of the Korean Knee Society 2001;13(2):167-176
No Abstract Available.
Anterior Cruciate Ligament Reconstruction*
;
Anterior Cruciate Ligament*
4.Cellular Fatty Acid Analysis of Vibrio vulnificus Strains Isolated from Korea.
Jong Hee SHIN ; Dong Wook RYANG ; Myung Geun SHIN ; Soon Pal SUH ; Kyung Sook BAE
Journal of the Korean Society for Microbiology 1997;32(1):27-38
Vibrio vulnificus infection is one of the most fatal diseases in Korea. This study was undertaken to determine the cellular fatty acid (CFA) compositions of ninety-five clinical strains of V. vulnificus isolated from Korea during 1985-1995. We compared these results with the CFA profile of V. vulnificus in the Microbial Identification System (MIS) (CLIN library version 3.9; Microbial ID Inc., Newark, Del.), and also evaluated the MIS ability to identify V. vulnificus. Subgrouping of V. vulnificus by CFA analysis was performed and its results were compared with those of serotyping. Most of the CFAs in V. vulnificus strains were similar to the CFA profile of V. vulnificus in the MIS, but some distinctive differences were observed. First, means of two major CFAs, 16:0 and 16:1w7c, were 22.16% and 18.26% in this study, but 23.52% and 25.44% in the MIS respectively. Second, all isolates had 11:Oiso3OH, which was not present in the MIS. Eighty-five strains (89.5%) disclosed the first choice identification of V. vulnificus by the MIS, but only two strains (2.1%) were identified with SI values of 0.6. Remaining ten strains (10.5%) showed 'NO MATCH' results. Cluster analysis of CFA could separate V. vulnificus into nine subgroups, and predominant subgroups were subgroup VII (45 strains) and V (36 strains). There was heterogeny between subgroups by CFA and serotypes of V. vulnificus. The strains of 04 serotype which accounted for 80% (76/95) of the isolates were distributed into six different subgroups such as VII (40 strains), V (27 strains), III (4 strains), I (2 strains) and VI (1 strain). These showed that V. vulnificus strains isolated from Korea had different characteristics in the CFA composition in comparison with the MIS V. vulnificus library. Subgrouping by the CFA analysis might be a useful tool for the epidemiological study of V. vulnificus infection in Korea.
Korea*
;
Serotyping
;
Vibrio vulnificus*
;
Vibrio*
5.Effect of Epidermal Growth Factor on The Production of Cortisor, Thyroxine, and Prolactin in Fetal Rabbits.
Soo Pyung KIM ; Jong Chul SHIN ; Jong Kun LEE ; Yong Wook KIM ; Tae Sup BYUN ; Jae In SHIN ; Chong Seong YI ; Jong Gu RHA
Korean Journal of Obstetrics and Gynecology 1998;41(12):3029-3033
Respiratory distress syndrome (RDS) is a major cause of death in premature neonates, and it is caused by the failure of morphological and biochemical lung maturation (synthesis and secretion of lung surfactant). It is known that cortisol, thyroxine, prolactin, epidermal growth factor (EGF), and estrogen accelerate the lung maturation. Cortisol and thyroxine are currently used in the antenatal treatment for the prevention of RDS in premature neonates. In order to evaluate the effect of EGF on the levels of cortsol, thyroxine, and prolactin, this study was undertaken. Phosphate buffered saline (PBS) with and without EGF was directly injected into the 25 days gestational fetus in uterus. Blood was collected for the measurement of cortisol, thyroxine, and prolactin one day or two days after the injection. Body weights and lung weights were also measured. The results were as follows: 1. There was no significant difference in body weights and lung weights between PBS-treated group(control group) and EGF-treated poup(experimental group), 24 hours and 48 hours after the injection. 2. 24 hours after the injection, the levels of cortisol were significantly inaeased in the EGF-treated group compared with those in the PBS-treated group. However 48 hours after the injection, there was no significant difference in the levels of cortisol between the two groups. The levels of thyroxine and prolactin in the EGF-treated group did not significantly differ from those in the PBS-treated group 24 hours and 48 hours after the injection. In conclusion, in vivo, the synthesis of cortisol may be affected by EGF treatment, which suggests that the action of EGF for lung maturation may be partially mediated by the increased endogenous levels of cortisol.
Body Weight
;
Cause of Death
;
Epidermal Growth Factor*
;
Estrogens
;
Fetus
;
Humans
;
Hydrocortisone
;
Infant, Newborn
;
Lung
;
Prolactin*
;
Rabbits*
;
Thyroxine*
;
Uterus
;
Weights and Measures
6.Studies on the Improved Technique of the Anterior Cervical Interbody Fusion for Herniated Cervical Disc.
Wook AHN ; Ho SHIN ; Jong Ghee KIM
Journal of Korean Neurosurgical Society 1981;10(1):189-198
A total of 236 anterior cervical interbody fusion has been performed. In 76 cases mostly Cloward's original method has used. During these operations several technical modifications were made. With these technique 159 cases were operated and showed marked beneficial results. 1. For widening of the interspace, a halter traction was better than the vertebra spreader. 2. Extension of the cervical spine when drilling of the vertebral bodies prevented the post-operative flexion deformity of the neck. 3. The dowel size, 2mm. In diameter larger than the drill hole was used and the cortical end plate of the dowel was fixed st the anterior edges of the vertebral bodies. 4. It was safe to leave the posterior edges of the vertebral bodies when drilling. 5. If the dowel was too thin, 2 pieces of the graft were packed. 6. Post-operative pain on the dornor bone site and walking difficutly wer minimized when the dowel was obtained from the inner aspect of the ileum. when the dowel was obtained from the inner aspect of the ileum. Many technical fitfalls of this type of operation were analyzed and discussed the improved surgery.
Congenital Abnormalities
;
Ileum
;
Neck
;
Spine
;
Traction
;
Transplants
;
Walking
7.Therapeutic Effect of Minocycline on Confluent and Reticulated Papillomatosis.
Sung Wook SHIN ; Jong Gu KIM ; Seung Hoon CHA ; Seok Don PARK
Korean Journal of Dermatology 1998;36(2):204-209
BACKGROUND: Confluent and reticulate papillomatosis(CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed. OBJECTIVE: We attempted to evaluate the therapeutic effect of oral minocycline for CRP. METHOD: Nine patients(age range, 14 to 38; mean age, 21years) with CRP were included in this study. They took minocycline 100mg daily. The therapeutic effect was evaluated weekly by 5 scoring systems according to the percentage clearing of the skin lesion: poor (score 1), <25% clearing; fair (score 2), 26-50%; good (score 3), 51-75%; excellent (score 4), 76-95%, clear(score 5), >95%. RESULTS: Two out of 9 patients showed complete clearing(score 5) of the skin lesions within 2 weeks. Seven patients revealed incomplete clearing(score 4) within 3 to 8 weeks. The mean scoring for 9 CRP patients was 4.2. Recurrences were noted in two patients at 24 and 26 months, respectively, but they responded to re-treatment with minocycline. The patients did not show any adverse reactions apart from two patients who developed mild pruritus. CONCLUSION: We recommend minocycline as the first choice of treatment for CRP because minocycline is safe, economic and effective.
Humans
;
Minocycline*
;
Papilloma*
;
Pruritus
;
Recurrence
;
Skin
8.A clinical and histologic study of 71 cases of basal cell carcinoma.
Ja Kyoung SHIN ; Hye Kyoung AHN ; Chun Wook PARK ; Jong Min KIM ; Cheol Heon LEE
Korean Journal of Dermatology 1992;30(5):585-591
A clinical and histologic survey was done on 71 cases of basal cel carcinoma(BCC) filed at Department of Clinical Fathology, Kang Nam, Han Kang, and Kang Dong Sacred Heart Hospital during past 13 year s from 1979 to 1991. The results were summerized as follows: 1. Of all malignant skin tumors BCC accounted for 31.6%. The frequency of BCC in the total number of outpatients visiting the Department of Dermatology was 0.06%. 2. The ratio of men to women with HCC was 1:1.03. 83.8% of the pat.ients with BCC were older than the age of l0 years with the mean age of 56.9 years. 3. 83.8% of the BCC appared in the face, especially on the nose(25.4%), eyelid(20.3%). 4. On the basis of classification of Lever et al, the solid type(66.7% ) was the most com mon histologic pattern, followed by the adenoid(8.8%), pigmented(8.8%), and etc. By the classification of Farmer et al, the nodulocystic type(35.1% ) was the most common histologic pattern followed by infiltrative(31.6%), adenoid(8.8%), pigmented(8.8%), and etc. By the classification on Sexton et al, in the order of decreasing frequency, liistologic subtypes were the nodular(43.9%), mixed (22.8%), infiltrative(19.3%), supeficial(3.5%), morpheic(3.5%), and micronodular(3.5%).
Carcinoma, Basal Cell*
;
Classification
;
Dermatology
;
Female
;
Heart
;
Humans
;
Male
;
Outpatients
;
Skin
9.Captopril in Children with Renovacular Hypertension.
Yong CHOI ; Hoan Jong LEE ; Hee Young SHIN ; Kwang Wook KO ; Chang Yee HONG
Journal of the Korean Pediatric Society 1985;28(1):58-67
No abstract available.
Captopril*
;
Child*
;
Humans
;
Hypertension*
10.Two Cases of Multiple Neurilemmomas.
Ja Kyoung SHIN ; Chun Wook PARK ; Jong Min KIM ; Cheol Heon LEE
Korean Journal of Dermatology 1993;31(1):139-142
We report two cases of multiple neurilemmomas occured in a 17-year-old female and in a 76-year-old male. Both cases were histopathologically confirmed as neurilemmoma and immunohistochemical study showed S-100 protein in the tumor cells of case 1.
Adolescent
;
Aged
;
Female
;
Humans
;
Male
;
Neurilemmoma*
;
S100 Proteins