The authors present a case of bilateral retinoblastoma occured in a six months old baby. The right eye, the advanced, was enucleated immediately and the left eye was treated with x-ray radiation giving 5,400r (tumor dose) in four weeks. A cataract developed in five years after the radiation therapy, which masked the pictures of the fundus and was extracted intracapsularily using alpha-chymotripsin. After the surgery, repeated funduscopy revealed no definite signs of recurrence.
Cataract ; Masks ; Recurrence ; Retinoblastoma*

The experimental endophthalmitis was obtained by the injection of streptococcus hemolyticus into the anterior chamber of the rabbit's eyes and the effect of ginseng was observed. Topical use of atropine and oxytetracycline ointments was done for 11 days, and systemic administration of chloramphenicol and procaine penicillin was done for 8 days in infected rabbits. In the grade of aqueous flare the inflammatory sign seemd to be relatively milder in the group of pretreatment with ginseng than the others by the slit lamp biomicroscopic examination on 11 th day of infection. But lymphocytic cellular infiltration of the iris and ciliary body associated with neovascularization of the iris were thought to be relatively milder in the control group than the other ginseng treated group by histopathological examination. Above two different findings showed that the result of this study is not reliable, and other studies shall be done further more.
Anterior Chamber ; Aqueous Humor ; Atropine ; Chloramphenicol ; Ciliary Body ; Endophthalmitis ; Iris ; Ointments ; Oxytetracycline ; Panax* ; Penicillin G Procaine ; Rabbits ; Streptococcus*

No abstract available.
Echocardiography ; Hepatopulmonary Syndrome*

101-103 The authors have recently experienced a case of subretinal cysticercosis which simulated choroidal melanoma. Although it is benign variety, the eye was enucleated since the lesion was in the macular area and the patient was thought not to be able to gain an useful central vision after treatment. In the review of the literatures, the subretinal cysticercosis seems to occur much more frequently than the other ocular cysticercosis and it is very hard to get an exact diagnosis. The surgical removal may be difficult in procedure and the prognoses are poor in the cases of macular invorvement.
Choroid ; Cysticercosis ; Diagnosis ; Humans ; Melanoma ; Prognosis

Authors experienced 100 cases of retrobulbar optic neuritis among the patients who visited the Chang Shoo Choi Eye Clinic during the last 2 years, from September 1, 1964 to August 31, 1966. The chief complaints are asthenopia, blurring vision, ocular pain, headache and photophobia. Of 100 cases, 46 cases wanted to be refracted. The corrected visual acuities are not always poor, though they are very variable from time to time as the tests are processing. The most cases revealed central relative scotomas instead of cecocentrals as previously believed. Fields are taken with glasses if corrected. In our cases, the age distribution of the patients are very interesting, the most susceptible age groups are 11~13 years.
Age Distribution ; Asthenopia ; Eyeglasses ; Glass ; Headache ; Humans ; Optic Neuritis* ; Photophobia ; Scotoma ; Vision, Ocular ; Visual Acuity

BACKGROUND: Dopamine receptors have been regarded as a strong candidate involved in etiology of schizophrenia and a target for various antipsychotic drugs. The purpose of our study was to investigate whether dopamine D1 receptor(DRD1) gene polymorphisms would predict the treatment response to antipsychotics in schizophrenia. METHOD: One hundred thirty-four schizophrenic patients, who met DSM-IV criteria for schizophrenia were entered into a 48-week study. The psychopathology of the patients was assessed at baseline, 12th, 24th, 48th weeks of treatment by PANSS. Responders were defined by a 20% of the reduction in total PAnSS score at end point. The genomic DNA fragment corresponding to nucleotides of dopamine D1 receptor gene was amplified by polymerase chain reaction(PCR). RESULT: Neither allelic frequencies nor genotypes for dopamine D1 receptor differed significantly between responders and non-responders. Also, there was no difference of changes of PANSS scores among three genotype groups of the dopamine D1 receptor. CONCLUSION: Allelic variation in the dopamine D1 gene is not associated with individual differences in antipsychotic response.
Antipsychotic Agents ; Diagnostic and Statistical Manual of Mental Disorders ; DNA ; Dopamine* ; Genotype* ; Humans ; Individuality ; Nucleotides ; Psychopathology ; Receptors, Dopamine ; Receptors, Dopamine D1* ; Schizophrenia

We had a retrospective study for taumatic fracture of spines with simple X-ray and CT. During the period of 2years from June 1983, the radiological and clinical evaluation had been made on 36 patients suffered from traumatic fracture of spines which were confiremd by the radilgocial examination. The results were as follows; 1.Among 36 patients, single spinal injury was 26 cases(72.2%), multiple level injuries was 10 cases(27.7%). 2. Levelof spinal injuries were as follows; Most frequent site was thoracolumbar junction (T11-L2) in 19 cases(52.7%), andlower cervical spine(C3-C7) in 9 cases(25%). 3. Simple fracture was in 15 cases(41.6%), burst fractures was in 21cases(58%). Neurologic symptoms were appeared in 11 cases(52%) in 21 cases of burst fractures. 4. Manifestationsof spinal canal narrowing: 2 of 15 cases in simple fracture, all of 21 cases of burst fractures,and we were foundexactly posterior element fractures with CT, which were difficult to detect with simple X-ray film. 5. Multiplanar reconstruction images were more favorable to detect the distraction of facet joint, fracture through the vertebralendplate, subluxation and kyphosis, which were difficult to detect with axial CT images.
Humans ; Kyphosis ; Neurologic Manifestations ; Retrospective Studies ; Spinal Canal ; Spinal Fractures ; Spinal Injuries ; Spine ; X-Ray Film ; Zygapophyseal Joint

Authors observed many cases of vertical deviation in the patients complaining of marked asthenopia. Of 1275 cases who had refraction, there were 183 cases of vertical deviation (13.54%) in our clinic, during the last 2 years from July 1, 1973 to August 31, 1975. In the series of our observation, the females were much more frequent than the males in numbers, especially after 30 years of age group. The right hyperphoria was more frequent than the left. In the most of the vertical deviation, the degrees of deviation were less than one prism diopter and associated with low grade of refractive errors (less than +/- 0.5 diopter). If the marked refractive error was corrected without correction of vertical deviation, the headache appeared to be increased in the cases of marked refractive error associated with vertical deviation. In the majority of the cases who had vertical deviation, the headache (marked asthenopia) was complained of and in the many cases of them the head was tilted slightly to one shoulder. 1) In the many cases, the headache was occipital in character. 2) The headache seemed to be marked in looking the moving picture or on walking the streets (by the looking of moving objects). 3) The headache started easily by looking out of door in the railway journey or driving. 4) The headache occured usually by the exercise or home work and increased in the afternoon while they were comfortable early in the morning.
Asthenopia ; Female ; Head ; Headache* ; Humans ; Male ; Refractive Errors* ; Shoulder ; Walking

No abstract available.
Age Factors* ; Hematoma, Subdural, Chronic*

A case of cerebral paragonimiasis associated with right homonymous hemianopsia was reported in view of its rarity and a review of the related literaturs was made. The patient was 14 years old man. He had been suffering from poor visual acuity for 2 months and headache for 7 years. He had hsitory of indigestation of crayfish during measle infection. Skull x-ray revealed calcification on temporo-occipital region. He had been treated with bithionol, daily doses of 20mg/kg of body wt. for 70 days. And the rsult was improvement.
Adolescent ; Astacoidea ; Bithionol ; Headache ; Hemianopsia* ; Humans ; Paragonimiasis* ; Skull ; Visual Acuity