1.Epidemic Investigation of Pyrogenic Reactions caused by Contaminated Intravenous Products.
Hyang Soon OH ; Eui Jong KIM ; Jong Song SECK ; Hoan Jong LEE ; Myoung Don OH ; Kang Won CHOE
Korean Journal of Nosocomial Infection Control 2005;10(1):1-8
PURPOSE: This study was conducted to investigate the epidemic pyrogenic reactions that occurred hospital-widely in 51 patients on 30-31 Mar. 1995 at a tertiary, educational, and acute care hospital. METHODS: The remained intravenous (IV) drugs and IV fluids that were infused to patients (N=51) who developed pyrogenic reactions were cultured and tested pyrogenic matter. Pyrogenic test was done by Limulus Amebocyte Lysate (PyrotellRMA,USA). RESULTS: IV normal saline 50 cc bottles (AAXSAT and AAX5AV) those were collected being used from case patients, and new bottles stocked in the drug storage were positive to pyrogenic test. Used normal saline collected from case patients were cultured coagulase-negative Staphylococus. Moreover the company, manufacturer of these fluids reported the positive pyrogenic test on these IV fluids (AAXSAT and AAX5AV). CONCLUSION: This epidemic was a pyrogenic reaction for infused the intrinsic contaminated fluid with pyrogen. We could prevent not the additional pyrogenic reactions in study hospital but national wide epidemics to apply the rapid and well-designed epidemic investigation and infection control.
Bacteremia
;
Cross Infection
;
Drug Storage
;
Horseshoe Crabs
;
Humans
;
Infection Control
2.Tuberculous fistula-in-ano.
Khyu Hyung CHOE ; Wook KIM ; Il Young PARK ; Jong Man WON ; Eung Seul HYUN
Journal of the Korean Society of Coloproctology 1993;9(2):179-184
No abstract available.
3.Tuberculous fistula-in-ano.
Khyu Hyung CHOE ; Wook KIM ; Il Young PARK ; Jong Man WON ; Eung Seul HYUN
Journal of the Korean Society of Coloproctology 1993;9(2):179-184
No abstract available.
4.Three Cases of Pneumoperitoneum in Ventilated Newborns.
Ho Young LEE ; Won Kju CHOE ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1995;38(7):1006-1011
No abstract available.
Humans
;
Infant, Newborn*
;
Pneumoperitoneum*
5.Variations of antimicrobial prescription patterns among some hospitals.
Young Soo SHIN ; Yong Ik KIM ; Young Seong LEE ; Chang Yup KIM ; Kang Won CHOE ; Hoan Jong LEE
Korean Journal of Infectious Diseases 1992;24(4):271-284
No abstract available.
Prescriptions*
6.Preoperative Nasal Carriage of Methicillin-Resistant Staphylococcus aureus and the Risks of Nosocomial Infection in Cardiac Surgery Patients.
Hyang Soon OH ; Kyang Ah KUM ; Myong Don OH ; Hoan Jong LEE ; Eui Chong KIM ; Kang Won CHOE
Korean Journal of Nosocomial Infection Control 2006;11(1):27-34
BACKGROUND: This study was conducted to investigate whether the preoperative nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) was a risk factor for surgical site infections and nosocomial infections in open heart surgery patients. METHODS: From June 10, 2002 to October 30, 2002, data were collected by prospective surveillance carried out by infection control nurses. Nasal swabs were taken from patients (N= 106) on the day before surgery. The swabs were incubated in staphylococcal broth for 24 hours, and then it was incubated on mannitol salt agar for 24 hours. Muller-Hinton agar supplemented with oxacillin (6 microgram/mL) was used to identify MRSA. RESULTS: Among the study patients (N=106), four(4/106, 3.8%) were identified as MRSA carriers and nine (9/103 , 8.7%) developed nosocomial infections, including three patients (3/103 , 2.9%) who had postoperative mediastinitis Preoperative nasal carriage of MRSA was not associated with nosocomial infections nor surgical site infections (P>0.05). However, the length of hospital stay prior to nasal swab or surgery was found to be associated with MRSA carriage (OR=1.108, 95%CI: 1.026-1.197) or nosocomial infections (OR=1.087, 95%CI: 1.017-1.161). Additionally, the patients with nosocomial infections were more likely than those without to stay in the hospital for a longer period after surgery (P<0.00l). CONCLUSION: Preoperative nasal carriage of MRSA by the patient was not identified as a risk factor for surgical site infection and nosocomial infections in open heart surgery.
Agar
;
Cross Infection*
;
Humans
;
Infection Control
;
Length of Stay
;
Mannitol
;
Mediastinitis
;
Methicillin Resistance*
;
Methicillin-Resistant Staphylococcus aureus*
;
Oxacillin
;
Prospective Studies
;
Risk Factors
;
Thoracic Surgery*
7.Subcutaneous Panniculitic T-cell Lymphoma.
Sang Won KIM ; Jang Oh KIM ; Jong Woo KIM ; Dong Seok KIM ; Jung Yoon CHOE ; Yong Jin KIM
Annals of Dermatology 1996;8(2):158-163
No abstract available.
Lymphoma, T-Cell*
;
T-Lymphocytes*
8.Scrub Typhus in a Pregnant Woman: No Evidence of Intrauterine Infection.
Ji Hwan BANG ; Young Ju CHOE ; Yo Han JOH ; Ui Seok KIM ; Jong Wook SHIN ; Hang Rae KIM ; Myoung Don OH ; Ik Sang KIM ; Kang Won CHOE
Korean Journal of Infectious Diseases 2001;33(6):453-455
Pregnancy with scrub typhus is a rare condition. A 30-year-old woman was infected with scrub typhus at the 35th week of gestation. She was treated successfully with azithromycin, and delivered her baby uneventfully. The baby developed no signs for scrub typhus, and thrived well. IgM antibodies to O. tsutsugamushi were undetectable in the baby's sera, and titers of IgG antibodies did not rise. The polymerase chain reaction of the cord blood for O. tsutsugamushi was also negative. We concluded that transplacental infection did not occur in this pregnant woman.
Adult
;
Antibodies
;
Azithromycin
;
Female
;
Fetal Blood
;
Humans
;
Immunoglobulin G
;
Immunoglobulin M
;
Polymerase Chain Reaction
;
Pregnancy
;
Pregnant Women*
;
Scrub Typhus*
9.A Case of Fatal Wegener's Granulomatosis without Anti-neutrophil Cytoplasmic Antibody (ANCA).
Hyun Jung LIM ; Yoon Seok CHOE ; Byung Soo KIM ; Seok Jong LEE ; Do Won KIM
Korean Journal of Dermatology 2008;46(8):1134-1137
Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis belonging to the small- to medium-sized vessel. A 46-year-old male presented with erythematous hard plaque on chest, calf and multiple subcutaneous nodules on buttock, upper arm. Incisional biopsy was done and the histopathologic finding revealed the features of necrotizing vasculitis with focal granulomatous inflammation in subcutaneous tissue. PNS MRI showed abnormal meningeal enhancement and lung HRCT imaging showed mild infiltration. Inspite of severe systemic involvement, serum tests about ANCA showed negative result. He was treated with systemic corticosteroid and cyclophosphamide pulse therapy. Initially his condition showed improvement but later the disease worsened.
Antibodies, Antineutrophil Cytoplasmic
;
Arm
;
Biopsy
;
Buttocks
;
Cyclophosphamide
;
Glycosaminoglycans
;
Humans
;
Inflammation
;
Lung
;
Male
;
Middle Aged
;
Subcutaneous Tissue
;
Thorax
;
Vasculitis
;
Wegener Granulomatosis
10.Serum Myoglobin as a Biochemical Marker to Rule Out Acute Myocardial Infarction.
Jang Young KIM ; Ju Yong LEE ; Jong Won HA ; Sung Oh HWANG ; Kum Soo PARK ; Seung Hwan LEE ; Junghan YOON ; Kyung Hoon CHOE
Korean Circulation Journal 1998;28(6):915-922
BACKGROUND: Diagnosis of AMI in the patients presenting with chest pain of an atypical nature or with a nondiagnostic ECG requires the evaluation of certain biochemical markers. Biochemical markers most often used for the early detection of myocardial damage are CK-MBact, troponin, and myoglobin. The clinical value of measuring serum myoglobin was compared to that of troponin and CK-MBact in the patient with acute chest pain syndrome. METHOD: We studied timed, sequential measurements of serum myoglobin, CK-MBact and troponin-T obtained from 72 patients who were admitted for the evaluation of suspected AMI within 12 hours after the chest pain onset. Patients with a history of recent trauma, cardiogenic shock, renal failure, or who had received recent cardiopulmonary resuscitation were excluded. We calculated the sensitivity, specificity, negative predictive value, and positive predictive value. Data were analyzed with the Chi-square test for differences in proportion. A value of p<0.05 was considered statistically significant. RESULT: 1) The mean time from symptom onset to arrival at the emergency department was 3.5+/-0.6 hours. 2) There were no statistical differences in age, sex and risk factors between AMI, angina pectoris and atypical chest pain group. 3) The negative predictive value of myoglobin was significantly higher than those of CK-MBact and troponin-T from 3 to 6 hours after the onset of chest pain. 4) The time to peak of myoglobin level was shorter than those of CK-MBact and troponin-T in AMI patients. CONCLUSION: Within 3 to 6 hours after the onset of symptoms, myoglobin is a better marker than CK-MBact or troponin-T in ruling out AMI for the patient with acute chest pain syndrome.
Angina Pectoris
;
Biomarkers*
;
Cardiopulmonary Resuscitation
;
Chest Pain
;
Diagnosis
;
Electrocardiography
;
Emergency Service, Hospital
;
Humans
;
Myocardial Infarction*
;
Myoglobin*
;
Renal Insufficiency
;
Risk Factors
;
Sensitivity and Specificity
;
Shock, Cardiogenic
;
Troponin
;
Troponin T