We have experienced an anesthetic management of 56-year-old male patient with carotid stenosis. Carotid endarterectomy was performed with processed electroencephalography (compressed spectral array, CSA) monitoring. Carotid endarterectomy has significant risk of perioperative stroke and myocardial infarction. For brain protection during carotid cross clamp, body temperature of patient was maintained at 33.5oC and thiopental was infused continuously to induce burst suppression. To maintain blood pressure during cross clamp, dopamine was infused continuously and phenylephrine was injected intermittently. CSA was performed to monitor thiopental-induced burst suppression and ischemic brain insult. After releasing carotid cross clamp, body temperature was raised to 35oC.
Blood Pressure ; Body Temperature ; Brain ; Carotid Stenosis ; Dopamine ; Electroencephalography ; Endarterectomy, Carotid* ; Humans ; Hypothermia ; Male ; Middle Aged ; Myocardial Infarction ; Phenylephrine ; Stroke ; Thiopental

No abstract available.
HL-60 Cells* ; Humans ; Mass Screening* ; Protein Kinases*

No abstract available.
Carcinoma, Hepatocellular*

PURPOSE: The purpose of this study was to seek ways to improve the quality of life of workers by separating workers into the low fatigue group and the severe fatigue group depending on the level of fatigue level, and analyzing and understanding the difference between quality of life and job stress according to the fatigue level. METHODS: For the 'Development of Mibyeong management system which was a consumer-directed health care service', the data of job stress, fatigue and quality of life was collected from 115 workers who visited the oriental hospitals located in J city and C city from Jul, 2012 to Dec, 2012. RESULTS: The severe fatigue group showed significantly higher job stress than the low fatigue group in physical environment (p=.004), job demand (p<.001), interpersonal conflict (p=.012), lack of reward (p=.062). The severe fatigue group showed lower degrees both in physical component summary (PCS) (p<.001) and mental component summary (MCS) (p<.001) measured by SF-12 and the quality of life (p<.001) measured by EQ5D than the lower fatigue group. A relatively strong negative correlation was found in the item of mental component summary (MCS) measured by SF-12. CONCLUSION: Considering our results that high fatigue level show negative impact on quality of life and job stress, we suggest to provide a variety of health promotion strategies to improve the quality of life through the prevention and relief of fatigue for workers.
Delivery of Health Care ; Fatigue* ; Health Promotion ; Quality of Life* ; Reward

No abstract available.
Aged* ; Humans ; Pneumonia*

No abstract available.
Aged* ; Humans ; Pneumonia*

No abstract available.
Capsaicin*

It is rare to find spontaneous cervical bleedings for which a wide variety of etiologies have been reported. We experienced a case of spontaneous cervical bleeding that caused emergency operation. We present this case with a review of the literature. This case demonstrates a potentially lethal complication in patients with neurofibroma. Neurofibroma is an inherited disease, classified as 'classical (type I, von Recklinghausen, multiple or peripheral neurofibromatosis)', 'central (type II, bilateral acoustic neurofibromatosis)' and other types. The pathognomic features of classical neurofibromatosis are cafe-au-lait spots and neurofibromas. Other clinical features are variably expressed and occurnece of severe hemorrhage is an unusual complication. Conservative management do not stop the hemorrhage. Surgical exploration must be undertaken for cure.
Acoustics ; Cafe-au-Lait Spots ; Emergencies ; Hemorrhage* ; Humans ; Neck* ; Neurofibroma ; Neurofibromatoses* ; Neurofibromatosis 1*

Hemangiopericytomas are very rare tumor in the paranasal sinuses. It is vascular tumor derived from Zimmerman's pericytes. Sinonasal hemangiopericytoma is generally benign with a low potential for local recurrence of metastasis via the blood stream and lymphatic system. They account for about 1% of all vascular tumors. About 5% of the cases occur in the nasal cavity and usually show well-differentiated tumors. The treatment of choice is surgical resection. We present a case of nasal hemangiopericytoma treated by endoscopic resection.
Hemangiopericytoma* ; Lymphatic System ; Nasal Cavity* ; Neoplasm Metastasis ; Paranasal Sinuses ; Pericytes ; Recurrence ; Rivers

BACKGROUND: The gastroepiploic artery is not only an alternative graft but also may be considered an important primary graft for coronary revascularization. However, the long-term patency of the gastroepiploic arterial graft is yet to be determined and the incidence of perioperative spasm and long-term patency of a coronary graft may be affected by the properties of the graft response to certain vasoactive substances. The reactivity of the gastroepiploic artery to vasoactive substances has not been studied extensively and the results of the studies are contradictory. MATERIAL AND METHOD: This study was designed to test the reactivity of human gastroepiploic artery to four constrictors and four relaxants. The middle sections of the human gastroepiploic arteries were collected from the patients undergoing gastrectomy and the arterial rings with intact endothelium were suspended in organ baths for isometric tension recording. RESULT: Epinephrine, norepinephrine, and potassium chloride induced the maximum constriction to higher forces (7.0+/-1.1g, 6.6+/-0.9g, and 6.5+/-1.1g) than 5-hydroxytryptamine did (3.8+/-1.7g, p<0.05). Nitroprusside and histamine induced almost full relaxation in the gastroepiploic arteries preconstricted with norepinephrine. There was no significant difference between two relaxants regarding maximum relaxation force. Acetylcholine induced the maximum relaxation to weaker force when compared with nitroprusside and histamine (p<0.05), and isoproterenol was the weakest of the relaxants (p<0.05 compared with acetylcholine). CONCLUSION: The gastroepiploic artery has a strong capacity of endothelium-dependent relaxation which could have an important influence on long-term patency. The gastroepiploic artery exhibits a potent contractility to catecholamines and the enhanced contractility may facilitate vasospasm in the presence of high circulating levels of catecholamines. Nitroprusside, a potent relaxant in gastroepiploic artery, might be beneficial for the treatment of gastroepiploic arterial graft spasm. The gastroepiploic arterial graft with intact endothelium may respond weakly to beta-adrenoceptor agonist and 5-hydroxytryptamine.
Acetylcholine ; Baths ; Catecholamines ; Constriction ; Endothelium ; Epinephrine ; Gastrectomy ; Gastroepiploic Artery* ; Histamine ; Humans* ; Incidence ; Isoproterenol ; Nitroprusside ; Norepinephrine ; Potassium Chloride ; Relaxation ; Serotonin ; Spasm ; Transplants