2.Evaluation of Dermal Measurement for Workers in Benzidine Dihydrochloride and Benzidine Based Dye Manufacturing Factory.
Hye Kyeong YEOM ; Jae Suk SONG ; Chi Nyon KIM ; Jong Uk WON ; Jaehoon ROH
Korean Journal of Occupational and Environmental Medicine 1998;10(1):83-94
This study is performed to evaluate usefulness of dermal measurement of benzidine and benzidine based dye as one of the occupational exposure assessment method for these compounds. We selected one benzidine manufacturing factory and one dye manufacturing factory in Incheon area. Eleven workers were for benzidine manufacturing factory and twenty four for dye. We analyzed relationships among air level, amount on skin and concentration of urinary metabolites for these compounds. Airborne levels of benzidine and dye were measured by NIOSH 5509, 5013 methods. Amount of these compounds on skin was measured with skin wipe method. Concentration of benzidine metabolites in urine was measured by High Performance Liquid Chromatography after alkaline hydrolysis. The amount of benzidine on hand skin was 25.05( - 233.2) ng/ur, and the amount of the neck was 2.01 ( - 11.9) ng/cm2 in the benzidine dihydrochloride manufacturing factory. The amount of benzidine on hand and neck skin has positive correlation with concentration of urinary monoacetyl benzidine (r=0.644, p < 0.05) . The amount of benzidine based dye on hand skin was 55.75( - 457.7) ng/cm2, and the amount of the neck skin was 18( - 284.7) ng/cm in benzidine based dye manufacturing factory The amount of dye on hand and neck skin has positive correlation with concentration of urinary benzidine for dye workers (r=0.467, p < 0.05). When assessing the exposure of workers who deal with benzidine, the amount of benzidine on skin should be measured for an accurate exposure assessment.
Chromatography, Liquid
;
Hand
;
Hydrolysis
;
Incheon
;
National Institute for Occupational Safety and Health (U.S.)
;
Neck
;
Occupational Exposure
;
Skin
3.A Case of Squamous Cell Carcinoma Arising in the Lesion of Chronic Discoid Lupus Erythematosus.
Kyung Seok OH ; Mu Hyun SONG ; Sung Yul LEE ; Jong Suk LEE ; Kyu Uang WHANG
Korean Journal of Dermatology 2000;38(3):399-403
Squamous cell carcinoma(SCC) is a recognized late complication of chronic discoid lupus erythematosus(CDLE). There are many case reports of SCC in white patients with chronic DLE. However, it is uncommon in blacks and Asians. The etiology of squamous cell carcinoma is multifactorial. The predisposing factors for the development of SCC in these patients include actinic keratosis, Bowen's disease, burn scars, arsenic keratosis, and chronic discoid lupus erythematosus. Of these causes, SCC developing in the lesions of CDLE is very rare. We report a patient who has been evaluated for ten years with a diagnosis of discoid lupus erythematosus and has squamous cell carcinoma.
African Continental Ancestry Group
;
Arsenic
;
Asian Continental Ancestry Group
;
Bowen's Disease
;
Burns
;
Carcinoma, Squamous Cell*
;
Causality
;
Cicatrix
;
Diagnosis
;
Humans
;
Keratosis
;
Keratosis, Actinic
;
Lupus Erythematosus, Discoid*
4.Clinical analysis of diagnostic method in obscure origin of gastrointestinal bleeding.
Jong Soo LEE ; Suk Won LIM ; Kyung Sup SONG ; Eung Kook KIM ; Sang Yong CHOO
Journal of the Korean Surgical Society 1992;42(2):267-274
No abstract available.
Hemorrhage*
5.Clinical analysis of diagnostic method in obscure origin of gastrointestinal bleeding.
Jong Soo LEE ; Suk Won LIM ; Kyung Sup SONG ; Eung Kook KIM ; Sang Yong CHOO
Journal of the Korean Surgical Society 1992;42(2):267-274
No abstract available.
Hemorrhage*
6.Clinical Study of the Paranasal Sinusitis in Childhood.
Young Suk SONG ; Kwang Nam KIM ; Gwi Jong CHOI ; Chong Moo PARK ; Hyung Seok LEE
Journal of the Korean Pediatric Society 1984;27(9):877-882
No abstract available.
Sinusitis*
7.Facial and Submandibular Cellulitis due to Staphylococcus Aureus.
Young Suk SONG ; Moon Ho CHUNG ; Gwi Jong CHOI ; Soo Jee MOON ; Chong Moo PARK
Journal of the Korean Pediatric Society 1983;26(7):663-666
No abstract available.
Cellulitis*
;
Staphylococcus aureus*
;
Staphylococcus*
8.A Case of Systemic Lupus Erythematosus Presented with Clinical Feature Resembling Multiple Sclerosis.
Chang Wan HAN ; Hoon Suk CHA ; Seong Wook KANG ; Yoon Jong LEE ; Yeong Wook SONG
The Journal of the Korean Rheumatism Association 1997;4(2):180-184
Systemic lupus erythematosus is a connective tissue disease which can affect every organ system. Neurologic abnormalities are common, occuring in approximately half of all patients at some time during the course of their illness. But symptoms of nervous system as the sole presenting symptoms occur in less than 1% of lupus patients. In patients initially presenting with neurologic symptoms and signs, differential diagnosis is difficult and sometimes it may be misdiagnosed. Therefore extensive laboratory investigations should be carried out in all patients with unusual neurological symptoms, since early diagnosis of lupus can help in providing effective treatment. We report a patient with systemic lupus erythematosus who presented with dysarthria and dysphagia resembling multiple sclerosis.
Connective Tissue Diseases
;
Deglutition Disorders
;
Diagnosis, Differential
;
Dysarthria
;
Early Diagnosis
;
Humans
;
Lupus Erythematosus, Systemic*
;
Multiple Sclerosis*
;
Nervous System
;
Neurologic Manifestations
9.Influences of Computer Works on Blink Rate and Ocular Dryness in Adolescents.
Jun Sung KIM ; Kyung Jun CHO ; Jong Suk SONG
Journal of the Korean Ophthalmological Society 2007;48(11):1466-1472
PURPOSE: To evaluate the change in blink rate in adolescents according to the type and duration of computer tasks and to analyze the risk of ocular dryness using an ocular protection index. METHODS: Fifteen male high school students played computer games and viewed Internet lectures for 20 minutes each. Blink rate was measured by USB camera, and ocular protection index (OPI, the ratio of BUT to inter-blink interval) was calculated for each subject during the two tasks. In addition, 7 of the 15 subjects played computer games again for 40 minutes on another day, and the change in blink rate according to the duration of computer games was observed. RESULTS: The average blink rate was 5.44+/-3.29 per minute (median 5, range 2-12.75) while playing computer games and 20.63+/-11.21 per minute (median 18.25, range 4.93-42.2) while viewing Internet lectures, and this difference was statistically significant (p=0.001). The percentage of subjects with OPI values less than 1 was 53% for computer games and 13% for Internet lectures (p=0.025). While playing computer games for 40 minutes, the mean of total blinks during ten-minute intervals decreased over time: 59.43 times (median 57) during the first 10 minutes, 33.86 times (median 41) during the last 10 minutes. CONCLUSIONS: The blink rate in adolescents was significantly lower and the risk of ocular dryness was higher while playing computer games compared with that of viewing internet lectures. As playing time increased, the blink rate decreased and risk of ocular dryness increased.
Adolescent*
;
Humans
;
Internet
;
Lectures
;
Male
;
Video Games
10.Effect of 1,25 dihydroxy-vitamin D3 and physiological inducers on the expression of interleukin-1?gene in the human myeloid leukemic cells.
Jong Suk OH ; In Chol KANG ; Jin JEONG ; Boo Ahn SHIN ; Myung Ja SONG ; Hyun Chul LEE
Journal of the Korean Society for Microbiology 1993;28(1):69-79
No abstract available.
Humans*