1.Efficacy of Sotalol and Amiodarone for Atrial Fibrillation.
Hye Lim OH ; Woo Shik KIM ; Myung Im KIM ; Ho Jong LEE ; Heung Sun KANG ; Chung Whee CHOUE ; Kwon Sam KIM ; Jung Sang SONG ; Jong Hoa BAE
Korean Circulation Journal 2001;31(2):210-216
BACKGROUND AND OBJECTIVES: Atrial fibrillation(AF) is the most frequently encountered arrhythmia in clinical practice. Pharmacologic therapy has been advocated for both immediate restoration of sinus rhythm and prevention of recurrent AF. Because conventional antiarrhythmic therapy is often ineffective in maintaining sinus rhythm or is associated with adverse side effects in patients with AF, recent interest has focused on the use of class III antiarrhythmic agents. This study investigated the efficacy and safety of sotalol and amiodarone for conversion of chronic AF and prevention of recurrent AF. MATERIALS AND METHOD: Thirty six patients with AF were firstly received sotalol by prospective study protocol. The patients were classified as having paroxysmal AF(PAF, N=2) or chronic AF(CAF, N=4) based on AF pattern. If the patients with CAF did not convert to sinus rhythm or the patients with PAF recurred in AF, the patients were received second agents(amiodarone). Patients were followed up for one year. RESULTS: Among the 12 patients with PAF receiving sotalol, 10(83.3%) patients remained in normal sinus rhythm for average 9.4+/-3.6 months. Sotalol was replaced by amiodarone in the remaing 2 patients with arrhythmia recurrence and 1 of the 2 patients remained in sinus rhythm during the follow-up period. In the case of 24 patients with CAF, conversion to sinus rhythm was achieved in 5(20.8%) patients with sotalol. Among the patients with CAF who were not respond to sotalol, 17 patients received amiodarone subsquently and 3 patients successfully converted to sinus rhythm. There were no proarrhythmic effects related to both agents during the study period. CONCLUSION: Both sotalol and amiodarone appear to be less effective in the termination of CAF, but sequential use of these two agents seem to be very effective for the prevention of recurrence of PAF.
Amiodarone*
;
Arrhythmias, Cardiac
;
Atrial Fibrillation*
;
Follow-Up Studies
;
Humans
;
Prospective Studies
;
Recurrence
;
Sotalol*
2.A Clinical Analysis of Cranioplasty Using Methyl Methacrylate.
Young Bo SHIM ; Hyung Shik HWANG ; Jong In LEE ; Sae Moon OH ; Sun Kil CHOI ; Seung Koo KANG
Journal of Korean Neurosurgical Society 1990;19(3):360-366
Cranioplasty has long been performed by many physicians with different materials from the prehistoric era. Among the materials, methyl methacrylate has been known to be the superior to any other substitutes since 1940s in biologic, chemical and physical characteristics and its availability. So the authors review 72 patients who underwent cranioplasty with methyl methacrylate at out hospital from 1985 to 1989. The clinical analyses were as follow : 1) There was male predominance and epidural hematomas, compound, comminuted depressed fractures by traffic accidents or fall down injuries were the main causes of craniectomy. 2) The location of defects was mainly frontal and/or parietal area and average size of defects was 17cm2 in plain skull film measurements. 3) The cosmetic results were satisfactory. 4) Complication rate was 6% and there was no mortality.
Accidents, Traffic
;
Hematoma
;
Humans
;
Male
;
Mortality
;
Rabeprazole
;
Skull
3.A case of Thyrotrophin(TSH)-Secreting Giant Pituitary Adenoma: Biochemical Remission with Surgery.
Jong Hyun KIM ; Seung Hoon LEE ; Moon Soo KOH ; Myung Shik LEE ; Jhin Oh LEE ; Tae Woong KANG
Journal of Korean Neurosurgical Society 1991;20(4):224-229
TSH-secreting pituitary adenomas are rare, but have been diagnosed more frequently as radiographic techniques and biochemical assays have improved. These tumors are less easily cured by surgery than are other types of pituitary adenoma because of the large size and invasive features that many attain during the delay to diagnosis. We report a case of TSH-secreting giant pituitary adenoma in which biochemical remission was achieved with surgery.
Diagnosis
;
Pituitary Neoplasms*
4.A Case of Prenatal Diagnosis of Thoracic Ectopia Cordis.
Seong Joon YOON ; Bong Shik SHIN ; Kyo Weon LEE ; Hye Sup SONG ; Jong Seul HAN ; Sung Do KIM ; Joo Seob KEUM ; Myung Sook KIM ; Tae Yun OH
Korean Journal of Obstetrics and Gynecology 1997;40(10):2317-2321
Ectopia cordis is defined as a congenital malposition of the heart partially or completely outside the thorax and often associated with sternal and congenital heart defects:surgical repair is generally unsuccessful because of the magnitude of the deformity and the associat-ed intracardiac anormalies. Four types of ectopia cordis are described : cervical, thoracic, abdominal and thoracoa- bdominal. Cervical and thoracic type are often fatal within days, because the heart is expo- sed and malformed. Abdominal type carries a better prognosis because cardiac abnormalities are less often found. The prognosis of thoraco-abdominal type mainly depends on the pre- sence of intracardiac abnormalities. We have experienced a case of thoracic ectopia cordis at 25 weeks' gestation by ultra- sonography, so present the case and the review with literature briefly.
Congenital Abnormalities
;
Ectopia Cordis*
;
Heart
;
Pregnancy
;
Prenatal Diagnosis*
;
Prognosis
;
Thorax
5.Rapid Molecular Detection of Escherichia coli O157:H7.
Hyoung Shik SHIN ; Tae Geun OH ; Jong Sung SHIN ; Jung Hoon JI ; Bo Ra SON ; Kyeong Seob SHIN
Korean Journal of Infectious Diseases 2001;33(2):97-103
BACKGROUND: Sorbitol fermenting Escherichia coli O157 were reported. And E. coli O157:H7 produce various Shiga toxin (Stx) such as Stx1, Stx2, or variants of Stx2. In this study, we tried to establish laboratory methods that detect E. coli O157:H7 quickly and precisely by analyzing sensitivity of colony hybridization test and PCR technique. METHODS: Stx1-producing E. coli ATCC 43890, Stx2-producing E. coli ATCC 43889, and Stx2vha- producing E. coli ATCC 51435 were tested. Three strains of E. coli were diluted with 0.1 g of diarrheal stools from 107 CFU to 101 CFU respectively. The stool samples were incubated overnight in MacConkey agar plates. A mean of 63 colonies were hybridized by stx1- and stx2-specific oligonucleotide probes. PCR for stx1 gene and stx2 gene was done after overnight- incubation of stool samples in the LB broth with vancomycin (6 ug/mL). Positive colonies by colony hybridization were confirmed by PCR for stx1 gene and stx2 gene. RESULTS: Colony hybridization test could detect Stx1-producing E. coli at 103 CFU per 0.1 g of stool, Stx2-producing E. coli at 105 CFU per 0.1 g of stool, and Stx2vha-producing E. coli at 104 CFU per 0.1 g of stool. PCR technique after enrichment in LB broth with vancomycin (6 ug/mL) could detect stx1-, stx2-, and stx2vha-containing E. coli at 10 CFU per 0.1 g of stool respectively. CONCLUSOIN: A combination of colony hybridization and PCR after enrichment in broth with vancomycin (6 ug/mL) is useful for the rapid and precise diagnosis of infections of Shiga toxin-producing E. coli O157:H7.
Agar
;
Diagnosis
;
Escherichia coli O157
;
Escherichia coli*
;
Escherichia*
;
Oligonucleotide Probes
;
Polymerase Chain Reaction
;
Shiga Toxin
;
Sorbitol
;
Vancomycin
6.A case of thrombotic thrombocytopenia purpura.
Seung Soo KIM ; Young Boo PARK ; Jong Youl JIN ; Hoon Kyo KIM ; Kyung Shik LEE ; Dong Jip KIM ; Jung OH ; Ki Hwa YANG
Korean Journal of Hematology 1992;27(1):175-182
No abstract available.
Purpura*
;
Thrombocytopenia*
8.Facial reanimation with masseter nerve–innervated free gracilis muscle transfer in established facial palsy patients
Tae Suk OH ; Hyung Bae KIM ; Jong Woo CHOI ; Woo Shik JEONG
Archives of Plastic Surgery 2019;46(2):122-128
BACKGROUND: The masseter nerve is a useful donor nerve for reconstruction in patients with established facial palsy, with numerous advantages including low morbidity, a strong motor impulse, high reliability, and fast reinnervation. In this study, we assessed the results of masseter nerve–innervated free gracilis muscle transfer in established facial palsy patients. METHODS: Ten patients with facial palsy who received treatment from January 2015 to January 2017 were enrolled in this study. Three patients received masseter nerve–only free gracilis transfer, and seven received double-innervated free gracilis transfer (masseter nerve and a cross-face nerve graft). Patients were evaluated using the Facial Assessment by Computer Evaluation software (FACEgram) to quantify oral commissure excursion and symmetry at rest and when smiling after muscle transfer. RESULTS: The mean time between surgery and initial movement was roughly 167.7 days. A statistically significant increase in excursion at rest and when smiling was seen after muscle transfer. There was a significant increase in the distance of oral commissure excursion at rest and when smiling. A statistically significant increase was observed in symmetry when smiling. Terzis’ functional and aesthetic grading scores showed significant improvements postoperatively. CONCLUSIONS: Masseter nerve innervation is a good option with many uses in in established facial palsy patients. For some conditions, it is the first-line treatment. Free gracilis muscle transfer using the masseter nerve has excellent results with good symmetry and an effective degree of recovery.
Facial Nerve
;
Facial Paralysis
;
Free Tissue Flaps
;
Humans
;
Smiling
;
Tissue Donors
9.First detection of West Nile virus in domestic pigeon in Korea.
C Yoon KIM ; Hanseul OH ; Juha SONG ; Moonsuk HUR ; Jae Hwa SUH ; Weon Hwa JHEONG ; Jong Taek KIM ; Hong Shik OH ; Jae Hak PARK
Journal of Veterinary Science 2016;17(4):587-589
West Nile virus (WNV) is a mosquito-borne zoonotic pathogen that has spread throughout Europe and the United States. Recently, WNV spread to East and Southeast Asia, and great efforts have been made in South Korea to prevent the spread of WNV from neighboring countries. In this study, we diagnosed the first case of WNV in pigeons (Columba livia domestica) residing in cities using a competitive enzyme-linked immunosorbent assay and confirmed it with nested reverse transcription polymerase chain reaction analysis and sequencing. This is the first report to provide convincing evidence that WNV is present within South Korea.
Asia, Southeastern
;
Columbidae*
;
Enzyme-Linked Immunosorbent Assay
;
Europe
;
Korea*
;
Polymerase Chain Reaction
;
Reverse Transcription
;
United States
;
West Nile virus*
10.Prevalence of Measles, Rubella and Varicella-Zoster Antibodies in Hospital Personnel.
Hyoung Shik SHIN ; Hyang Soon OH ; Sung Min KIM ; Nam Joong KIM ; Hee Jung CHOI ; Myoung Don OH ; Hwan Jong LEE ; Kang Won CHOE
Korean Journal of Infectious Diseases 1997;29(1):29-32
BACKGROUND: To assess the risk of hospital outbreak and to guide immunization policy, seroprevalences of antibody to measles, rubella, and varicella-zoster were determined in hospital personnel. METHODS: A cross-sectional study of 290 workers in Seoul National University Hospital was conducted in June 1995. IgG antibody status was determined with commercially available enzyme linked immunosorbent assay (Behring Enzygnost; IgG kit). RESULTS: Seropositive rates of measles, rubella and varicella-zoster were 95.6%, 87.9% and 96.2%, respectively. There was no statistical difference in seropositive rate according to historical information. CONCLUSION: These results suggest potential for hospital outbreak of measles or varicella-zoster, especially of rubella. Immunization policy will be needed in hospital personnel.
Antibodies*
;
Cross-Sectional Studies
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Immunization
;
Immunoglobulin G
;
Measles*
;
Personnel, Hospital*
;
Prevalence*
;
Rubella*
;
Seoul
;
Seroepidemiologic Studies