1.Management of tracheal stenosis: a retrospective clinical study.
Jong Ouck CHOI ; Kwang Yoon JUNG ; Jong Seon YOO ; Hong Kyun YOO
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):143-147
No abstract available.
Retrospective Studies*
;
Tracheal Stenosis*
2.Ultrastructural Changes of the Bile Canaliculi after Common Bile Duct Ligation.
Kook Seon YOO ; Suk Hee LEE ; Hee Kyung PARK ; Chang Ho CHO ; Jong Min CHAE
Korean Journal of Pathology 1996;30(3):175-183
The purpose of this study was to investigate the morphologic changes of the bile canaliculi and its associated structures of the liver induced by common bile duct ligation(CBDL) in the rat. The canalicular surface and lateral surface of the dry-fractured hepatocytes was studied with scanning electron microscopy at 1~6 weeks post ligation. The first week after CBDL, the bile canaliculi were dilated. The microvilli were increased in number and the lumens contained granular materials After 2 weeks or more, the bile canaliculi were dilated to a variable degree, and with irregularity, measuring from 1.5 to 5 micrometer in diameter, and in the advanced stage, the canaliculi showed blunting and the disappearance of microvilli. Some canaliculi had sprouting side branches. At 4~6 weeks post-ligation, the lateral surface of the hepatocytes also showed some irregularity and a tortuous appearance, and numerous small sized microvillous projections were formed. The tubular structures of the proliferated SER distributed adjacent to the lateral surface of the hepatocytes, and the direct connection of a tubular structure and the cytoplasmic membrane was observed. These results suggest that the deformity and loss of microvilli of bile canaliculi reflect the disturbance of bile secretion from the hepatocytes. And prolonged obstruction of bile flow may result in bile excretion via the lateral surface of hepatocytes.
Rats
;
Animals
3.Active Bleeding Acre During Surgical Extraction of Mandibular Third Molar: Report of Two Cases.
Jong Bae KIM ; Jae Ha YOO ; Seon Jae MOON ; Seung Beom KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2001;27(6):560-564
The experienced surgeon can be surprised & challenged by the hazards of active bleeding during oral & maxillofacial surgical procedure, because of alterations in the surgical anatomy, bleeding disorders and surgical intervention of infected tissues. This is a report of two cases of active bleeding during surgical extraction of mandibular third molar, that had the pericoronitis, osteitis and adjacent neurovascular bundle in its apex. When the abrupt active bleeding was occurred during surgical extraction of mandibular third molar, pressure packing by hemostatic agent(bone wax) & wet gauze biting were applied into the extraction socket during 30 minutes. After 30 minutes, the wound was explored about the bleeding and active bleeding was then continued. In spite of repeated bleeding control method of the pressure dressing, the marked hemorrhage was generated continuously. Therefore, the author decised the bleeding as immediately uncontrollable hemorrhage and the pressure dressing was again applied for the more longer duration without wound closure. After 3 days, the pressure dressing was removed and iodoform gauze drainge was then established without the bleeding. The drain was changed as the interval of 3~5 days for prevention of infection & secondary hemorrhage and relatively good wound healing was then resulted in 6 weeks.
Bandages
;
Hemorrhage*
;
Molar, Third*
;
Osteitis
;
Pericoronitis
;
Wound Healing
;
Wounds and Injuries
4.A Case of pulmonary lymphangioleiomyomatosis developed in tuberous sclerosis with renal angiomyolipoma.
Myung Im KIM ; Hong Mo KANG ; Ho Jong LEE ; Yong Ho KOH ; Yong Seon CHO ; Jee Hong YOO
Tuberculosis and Respiratory Diseases 2000;48(5):788-793
Tuberous sclerosis is a rare hereditary anomaly of variable penetrance characterized by mental retardation, epilepsy, and adenoma sebaceum. Pulmonary involvement is uncommon, but, when involve by tuberous sclerosis, it shows characteristic reticulonodular infiltration and cystic changes. Lymphangioleiomyomatosis is a rare disease of unknown cause that affects women of reproductive age. It is characterized by progressive proliferation of smooth muscle in the lung. We experienced one case of pulmonary lymphangioleiomyomatosis associated with tuberous sclerosis in a 26-year-old female patient. This case is reported with a brief of the literature.
Adult
;
Angiomyolipoma*
;
Epilepsy
;
Female
;
Humans
;
Intellectual Disability
;
Lung
;
Lymphangioleiomyomatosis*
;
Muscle, Smooth
;
Penetrance
;
Rare Diseases
;
Tuberous Sclerosis*
5.The Effects of Steroids and Nonsteroidal Antiinflammatory Agents on Proliferation of Human Ocular Fibroblast.
Jong Soo LEE ; Wook JUNG ; Young Rak CHOI ; Yoo Seon KIM
Journal of the Korean Ophthalmological Society 1999;40(6):1496-1502
Corticosteroid, 5-fluorouracil and Mitomycin C(MMC) have been used to suppress proliferation of subconjunctival connective tissue. However, the various complication and undesirable side effects associated with the use of these drugs have prompted the search for alternative drugs with less toxicity. In present study, I have evaluated the effect of corticosteroid(dexamethsone sodium phophate), cyclooxygenase inhibitor(diclofenac sodium) and lipoxygenase inhibitor(nordihydroguaratic acid, NDGA) to inhibit human pterygial fibroblast proliferation in tissue culture. Human pterygial fibroblast were cultured and exposed to various concentration of each drug for 1, 2 and 3 days. Cell viability was measured using MTT assay. There was no different in antiproliferative activity between nonsteroidal antiinflammatory agents(NSAIDs) and steroid. Dexamethasone caused inhibition of proliferation with LD 50 of 0.5mM by day 2, NDGA of 0.5mM by day 3 and diclofenac sodium of 1.0mM by day 3. These results suggest that NSAIDs may be useful as both antiproliferative and less toxicity agents.
Anti-Inflammatory Agents, Non-Steroidal*
;
Cell Survival
;
Connective Tissue
;
Dexamethasone
;
Diclofenac
;
Fibroblasts*
;
Fluorouracil
;
Humans*
;
Lipoxygenase
;
Mitomycin
;
Prostaglandin-Endoperoxide Synthases
;
Sodium
;
Steroids*
6.The Effect of Mitomycine C (MMC) on Inhibition of Pterygial Fibroblast Proliferation.
Jong Soo LEE ; Do Young JUNG ; Yoo Seon KIM
Journal of the Korean Ophthalmological Society 1998;39(7):1410-1416
The purpose of this study is to investigate that the biological effect of mitomycin C(MMC) in cellular metabolic activity and morphological change on the ptreygium fibroblast in vitro by MMC concentration and duration of exposure used clinically. Human pterygial fibroblasts were exposed for threeminute and five-minute to MMC 0.002%, 0.004%, 0.01%, 0.02%, 0.04%, and DMEM(control). MTT based colorimetric assay was performed to assess the metabilic activity, inhibition of fibroblast proliferation on the MMC concentration and exposure time. The higher the concentration of MMC, and longer the duration of exposure time, the absorbance of spectrometer are decreased. The metabolic activity of fibroblasts were inhibited by 50% at least only over MMC 0.02% for five-minute expoure time. In histological findings, the higher the concentration and longer the duration of MMC exposure time, the enlargement of many mitochondira and rough endoplasmic reticulum without nuclear damage were more distinctly appeared. Especially, the ptergial fibroblast has more severe cytoplasmic damage at a five-minute exposure to MMC 0.02% than a three-minute exposure to MMC 0.04%. For inhibition of fibroblast proliferation, in case of using MMC should be at least over 0.02% concentration for five-minute exposure time. Arthors think that the experimental and clinical research on the duration of MMC exposure time as well as the concentration MMC, should be need to evaluate the effect on inhibition of cellular proliferation.
Cell Proliferation
;
Cytoplasm
;
Endoplasmic Reticulum, Rough
;
Fibroblasts*
;
Humans
;
Mitomycin*
7.Effect Of Drainage Via Dental Root Canal & Extraction Wound In The Unconscious Patient With Continuouns Self-Bite Wounds.
Jong Bae KIM ; Jae Ha YOO ; Byung Ho CHOI ; Seon Jae MOON
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2001;27(5):457-463
In the unconscious patient with general muscle rigidity, the natural teeth can be luxated and then bite wounds may be occurred around lip, owing to the pathologic involuntary self-biting habit. If the forceful biting is generated continuously, the teeth may be avulsed and aspirated into the aerodigestive tract with the infection of biting wound. For the prevention of pulmonary aspiration of the teeth and wound infection, the biting teeth should be cared before the fact. The authors treated the teeth as endodontic drainage with removal of the crown or iodoform gauze drainage into the socket with extraction of the teeth. The prognosis was more favorable without biting wounds.
Crowns
;
Dental Pulp Cavity*
;
Drainage*
;
Humans
;
Lip
;
Muscle Rigidity
;
Prognosis
;
Tooth
;
Wound Infection
;
Wounds and Injuries*
8.A Clinical study on the dental emergency patients of k-country hospital of medical college during recent 8 years
Jae Ha YOO ; Jong Bae KIM ; Tae Woo KIM ; Seon Jae MOON ; Hyuk Chan KWON ; Seung Beom KIM
Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons 2001;23(6):523-532
No abstract available.
Emergencies
;
Humans
9.A clinical study of uvulopalatopharyngoplasty for sleep apneasyndrome.
Sung Min JIN ; Jong Ouck CHOI ; Jong Seon YOU ; Heung Eog CHA ; Chan Woo KIM ; Hyun Ho LIM ; Hong Kyun YOO
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(4):756-761
No abstract available.
10.Prediction of successful caudal epidural injection using color Doppler ultrasonography in the paramedian sagittal oblique view of the lumbosacral spine
Seon Woo YOO ; Min-Jong KI ; A Ram DOO ; Cheol Jong WOO ; Ye Sull KIM ; Ji-Seon SON
The Korean Journal of Pain 2021;34(3):339-345
Background:
Ultrasound-guided caudal epidural injection (CEI) is limited in that it cannot confirm drug distribution at the target site without fluoroscopy. We hypothesized that visualization of solution flow through the inter-laminar space of the lumbosacral spine using color Doppler ultrasound alone would allow for confirmation of drug distribution. Therefore, we aimed to prospectively evaluate the usefulness of this method by comparing the color Doppler image in the paramedian sagittal oblique view of the lumbosacral spine (LS-PSOV) with the distribution of the contrast medium observed during fluoroscopy.
Methods:
Sixty-five patients received a 10-mL CEI of solution containing contrast medium under ultrasound guidance. During injection, flow was observed in the LSPSOV using color Doppler ultrasonography, following which it was confirmed using fluoroscopy. The presence of contrast image at L5-S1 on fluoroscopy was defined as “successful CEI.” We then calculated prediction accuracy for successful CEI using color Doppler ultrasonography in the LS-PSOV. We also investigated the correlation between the distribution levels measured via color Doppler and fluoroscopy.
Results:
Prediction accuracy with color Doppler ultrasonography was 96.9%. The sensitivity, specificity, positive predictive value, and negative predictive value were 96.7%, 100%, 100%, and 60.0%, respectively. In 52 of 65 patients (80%), the highest level at which contrast image was observed was the same for both color Doppler ultrasonography and fluoroscopy.
Conclusions
Our findings demonstrate that color Doppler ultrasonography in the LS-PSOV is a new method for determining whether a drug solution reaches the lumbosacral region (i.e., the main target level) without the need for fluoroscopy.