2.Infantile Acute Hemorrhagic Edema of the Skin.
Jong Gu KIM ; Jae Hoon PARK ; Seok Don PARK
Korean Journal of Dermatology 1995;33(6):1143-1147
Infantile acute hemorrhagic edema of the skin(IAHE) is a benign disease which affects infants between 4 months and 2 years of age and is characterized by palpable ecchymotic purpura and edema on the limb and face. We report a typical case of IAHE, which was presenting a cockade, annular, reticulated, and iris-like purpura and edema on the face and extremities in a 19-month-old male infant. We consider it to be a new disease category because its characteristics different markedly from HenochSchoenlein purpura in several clinical and histopathologic findings.
Edema*
;
Extremities
;
Humans
;
Infant
;
Male
;
Purpura
;
Skin*
3.A Case of Reiter' s syndrome.
Jae Hoon PARK ; Jong Ku KIM ; Seok Don PARK
Korean Journal of Dermatology 1995;33(3):526-533
Reiters syndrome is classically described as the triad of urethritis, coijuctivitis, and arthritis along with the skin manifestation. of keratodermia blenorrhagica, circinate b lanitis and oral ulcetation. Since arthritis is now recognized as the only consistent component, iricr nplete forms consisting of characteristic arthritis associeited with one or more of these features and of dysentery are common, We reported a 48-year-old male who presented with a 3 years histor of significant arthralgia and psoriasiforrn skin involvemeni. He had neither an episode of dysentery not, history of sexual exposure before the onset of symptomes. Showed a correlation with the HLAB 7 tialotype. C-reactive protein levels were significantly elevated. He was treared with corticosteroid, pcycline, methotrexate and indomethacin for about 3 months resulting favorable improvement.
Arthralgia
;
Arthritis
;
C-Reactive Protein
;
Dysentery
;
HLA-B27 Antigen
;
Humans
;
Indomethacin
;
Male
;
Methotrexate
;
Middle Aged
;
Skin
;
Skin Manifestations
;
Urethritis
4.The Effectiveness of Questionnaire Utilized for Screening Noise Induced Hearing Loss.
Jae Seok SONG ; Byoung Soo CHOI ; Jong Uk WON ; Jae Hoon ROH
Korean Journal of Occupational and Environmental Medicine 2000;12(4):473-482
OBJECTIVES: This study was performed to investigate the effectiveness of the questionnaire. METHODS: Workers'health examination records, work environment record, and questionnaires of selected industries as samples were analysed using logistic regression analysis and discrimination analysis Results'Cases of bearing impairment (Dl+C) as dependent variables, and age, work duration and level of environmental noise as independent variables were selected for multiple unconditional logistic regression analysis. Odds ratio was 4.04 in hearing difficulty, 2.78 in tlnnitus and 1.08 in age. In the second analysis Noise induced hearing loss is selected as dependent variable. The OR in hearing difficulty was 3.67(95 % C.1. : 1.61 8.61), and was 1.09(95 % C.1. : 1.05-1.14) in age. Conditionnal multlple logistic regression analysis was performed. In hearing impairment as dependent variable, the OR of age was 1.02(95 % C.1. : 1.00-1.04) and other variables were not significant. However, NIHL as dependent, the OR of hearing difficulty was 4.57(95 % C.1. : 1.43-14.67). According to multiple logistic regression adopting each items of questionnaire as dependent variable, the only item of hearing difficulty showed significant difference with hearing ability. The discrimination analysis was performed with the class variable of hearing impairment, and discrimination variables of age, work duration, and environment noise level. The sensitivity of 59 %, and specificity of 88 %, and average error count of 23 % were obtained. When the numbers of items answered in questionnaire were assumed as the parameter of judgement for noise induced hearing loss (NIHL), the highest sensitivity and specificity were 33.5% and 49.0% in cases of more than two items answered. CONCLUSIONS: The development of items that is simple and discriminative mainly consisted of chronic and specific diseases related items is needed. Computerization for newly developed items might be needed to establish effective surveillance system for NIHL in the future.
Discrimination (Psychology)
;
Hearing Loss*
;
Hearing*
;
Logistic Models
;
Mass Screening*
;
Noise*
;
Odds Ratio
;
Questionnaires*
;
Sensitivity and Specificity
5.Expression of Neuron Specific Enolase, Chromogranin, and Synaptophysin in Peripheral Neuroblastic Tumors.
Hyung Seok KIM ; Jae Ha HWANG ; Jong Jae JUNG ; Min Cheol LEE
Korean Journal of Pathology 2000;34(8):588-596
The presence and distribution of pan-neuroendocrine markers such as neuron-specific enolase (NSE), chromogranin (CG), and synaptophysin (SYP) were investigated by immunohistochemistry in 15 cases of neuroblastic tumors, including four cases of neuroblastomas, six cases of ganglioneuroblastomas, and five cases of ganglioneuromas. Three cases of normal sympathetic ganglion were used for the normal control group. NSE was observed in all cases and both in ganglion cells and in neuropils. NSE was detected not only in the majority of the neuroblasts showing signs of differentiation, but also in some poorly differentiated neuroblasts. All cases of neuroblastic tumors were positive for CG, however, some variability of staining intensity and distribution patterns were noted. CG was found mainly in differentiated neuroblasts with enlarged cytoplasm and nuclei along the periphery of the perikaria, and was also found in the perinuclear regions of some undifferentiated cells. SYP was positive in 9 of 11 cases. In all of the 9 cases, SYP was detected in some differentiating neuroblasts and differentiated neuroblasts, as well as the mature ganglion cells. However, it has scarcely stained in dot or granular pattern. Two CG-negative tumors were also negative for SYP. Our data indicate that antibodies against NSE and CG are helpful as a diagnostic aid for neuroblastic tumors.
Antibodies
;
Cytoplasm
;
Ganglia, Sympathetic
;
Ganglion Cysts
;
Ganglioneuroblastoma
;
Ganglioneuroma
;
Immunohistochemistry
;
Neuroblastoma
;
Neurons*
;
Neuropil
;
Phosphopyruvate Hydratase*
;
Synaptophysin*
6.Risk Factors of Dislocation Occurring after Acetabular Component Revision.
Yoo Seong SEO ; Jae Wan SOH ; Park JONG-SEOK ; Soo Jae YIM ; Byung Ill LEE
Journal of the Korean Hip Society 2006;18(3):97-102
Purpose: To analyze the causes and to prevent dislocations of the hip joint that occur in patients who underwent revisions of total hip arthroplasties by changing only the polyethylene liners and femoral heads, subsequent to primary total hip arthroplasties. Materials and Methods: We evaluated 28 patients who underwent acetabular component revisions of total hip arthroplasties subsequent to primary total hip arthroplasties. The average age of the patients was 55 years old and all 28 patients had operations through the posterolateral approach. In 17 of the cases, the acetabular cups, polyethylene liners, and femoral heads were changed; in 10 cases, just the polyethylene liners and femoral heads were changed; and in 1 case, only the polyethylene liner was changed. Results: We observed 7 cases of hip dislocations that occurred among a total of 28 cases after revisions of total hip arthroplasties. In all 7 cases, the polyethylene liners and femoral heads were changed, but not the acetabular cups. In additional, in all 7 cases of dislocation, the patients were non-compliant and started weight-bearing prematurely after revisions of the total hip arthroplasties Conclusion: We observed new dislocations in the 7 cases in which the polyethylene liners and femoral heads were changed. The main reasons were inadequate soft tissue tension and hip joint laxity. Therefore, it is necessary to increase the neck length, use elevated rim polyethylene liners, readjust the acetabular cups to their optimal positions, and apply hip abduction braces to patients early after revision of total hip arthroplasties in order to lessen the danger of dislocations.
Acetabulum*
;
Arthroplasty
;
Braces
;
Dislocations*
;
Head
;
Hip
;
Hip Dislocation
;
Hip Joint
;
Humans
;
Neck
;
Polyethylene
;
Risk Factors*
;
Weight-Bearing
7.Congenital Smooth Muscle Hamartoma: a Patchy Follicular Variant.
Soon Baek KWON ; Seok Jong LEE ; Do Won KIM ; Jae Bok JUN
Annals of Dermatology 2000;12(3):231-234
Cutaneous smooth muscle hamartomas are benign proliferations of smooth muscle bundles within the dermis. They can be congenital or acquired, and most cases are congenital. Congenital smooth muscle hamartomas (CSMHs) usually manifest at birth as well-circumscribed, frequently hypertrichotic, hyperpigmented or skin-colored patches or plaques on trunk or extremities. We report a case of CSMH in a 10 year-old girl, who showed a localized skin-colored patch showing prominent follicular papules on the lateral aspect of her right upper arm, which were found at birth. There was no hypertrichosis and the pseudo-Darier sign was negative. This patchy follicular variant is the less common clinical type of the disease.
Arm
;
Dermis
;
Extremities
;
Female
;
Hamartoma*
;
Humans
;
Hypertrichosis
;
Muscle, Smooth*
;
Parturition
8.The Role K+ channel and the Effect of K+ channel Opener in the Relaxation of Vaginal Smooth Muscle.
Hong Seok PARK ; Heung Jae PARK ; Du Geon MOON ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Urology 2000;41(8):968-975
No abstract available.
Muscle, Smooth*
;
Relaxation*
9.Two Cases of Venous Hemangioma.
Soon Baek KWON ; Hyun Joo LEE ; Seok Jong LEE ; Jae Bok JUN ; Eun Kyoung KWACK
Korean Journal of Dermatology 1999;37(3):410-412
Venous hemangioma is a vascular tumor that has been reported by such diverse names as; "cirsoid aneurysm", "arteriovenous hemangioma", "acral arteriovenous tumor" according to the author's opinions of its origin and histopathologic classification. It is benign and rarely biopsied, and it is also rarely reported in dermatology literature. We present two cases of venous hemangioma. The first case was a 64-year-old man who was presented with an elliptical dark-red plaque with overlying several grouped papules on the left periorbital area which had been present for 7 years. The second case was a 56-year-old man who was presented with a single red papule on the right postauricular area which had been present for 4 months. Histopathologically, there were a well-circumscribed proliferation of thick-walled muscle-containing blood vessels in the dermis. Intermingled with the thick-walled blood vessels, there were also thin-walled dilated blood vessels. In both cases, the thick-walled blood vessels resembled arteries, but they lacked elastic fibers on the Verhoeff van Gieson stain.
Arteries
;
Blood Vessels
;
Classification
;
Dermatology
;
Dermis
;
Elastic Tissue
;
Hemangioma*
;
Humans
;
Middle Aged
10.Extensive Condyloma Acuminatum in a NIDDM Patient.
Sun Wook HWANG ; Jong Jae JUNG ; Seok Mo KIM
Korean Journal of Dermatology 1999;37(12):1798-1802
A 20 year old woman with noninsulin-dependent diabetes mellitus (NIDDM) developed an extensive warty and focally cauliflower like mass located at anogenital area. Its histopathologic study and in situ DNA hybridization revealed this lesion an ordinary condyloma acuminatum without large bulbous downward proliferation of which HPV type was 6 and/or 11. The mass lesion was successfully treated by excision and electrodesiccation under spinal anesthesia. Intermittent recurrence of several papular condylomata acuminata was observed during a follow up period of 6 months, which were easily cured by podophylline application on each occasion.
Anesthesia, Spinal
;
Brassica
;
Condylomata Acuminata
;
Diabetes Mellitus, Type 2*
;
DNA
;
Female
;
Follow-Up Studies
;
Humans
;
Podophyllin
;
Recurrence
;
Young Adult