2.Comparative Study for METHODSfor Diagnosing Onychomycosis.
Korean Journal of Dermatology 1995;33(3):467-473
BACKGROUND: Onychomycosis is very common nail problem, so an in xpensive, quick and sensitive test is essential for screening nail specimens. Recently, there is a report of new method for diagnosing onychomycosis u.;ing KOH treated nail clippings which vri then crushed and finally stained with periodic acid-Schifft(PAS) stain (KONCPA). OBJECTIVE: We evaluate the susefulness of the new methods using KOH treated nail clippings and nail debris which were then crushed and finally stained with FS (KONPA) or chlorazol black E(KONBE), for the diagriosis of onychomycosis. METHODS: We compare different methods for diagnosing onychonycisis such as KOH stains, fungal cultures, histologic evaluation, SEM, KONCPA, KONBE, and KOHJPA. RESULTS: KONPA was proved to be more effective indentifying uiigal hyphae in comparison with conventional KOH nail scraping preparation, fungal culture, and FONBE. The positive rates of each method were 74%, 46%, 43%, and 63%, respectively. Also, KENPA proved to be more rapid and easy to perform in cotnparison to the histologic evaluation of tiail clippings and SEM. CONCLUSION: KONPA is a sensitive, quick, and readily available teled for use in clinical settings in cases that are highy siispected to be onychomycosis clinicaly, but show negative results using conventional methods
Coloring Agents
;
Hyphae
;
Mass Screening
;
Onychomycosis*
3.Clinical Study on Antihypertensive Effect of Verapamil.
Korean Circulation Journal 1988;18(1):153-158
The antihypertensive effect of verapamil, a calcium channel blocker, was studied in 12 cases of essential hypertension (mean age 49, range 24-64). After 6 weeks administration (80-160mg t.i.d.), the following results were obtained : 1) Before medication, average systolic and diastolic blood pressure was 176.3/108.6mmHg. After completion of therapy, blood presure fell significantly down to 154.8/94.2mmHg (p<0.01). 2) Heart rate decreased slightly from average 74.3 per minute prior to medication to 69.3 per minute at the end of study (p<0.01). 3) Side effects, among which constipation was most common, were mild and did not compel any patient to diacontinue therapy. In conclusion, verapamil seems to be a safe and effective first-line drug for hypertension along with diuretics or beta blockers.
Blood Pressure
;
Calcium Channels
;
Constipation
;
Diuretics
;
Heart Rate
;
Humans
;
Hypertension
;
Verapamil*
4.Metastatic Large Cell Neuroendocrine Carcinoma of the Lung Mimicking a Merkel Cell Carcinoma.
Jong Seo LEE ; Won Soon CHUNG ; Dong Hyun KIM ; Jong Seo LEE ; Soo Chan KIM
Annals of Dermatology 2002;14(2):121-123
Large cell neuroendocrine carcinoma (LCNEC) of the lung is a newly recognized entity of pulmonary neuroendocrine carcinoma. Histologically, it is very difficult to differentiate LCNEC from other pulmonary carcinomas and the prognosis is significantly poor. The cutaneous metastasis of LCNEC of the lung shares some features with Merkel cell carcinoma of the skin in light microscopy and yet it is negatively stained with cytokeratin 20. We report a case of cutaneous metastasis of LCNEC of the lung, previously misdiagnosed as squamous cell carcinoma. Our patient showed a poor response to the chemotherapy and also revealed a brain metastasis on follow-up brain CT scan.
Brain
;
Carcinoma, Merkel Cell*
;
Carcinoma, Neuroendocrine*
;
Carcinoma, Squamous Cell
;
Drug Therapy
;
Follow-Up Studies
;
Humans
;
Keratin-20
;
Lung*
;
Microscopy
;
Neoplasm Metastasis
;
Prognosis
;
Skin
;
Tomography, X-Ray Computed
5.A Case of Oil Granuloma Developed after Application of Squalene on Both Eyelids.
Jong Seo LEE ; Kwang Hoon LEE ; Soo Il CHUN
Korean Journal of Dermatology 1995;33(1):135-139
Oil granuloma develops mainly after injection of oil substances such as paraffin, silicone, etc, but there have been reports of oil granuloma after topical application of lipid substance to the body. A 22-year-old woman developed oil granuloma after the application of squalene on both lower eye-lids. Histopathologic findings ahowed acanthosis and dyskeratosis of the hair follicles. Lipid suketances staining with oil-red-O stain were found mainly on the hair follicles. and partly on the epidermis. We report a case of oil grinulorna caused by squalerie that may have penetrated through the hair follicles and partly through the epidermis resulting in chronic granulous changes in the dermis.
Dermis
;
Epidermis
;
Eyelids*
;
Female
;
Granuloma*
;
Hair Follicle
;
Humans
;
Paraffin
;
Silicones
;
Squalene*
;
Young Adult
7.Clinical analysis on hepatic surgery for patients with primary hepatic malignant tumor.
Dong Goo KIM ; Jong Seo LEE ; In Chul KIM
Journal of the Korean Surgical Society 1992;43(4):529-539
No abstract available.
Humans
8.A Clinical Observation on Fulminant Hepatitis in Children.
Hoan Jong LEE ; Jeong Kee SEO ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1987;30(4):406-415
No abstract available.
Child*
;
Hepatitis*
;
Humans
9.Preliminary Study of Vaginal Cones:A conservative Method of Treating Stress Incontinence.
You Sik LEE ; Jong Hyun KIM ; Ju Tae SEO
Journal of the Korean Continence Society 1997;1(1):60-60
No abstract available.
10.Biofeedback and Functional Electric Stimulation in the Treatment of Genuine Stress Incontinence.
Jong Hyun KIM ; Ju Tae SEO ; You Sik LEE
Journal of the Korean Continence Society 1997;1(1):59-59
No abstract available.
Biofeedback, Psychology*
;
Electric Stimulation*