No abstract available.
Bronchopulmonary Sequestration*

No abstract available.
Heart Defects, Congenital* ; Plasma*

To evaluate the corneal epithelial barrier after exposure to Benzalkonium chloride(BAC) or commonly used eyedrops, we measured corneal uptake of 5, 6-carboxyfluorescein(CF) applied to the corneal epithelium of the albino rabbits(70 eyes). Four BAC solutions (0.001 %, 0.01%, 0.05%, 0.1 %), ofloxacin solutions (Tarivid(R), Octacin(R), Ofloxacin(R)), fluorometholone solutions(Fumelon(R), Fluorometholone(R)), artificial tear solutions (Tears Naturale(R), Tears Naturale II(R), Tears naturale Free(R)) were evaluated. Balanced salt solution was used in control group. As the concentration of BAC increased, corneal epithelial permeability increased. In Octacin(R) group, corneal epithelial permeability increased about 5 times more than in Tarivid(R) and Ofloxacin(R) groups (p<0.01). Fluorometholone(R) group showed less increased permeability than in Fumelon group, but there was no statistical difference between them(p>0.05). Tears Naturale(R) showed the highest permeability among artificial tear solutions and there were no statistical differences between Tears Naturale II(R), Tears Naturale Free(R) and control group(p>0.1). This study showed that the higher concentration of BAC, the more damages to the barrier function of the corneal epithelium, and that clincally used eyedrops containing BAC made destructive influences on the corneal epithelial integrity.
Benzalkonium Compounds* ; Epithelium, Corneal ; Fluorometholone ; Ofloxacin ; Ophthalmic Solutions* ; Permeability ; Tears

No abstract available.
Esophageal Atresia* ; Tracheoesophageal Fistula*

No abstract available.
Immunoglobulins* ; Lactoglobulins* ; Milk*

The practice of adding antibiotics to anterior chamber-irrigating solutions as a prophylaxis for endophthalmitis has been used recently.To evaluate corneal endothelial toxicity of different concentrations of antibiotics in irrigating solutions, rabbit corneas were mounted in the in-vitro dual-cham-bered specular microscope and the endothelium was perfused with glu-tathione-bicarbonate Ringer solution (GBR)containing antibiotics such as ofloxacin, vancomycin or cephapirin.Mate corneas were perfused with GBR alone and used as control.Corneal thickness was measured every 15 minutes throughout the perfusion period and corneal swelling rates were calculated. Swelling rates of corneas perfused with 2 /ml or 5 /ml ofloxacin, 60 microgram/ml or1 0 /ml vancomycin, and 10 /ml or 20 /ml cephapirin was not significantly different from that of control (p>0.05).The corneas perfused with 20 /ml cephapirin deswelled probably due to high osmolarity of it.Perfusion with 10 /ml vancomycin plus 5 /ml ofloxacin did not show corneal swelling compared to control (p>0.05).This study demonstrates that the above concentra-tions of antibiotics in irrigating solutions do not affect endothelial function of the rabbit cornea.
Anti-Bacterial Agents* ; Cephapirin ; Cornea ; Endophthalmitis ; Endothelium ; Ofloxacin ; Osmolar Concentration ; Perfusion ; Vancomycin

Hypertensive encephalopathy is an acute clinical syndrome that shows central nerve dysfunction with sudden and marked elevation in blood pressure. But its pathophysiologic mechanisms, clinical courses and prognosis are still not clear. In order to study clinical manifestations and response to treatment in patients with hypertensive encephalopathy, we reviewed 45 patients with hypertensive encephalopathy who were admitted in Dept. of Internal Medicine, National Medical Center, from January 1975 to December 1984. The following results were obtained: 1) The ratio of male to female was 1.1:1. The peak age of incidence was in the 6th and 7th decade with mean age of 57.5 years. 2) Among 45 patients, only 29 had known history of hypertension and the average duration of hypertension was 8.1+/-3.6 years. 3) The most common sympotm was severe headache (68.9%). And altered consciousness, nausea and/or vomiting, focal neurologic signs and visual disturbance were also common symptoms in decreasing order of frequency. 4) Funduscopic examination showed hypertensive retinopathy in 20 of 24 (91.7%) patients and lumbar puncture revealed increased CSF pressure in 12 of 20 (60%) patients. 5) In most patients, the mean interval to symptomatic improvement was 2.1 days after administration of anti hypertensive agents, but in 6 patients with initial mean arterial blood pressure above 170mmHg, 4 patients showed delayed response and 2 patients were expired.
Antihypertensive Agents ; Arterial Pressure ; Blood Pressure ; Consciousness ; Female ; Headache ; Humans ; Hypertension ; Hypertensive Encephalopathy* ; Hypertensive Retinopathy ; Incidence ; Internal Medicine ; Male ; Nausea ; Neurologic Manifestations ; Prognosis ; Spinal Puncture ; Vomiting

Aspergillus is a relatively uncommon and saprophytic, ubiquitous fungus that is normally not pathogenic in human. Usually arising from the paranasal sinuses, it may present in manifold ways within the orbit. Some severe presentation, such as cerebral involvement, may lead to fatal outcome in immunocompromised patients. As a result, when it occurs it requires early recognition, aggressive surgical management, and prolonged antifungal therapy. Recently authors experienced a case of sino-orbital-cerebral Aspergillosis in a healthy woman. Therefore we report our case with a review of related literature.
Aspergillosis* ; Aspergillus ; Fatal Outcome ; Female ; Fungi ; Humans ; Immunocompromised Host ; Orbit ; Paranasal Sinuses

No abstract available.
Child* ; Humans ; Immunoglobulins ; Infant, Newborn* ; Lactoglobulins ; Milk Proteins* ; Milk* ; Mothers* ; Postpartum Period*

BACKGROUND: The risk for a hand injury was increased according to industrial structure and lifestyle change. This study investigated the post traumatic stress (PTS) and related factors in some hand replantation patients. METHODS: Total 150 hand replantation patients in one hospital were selected using convenience sampling methods. General characteristics of patients, characteristics of injured hand, self-esteem and PTS were collected using self-reported questionnaires. And clinical characteristics of injured hand were obtained from a review of medical records. Descriptive analysis, t-test, ANOVA and multiple regression analysis were performed to determine the associated factors with the score of PTS. RESULTS: Among 150 patients, 80% were male and 94% had a job. The mean score of PTS was 22.2±16.9. In simple analysis, PTS score were associated with smoking status, injury day of the week, pain score and self-esteem. Finally, the subjects who injured in weekdays had significantly higher PTS score compared to subjects who injured in weekend (β=0.185, P=0.021) and pain score was positively associated with PTS score (β=0.181, P=0.027) in multiple regression analysis. CONCLUSIONS: Injury day of the week and pain score were associated with PTS score in some hand replantation patients. Considering these results will help to management and improve quality of life of hand replantation patients.
Amputation ; Hand Injuries ; Hand* ; Humans ; Life Style ; Male ; Medical Records ; Quality of Life ; Replantation* ; Risk Factors ; Smoke ; Smoking