1.Clinical Analysis of Intracranial Tuberculomas.
Soon Phil PARK ; Jong Hyun CHOI ; Jong Oung DOH
Journal of Korean Neurosurgical Society 1984;13(3):425-431
We have experienced 10 cases of intracranial tuberculoma which were confirmed by CT scan in National Medical Center from Jan. '79 to Aug. '82. The analysis is based on 10 cases with intracranial tuberculoma on whom operation was performed in 7 cases and conservative treatment was done in 3 cases. Extracranial disease or a past history of tuberculosis are evident in half of patients. The common presenting features are intracranial hypertension and papilledema. These are usually located in the supratentorial region. The use of CT brain scanning can be of great help in diagnosis and follow up more than others. The current treatment consists of medical therapy such as combined antituberculous agents, but surgical exploration may be reserved for intractable seizure, suspected brain tumor and medical failure or severe intracranial hypertension.
Brain
;
Brain Neoplasms
;
Diagnosis
;
Follow-Up Studies
;
Humans
;
Intracranial Hypertension
;
Papilledema
;
Seizures
;
Tomography, X-Ray Computed
;
Tuberculoma, Intracranial*
;
Tuberculosis
2.A case report of adenoid cystic carcinoma in trachea.
Hee Jae JUN ; Phil Cho CHOI ; See Young HAM ; See Chan SUNG ; Jong Soo WOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):501-504
No abstract available.
Adenoids*
;
Carcinoma, Adenoid Cystic*
;
Trachea*
3.Surgical treatment of Takayasu's arteritis: report of one case.
Hee Jae JUN ; phil Cho CHOI ; See Young HAM ; See Chan SUNG ; Jong Soo WOO
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(6):496-500
No abstract available.
Takayasu Arteritis*
4.Iatrogenic Aspiration of a Broken Metallic Stylet: A case report.
Jong Hwan LEE ; Chan Jong CHUNG ; Heon Soo PARK ; Phil Jo CHOI
Korean Journal of Anesthesiology 1998;34(1):182-186
Complications of tracheal intubation are well documented. However, iatrogenic aspiration of a broken metallic stylet following tracheal intubation has been infrequently reported. A 60-year-old woman, 10 days after shoulder arthroscopic surgery under endotracheal general anesthesia, was admitted to our hospital because of right chest pain. Chest radiographs showed a 8 cm length of metallic foreign body in the lower lobe of the right lung. Attempts at retrieval, including thoracoscopy, were unsuccessful. Open thoracostomy was performed. The removed foreign body was a part of metallic stylet. We report a case of iatrogenic aspiration of a broken metallic stylet.
Anesthesia, General
;
Arthroscopy
;
Chest Pain
;
Female
;
Foreign Bodies
;
Humans
;
Intubation
;
Lung
;
Middle Aged
;
Radiography, Thoracic
;
Shoulder
;
Thoracoscopy
;
Thoracostomy
5.A Case of Carotid Body Tumor: Case Report.
Hee Chul SHIN ; Soon Phil PARK ; Jong Hyun CHOI ; Jong Oung DOH
Journal of Korean Neurosurgical Society 1984;13(3):517-521
Carotid body tumor is uncommon and has been a source of fear and curiosity to the surgeon for many years. This puzzling tumor attaches itself so intimately to the carotid artery system that its routine removal is often associated with serious consequences. The justification for its extirpation has been debated vigorously. Recently, we have experienced a case of carotid body tumor and obtained good result after total removal. We report our case with a brief review of the articles.
Carotid Arteries
;
Carotid Body Tumor*
;
Carotid Body*
;
Exploratory Behavior
6.A Case of Intradural Vermian Schwannoma without Attachment to a Nerve Root.
Jae Kyu KANG ; Soon Phil PARK ; Jong Hyun CHOI ; Jong Oung DOH
Journal of Korean Neurosurgical Society 1984;13(3):505-509
A rare case of intradural cerebellar vermian schwannoma has been reported. A 43 years old woman admitted to our hospital because of headache and weakness of upper extremities. CT brain scan showed an irregular lower density with intermixed high density at the middle posterior fossa, and large lower density with peripheral irregular thickness of rim enhancement after contrast media. CT cervical spine showed a lower density with displaced cord to the right side on the dorsal surface at C1 portion. Total enucleation of irregular brownish-gray large cystic mass resulted in uneventful recovery. There was no attachment to any nerve root.
Adult
;
Brain
;
Contrast Media
;
Female
;
Headache
;
Humans
;
Neurilemmoma*
;
Spine
;
Upper Extremity
7.MRI Findings of Intracranial Hemangioblastoma.
Chang Soo KIM ; Seung Kug BALK ; Jong Deok KIM ; Chun Phil CHUNG ; Mee Young CHO ; Sun Sub CHOI
Journal of the Korean Radiological Society 1995;33(5):705-711
PURPOSE: Complete resection of the tumor nodule(mural nodule or solid portion of the tumor) is the essential goal of surgical treatment for heman-gioblastoma. The purpose of this study was to classify the morphologic types of intracranial hemangioblastoma on MRI and to compare the location and contour of tumor nodule on MRI with those on angiography. MATERIALS AND METHODS: The MRI findings of 34 lesions(38 lesions if 4 spinal cord lesions were included) in 26 patients(17 males and 9 females, range of age, 18-67 years, mean, 39 years) with surgically and histopathologically proved intracranial hemangioblastomas were reviewed. Seventeen patients underwent CT scanning in a short interval. Contrast-enahnced T1 -weighted imaging pa- tterns of hemangioblastoma were classified according to Ho's morphologic types. The location and contour of tumor nodule were compared between MRI and angiography in 15 patients(24 lesions). RESULTS: By location, cerebellar hemisphere was predominated(55%), followed by cerebellar vermis(26%), supratentorial region(5%), and medulla oblongata (3%). Spinal cord lesions(11%) were seen in 3 patients of 5 von HippeI-Lindau diseases. The frequency of morphologic types was as follows; Type 1 (purely cystic), 3%, Type 2(mural nodule), 50%, Type 3(cyst with wall enhancement), 3%, Type 4 (cystic nodule), 15%, Type 5(solid with internal cyst), 9%, and Type 6(solid), 20%. All tumor nodules(33 lesions) enhanced intensely with intravenous contrast material on MRI, of which 24 lesions(in 15 patients) revealed hypervascular masses fed by pial arteries on angiography. They were superficial and abutted pia mater partially or in large portion on both MR I and angiography. CONCLUSION: Over 70% of intracranial hemangioblastomas had a surrounding cyst, and superficial, pial-based location and number of the tumor nodules on MRI was correlated well with those on angiography. MRI is the examination of choice for preoperative evaluation of intracranial hemangioblastoma.
Angiography
;
Arteries
;
Female
;
Hemangioblastoma*
;
Humans
;
Magnetic Resonance Imaging*
;
Male
;
Medulla Oblongata
;
Pia Mater
;
Spinal Cord
;
Tomography, X-Ray Computed
8.In vitro Effect of Sophora flavescens on the Ultrastructure of Trichomonas vaginalis Donne.
Won Gyu CHOI ; Yoo Joung CHO ; Jong Phil CHU
Korean Journal of Infectious Diseases 2002;34(4):248-254
BACKGROUND: Trichomonas vaginalis is a pathogenic protozoa infecting human genitourinary tract. Metronidazole is currently the drug of choice to treat T. vaginalis infection. However, because of the side effects and the occurrence of resistant strains of metronidazole, it is needed to investigate alternatives. METHODS: The antiprotozoal effect of aquatic extract from Sophora flavescens on the growth and fine structure of T. vaginalis was examined by using trypan blue exclusion assay and electron microscopy. RESULTS: One hour after the addition of 4 mg/mL extract and half hour after the addition of 5 mg/mL showed antiprotozoal effect. One to two hours after the addition of 3 mg/mL extract, the movement of flagella and axostyle had disappeared, but death of the cells had not occurred until two hours after the addition. The fine structure of the cytoplasm was also changed half an hour to two hours after addition. The number of polyribosome decreased when that of single ribosomes in the cytoplasm increased. CONCLUSION: These results indicated that S. flavescens had the antiprotozoal effect on T. vaginalis by inhibition of cell multiplication as well as an impairment of protein synthesis.
Cell Proliferation
;
Cytoplasm
;
Flagella
;
Humans
;
Metronidazole
;
Microscopy, Electron
;
Polyribosomes
;
Ribosomes
;
Sophora*
;
Trichomonas vaginalis*
;
Trichomonas*
;
Trypan Blue
9.Distribution of the Dopamine D1 and D2 Receptor Protein Using Immunohistochemistry in Wistar-Kyoto Rat (WKY) and Spontaneously Hypertensive Rat (SHR) Kidneys.
Se Ho CHANG ; Jong Duk LEE ; Gyeong Jae CHO ; Phil Ok KOH ; Wan Sung CHOI ; Sun Il CHUNG
Korean Journal of Nephrology 1998;17(6):841-852
The kidney and balances of fluid and volume are the basic components of bloocl pressure control, and the kidney is the primary site that initiates the hypertensive process and is affected by hypertensive vascular disease. In the kidney, the dopamine is a potent natriuretic and vasodilating agent, participat- ing in renal sodium excretion and maintenance of cardiovascular homeostasis. And the dopamine receptors in central nervous system and peripheral organs were identified by physiological, biochernical and radioligand binding techniques. Rut previous morphological and biochemical studies have been unable to characterize or determine the tissue distribution of the dopamine receptor subtypes because no selective ligands are available yet. Furthermore, the cellular distribution of the dopamine receptor subtypes in the rat kidney is not demonstrated well. In the SHR, the ability of exogenous and endogenous renal dopamine to engender a natriuresis is impaired. Since renal dopamine levels in genetic models of hypertension are not lower than their normotensive controls, the impaired intrarenal paracrine effect of dopamine in these animal models of hypertension appears to be receptor or postreceptor mediated. And renal dopamine derives mainly from renal tubular dopamine production and to a lesser extent from dopaminergic nerves. The present study utilizes imrnunohistochemistry with specific antibodies to characterize the renal distribution of dopamine receptor subtypes and recognize the role of dopamine receptor defect in the pathogenesis of hypertension in 14-week-old WKY (mean HP 108+/-5mmHg) and SHR (mean RP 174+/-7 mmHg) kidneys. Also it utilizes antibody of tyrosine hyclroxylase (TH) to recognize the site of the dopamine production mediated by TH using light microscopic immunohistochemistry. In the immunohistochemistry of the WKY kidney, dopamine D1 receptor protein is localized to glomerulus, proximal tubule, distal tubule, renal vessels, cortical and medullary collecting duct. And in the SHR kidney, dopamine D1 receptor protein is localized to glomerulus, distal tubule, renal vessels, cortical and medullary collecting duct, and juxtaglomerular apparatus (JGA). But there is no demonstrable positive reaction in the proximal tubule and weakly positive reactions in the renal arterioles of SHR compared with WKY kidney. In the immunohisto-chemistry of the WKY kidney, dopamine D1 receptor protein is localized to glomerulus, proxirnal tubule, distal tubule, renal vessels, cortical and rnedullary collecting duct. And in the SHR kidney, dopamine D2 receptor protein is localized to glomerulus, distal tubule, renal vessels, cortical and medullary collecting duct, and JGA. So, there is no demonstrable positive reaction in the proximal tubule of SHR compared with WKY. In the glomerulus of the WKY and SHR kidneys, both dopamine D1 and D2 receptors are localized. In the in situ hybridization of the WKY and SHR kidneys, dopamine D and D receptors are only demonstrated at the renal vessels. The positive reaction to TH immunohistochemistry of the WKY and SHR kidneys is only observed in the renal medulla compared with negative reaction on the renal cortex. Considering the excretion of sodium up to 65-70% with volume expansion may be mediated by dopamine D1-like receptors in the proximal tubule, our immunohistochemistry findings for the dopamine receptors may support the failure of natriuretic response in the SHR due to an abnormal dopamine receptor. Also our results rnay mean that the glornerular filtration rate is mediated by both dopamine D1 and Dz receptors comparing with the previous studies that the glomerular filtration rate was mediated by dopamine D2 receptor. I'here are some differences in the receptors expressing sites on the previous radioligand binding and pharmacologic studies, but our results suggest that at least some of the renal dopamine DA and DAz receptors correspond structurally to the central dopamine D1 and D2 receptors. Finally the result of TH immunohisto-chemistry suggests that the production of dopamine in the proximal tubule is not mediated by TH.
Animals
;
Antibodies
;
Arterioles
;
Central Nervous System
;
Dopamine*
;
Filtration
;
Glomerular Filtration Rate
;
Homeostasis
;
Hypertension
;
Immunohistochemistry*
;
In Situ Hybridization
;
Juxtaglomerular Apparatus
;
Kidney*
;
Ligands
;
Models, Animal
;
Models, Genetic
;
Natriuresis
;
Rats*
;
Rats, Inbred SHR*
;
Receptors, Dopamine
;
Receptors, Dopamine D1
;
Receptors, Dopamine D2
;
Sodium
;
Tissue Distribution
;
Tyrosine
;
Vascular Diseases
10.Using dental virtual patients with dynamic occlusion in esthetic restoration of anterior teeth: case reports
Phil-Joon KOO ; Yu-Sung CHOI ; Jong-Hyuk JONG-HYUK ; Seung-Ryong HA
The Journal of Korean Academy of Prosthodontics 2023;61(4):328-343
Recently, a method of fabricating an esthetic anterior fixed prosthesis by integrating data such as three-dimensional facial scan and jaw motion to form a virtual patient with dynamic occlusion has been introduced. This enables smooth communication with patients during the diagnosis process, improves the predictability of esthetic prosthetic treatment, and lowers the possibility of occlusal adjustment. In this case report, a virtual patient with dynamic occlusion was created in which the results of the treatment were simulated, and esthetic maxillary anterior fixed prosthesis was fabricated. With the aid of the virtual patient, the final restorations were satisfactory both in terms of esthetic and function.