No abstract available.
Abstracting and Indexing as Topic* ; Evidence-Based Medicine* ; Methods*

BACKGROUND: As modern epidemiologic studies began to identify obesity as a risk factor for cardiovascular disease, diabetes, hypertension, and cancer, measuring the degree of excess body fat is important on epidemiologic surveys. The evaluation of obesity level in epidemiologic surveys has been mostly done indirectly by measuring patient's height and weight. But, the anthropometry could not be done to respondents of recalling past anthropometric values or to proxy respondents. This study was attempted to elucidate usefulness of a somatotype drawing as a measuring instrument of obesity level in epidemiologic surveys in Korea. METHOD: The inclusion criteria of subjects were (1) members of the Seoul Cohort Study, who were recruited by self-administered structured questionnaire survey through mailing to the healthy men between the ages of 40 and 59 years through the program of a biennial health checkup offered by the Korean Medical Insurance Corporation (KMIC), and (2) volunteers for cancer screening program offered by KMIC. For assessing usefulness of the instrument, measurement of status/weight and self-administered questionnaire survey were done separately through the program of a biennial health checkup and of cancer screening. RESULTS: The data were collected from 138 subjects, whose Body Mass Index (kg/M2) was 23.58+/-1.46 (mean+/-SD). When the validity was measured through correlation with BMI, Spearman's correlation coefficient (rs) was 0.72 (p<0.05), that remained statistically significant after adjusting age, education level, and monthly income and occupation. And, the grades of somatotypo drawing were grouped as 1-3, 4-6, 7-8 by ANOVA and Tukey test. CONCLUSIONS: Instrument using somatotype drawing is applicable to screen degree of body fat in self-administered questionnaire surveys in Korea.
Adipose Tissue ; Anthropometry ; Body Mass Index ; Cardiovascular Diseases ; Cohort Studies ; Surveys and Questionnaires ; Early Detection of Cancer ; Education ; Epidemiologic Studies ; Humans ; Hypertension ; Insurance ; Korea* ; Male ; Obesity* ; Occupations ; Postal Service ; Proxy ; Risk Factors ; Seoul ; Somatotypes* ; Volunteers

The aim of this study was to assess the degree of association between individual stress and the amount of smoking among male senior students of a medical college. The questionnaire survey was conducted twice for collecting the data on stress level in terms of BEPSl score, smoking amounts, alcohol intake, and residence type in 1992 and 1993. Among the 223 responders, 39.9% were smokers. In the smokers, the association between stress level and smoking amount was significant after controlling for alcohol intake and residence type (P < 0.l). Especially in the group of living without family, the association was more significant (p=0.06). Therefore, it is recommendable that the stress management program is called upon for the student smokers to reduce smoking amount.
Humans ; Male ; Surveys and Questionnaires ; Smoke* ; Smoking*

After publishing results of a study that revealed diarrheagenic and emetic activity in 4-5-day old mice infected with Kudoa septempunctata (K. septempunctata) spores, the Korea Centers for Disease Control and Prevention reported 11 events of “Kudoa food poisoning” in 2015. The epidemiological design of the previous study was descriptive rather than analytical; therefore, this study aimed to further investigate the pathogenicity of K. septempunctata. Academic articles showing evidence of the pathogenicity of K. septempunctata were searched via PubMed using the citation discovery tool. Information regarding the kinds of experimental animals and inoculum spores used, as well as study results were extracted. Four articles evaluating the pathogenicity of Myxospran parasites were selected; the first article suggested the pathogenicity of K. septempunctata, while the remaining three articles reported no abnormal symptoms or histopathologic changes. Our findings indicate that there is weak evidence supporting the pathogenicity of K. septempunctata. Further studies evaluating the pathogenicity of K. septempunctata are needed urgently.
Animals ; Centers for Disease Control and Prevention (U.S.) ; Food Parasitology ; Foodborne Diseases* ; Intestinal Diseases, Parasitic ; Korea ; Mice ; Myxozoa ; Parasites ; Spores ; Virulence

After publishing results of a study that revealed diarrheagenic and emetic activity in 4-5-day old mice infected with Kudoa septempunctata (K. septempunctata) spores, the Korea Centers for Disease Control and Prevention reported 11 events of “Kudoa food poisoning” in 2015. The epidemiological design of the previous study was descriptive rather than analytical; therefore, this study aimed to further investigate the pathogenicity of K. septempunctata. Academic articles showing evidence of the pathogenicity of K. septempunctata were searched via PubMed using the citation discovery tool. Information regarding the kinds of experimental animals and inoculum spores used, as well as study results were extracted. Four articles evaluating the pathogenicity of Myxospran parasites were selected; the first article suggested the pathogenicity of K. septempunctata, while the remaining three articles reported no abnormal symptoms or histopathologic changes. Our findings indicate that there is weak evidence supporting the pathogenicity of K. septempunctata. Further studies evaluating the pathogenicity of K. septempunctata are needed urgently.
Animals ; Centers for Disease Control and Prevention (U.S.) ; Food Parasitology ; Foodborne Diseases ; Intestinal Diseases, Parasitic ; Korea ; Mice ; Myxozoa ; Parasites ; Spores ; Virulence

No abstract available.
Adult ; Carcinogens/toxicity ; Environmental Exposure ; Genome, Human/radiation effects ; Humans ; Neoplasms, Radiation-Induced/epidemiology/etiology/*genetics ; *Nuclear Power Plants ; Republic of Korea/epidemiology ; Thyroid Neoplasms/epidemiology/etiology/*genetics

No abstract available.
Humans ; *Public Health

OBJECTIVES: Using the population-based cancer registry in Jejudo, we found that Jejudo had lower incidence in stomach cancer than other regions in Korea. The aim of this study was to evaluate reasons for this difference. METHODS: Citrus is the leading agricultural production in Jejudo, suggesting that lower cancer incidence in Jejudo could be explained by citrus fruit intake. We evaluated this hypothesis with quantitative systematic review (QSR). RESULTS: Stomach cancer incidence was significantly lower, with a summary odds ratio (SOR) after QSR of 0.72 [95% CI=0.64-0.81]. In addition, the SOR of pancreatic cancer tended to be lower at 0.83 [95% CI=0.70-0.98]. The SOR of prostate cancer was slightly higher at 1.03 [0.89-1.19]. CONCLUSIONS: Quantitative systematic reviews for the effect of citrus fruit intake on cancer occurrence suggested that lower cancer incidence in Jejudo could be explained by intake of citrus fruits.
*Citrus ; Female ; Humans ; Incidence ; Korea/epidemiology ; Male ; Neoplasms/*epidemiology ; Odds Ratio ; Pancreatic Neoplasms/epidemiology ; Prostatic Neoplasms/epidemiology ; *Registries ; Stomach Neoplasms/epidemiology

OBJECTIVES: 'High-normal blood pressure' is a factor influencing decision to initiate targeted intensive intervention strategy in westernized populations. JNC-VI offered the vigorous lifestyle modification for persons with 'high-normal blood pressure', who could be early detected. As a hypertension seems to be the result of multiple genetic factors operating in concert with associated environmental factors, it will be necessary to identify the high-normal blood pressure as a risk factor of hypertension for applying primary prevention strategy in Korean people. METHODS: Although cohort study design might be adequate to recruit incidence cases, to keep time sequence of events, and to prevent information bias, nested case-control study was chosen for avoiding measurement errors because hypertension is a benign disease. Source population was the 'Seoul Cohort' participants and follow-up was done by using Korea Medical Insurance Corporation's database on the utilization of health services from 1Jan93 to 30Jun97. Incidence cases were ascertained through the chart review, telephone contacts, and direct blood pressure measurements. Controls included the pairing of 4 individuals to each case on the basis of age. RESULTS: As 75 % of 247 incident cases had high-normal blood pressure, the crude odds ratio for hypertension was 2.04 (95% CI 1.47-2.83). Another statistically significant risk factors of hypertension were body mass index, dietary fiber, alcohol consumption, weekly activity and history of quitting smoking. The multivariate odds ratio of high-normal blood pressure adjusted for all risk factors was 1.84 (95 % CI 1.31-2.56). Among high-normal blood pressure group, body mass index, weekly ethanol amounts, weekly physical activity, and dietary fiber except history of quitting smoking were still risk factors of hypertension. CONCLUSION: 'High-normal blood pressure' is a risk factor for hypertension in Korean middle-aged men, which represents that the vigorous lifestyle modification for persons with 'high-normal blood pressure' is need.
Alcohol Drinking ; Bias (Epidemiology) ; Blood Pressure* ; Body Mass Index ; Case-Control Studies* ; Cohort Studies ; Dietary Fiber ; Ethanol ; Follow-Up Studies ; Health Services ; Humans ; Hypertension* ; Incidence ; Insurance ; Korea ; Life Style ; Male ; Motor Activity ; Odds Ratio ; Primary Prevention ; Risk Factors* ; Smoke ; Smoking ; Telephone

A main aim of the Evidence-based Medicine is to make the best decision by related evidence in supplying healthcare services. To apply evidence-practice gap (EPG) is very helpful to scan for what evidence is necessary. EPG gave 4 parts depending on the existence of evidence and practice. Comparative effectiveness research could be suggested in the part on conducting a practice with evidence. Translational research would be applied in the part on no practice without evidence. The adaptation of previously clinical practice guideline (CPG) should be conducted in the part on treating patients without evidence. Finally, de novo development of CPG would be undertaken in the situation of not applying the known evidence for clinical practice. These trials would bring us to a new level in improving the level of quality in the nationwide healthcare system as well as to progress achievements in the Korean medical academy.
Comparative Effectiveness Research ; Delivery of Health Care ; Evidence-Based Medicine ; Evidence-Based Practice ; Humans ; Practice Guidelines as Topic ; Translational Medical Research