We report a case of 41-year-old male with pulmonary metastasis from a recurrent intracranial malignant meningioma, which had two more recurrence, multiple intracranial metastasis. Pulmonary metastasis was developed five years after resection of primary lesion. The metastatic routes and treatment of pulmonary metastatic malignant meningiomas were described.
Adult ; Humans ; Male ; Meningioma* ; Neoplasm Metastasis* ; Recurrence

Although technological advances and clinical studies on stem cells have been increasingly reported in stroke, research targeting hemorrhagic stroke is still lacking compared to that targeting ischemic stroke. Studies on hemorrhagic stroke are also being conducted, mainly in the USA and China. However, little research has been conducted in Korea. In reality, stem cell research or treatment is unfamiliar to many domestic neurosurgeons. Nevertheless, given the increased interest in regenerative medicine and the increase of life expectancy, attention should be paid to this topic. In this paper, we summarized pre-clinical rodent studies and clinical trials using stem cells for hemorrhagic stroke. In addition, we discussed results of domestic investigations and future perspectives on stem cell research for a better understanding.

Topographic electroencephalographic study(CME) is a newly developed method using a microcomputer system that displays the scalp topograph as the square roots of the average power spectra over each EEG frequency band on a color television screen. CME were applied to thirty patients, Fifteen patients out of them with focal neurologic deficit were analysed about CT scan and conventional EEG. The results of the study were as follows : 1) Comparing the results of CME and conventional EEG reading, CME revealed to be slightly more sensitive in detecting asymmetrical depression of background activity than the conventional reading of the EEG. 2) Topograph EEG study was more accurate than conventional EEG in lateralization of the lesion. 3) CME is very useful in topographic and objective diagnosis of functional lesion, although the source of the data is the same as that from the conventional EEG.
Depression ; Diagnosis ; Electroencephalography ; Humans ; Microcomputers ; Neurologic Manifestations ; Scalp ; Television ; Tomography, X-Ray Computed

Experimental subarachnoid hemorrhage(SAH) was produced in adult cats by injection of autologous blood(6ml) into prepontine cistern by tranclival approach and cisterna magna. The animals were sacrificed 1, 3, 5, 7 or 14 days later and basilar artery segments were prepared for electron microscopy. The following observations were made: 1) 1 to 7 days after SAH, electron micrograph showed round-shaped endothelial cells in tunica intima and disappearance of zonular occludens. Endothelial detachment from internal elastic membrane and intracytoplasmic vacuolation of endothelial cells as well as destruction of mitochondrial cirstae in tunica media. 2) 14 days after SAH, electron micrograph showed the normal findings in tunica intima and tunica media of the vessel walls. On the basis of the above findings, I found that the ultrastructural changes in the basilar arterial wall, which had presumably developed as a consequence of experimental SAH were reversible.
Adult ; Animals ; Basilar Artery* ; Cats ; Cisterna Magna ; Endothelial Cells ; Humans ; Membranes ; Microscopy, Electron ; Subarachnoid Hemorrhage* ; Tunica Intima ; Tunica Media

Experimental subarachnoid hemorrhage(SAH) was produced in adult cats by injection of autologous blood(6ml) into prepontine cistern by tranclival approach and cisterna magna. The animals were sacrificed 1, 3, 5, 7 or 14 days later and basilar artery segments were prepared for electron microscopy. The following observations were made: 1) 1 to 7 days after SAH, electron micrograph showed round-shaped endothelial cells in tunica intima and disappearance of zonular occludens. Endothelial detachment from internal elastic membrane and intracytoplasmic vacuolation of endothelial cells as well as destruction of mitochondrial cirstae in tunica media. 2) 14 days after SAH, electron micrograph showed the normal findings in tunica intima and tunica media of the vessel walls. On the basis of the above findings, I found that the ultrastructural changes in the basilar arterial wall, which had presumably developed as a consequence of experimental SAH were reversible.
Adult ; Animals ; Basilar Artery* ; Cats ; Cisterna Magna ; Endothelial Cells ; Humans ; Membranes ; Microscopy, Electron ; Subarachnoid Hemorrhage* ; Tunica Intima ; Tunica Media

Craniopharyngiomas are usually considered to arise from the pituitary stalk and upper aspect of the pituitary gland. However, they very rarely develop from the floor of the third ventricle or the lamina terminalis, and are intrinsically confined to the third ventricle ; about 40 cases have been reported in the literatures. We have recently experienced a case of intrinsic intraventricular craniopharyngioma with the density a little higher than cerebrospinal fluid on the brain CT.
Brain ; Cerebrospinal Fluid ; Craniopharyngioma* ; Hypothalamus ; Pituitary Gland ; Third Ventricle

This is a report on the sudden onset of the Brown-Se`quard Syndrome on a patient following extradural cervical disc herniation. Earlier diagnosis and prompt surgical decompression in the lateral cord syndrome yielded a good outcome.
Decompression, Surgical ; Humans ; Spinal Cord Diseases

Defects in the dura mater can be result from craniocerebral trauma, neoplastic or inflammatory destruction surgical removal and congenital absence. Materials used for closure of dural defects were variable. Of these, autogenous fascia lata have been used for a long time. It seems interesting to study the histologic fate of the autogenous grafted fascia lata in the dural defects. After autogenous fascia lata graft to dural defect in 18 rabbits, the histologic fate of the autogenous grafted fascia lata was observed microscopically. The results are as follows: 1) The adhesions among the grafted fascia lata, arachnoid, pia mater and brain cortex were usually mild. This result may be due to either short period of observation or autogenous substitutional material. 2) The grafted autogenous fascia lata was revealed minimal inflammatory response and was ultimately reabsorbed. 3) The grafted autogenous fascia lata was replaced by granulation tissue and fibroblast originated from the host mesenchymal tissue.
Arachnoid ; Brain ; Craniocerebral Trauma ; Dura Mater ; Fascia Lata* ; Fascia* ; Fibroblasts ; Granulation Tissue ; Pia Mater ; Rabbits* ; Transplants

OBJECTIVE: Stroke is the third leading cause of death in the Republic of Korea. Time is the most important factor in hyperacute stroke. Yet, there had been no protocol for mechanical thrombolysis. We have treated patients with hyperacute stroke by mechanical thrombolysis for 3 years. In current study, we analyzed the outcome of mechanical thrombolysis. METHODS: From March 2008 to February 2011, 36 patients were treated with mechanical thrombolysis. Initially we treated the patients by aggressive mechanical clot disruption (AMCD) who were admitted within 6 hours after the symptom onset. If revascularization was not achieved, balloon angioplasty was performed, followed by stenting or temporary endovascular bypass was performed. The result in 15 cases was not so successful. Since then, we started using the thromboaspiration method as the first line treatment of the mechanical thrombolysis. RESULTS: After using the thromboaspiration, we had better results in recanalization rate, modified Rankin Score (mRS) and reperfusion injury compared to AMCD. The recanalization rate was 80.85%, mRS is 2.85, and there was only 0.09% hemorrhagic formation. CONCLUSION: Even though thromboaspiration is not statistically significant due to the limited numbers of patients enrolled in this study, we think it is a good way in mechanical thronbolysis for hyperacute stroke.
Angioplasty, Balloon ; Cause of Death ; Humans ; Mechanical Thrombolysis ; Reperfusion Injury ; Republic of Korea ; Stents ; Stroke

Intracranial arachnoid cysts are uncommon congenital lesions of considerable interest and importance, the origins and exact nature of which remain uncertain. They account for about 1% of all intracranial space-occupying lesions4). Its predilection sites are in the sylvian fissure, the interhemispheral fissure, the cerebral convexity, the base of the brain, and over the midline of the cerebellum in the posterior fossa6)11). We are reporting a case of arachnoid cyst, developed in the left sylvian fissure in a ten years old male patient.
Arachnoid ; Arachnoid Cysts* ; Brain ; Cerebellum ; Humans ; Male