1.Adverse factors of hepatic dysfunction during chemotherapy for childhood malignancy.
Dong Hoon KOH ; Hyung Jong LIM ; Young Kwon CHOI ; Hoon KOOK ; Tae Joo HWANG
Journal of the Korean Cancer Association 1993;25(3):417-422
No abstract available.
Drug Therapy*
2.Clinical analysis of diagnostic method in obscure origin of gastrointestinal bleeding.
Jong Soo LEE ; Suk Won LIM ; Kyung Sup SONG ; Eung Kook KIM ; Sang Yong CHOO
Journal of the Korean Surgical Society 1992;42(2):267-274
No abstract available.
Hemorrhage*
3.Clinical analysis of diagnostic method in obscure origin of gastrointestinal bleeding.
Jong Soo LEE ; Suk Won LIM ; Kyung Sup SONG ; Eung Kook KIM ; Sang Yong CHOO
Journal of the Korean Surgical Society 1992;42(2):267-274
No abstract available.
Hemorrhage*
4.Effects of Panax ginseng Aqua - acupuncture on Lymphocyte Activities in Glucocorticoid Treated Mice.
Kyung Soo NAM ; Jin Young MOON ; Mi Jung CHOI ; Eun Hong LEE ; Doo Hie KIM ; Jong Kook LIM
Korean Journal of Immunology 1997;19(3):355-362
Panax ginseng (PG) has been used as an important analeptic in traditional medicine. This study was purposed to investigate the effect of PG on immune responses induced by glucocorticoid in mice. PG solution was injected into CV6 and BL23, which are the classical acupuncture points, for 7 days after injection with glucocorticoid. And then B and T cell proliferation and cytolytic activity of natural killer (NK) cells were measured. B cell proliferation by 'H-thymidine incorporation was decreased by about 25% in control group as compared with normal group. However, B cell proliferation was significantly increased 1.8-fold in CV6 group and 2.5-fold in BL23 group as compared with normal group. T cell proliferation by H- thymidine incorporation was decreased by about 15% in control group as compared with normal group. On the other hand, T cell proliferation was significantly increased 1.9-fold in CV6 group and 2.3-fold in BL23 group as cornpared with normal group. Furthermore in purified T cell, the proliferation was furtherly increased rather than in non-purified T cell. The activity of NK cell was remarkably decreased in control group as compared with normal group. However, the activities of NK cells in CV6 and BL23 groups were recovered to the above levels of normal group. On the other hand, the activity of NK cell in the blank locus group was slightly increased compared with control group. However this increasement was not reached the levels of CV6 and BL23 groups. And in the case of purified NK cell, the cytolytic activity of NK cell was respectively increased 1.6-fold in normal group, 1.4-fold in control group, 2.0-fold in blank locus group and 2.0-fold in CV6 group and 1.4-fold in BL23 group as compared to the non-purifed NK cell. These results suggest that PG aqua-acupuncture at CV6 and BL23 may proliferate B and T cells that is suppressed by glucocorticoid, and activate NK cell activity.
Acupuncture Points
;
Acupuncture*
;
Animals
;
Cell Proliferation
;
Hand
;
Killer Cells, Natural
;
Lymphocytes*
;
Medicine, Traditional
;
Mice*
;
Panax*
;
T-Lymphocytes
;
Thymidine
5."Histologic Examination of Histoacryl When Used in a Subcutaneous Sites.": An Experimental Study.
Dong Moung SHIN ; Jong Yoo KIM ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 1999;29(4):913-927
No abstract available.
Enbucrilate*
6.The Effects of the Argon Laser Irradiation on the Root Surface: A Scanning Electronic Microscopic Study.
Hee Jong EUN ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 1999;29(4):861-871
Since pathologic changes of exposed root surface inhibit cell attachment and new attachment of connective tissue have been made, many efforts were apply to change the exposed root surface condition. Scaling and root planing can not remove the endotoxin completely and forms the smear layer which prohibits the new attachment of connective tissue. Therefore, many kinds of chemicals were used for controlling the pathologic change of the root surface. The purposes of this study was to compare and observe the changes of the exposed root surface treated by scaling and root planning, Tetracycline HCl and Argon Laser. After the scaling and root planning of ten extracted premolars, the differences & the root surface among groups were observed under SEM. Control group showed smear layer and irregular amorphous surface. The dentinal tubule was not exposed. The debris and scale like texture were also observed. Tetracycline HCl treated group showed relatively smooth surface and the collagen fiber was observed in the dentinal tubule. Argon Laser treated group showed the most effective results under the conditions of 0.8 to 1.0w irradiation for 0.5 to 1.0 sec with pulse wave. The results of this study showed that the root surface change was associated with the intensity and the duration of Argon Laser irradiation. Further investigation for the surface change with the Argon Laser irradiation is recommended for understanding of clinical effect.
7.Periodontally Diseased Root and Normal Root as Studied by Electron Probe Microanalysis & SEM.
Jong Sig KIM ; Chong Yeo KIM ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 1999;29(2):401-413
Root surfaces affected by periodontal disease undergo various forms of changes. Cementum exposure from gingival recession may result in absorption of calcium, phosphorus, and fluoride and subsequent hypermineralization and increased radiodensity. Although some reports have suggested that inorganic content with root cementum might show various changes depending upon age or extent of periodontal disease, but no consensus can be reached regarding the the distribution of various elements. The present study examines the difference in mineral content between healthy and periodontal diseased roots by analyzing three areas per tooth along the root surface in cervico-apical direction using electron probe and scanning electron microscope. Healthy tooth that was extracted for orthodontic purpose was used as control. Experimental teeth include those with periodontal pocket depth exceeding 6mm and those with gingival recession and periodontal pocket depth of 2-4mm. Levels of Ca, P, Mg and Na were measured using wavelength dispersive x-ray spectrometer at three areas per tooth. The examined areas were located apical to cemento-enamel junction in control and periodontal ligament-depleted areas in experimental teeth. The corresponding areas were also examined with scanning electron microscope(x70) The results are as follows. 1. Minerals were detected in order of Ca, P, Mg and Na. In all root surfaces, levels of Ca and P were higher in dentin than in cementum. 2. Level of Mg was twice as high in dentin than in cementum. There was no significant difference in the level of Mg and Na between normal and periodontal diseased roots or between the various locations in the same root. 3. Level of Ca and P in the surface cementum showed no difference between normal and periodontal diseased root, although the areas in dentin with high level of either ion also showed high level of corresponding ion incementum. 4. Difference in the Ca and P content between various locations within the same root was noted, although no coherent pattern existed. These results suggest that although the mineral content of the root cementum in periodontitis-affected tooth is affected by exogenous ions from saliva and food, but there was no difference in the mineral contents between normal and periodontally diseased root.
Absorption
;
Calcium
;
Consensus
;
Dental Cementum
;
Dentin
;
Electron Probe Microanalysis*
;
Fluorides
;
Gingival Recession
;
Ions
;
Minerals
;
Periodontal Diseases
;
Periodontal Pocket
;
Phosphorus
;
Saliva
;
Tooth
8.The Biological Effects of Calcium Phosphate Coated Implant for Osseointegration in Beagle Dogs.
Eon Cheol SHIM ; Sung Bin LIM ; Chin Hyung CHUNG ; Jong Yeo KIM
The Journal of the Korean Academy of Periodontology 2003;33(4):651-671
The influence of calcium phosphate (Ca-P) coating on the bone response of titanium implants was investigated two types of titanium implants, i.e. as -machined ,as -machined with Ca-P coating, were prepared. The Ca-P coating produced by OCT Inc technique. These implants were inserted into the left and right femur of beagle dog. After implantation periods of 3 days, 1weeks, weeks, 4weeks, 8weeks, 12weeks, 24weeks, the bone-implant interface was evaluated histologically, histomorphometrically, and removal torque. Histological evaluation revealed no new bone formation around different implant materials after 2weeks of implantation. After 4 weeks, Ca-P coated implants showed a higher amount of bone contact than either of the non coated implants. After 12weeks, bone healing was almost completed. And implant were removed by reverse torque rotation with torque-measuring device. Mean torque values for 4weeks control were 2.375Kgf.cm and experimental were 2.725Kgf.cm. And mean torque values for 8weeks control were 1.25Kgf.cm and experimental were 1.0Kgf.cm On the basis of these findings, we concluded that deposition of a Ca-P coating on an implant has a beneficial effect on the bone response to this implant during the healing phase. Besides implant surface conditions the bone response is also determined by local implant site condition.
Animals
;
Calcium*
;
Dogs*
;
Femur
;
Osseointegration*
;
Osteogenesis
;
Titanium
;
Torque
9.A Case of Percutaneous Intracavitary Amphotericin B Injection for the Treatment of Hemoptysis due to Pulmonary Aspergilloma.
Woa Ja LIM ; Kook Kyu KIM ; Myung Jun KIM ; Jong Gil WOO ; Hong Suk KIM ; Byung Ho KIM
Tuberculosis and Respiratory Diseases 1994;41(1):42-46
Pulmonary Aspergillomas usually arise from proliferation of Aspergillus in preexisting parenchymal cavities.202 college students (99 men, 103 women) aged 18% 26 years. Fasting blood samples were. The most common symptom in this disorder is hemoptysis, which may be minimal in amount or it may be massive & life threatening. The optimum therapy for pulmonary aspergilloma is controversial. The major options available include surgical resection of the lesion, a number of medical therapies, or simple observation of the patient for a time. Surgery is the most effective treatment but it is limited to some patient because most patients haute underlying pulmonary disease. Thus the various form of medical therapy was available with successful result. The authors present a case of percutaneous intracavitary amphoterician B injection for the treatment of pulmonary aspergilloma & its successful effect for the repetitive hemoptysis.
Amphotericin B*
;
Aspergillus
;
Fasting
;
Hemoptysis*
;
Humans
;
Lung Diseases
;
Male
10.Relation Between Pulmonary Hypertension and Mitral Stenosis Severity in Patients Undergoing Balloon Mitral Commissurotomy.
Byung Jin KIM ; Yong Hyun PARK ; Yoong In PARK ; Jong Hoon LIM ; Hyun Myung OAH ; Joon Hoon JEONG ; Kook Jin CHUN ; Taek Jong HONG ; Yung Woo SHIN
Korean Circulation Journal 1997;27(5):523-531
BACKGROUND: In patients with mitral stenosis, the degree of pulmonary hypertension is expected to be related to the severity of mitral valve obstruction. However, some patients with severe mitral stenosis do not develop reactive pulmonary hypertension. MATERIALS AND METHODS: We evaluated 34 patients with symptomatic mitral stenosis undergoing percutaneous mitral valvuloplasty by clinical, echocardiographic, and invasive hemodynamic(cardiac cathrterization) data. Prevalvuloplasty data were available in 34 subjects[mean age 38+/-9 year ; women 74% ; NYHA class 1 (6 patients), class 2 (17 patients), class 3 (7 patients), class 4 (4 patients) ; in electrocardiography, NSR(23 patients), Atrial fibrillation(11 patients)]. RESULTS: 1) The pulmonary vascular bed gradient was significantly correlated with pulmonary vascular resistance(r=0.91), mean pulmonary artery pressure(r=0.82), transmitral mean pressure gradient(r=0.64) and mitral valve area(r=-0.48). The pulmonary vascular resistance was significantly correlated with mena pulmonary artery pressure(r=0.77), transmiral mean pressure gradient(r=0.61) and mitral valve area(r=-0.54), NYHA functional classification(r=0.36). However, the pulmonary vascular bed gradient and pulmonary vascular resistance was not significantly correlated with age, sex, cardiac output, the severity of mitral regurgitation and mean left atrial pressure. 2) The mean pulmonary artery pressure was significantly correlated with mean left atrial pressure(r=0.80), transmitral mean pressure gradient(r=0.72) and mitral valve area(r=-0.47). 3) When patients were divided into those with a pulmonary vascular bed gradient > 12mmHg and = 12mmHg, the two groups were significantly different for many of these measures-Pulmonary vascular resistance(p=0.004), mean pulmonary artery pressure(p=/p<0.0001), transmitral mean pressure gradient(p=0.008), mitral valve area(p=0.04). 4) The mean left atrial pressure was significantly correlated with mean pulmonary artery pressure but not with pulmonary vascular resistance and pulmonary vascular bed gradient as the index of reactive pulmonary hypertension. 5) Results of multiple regressin analysis of factors affecting pulmonary vascular bed gradient showed that transmitral mean pressure gradient was the most significant factor(op<0.0001). 6) The decrease in mean pulmonary artery pressure from immediate before to immediate after balloon commissurotomy was related to pulmonary vascular resistance(r=0.51), pulmonary vascular bed gradient(r=0.63), mean left atrial pressure(r=0.60), transmitral mean pressure gradient(r=0.50), mitral valve area(r--0.41). CONCLUSION: In patients with mitral stensis, the degree of reactive pulmonary hypertension was significantly related to the severity of mitral stenosis(transmitral mean pressure gradient, mitral valve area) but not to mean left artial pressure. In some patients the degree of mitral stenosis could not expect the development of reactive pulmonary hypertension. It is suggested that specific predictors of pulmonary hypertension on an individual patient cannot be identified based solely on the severity of mitral valve disease and must include many factors associated with pulmonary parenchymal diseases, other heart diseases, and duration of mitral stensis.
Atrial Pressure
;
Cardiac Output
;
Echocardiography
;
Electrocardiography
;
Female
;
Heart Diseases
;
Humans
;
Hypertension, Pulmonary*
;
Mitral Valve
;
Mitral Valve Insufficiency
;
Mitral Valve Stenosis*
;
Pulmonary Artery
;
Vascular Resistance