A 31-year-old woman with surgically proven spinal extradural granulocytic sarcoma was examined with magnetic resonance (MR) imaging. This patient had no evidence of systemic leukemia. The signal intensities of the mass on T1-weighted and gradient echo images were higher than those of spinal cord, which were different from iso-intensity of cases reported by other authors.
Adult ; Female ; Humans ; Leukemia ; Magnetic Resonance Imaging* ; Sarcoma, Myeloid* ; Spinal Cord

For the study of correlation of CT number and fatty content of the liver, total 35 rabbits were used. Therabbits were divided into one control and three experimental groups according to the amount of carbonetetra choloride, administered 1ml, 2ml and 3ml per kg lf body weight respectively. The carbone tetrachloride wasadministered via intragastric route. CT was performed 72 hours following administration of carbone tetrachloride,and immediately prior to CT scan each rabbit was anesthetized by means of IM injection of ketamine and IV injection of succinylcholine to stop motion and respiration. CT numbers were measured and histological study forthe deposition of fat in the liver tissue was done. Also biochemical analysis of lipid in the blood and in theextraction of liver tissue was performed. Comparison of CT number with biochemical and histological data was done.The results were as follows: 1. In each experimental group, the degree of accumulation of fat in the liver was proportional to the amount of carbone tetrachloride. 2. Degree of decreaseing CT number was correlated with theincrease in the accumlation of fat in the liver. 3. In the control and experimental (1,2,3) groups, when theamount of carbone tetrachloride increased, the amount of total lipid, cholesterol and triglyceride on biochemical analysis of the liver increased. Also increase in the amount of plasma lipids on biochemical analysis and a greatdegree of increase in accumulation of fat in the liver on histological examination were see. But no changes in theamounts of phospholipid and protein on biochemical analysis of the liver were noticed. 4. Increase in the amountof total lipid could make a change in the CT number of the liver remakably(r=−0.63). As the amount of cholesteroland triglyceride increased, the CT number of the liver decreased (r=−0.61 and r=−0.76 respectively). But there wasno significant correlation between the amount of protein and phospholipid and the degree of decrease in CT number.5. Mean values of CT number in normal, grade 1, grade 2, grade 3 and grade 4 according to the degree ofhistological changes were 67.46±2.24, 58.53±3.06, 49.43±6.91, 39.49±9.69, 20.62±8.04 respectively. Thereduction of CT number was correlated with the accumulation of fat on histological examination.
Body Weight ; Carbon ; Cholesterol ; Fatty Liver ; Ketamine ; Liver ; Plasma ; Rabbits ; Respiration ; Succinylcholine ; Tomography, X-Ray Computed ; Triglycerides

A retrospective study on computed tomographic (CT) findings in 35 surgically confirmed cases of common bile duct stones was performed to analyze the characteristic CT findings. Choledocholithiasis was correctly diagnosed by CT in 33 our of 35 cases(sensitivity, 94.3%) and among these CT demonstrated calculi of high attenuation in 32 and of soft tissue density in one case. The thirty two included 23 totally calcified, 5 rim calcified and 4 laminated stones. The target sign was observed in 30 out of 33 CT positive cases (90.1%). We concluded that CT is an accurate modality in the diagnosis of common bile duct stones with its' reliable display of the calcified or the laminated stone itself and its' characteristic target sign.
Bile* ; Calculi ; Choledocholithiasis ; Common Bile Duct ; Diagnosis ; Retrospective Studies

Pulmonary Langerhans' cell histiocytosis is an uncommon granulomatous disorder of unknown cause. The authors retrospectively evaluated radiographs and computed tomographic findings of five patients with biopsy-proven pulmonary Langerhans' cell histiocytosis. The main structural abnormalities consisted of small nodules and cystic air spaces, but one case showed only pneumothorax due to bullae rupture. Its distribution has been known predominently in the upper lung fields, but in our cases, the lung lesions were distributed in the entire lung fields or predominently in the lower lung fields. We propose that pulmonary Langerhans' cell histiocytosis is extremely variable of its structural abnormalities and distribution.
Histiocytosis* ; Humans ; Lung ; Pneumothorax ; Retrospective Studies ; Rupture

PURPOSE: We performed a retrospective study to compare the accuracy between conventional CT staging and intraoperative staging for advanced gastric cancer. MATERIALS AND METHODS: Sixty patients with advanced gastric cancer were included in this study during the recent 2 year-period. All were pre- and posto- peratively diagnosed as advanced gastric cancer. CTwas performed with G E 9800 and Somatom DR3 under conventional technique in 50 and with others in 10 referred patients. The CT staging for T and N category with emphasis on incurable factor, if not resacted, were performed. And we compared the accuracy between conventional CT and intraoperative staging. The final histo-pathologic staging was used as a gold standard. RESULTS: Accuracy of CT and operation for T4(n=l7) factor is 76.9 % and 86.2 % respectively. Overestimation rate for T4 was 9.3 % by CT and 6.1% by operation, and underestimation rate for was 13.8 % and 7.7 % respectively. Accuracy of CT and operation for N (n=60) factor was 50 % and 60 % respectively. Overestimation rate for N factor was 18.3 % by CT and 18.3 % by operation, and underestimation rate for N factor was 31.7 % and 21.7 % respectively. Correct Tand IM staging was possible only in 33% by CT and 38% by intraoperative assessment. CONCLUSION: Conventional CT and intraoperative staging for incurable T/N factor in advanced gastric cancer have a potential limitations, especially for N factor. Therefore, more reliable modality or technique such as dynamic scanning by spiral CT, transabdominal or endoscopic ultrasonography should be preoperatively performed to complement infrequent errors in intraoperative staging. Furthermore, a histology-oriented surgical approach seems essential in selecting the most appropriate surgical procedure.
Complement System Proteins ; Endosonography ; Fibrinogen ; Humans ; Retrospective Studies ; Stomach Neoplasms* ; Tomography, Spiral Computed

Many diagnostic tools, which record eye movement, are available for diagnosis and treatment of the patients with impaired eye movement. Most of these tools cannot record directly the eye movement but record electrical analog signal developed when eyeball moves through electrode attached on skin or sclera. Because they need a fixation device, they may bring a patient discomfort. It is well known that digital recording device is not interfered by external noise signal and that its reproducibility is acceptable. We have developed a noninvasive, direct, and precise technique for recording eye movement and verified its reproducibility. We video-taped the horizontal and vertical eye movement and processed the captured images digitally using a image analysis program. the result showed the frequency energy of eye movement in the range within 6Hz and at 10 or 11Hz. The eye movement was observed more clearly after filtering the low frequency energy by inverse Fourier transformation. The reproducibility for measurements of total variability were as follows; vertical displacement measurements, 1.21%; horizontal displacement measurements, 0.68%. In conclusion, this new technique is easy and comfortable to examiner and patient. Its reproducibility was acceptable. Thus it may served as a substitute of conventional tools for recording eye movement.
Diagnosis ; Electrodes ; Eye Movements* ; Fourier Analysis ; Humans ; Noise ; Sclera ; Skin

Recent studies have documented that testosterone relaxes several smooth muscles by modulating K+channel activities. Smooth muscles of seminal vesicles play a fundamental role in ejaculation, which might involve testosterone. This study was aimed to assess the role of testosterone in seminal vesicular motility by studying its effects on contractile agents and on the ion channels of single vesicular myocytes in a rabbit model. The contractile responses of circular smooth muscle strips of rabbit seminal vesicles to norepinephrine (10 micrometer), a high concentration of KCl (70 mM), and testosterone (10 micrometer were observed. Single vesicular myocytes of rabbit were isolated using proteolytic enzymes including collagenase and papain. Inside-out, attached, and whole-cell configurations were examined using the patch clamp technique. The applications of 10 micrometernorepinephrine or 70 mM KCl induced tonic contractions, and 10 micrometertestosterone (pharmacological concentration) evoked dose-dependent relaxations of these precontracted strips. Various K+channel blockers, such as tetraethylammonium (TEA; 10 mM), iberiotoxin (0.1 micrometer), 4-aminopyridine (4-AP, 10 micrometer, or glibenclamide (10 micrometer rarely affected these relaxations. Single channel data (of inside-out and attached configurations) of BK channel activity were also hardly affected by testosterone (10 micrometer). On the other hand, however, testosterone reduced L-type Ca2+currents significantly, and found to induce acute relaxation of seminal vesicular smooth muscle and this was mediated, at least in part, by Ca2+current inhibition in rabbit.
4-Aminopyridine ; Calcium ; Calcium Channels ; Collagenases ; Contracts ; Ejaculation ; Glyburide ; Hand ; Ion Channels ; Male ; Muscle Cells ; Muscle, Smooth ; Norepinephrine ; Papain ; Peptide Hydrolases ; Peptides ; Relaxation ; Seminal Vesicles ; Testosterone ; Tetraethylammonium