1.Ultraviolet Light-Induced Relaxant Response in Arterial Smooth Muscles, Mediators of the Response and Effect of Calcium Modulators on the Relaxation.
Yung Hong BAIK ; Jong Keun KIM ; Yoon Il KIM ; Jongeun LEE ; Jung Chaee KANG
Korean Circulation Journal 1991;21(6):1126-1136
Effects of Ultratiolet (UV) light was studied in isolated thoracic aortae of rabbits and porcine coronary arteries. The following results were obtained. 1) Radiation of UV light did not affect both arterial rings in resting tension. 2) Both arterial preparations contracted with various vasoconstrictors (KCI,NE,PE,BayK 8644 and (+S202 etc.) were relaxed by UV light radiation in a radiation time-dependent fashion. 3) The magnitudes of the relaxation were not significantly different in both the rings with or without intact endothelium. 4) MB and LY markedldy reduced the UV light-induced relaxation in both the rings. 5) PP significantly attenuated the UV light-induced relaxation of rabbit thoracic aorta, but did not affect that of porcine coronary artery. 6) The UV Light-induced relaxation of porcine coronary artery was significantly attenuated by DT or NF, while that of rabbit thoracic aorta was not. 7) (+)S202 significantly potentiated the UV light-induced relaxation of porcine coronary artery contracted with KCI or Hist. Above results suggest that the UV light-induced relaxation of vascular smooth muscles is independent on the endothelium, and the relaxation results from primarily activation of guanylyl cyclase and is in part related to adenylyl cyclase and calcium metabolism. In adddition, a dihydropyridine calcium agonist, (+)S202, may sensitize vascular smooth muscle to the relaxing effect of UV light through some unknown mechanism.
Adenylyl Cyclases
;
Aorta, Thoracic
;
Calcium*
;
Coronary Vessels
;
Endothelium
;
Guanylate Cyclase
;
Metabolism
;
Muscle, Smooth*
;
Muscle, Smooth, Vascular
;
Rabbits
;
Relaxation*
;
Ultraviolet Rays
;
Vasoconstrictor Agents
2.Multiple hamartomas(mesenchymomas) of the unilateral chest wall in infancy: CT findings.
Myung Joon KIM ; Choon Sik YOON ; Ki Keun OH ; Jong Tae LEE ; Woo Hee JUNG
Journal of the Korean Radiological Society 1992;28(5):794-797
A case of multiple hamartomas of the unilateral chest wall in a four month old infant is presented. There have been a few reports on the CT findings of the chest wall hamartoma in infancy. We describe bone changes of the ribs and mineralization of this rare tumor on the CT scan, and the locations of two separate masses.
Hamartoma
;
Humans
;
Infant
;
Miners
;
Ribs
;
Thoracic Wall*
;
Thorax*
;
Tomography, X-Ray Computed
3.Increased frequency of sister chromatid exchanges after I therapy in lymphocytes of thyroid cancer patients.
Keun Hee CHOI ; Hee Seung BOM ; Kwang Yoon KIM ; Ji Yeul KIM ; Jung Han YOON ; Young Jong JAEGAL
Korean Journal of Nuclear Medicine 1993;27(1):118-122
No abstract available.
Humans
;
Lymphocytes*
;
Siblings*
;
Sister Chromatid Exchange*
;
Thyroid Gland*
;
Thyroid Neoplasms*
4.Results of Posterior Cruciate Retained Total Knee Arthroplasty in Patients with Flexion Deformity: In Comparison with Posterior Stabilized Type.
Yong Hoon KIM ; Keun Woo KIM ; Hak Jin MIN ; Eui Seoung YOON ; Sang Lim KIM ; Yoon Jong KIM
Journal of the Korean Knee Society 2001;13(2):142-147
No Abstract Available.
Arthroplasty*
;
Congenital Abnormalities*
;
Humans
;
Knee*
5.Utility of Multiplanar Reformation Images of Helical CT in the Evaluation of Pancreatic Diseases.
Jun Ho KIM ; Hyun Jong KIM ; Heoung Keun KANG ; Yun Hyeon KIM ; Jong Hoon YOON ; Hyeong Kil KIM
Journal of the Korean Radiological Society 1995;33(2):273-278
PURPOSE: The purpose of this study is to assess the clinical utility of multiplanar reformation images of helical CT in the evaluation of pancreatic diseases. MATERIALS AND METHODS: Helical CT scans of the pancreas were obtained in 30 patients with pancreatic diseases. Helical CT was performed with 5mm collimation at 5mm/sec table speed during rapid injection of intravenous contrast agent using power injector. After scanning, helical volume data were reconstructed at 2mm interval and then multiplanar reformation of the pancreas and adjacent structures was done. In both prospective reconstructed axial images and multiplanar reformation images, detection of pancreatic lesion, extent of lesion, and vascular and bile ductal changes were analyzed with a grading system of 1,2, 3. RESULTS: The mean grade of detection of pancreatic lesions was 2.37 in the prospective axial image and 2.83 in multiplanar reformation image, extent of diseases was 2.40 in prospective axial image and 2.97 in multiplanar reformation image, and vascular and bile ductal changes was 2.00 in the prospective axial image and 2.97 in multiplanar reformation image. All the differences were statistically significant (P<0.0001). CONCLUSION: Multiplanar reformation images of helical CT are useful in the evaluation of pancreatic diseases and especially in the demonstratibn of complex anatomic relationships between the pancreas and surrounding structures.
Bile Ducts
;
Humans
;
Pancreas
;
Pancreatic Diseases*
;
Prospective Studies
;
Tomography, Spiral Computed*
6.The Treatment of Angiofibromas Using Multiple-Drilling Method by Carbon Dioxide Laser.
Jong Keun SEO ; Sung Hwan HWANG ; Jeong Nan KANG ; Soon Kwon HONG ; Jai Kyoung KOH ; Sung Ho YOON
Korean Journal of Dermatology 2012;50(8):757-759
No abstract available.
Angiofibroma
;
Carbon
;
Carbon Dioxide
;
Lasers, Gas
7.A case of Kniest syndrome.
Yoon Jong YOO ; Ki Chan NA ; Kyeong Rae MOON ; Sang Kee PARK ; Young Bong PARK ; Keun Hong KEE
Journal of the Korean Pediatric Society 1993;36(1):138-143
The Kniest syndrome is characterized by disproportionate dwarfism and Kyphoscoliosis which may be associated with flat facies with prominent eyes, cleft palate, hearing loss, myopia and limited joint motion. The skeletal abnormalities are recognizable at birth with shortening and deformity of the extremities and stiff joints. Marked lumbar lordosis and kyphoscoliosis develop in childhood, resulting in disproportionate shortening of the trunk. We experienced a case of kniest syndrome, confirmed by clinical features, radiological features, and histological examination of cartilage. A brief review of the related literature is presented.
Animals
;
Cartilage
;
Cleft Palate
;
Congenital Abnormalities
;
Dwarfism
;
Extremities
;
Facies
;
Hearing Loss
;
Joints
;
Lordosis
;
Myopia
;
Parturition
8.Surgical Treatment of Esophageal Perforation Caused by Balloon Catheter and Expandible Metal Stent in a Benign Distal Esophageal Stricture.
Keun Nam SHIN ; Jong Hoon YOON ; Hae Hyeon SUH
Journal of the Korean Surgical Society 1998;55(2):282-289
An esophageal perforation is a condition requiring emergency treatment. Although previously spontaneous ruptures were the most common etiology, as endoscopic and radiologic diagnosis and treatment have developed recently, iatrogenic ruptures due to instrumentation have increased to become the most common cause of esophageal perforations. Generally, the treatment of esophageal stenosis is composed of esophageal dilatation using a Maloney or a Mercury dilator and medical treatment for reflux esophagitis. Recently, balloon-catheter dilatation of the esophagus has produced safe and excellent results, and self-expansible metallic stents has been very useful in controlling malignant strictures of the esophagus with low mortality and morbidity. We experienced an esophageal perforation after balloon dilatation and the insertion of a self-expanding silicone-covered Gianturco stent to the site of the esophageal stenosis which was due to reflux esophagitis. The abdomen was opened through an upper midline incision. There was a 3-cm-long longitudinal laceration on the distal esophagus which was closed transversely as with a Heinecke-Mikulicz pyloroplasty after a debridement. To reinforce the site of esophageal laceration and to prevent esophageal reflux, the gastric fundus was pulled and sutured over the esophageal sutures, and the second-layer mattress suture was made 1 cm proximal to the first sutures, including central ligaments of the diaphragm. To prevent bile reflux, we converted from a Billroth-II to a Roux- en-Y gastrojejunostomy. We followed up for 30 months and found no signs of any esophageal stenosis or gastroesophageal reflux.
Abdomen
;
Bile Reflux
;
Catheters*
;
Constriction, Pathologic
;
Debridement
;
Diagnosis
;
Diaphragm
;
Dilatation
;
Emergency Treatment
;
Esophageal Perforation*
;
Esophageal Stenosis*
;
Esophagitis, Peptic
;
Esophagus
;
Gastric Bypass
;
Gastric Fundus
;
Gastroesophageal Reflux
;
Lacerations
;
Ligaments
;
Mortality
;
Rupture
;
Rupture, Spontaneous
;
Stents*
;
Sutures
9.Staging of Advanced Gastric Cancer: Comparison of Conventional CT and Intraoperative Assessment.
Jong Sung KIM ; On Koo CHO ; Hyun Chul RHIM ; Byung Hee KOH ; Yoon Young CHOI ; O Keun BAE ; Chang Kok HAHM
Journal of the Korean Radiological Society 1994;31(2):301-305
PURPOSE: We performed a retrospective study to compare the accuracy between conventional CT staging and intraoperative staging for advanced gastric cancer. MATERIALS AND METHODS: Sixty patients with advanced gastric cancer were included in this study during the recent 2 year-period. All were pre- and posto- peratively diagnosed as advanced gastric cancer. CTwas performed with G E 9800 and Somatom DR3 under conventional technique in 50 and with others in 10 referred patients. The CT staging for T and N category with emphasis on incurable factor, if not resacted, were performed. And we compared the accuracy between conventional CT and intraoperative staging. The final histo-pathologic staging was used as a gold standard. RESULTS: Accuracy of CT and operation for T4(n=l7) factor is 76.9 % and 86.2 % respectively. Overestimation rate for T4 was 9.3 % by CT and 6.1% by operation, and underestimation rate for was 13.8 % and 7.7 % respectively. Accuracy of CT and operation for N (n=60) factor was 50 % and 60 % respectively. Overestimation rate for N factor was 18.3 % by CT and 18.3 % by operation, and underestimation rate for N factor was 31.7 % and 21.7 % respectively. Correct Tand IM staging was possible only in 33% by CT and 38% by intraoperative assessment. CONCLUSION: Conventional CT and intraoperative staging for incurable T/N factor in advanced gastric cancer have a potential limitations, especially for N factor. Therefore, more reliable modality or technique such as dynamic scanning by spiral CT, transabdominal or endoscopic ultrasonography should be preoperatively performed to complement infrequent errors in intraoperative staging. Furthermore, a histology-oriented surgical approach seems essential in selecting the most appropriate surgical procedure.
Complement System Proteins
;
Endosonography
;
Fibrinogen
;
Humans
;
Retrospective Studies
;
Stomach Neoplasms*
;
Tomography, Spiral Computed
10.MR Imaging of Intracranial Calcification; Experimental and Clinical Studies.
Heoung Keun KANG ; Jeong Jin SEO ; Yun Hyeon KIM ; Jong Hoon YOON ; Byung Jin KIM ; Sung Yeul YANG
Journal of the Korean Radiological Society 1995;32(5):703-710
PURPOSE: This study was performed to evaluate MR signal intensity(SI) of calcification and to assess the capability of MRI in detection of various intracranial calcifications. MATERIALS AND METHODS: The MR findings and ROI value of experimental model of calcium carbonate suspension according to each concentration (20, 35, 50%) and diameter (1-10 mm) and hydroxyapatite suspension according to each concentration (10, 20, 30, 40, 50%) were analyzed. A specimen of calcification in cranio-pharyngioma was analyzed for its composition by XRD(X-ray diffractometer) and ICP(inductively coupled plasma) methods. MRI of 34 patients with intracranial calcifications were retrospectively analyzed for signal intensity of the calcification and its capability to detect calcifications according to size, location, and contrast with adjacent lesion. RESULTS: The calcium carbonate phantom with larger diameter and low concentration showed lower signal intensity on T2 than TlWl. Hydroxyapatite phantom showed high signal intensity in 10-30% concentration and low signal intensity in 40-50% concentration on T1 weighted image. The 5 cases of 34 intracranial calcifications showed high signal intensity on T1 weighted image. The capability of MRI in the detection of intracranial calcifications decreased in the circumstances such as small size(<2.5mm) and intraventricular location. Although the size of calcification was small, the detection was easy in the good contrast with adjacent lesion. However, the detection of the small sized calcification was easy if the contrast with adjacent lesion was good. CONCLUSION: lntracranial calcification shows generally low signal intensity on T1 and T2 weighted image with the exception of occasional high SI on TlWl. Detection of intracranial calcification in MRI is affected by its composition, size, location, and contrast with adjcent lesion.
Calcium Carbonate
;
Durapatite
;
Humans
;
Magnetic Resonance Imaging*
;
Models, Theoretical
;
Retrospective Studies