2.A case of fetus-in-fetu.
Journal of the Korean Pediatric Society 1993;36(12):1761-1764
Fetus-in-fetu is a very rare condition in which a malformed monozygotic twin lies within the body of its fellow, usually in the retroperitoneal cavity. Today it is generally accepted that the distinction between fetus-in-fetu and teratoma is largely determined by whether an axial skeleton system is present. We experienced a 6 months female infant who was admitted to our unit because of incidental abdominal mass. a plain abdominal X-ray showed that the mass contained completely formed fetal skeletal system. It was removed by surgery. By pathologic and radiologic study of mass, We confirmed as a fetus-in-fetu. We report the case with brief review of related literatures.
Female
;
Humans
;
Infant
;
Skeleton
;
Teratoma
;
Twins, Monozygotic
3.The Role of Endorectal Ultrasonography in the Follow-up Evaluation of the Uterine Cervical Carcinomas in Intra-arterial Cisplatin Chemotherapy.
Journal of the Korean Radiological Society 1994;30(6):1135-1140
PURPOSE: lntra-arterial cisplatin infusion chemotherapy delivers higher concentration of this therapeutic agent to the limited area of cervical carcinoma. We evaluated the role of endorectal ultrasonography (ERUS) in the analysis of the tumor response to this chemotherapy. MATERIALS AND METHODS: ERUS was done in 20 patients of cervical carcinomas limited to the pelvis by rotating the 5 UHz linear arraytransducer along the reference sagittal plane in the middle of uterine cervix and vagina. We examined and compared the change of tumor size and morphology on ER US, before, during and after intra-arterial cisplatin (50 mg/m2) chemotherapy through internal lilac artery near uterine arterial branching. Colposcopy and radical hysterectomy with pelvic lymphadenectomy were performed in all patients, and ERUS findingswere compared with those findings. RESULTS: ERUS correlated well with surgery in the estimation of preoperative tumor size and morphology. Tumor reduction rate on ERUS (100-the largest area of the preoperative tumor/the largest area of the initial tumor) was as follows: more than 75% decrease of the original size in 3 patients, 75% -50% in 6 patients, 50%-25% in 8 patients, and less than 25% in 3 patients. Hyperechoic reflecting areas were noted in 4 patients, which corresponded to gaseous necrosis on postoperative pathology. CONCLUSION: ERUS is helpful to evaluate the morphologic change of cervical carcinoma limited tothe pelvis in intra-arterial cisplatin chemotherapy.
Arteries
;
Cervix Uteri
;
Cisplatin*
;
Colposcopy
;
Drug Therapy*
;
Female
;
Follow-Up Studies*
;
Humans
;
Hysterectomy
;
Lymph Node Excision
;
Necrosis
;
Pathology
;
Pelvis
;
Ultrasonography*
;
Vagina
4.The prognostic factors of the facial nerve paralysis in herpes zoster oticus.
Deok Jun KIM ; Joong Gahng KIM ; Jong Hoon KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(2):286-293
No abstract available.
Facial Nerve*
;
Herpes Zoster Oticus*
;
Herpes Zoster*
;
Paralysis*
5.Congenital Left Ventricular Diverticulum.
Jong Young KIM ; Jung Ho KIM ; Jin Gon JUN
Yeungnam University Journal of Medicine 1990;7(2):181-187
Congenital diverticulosis of the left ventricle is an extremely are rare maldevelopment. We report a 9 year old girl with probable isolated left ventricular diverticulum in whom the diagnosis was made by cross sectional echocardiography and by angiography.
Angiography
;
Diagnosis
;
Diverticulum*
;
Echocardiography
;
Female
;
Heart Ventricles
;
Humans
6.Immunohistochemical Expression of p53, E-cadherin, and nm23 Proteins in Metastatic Carcinoma of Neck Lymph Node and Corresponding Primary Carcinoma.
Jong Kook KIM ; O Jun KWON ; Byung Heon KIM
Korean Journal of Pathology 2000;34(9):615-624
This study was carried out to evaluate the immunohistochemical expressions of p53, E-cadherin, and nm23 proteins in 114 cases of metastatic carcinoma of the neck lymph node (MTLNCA) and corresponding primary carcinoma (PRCA). The positive expressions of p53, E-cadherin, and nm23 proteins were 62.3%, 58.8% and 64.0%, respectively in PRCA, and 40.4%, 38.6%, and 43.9%, respectively in MTLNCA with significant down-regulation from PRCA to MTLNCA (p<0.05). The down-regulation was correlated with female gender, moderate and poor differentiation, and adenocarcinoma in p53 protein, female gender, respiratory and gastrointestinal carcinoma in E-cadherin protein, and female gender, respiratory carcinoma, moderate differentiation, and squamous cell carcinoma in nm23 protein (p<0.05). There was no significant relationship among expressions of p53, E-cadherin, and nm23 proteins (p<0.05). In conclusion, these results suggest that the expressions of p53, E-cadherin, and nm23 proteins seem to be down-regulated from PRCA to MTLNCA and this down-regulation may play a role in invasion and metastasis.
Adenocarcinoma
;
Cadherins*
;
Carcinoma, Squamous Cell
;
Down-Regulation
;
Female
;
Humans
;
Lymph Nodes*
;
Neck*
;
Neoplasm Metastasis
7.Primary Endodermal Sinus Tumor In The Sacrococcygium.
Jong In KIM ; Jin YANG ; Ik Jun LEE ; Young Hyun KWAK
Journal of the Korean Pediatric Society 1983;26(6):584-588
No abstract available.
Endoderm*
;
Endodermal Sinus Tumor*
8.Endorectal Coli MRI in the Local Staging of Clinically Organ Confined Prostate Cancer.
Yong Jae KIM ; Jun Hyuk HONG ; Han Jong AHN
Korean Journal of Urology 2000;41(9):1057-1062
No abstract available.
Magnetic Resonance Imaging*
;
Prostate*
;
Prostatic Neoplasms*
9.Effect of Sequential Embryo Transfer in vitro Fertilization.
Byeong Jun JUNG ; Jong Sik KIM ; Hyun Jin SONG
Korean Journal of Fertility and Sterility 2000;27(1):75-82
OBJECTIVE: The objective of this study is to nfluence of sequential embryo transfers in an invitro fertilization was examined. METHOD: After in vitro fertilization, a maximum of 6 fertilized oocytes was enrolled in this study. At day 3 after an oocytes retrieval, embryos with good quality were transferred (mean 4.9), remaining embryos (mean 2.0/cycle) were cryopreserved at blastocyst stage (Group 1). At day 5 after oocytes collection, second a embryos had reached the blastocyst stage (Group 2) using P1 supplemented with 10 SSS and 30% Follicular fluid. No statistical difference in the pregnancy rate could be seen between the group without a second embryo transfer (n=21; 28.6%) and the group with a second transfer (n=52; 28.8%). RESULTS: The incidence of multiple pregnancy rate per embryo transfer was not statistically different between both group and no high-rank multiple pregnancy (greater than triplete) were observed (o.9%, 15.4%, respectively, p=0.74, chi2). Out of 114 cycles (506 embryos) cultured embryos in group 2, 52 cycles (159 embryos, 29.8%) reached the blastocyst stage. CONCLUSION: The second transfer did not have a significant effect on the pregnancy rate. The most important factor for the pregnancy seems to be the quality of the embryos transferred on day 3 following oocyte retrieval. We recommend embryo transfer is performed only one, day 2~3 or D5.
Blastocyst
;
Embryo Transfer*
;
Embryonic Structures*
;
Female
;
Fertilization
;
Fertilization in Vitro*
;
Follicular Fluid
;
Incidence
;
Oocyte Retrieval
;
Oocytes
;
Pregnancy
;
Pregnancy Rate
;
Pregnancy, Multiple
10.Absorption, Excretion and Antioxidative Effect of Rebamipide on Reproductive Organ.
Jong Il KIM ; Hyun Jun PARK ; Nam Cheol PARK
Korean Journal of Fertility and Sterility 2005;32(4):301-314
OBJECTIVE: Rebamipide is a propionic acid derivative that has an action of the inhibition of superoxide production and removal of hydroxyl radical with the sperm incubation and cryopreservation. In the present study, to investigate whether rebamipide is useful to treat male infertility and sterility, the author observed the antioxidative effects in patient with male infertility and also examined its absorption and distribution in rat genital organ. METHODS: To measure the distribution of rebamipide in reproductive organ in the rat, carbon indicated rebamipide, 14C-OPC-12759, was orally administered to 10 Spraque-Dawley rats and its organ concentration in serum, liver, kidney, stomach, duodenum, colon, urinary bladder, seminal vesicle, epididymis and testicle were measured each time after 0.5, 1, 2, 4, 8 and 24 hours by using HPLC fluorescent method. The concentrations in semen were measured by HPLC fluorescent method in a sample of 50 infertile males who took 900 mg of rebamipide daily for 3 months. To measure the antioxidative effect and fertility rate for 3 months, each month before and after the treatment, sperm motility, vitality, the oxygen free radical formation, level of peroxidation, fetilizing capacity of semen sample which were obtained from infertile male patients by masturbation after at least 48 hours abstinence were analyzed by computer assisted semen analyzer, eosin-nigrosin stain, chemiluminescence, thiobarbituric acid method and hypo-osmotic swelling test. Simultaneously in a sample that wanted baby, both pregnancy and delivery were researched. RESULTS: The 14C-OPC-12759 concentration in the body of white rats was highest in gastrointestinal organ like stomach, smal intestine and duodenum and followed by genital organ like seminal vesicle, testis and epididymis. The rebamipide concentration in semen of infertile males was 220.77+/-327.84 ng/mL (SD) which showed a large deviation but it was higher than serum which was 126+/-76 ng/mL (SD). In the infertile males, after the treatment with rebamipide, the level of seminal reactive oxygen species (ROS) and lipid peroxidation have significantly decreased in duration of the treatment (p<0.05) and sperm vitality and fertilizing capacity except sperm motility significantly improved on post treatment of 2~3 months (p<0.05). Out of the 41 cases who hoped for pregnancy, 15 cases (36.6%) became pregnant and 12 cases had childbrith, 2 cases had miscarriage and one case is ongoing. The side effect was observed in 1 case (2%) which experienced diarrhea but it was lost spontaneously. CONCLUSIONS: We conclude from this study that rebamipide showed relatively high tendancy of absorption and excretion in the genital organ. In infertile males who had elevated ROS in semen, by specifically inhibiting the cell damage from the antioxidation, a way to preserve sperm motility, vitality and fertilizing capacity was confirmed.
Abortion, Spontaneous
;
Absorption*
;
Animals
;
Birth Rate
;
Carbon
;
Chromatography, High Pressure Liquid
;
Colon
;
Cryopreservation
;
Diarrhea
;
Diethylpropion
;
Duodenum
;
Epididymis
;
Female
;
Genitalia
;
Hope
;
Humans
;
Hydroxyl Radical
;
Infertility
;
Infertility, Male
;
Intestines
;
Kidney
;
Lipid Peroxidation
;
Liver
;
Luminescence
;
Male
;
Masturbation
;
Oxygen
;
Pregnancy
;
Rats
;
Reactive Oxygen Species
;
Semen
;
Seminal Vesicles
;
Sperm Motility
;
Spermatozoa
;
Stomach
;
Superoxides
;
Testis
;
Urinary Bladder