1.Clinical experience of lomefloxacine(SC-47111, NY-198) in treatment of urinary tract infection.
Soo Cheol LEE ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Infectious Diseases 1992;24(1):37-43
No abstract available.
Urinary Tract Infections*
;
Urinary Tract*
2.Normal Variation of Focal T2 Hyperintensities in Anterior Parietal Periventricular white Matter: Another 'Terminal Zones of IV!yelination'.
Jong Hwa LEE ; Jong Oag PARK ; Je Ho WOO ; Tae Sung KI ; Don Young LEE
Journal of the Korean Radiological Society 1994;30(5):807-810
PURPOSE: It has been known that there are several areas of T2 hyperintensities in normal white matter of brain, such as terminal zones of myelination, ependymitis granularis, ones of posterior internal capsule, and perivascular space. The aim of our study is to demonstrate another region of T2 hyperintensities in normal pediatric age group. MATERIALS AND METHODS: We have studied brain MR for 10 normal volunteers and 35 patients without having intracranial lesions in pediatric age group(3-19 years). RESULTS: In 5 among 45 cases, focal T2 hyperintensities were seen in the parietal periventricular white matter beneath the postcentral gyri. They were noted as poorly defined, 5--10mm sized areas of increased signal intensities on T2 weighted axial images. They were also characterized by bilateral, posteromedially oriented, short band-like or oval areas. Interestingly, they were directly continuous with the T2 hyperintensity of posterior internal capsule. In spite of the relatively high frequency in the pediatric population as in our study, this finding has not been reported in the asymptomatic adults. CONCLUSION: The results show that the bilateral anterior parietal hyperintense areas may be another terminal zones of delayed myelination affecting the parietopontine tract. They should be differentiated from pathologic T2 hyperintensities by their characteristic findings.
Adult
;
Brain
;
Healthy Volunteers
;
Humans
;
Internal Capsule
;
Myelin Sheath
;
Rabeprazole*
3.Immunohistochemical Demonstration of C-erbB-2 Oncoprotein Expression in Transitional Cell Carcinoma of the Bladder: Correlative Study with Tumor Grade, Stage, Proliferating Cell Nuclear Antigen Expression, Nucleolar Organizer Regions Per Nucleus, and Flow.
Ji YOO ; Jun CHEON ; Han Kyeum KIM ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Urology 1994;35(8):817-826
C-erbB-2 oncoprotein has been known to act as growth factor receptor responsible for the regulation of cellular growth, proliferation and differentiation and has been demonstrated in a number of cancers by immunohistochemical as well as matrix blotting techniques. Breast and ovarian cancer patients, whose tumor cells have amplification or overexpression of this oncoprotein, have been suggested to have worse prognosis. Yet, there are only a few studies on c-erbB-2 oncoprotein expression in transitional cell carcinoma(TCC) of the bladder. The aim of this study was to examine c-erbB-2 oncoprotein expression in bladder cancer to assess its potential as a useful prognostic marker in transitional cell carcinoma of the bladder. Deparaffinized tumor specimens from 42 patients with TCC of the bladder and 3 normal bladder tissue specimens were utilized. C-erbB-2 oncoprotein expression was detected by immunohistochemical analysis and then correlated with conventional prognostic variables such as histologic tumor grade, stage and DNA ploidy. In addition, we related the expression of c-erbB-2 oncoprotein to indicators of cellular proliferative activities such as proliferating cell nuclear antigen(PCNA), mean number of silver nucleolar organizer regions(AgNORs) per nucleus, flow cytometric S-phase fraction(CPF) and proliferation index(PI). The incidence of c-erbB-2 oncoprotein expression in Ash grade IV TCC of bladder was higher than that in Ash grade II and III (Chi-square test, p<0.05). The incidence of positive immunoreaction was higher in cases with muscle invasion and metastasis than in superficial tumors with statistical significance(p<0.05). In addition, statistical significant correlation was noted between c-erbB-2 oncoprotein expression and PCNA expression rate. But there were no significant differences in c-erbB-2 oncoprotein expression to DNA ploidy, PI nor SPF by flow cytometry and mean number of AgNORs per nucleus. The results of this study suggests that the c-erbB-2 oncoprotein together with other predictive parameters may serve to provide a phenotypic profile which permits more accurate forecasting of bladder cancer behavior and may prove to be useful in the future as an important guide to specific anti-tumor therapy.
Breast
;
Carcinoma, Transitional Cell*
;
DNA*
;
Flow Cytometry
;
Forecasting
;
Humans
;
Incidence
;
Neoplasm Metastasis
;
Nucleolus Organizer Region*
;
Ovarian Neoplasms
;
Ploidies*
;
Prognosis
;
Proliferating Cell Nuclear Antigen*
;
Silver
;
Urinary Bladder Neoplasms
;
Urinary Bladder*
4.The Assessment of Carfecillin in Acute Uncomplicated Urinary Tract Infection.
Korean Journal of Urology 1982;23(5):649-654
Fifty cases of acute uncomplicated urinary tract infection were selected and 3.0gm of Carfecillin was given for one day in two doses. The clinical and bacteriological results were compared with the results of 32 cases of the urinary tract infection who was given 200 mg of Doxycycline daily for 7 days. Of 50 patients receiving Carfecillin only 23 cases were sensitive to Carfecillin though 32 patients receiving Doxycycline were all sensitive to Doxycycline on prior to treatment urine culture. Carfecillin was effective in 34 cases among 38 cases of cystitis while Doxycycline was effective in 12 cases among 21 cases of cystitis. In 7 out of 12 cases of pyelonephritis Carfecillin was effective, while Doxycycline was effective in 9 out of 11 cases. Among 23 cases which were sensitive to Carfecillin, Carfecillin single day treatment was effective in 13 out of 17 cases of cystitis and 4 out of 6 cases of pyelonephritis. Both Carfecillin and Doxycycline showed good efficacy to E-coli, Staphylococcus aureus, Klebsiella, Streptococcus and Enterobacter. A single day treatment of Carfecillin was as effective as a conventional treatment of Doxycycline for the treatment of uncomplicated urinary tract infections.
Carfecillin*
;
Cystitis
;
Doxycycline
;
Enterobacter
;
Humans
;
Klebsiella
;
Pyelonephritis
;
Staphylococcus aureus
;
Streptococcus
;
Urinary Tract Infections*
;
Urinary Tract*
5.Vesical Endometriosis : A Review and 1 Case Report.
Ho Hyeon JEONG ; Je Jong KIM ; Jae Heung CHO ; Sung Kun KOH
Korean Journal of Urology 1988;29(1):162-164
The term endometriosis refers to ectopic endometriume. It most often involves the pelvic organs, including ovaries, broad and round ligaments, fallopian tubes, cervix, vagina and the pouch of Douglas. We report a case of vesical endometriosis in a 4- year old female patient and review literature. Segmental resection of this mass with involved bladder resulted in cure and this lesion was confirmed histologically as endometriosis of the bladder.
Cervix Uteri
;
Endometriosis*
;
Endometrium
;
Fallopian Tubes
;
Female
;
Humans
;
Ovary
;
Round Ligament of Uterus
;
Urinary Bladder
;
Vagina
6.A Clinical Observation of Epididymal Tuberculosis Mimicking the Symptoms and Signs of Acute Epididymitis.
Ho Hyeon JEONG ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Urology 1988;29(1):129-132
A clinical observation was undertaken on 7 cases of epididymal tuberculosis mimicking the symptoms and signs of acute epididymitis and 24 cases of all tuberculous epididymitis which were seen during the period from September 1983 to July 1987. The results obtained were as follows. 1. A total of 7 cases of epididymal tuberculosis mimicking the symptoms and signs of acute epididymitis corresponds to 29% of epididymal tuberculosis(24 cases). 2. The highest occurrence was observed in the age of 30 to 39(5 cases). 3. Lateralization showed 5 cases in the right, 2 cases in the left and none in both. 4. Presenting symptoms and signs were painful scrotal swelling in all 7 cases, fever 4 cases, tender epididymal nodule 4 cases and local heating 2 cases but beading of vas and scrotal fistula was not found. 5. In urine examination, pyuria was observed in 5 cases, hematuria in 1 case and no tubercle bacilli was observed. 6. Among 7 cases, we observed that epididymal tuberculosis were associated with pulmonary tuberculosis, active or inactive, in 5 cases and renal tuberculosis in 1 case.
Epididymitis*
;
Fever
;
Fistula
;
Heating
;
Hematuria
;
Hot Temperature
;
Male
;
Pyuria
;
Tuberculosis*
;
Tuberculosis, Pulmonary
;
Tuberculosis, Renal
7.The results of modified double layer vasovasostomy.
Ji YOO ; Jeong Gu LEE ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Fertility and Sterility 1991;18(2):233-235
No abstract available.
Vasovasostomy*
8.The Role K+ channel and the Effect of K+ channel Opener in the Relaxation of Vaginal Smooth Muscle.
Hong Seok PARK ; Heung Jae PARK ; Du Geon MOON ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Urology 2000;41(8):968-975
No abstract available.
Muscle, Smooth*
;
Relaxation*
9.The prognostic significance of expression of proliferating cell nuclear antigen(PCNA) in prostatic adenocarcinoma.
Joon CHUN ; Je Jong KIM ; Han Kyum KIM ; In Sun KIM ; Sung Kun KOH
Journal of the Korean Cancer Association 1993;25(6):947-955
No abstract available.
Adenocarcinoma*
10.Changes in Serum Electrolyte Following Transurethral Resection of the Prostate When 1.5% Glycine Solution and 5% Dextrose-Water Solution are Used as Irrigants.
Gil Ho LEE ; Je Jong KIM ; Sung Kun KOH
Korean Journal of Urology 1988;29(1):117-122
Transurethral resection syndrome are caused by the sudden intravascular absorption of large volumes of the irrigating solution which are used during transurethral surgery. It relates to many determining conditions of the patient postoperatively. We studied changes in serum electrolyte following transurethral resection of prostate in 61 patients used 5% Dextrose-Water solution as the irrigant and 46 patients used 1.5% glycine as the irrigant of benign prostatic hypertrophy. We divided the patients into group I and II. group I : those were given 5% Dextrose-Water solution as the irrigant. group II : those were given 1.5% glycine as the irrigant. Change in serum ammonia was obtained in 19 patients of group II. Following results were obtained. 1. Operation time, resected weight and amount of irrigant between group I and II showed no difference, statistically. 2. Serum sodium concentration was decreased in 42 cases of group I (range : 1-20mEq/L, mean : 5.0mEq/L). 3. Serum sodium concentration was decreased in 31 cases of group II (range : 1-18mEq/L, mean : 6.0mEq/L). These changes in serum concentration between group I and group II showed no significant difference, statistically. 4. Change in serum sodium concentration in the group I showed no significant correlation with operation time, resected weight and amount of irrigation. 5. Change in serum sodium concentration in the group II showed no significant correlation with operation time, resected weight and amount of irrigation. 6. Serum ammonia concentration was increased in 10 patients of 19 patients in group II (range : 5-100ug/dl, mean : 42ug/dl).
Absorption
;
Ammonia
;
Glycine*
;
Humans
;
Prostate*
;
Prostatic Hyperplasia
;
Sodium
;
Transurethral Resection of Prostate