No abstract available.
Frontal Sinus*

Real-time ultrasongraphy is a simple, accurate, noninvasive and potentially valuable means of studying gallbladder size and emptying. The authors calculated ultrasonographically the ejection fraction of 80 cases of normally functioning gallbladder on oral cholecystography, from June 1983 to April 1984, at the department of radiology, Hangang Sacred Heart Hospital. The results were obtained as follows; 1. Ultrasongraphic Ejection Fraction at 30 minutes after the fatty meal was 73.1+-16.85. 2. There was no significant difference in age and sex, statistically.
Cholecystography ; Gallbladder ; Heart ; Meals

Although the peritoneum is rare site for a primary neoplasm, certain malignant neoplasms may arise from it. A case of 63-year-old woman who had a serous papillary carcinoma of peritoneal origin is reported. Extraovarian peritoneal serous papillary carcinoma was characterized by ascites, malignant washings, and omental involvement with bulky infiltration and/or multiple tumor nodules. The symptoms caused by diffuse spreading of the neoplasm over the peritoneum are the most important manifestation for clinical diagnosis of malignant primary neoplasm of peritoneum, especially serous papillary carcinoma. This behaving tumor was at least partially responded to therapy. In this report, we describe a case of serous papillary carcinoma of peritoneum carring on proper management with brief review.
Ascites ; Carcinoma, Papillary* ; Diagnosis ; Female ; Humans ; Middle Aged ; Peritoneum*

OBJECTIVES: In the current study, we investigated the general characteristics of suicide attempters and attempted to determine factors contributing to suicide attempt by analyzing severe suicide ideation and intent. METHODS: This study analyzed medical records of suicide attempters who visited the emergency departments. Data were collected from 7 university hospitals nationwide. As an evaluation measure of suicide intent, we used Suicide Intent Scale (SIS). Colombia Suicide Severity Rating Scale (C-SSRS) was applied for assessment of severity and intensity of suicide idea and lethality of suicide behavior. RESULTS: Male gender, old age and living alone group showed higher SIS score. Male gender, low income, and having psychiatric diagnosis or suicide history group showed a high score on the severity subscale of suicide ideation of C-SSRS. Old age, low income, and having psychiatric diagnosis showed a high score on the intensity subscale of suicide ideation of C-SSRS. Actual lethality scale of C-SSRS was high in male gender and old age group. Severity and intensity of suicide ideation and suicide intent showed positive correlation with actual lethality of suicide behavior. CONCLUSION: Male gender, old age, living alone, psychiatric diagnosis, and suicide history were risk factors affecting severity and intensity of suicide ideation and intent of suicide. Severity and intensity of suicide ideation and intent are positively related to lethality of suicide behavior.
Colombia ; Emergency Service, Hospital ; Hospitals, University ; Humans ; Male ; Medical Records ; Mental Disorders ; Risk Factors ; Suicide*

Vibrio parahaemolyticus is a gram-negative halophilic organism commonly associated with outbreaks of acute gastroenteritis which also sometimes causes serious wound infection. It is an uncommon cause of bacteremia. We have experienced a case of bacteremia due to Vibrio parahaemolyticus in a 59-year old man who initially presented with edema and dyspnea. He was diagnosed as liver cirrhosis, gastric cancer, and hepatoma. On hospital day 13, Vibrio parahaemolyticus was isolated from blood culture. The isolate showed typical cultural and biochemical characteristics such as salt tolerance and did not ferment lactose. The isolate was intermediate to ampicillin but susceptible to other agents.
Ampicillin ; Bacteremia* ; Carcinoma, Hepatocellular ; Disease Outbreaks ; Dyspnea ; Edema ; Gastroenteritis ; Humans ; Lactose ; Liver Cirrhosis ; Middle Aged ; Salt-Tolerance ; Stomach Neoplasms ; Vibrio parahaemolyticus* ; Vibrio* ; Wound Infection

No abstract available.
Epinephrine* ; Skin* ; Transplants*

In recent years, early intervention is the paradigm in psychosis treatment. The logic of early intervention paradigm is based on the view that the earliest possible detection and intervention for psychosis will deliver the best outcome for patients. Therefore, in recent decades, most of studies focused on indentifying people with psychosis as early as possible, reducing the duration of untreated psychosis. However, while there are well documented and sometimes serious side effects associated with antipsychotic medication in the short-term, the iatrogenic risks of atypical antipsychotic medication are underscored. Furthermore, against this paradigm, the recent of longitudinal studies of schizophrenia suggest a new paradigm shift in treatment timing of psychosis. In this respect, this case which showed symptom remission after conversion into schizophrenia in early psychosis suggests wondering about the time of treatment. Similar cases have not been reported. And review of the effects of timing, in fact, has yet to be done. If similar cases would be reported in the future more, treatment timing may be the next paradigm shift in the therapeutics of early psychosis.
Antipsychotic Agents ; Early Intervention (Education) ; Humans ; Logic ; Longitudinal Studies ; Psychotic Disorders* ; Schizophrenia*

OBJECTIVE: A considerable proportion of suicide attempts are the result of sudden desires. Understanding such impulsive suicide attempts is necessary for effective interventions. We evaluated the impulsivity of suicide attempters treated in emergency rooms. The aim of the study was to identify the characteristics of impulsive suicide attempts by comparing these individuals to those who attempted to commit suicide in a non-impulsive manner. METHODS: This study analyzed suicide attempters who visited the emergency departments of seven selected university hospitals. A total of 269 medical records in which impulsivity of suicide attempt were confirmed were subject to be analyzed. The impulsivity of the suicide attempt was examined using a summative score of items 6 and 15 on the Suicide Intent Scale. RESULTS: A total of 48.0% of the participants were impelled by sudden inclinations to attempt suicide. Impulsive attempters were younger, unmarried and less physical illness than non-impulsive attempters, whereas no significant differences were found on psychiatric history and previous suicide history. Impulsive suicide attempters had suicide ideations that were not as severe (χ2=55.33, p<0.001) or intense (t=-8.38, p<0.001) as their counterparts'. Furthermore, medical results of impulsive suicide attempts were better than non-impulsive suicide attempts (t=-3.77, p<0.001). CONCLUSION: The results suggested that a considerable proportion of suicide attempts were the result of sudden inclinations. Impulsive attempts were made in relatively earlier stages of suicide ideation; consequently, they have less intent than non-impulsive attempts.
Emergencies* ; Emergency Service, Hospital* ; Hospitals, University ; Humans ; Impulsive Behavior ; Korea* ; Medical Records ; Single Person ; Suicide*

PURPOSE: Aberrant expression of the c-myb gene is often detected in transformed leukemic cells. Inhibition of c-myb expression by antisense oligos could be an effective way to abort rapid growth of leukemic cells. Developing stable antisense oligos combined with enhanced delivery into cells would be of great use in developing an effective anti-cancer molecular agent. MATERIALS AND METHODS: Selection of target sites was carried out by employing computer simulation of mRNA secondary structures. Multiple antisense oligo sequences were adjoined and AS-oligos were then covalently closed to evade exonuclease activities. C-myb antisense oligos with a novel structure were complexed with cationic liposomes and used to treat HL-60 leukemic cells. RESULTS: We developed covalently closed antisense oligos which harbor four adjoined antisense sequences. The c-myb antisense oligos were found to be exceptionally stable and effective in specifically ablating c-myb mRNA. The antisense oligos were able to inhibit growth of leukemic cell line (HL-60) by about 80%. Antisense effect was more pronounced when the cells were treated twice with the antisense oligos at lower concentrations. CONCLUSION: The novel covalently closed antisense oligo (CMAS-oligos) was found to be effective and exceptionally stable, Growth of HL-60 was significantly inhibited, showing a rational way to develop an effective molecular anti-cancer agent.
Cell Line ; Computer Simulation ; Genes, myb ; Liposomes ; Oligonucleotides, Antisense* ; RNA, Messenger

This review article aims to reveal the meaning and importance of economic evaluation in Korean mental health sector. The global burden of neuropsychiatric disorders, as measured by loss of disability-adjusted life years (DALYs), is estimated very high, irrespective of low mortality. There are several methods for such economic evaluation, including cost-effectiveness analysis (CEA), cost-utility analysis (CUA), and cost-benefit analysis (CBA), but there is still a paucity of such studies in the mental health sector. Economic evaluations of mental health in Korea can provide a rational basis to plan a national health policy regarding the global burden of diseases caused by psychiatric disorders.
Cost-Benefit Analysis ; Health Policy ; Korea ; Mental Health