1.Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study
Hyun Jung LIM ; Man Hoon HAN ; Eun Hye LEE ; Dong Hyuk EUN ; Jun Young KIM ; Weon Ju LEE ; Seok Jong LEE ; Do Won KIM ; Tae In PARK ; Sang Hyun KIM ; Yong Hyun JANG
Annals of Dermatology 2020;32(1):31-37
BACKGROUND:
Based on clinical and genetic differences, atopic dermatitis (AD) and psoriasis have been classified in two different diseases, but recently, some authors regarded them as in one spectrum. The histological similarities including epidermal hyperplasia between chronic stages of AD and psoriasis supports the presence of two diseases in one spectrum.
OBJECTIVE:
We investigated clinical and immunohistopathological characteristics of adult Korean patients with AD showing psoriasiform chronic dermatitis on histopathology.
METHODS:
In total, 59 Korean patients with chronic AD were enrolled. Clinical, laboratory, and histopathological features were compared between AD patients with psoriasiform features and those with non-psoriasiform chronic dermatitis features on histology. In addition, immunohistopathological characteristics were analyzed using antibodies for key regulatory and effector cytokines in psoriasis.
RESULTS:
Fifteen patients (25.4%) showed a more “psoriasiform†histological appearance. The lesions in patients with psoriasiform features often showed clearer boundaries and noticeable scaling. The interleukin (IL)-23 expression in the psoriasiform chronic dermatitis group was not different from that in the psoriasis group, but the IL-17 expression was less than that in the psoriasis group. In the case of IL-12, multiple dermal inflammatory cells with dendrites were stained in the psoriasiform chronic dermatitis group compared with the 2 other non-psoriasiform subgroups.
CONCLUSION
The results suggest that IL-12 secreted from dermal inflammatory cells might be one of the important factors associated with the formation of psoriasiform features in chronic AD. However, further studies are required to better define the specific role of IL-12.
2.Clinical Investigation on Preadolescent Acne
Dong Hyuk EUN ; Jun Young KIM ; Yong Hyun JANG ; Seok Jong LEE ; Weon Ju LEE
Annals of Dermatology 2019;31(2):249-251
No abstract available.
Acne Vulgaris
3.Minimally invasive surgery for radical hysterectomy in women with cervical cancer: Korean Society of Gynecologic Oncology, Korean Society of Obstetrics and Gynecology, and Korean Society of Gynecologic Endoscopy and Minimally Invasive Surgery position statement
Miseon KIM ; Tae Wook KONG ; Sunghoon KIM ; Seung Cheol KIM ; Yong Beom KIM ; Jae Weon KIM ; Jeong Yeol PARK ; Dong Hoon SUH ; Seung Hyuk SHIM ; Keun Ho LEE ; Sung Jong LEE ; Jae Kwan LEE ; Myong Cheol LIM
Journal of Gynecologic Oncology 2019;30(5):e104-
On the basis of emerging data and the current understanding of minimally invasive surgery (MIS) for radical hysterectomy (RH) in women with cervical cancer, the Korean Society of Gynecologic Oncology, Korean Society of Obstetrics and Gynecology, and Korean Society of Gynecologic Endoscopy and Minimally Invasive Surgery support the following recommendations: • According to the recently published phase III Laparoscopic Approach to Cervical Cancer (LACC) trial—a prospective randomized clinical trial—disease-free survival and overall survival rates of MIS RH are significantly lower than those of open RH. • Gynecologic oncologists should be aware of the emerging data on MIS RH for early-stage cervical cancer. • The results of the LACC trial, together with institutional data, should be discussed with patients before choosing MIS RH. • MIS RH should be performed for optimal candidates according to the current practice guidelines by gynecologic oncologists who are skilled at performing MIS.
Endoscopy
;
Female
;
Gynecology
;
Humans
;
Hysterectomy
;
Laparoscopy
;
Laparotomy
;
Minimally Invasive Surgical Procedures
;
Obstetrics
;
Prospective Studies
;
Survival Rate
;
Uterine Cervical Neoplasms
4.Tinea Faciei in a Mother and Daughter Caused by Arthroderma benhamiae.
Weon Ju LEE ; Dong Hyuk EUN ; Yong Hyun JANG ; Seok Jong LEE ; Yong Jun BANG ; Jae Bok JUN
Annals of Dermatology 2018;30(2):241-242
No abstract available.
Arthrodermataceae*
;
Humans
;
Mothers*
;
Nuclear Family*
;
Tinea*
5.A Case of Phaeohyphomycosis on the Wrist: Identification of Exophiala spinifera in Korea.
Weon Ju LEE ; Dong Hyuk EUN ; Yong Hyun JANG ; Seok Jong LEE ; Yong Jun BANG ; Jae Bok JUN
Annals of Dermatology 2018;30(2):232-233
No abstract available.
Exophiala*
;
Korea*
;
Phaeohyphomycosis*
;
Wrist*
6.The Polyonychia and Distal Phalangeal Bone Underdevelopment on Right Second Toe
Dong Hyuk EUN ; Jun Hong PARK ; Han Jin JUNG ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM ; Weon Ju LEE
Annals of Dermatology 2018;30(1):105-106
No abstract available.
Toes
7.Primary Angiosarcoma of the Skin Presenting as Mild Erythema.
Sun Young MOON ; Dong Hyuk EUN ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM ; Weon Ju LEE
Annals of Dermatology 2017;29(6):809-810
No abstract available.
Erythema*
;
Hemangiosarcoma*
;
Skin*
8.A Case of Fonsecaea monophora Infection.
Weon Ju LEE ; Dong Hyuk EUN ; Jun Hong PARK ; Yong Hyun JANG ; Seok Jong LEE ; Do Won KIM ; Yong Jun BANG ; Jae Bok JUN
Korean Journal of Medical Mycology 2017;22(3):141-143
No abstract available.
9.Practice guidelines for management of cervical cancer in Korea: a Korean Society of Gynecologic Oncology Consensus Statement.
Myong Cheol LIM ; Maria LEE ; Seung Hyuk SHIM ; Eun Ji NAM ; Jung Yun LEE ; Hyun Jung KIM ; Yoo Young LEE ; Kwang Beom LEE ; Jeong Yeol PARK ; Yun Hwan KIM ; Kyung Do KI ; Yong Jung SONG ; Hyun Hoon CHUNG ; Sunghoon KIM ; Jeong Won LEE ; Jae Weon KIM ; Duk Soo BAE ; Jong Min LEE
Journal of Gynecologic Oncology 2017;28(3):e22-
Clinical practice guidelines for gynecologic cancers have been developed by academic society from several countries. Each guideline reflected their own insurance system and unique medical environment, based on the published evidence. The Korean Society of Gynecologic Oncology (KSGO) published the first edition of practice guidelines for gynecologic cancer treatment in late 2006; the second edition was released in July 2010 as an evidence-based recommendation. The Guidelines Revision Committee was established in 2015 and decided to develop the third edition of the guidelines in an advanced format based on evidence-based medicine, embracing up-to-date clinical trials and qualified Korean data. These guidelines cover strategies for diagnosis and treatment of primary and recurrent cervical cancer. The committee members and many gynecologic oncologists derived key questions through discussions, and a number of relevant scientific literature were reviewed in advance. Recommendations for each specific question were developed by the consensus conference, and they are summarized here, along with the details. The objective of these practice guidelines is to establish standard policies on issues in clinical practice related to the management in cervical cancer based on the results in published papers to date and the consensus of experts as a KSGO Consensus Statement.
Committee Membership
;
Consensus*
;
Diagnosis
;
Drug Therapy
;
Evidence-Based Medicine
;
Insurance
;
Korea*
;
Uterine Cervical Neoplasms*
10.Is there an agreement among the items of the Korean physical therapist licensing examination, learning objectives of class subjects, and physical therapists' job descriptions?.
Min Hyeok KANG ; Oh Yun KWON ; Yong Wook KIM ; Ji Won KIM ; Tae Ho KIM ; Tae Young OH ; Jong Hyuk WEON ; Tae Sik LEE ; Jae Seop OH
Journal of Educational Evaluation for Health Professions 2016;13(1):3-
PURPOSE: To determine the agreement among the items of the Korean physical therapist licensing examination, learning objectives of class subjects, and physical therapists' job descriptions. METHODS: The main tasks of physical therapists were classified, and university courses related to the main tasks were also classified. Frequency analysis was used to determine the proportions of credits for the classified courses out of the total credits of major subjects, exam items related to the classified courses out of the total number of exam items, and universities that offer courses related to the Korean physical therapist licensing examination among the surveyed universities. RESULTS: The proportions of credits for clinical decision making and physical therapy diagnosis-related courses out of the total number credits for major subjects at universities were relatively low (2.06% and 2.58%, respectively). Although the main tasks of physical therapists are related to diagnosis and evaluation, the proportion of physiotherapy intervention-related items (35%) was higher than that of examination and evaluation-related items (25%) on the Korean physical therapist licensing examination. The percentages of universities that offer physical therapy diagnosis and clinical decision making-related courses were 58.62% and 68.97%, respectively. CONCLUSION: Both the proportion of physiotherapy diagnosis and evaluation-related items on the Korean physical therapist licensing examination, and the number of subjects related to clinical decision making and physical therapy diagnosis in the physical therapy curriculum, should be increased to ensure that the examination items and physical therapy curriculum reflect the practical tasks of physical therapists.
Clinical Decision-Making
;
Curriculum
;
Diagnosis
;
Humans
;
Job Description*
;
Korea
;
Learning*
;
Licensure*
;
Physical Therapists*

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