1.Embryonal Rhabdomyosarcoma of the Biliary Tree: A Case Report.
Ki Nam LEE ; Duck Hwan CHUNG ; Kyung Jin NAM ; Jong Young OH ; Byung Ho PARK ; Jong Chul CHOI
Journal of the Korean Radiological Society 1995;32(4):639-642
Rhabdomyosarcoma are reportedly the most common soft tissue sarcoma occuring in childhood, but the biliary tree is a rare site of origin for this tumor. Recently we experienced a case of embryonal rhabdomyosarcoma of the biliary tree in a 30-month-old child. UItrasonography showed hypoechoic mass filling the dilated left. intrahepatic & extrahepatic bile ducts, and CT showed hypodense mass with heterogeneous enhancement after contrast infusion. Intraoperative cholangiography showed filling defects within the dilated left. intrahepatic & extrahepatic bile ducts. Postoperative MRI showed residual mass within the left. intrahepatic duct which was hypointense on T1WI and hyperintense on T2WI.
Bile Ducts, Extrahepatic
;
Biliary Tract*
;
Child
;
Child, Preschool
;
Cholangiography
;
Humans
;
Magnetic Resonance Imaging
;
Rhabdomyosarcoma
;
Rhabdomyosarcoma, Embryonal*
;
Sarcoma
2.Embryonal Rhabdomyosarcoma of the Biliary Tree: A Case Report.
Ki Nam LEE ; Duck Hwan CHUNG ; Kyung Jin NAM ; Jong Young OH ; Byung Ho PARK ; Jong Chul CHOI
Journal of the Korean Radiological Society 1995;32(4):639-642
Rhabdomyosarcoma are reportedly the most common soft tissue sarcoma occuring in childhood, but the biliary tree is a rare site of origin for this tumor. Recently we experienced a case of embryonal rhabdomyosarcoma of the biliary tree in a 30-month-old child. UItrasonography showed hypoechoic mass filling the dilated left. intrahepatic & extrahepatic bile ducts, and CT showed hypodense mass with heterogeneous enhancement after contrast infusion. Intraoperative cholangiography showed filling defects within the dilated left. intrahepatic & extrahepatic bile ducts. Postoperative MRI showed residual mass within the left. intrahepatic duct which was hypointense on T1WI and hyperintense on T2WI.
Bile Ducts, Extrahepatic
;
Biliary Tract*
;
Child
;
Child, Preschool
;
Cholangiography
;
Humans
;
Magnetic Resonance Imaging
;
Rhabdomyosarcoma
;
Rhabdomyosarcoma, Embryonal*
;
Sarcoma
3.Treatment of OTA'sNeves and Acquired Bilateral Nevus of OTA-like Macule(abnom)with Q-switched Alexandrite Laser.
Byoung Joo YOUN ; In Pyo HONG ; Jong Hwan KIM ; Nam Ho KIM ; Young Ki SHIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):810-815
The nevus of Ota is a benign dermal melanocytic lesion that most commonly occurs unilaterally in areas innervated by the first and second division of the trigeminal nerve. Acquired bilateral nevus of Ota-like macules(ABNOM) are located bilaterally on the forehead, temples, eyelids, cheeks, and/or nose. They usually occur in the fourth or fifth decade of life in women(rarely in men). In contrast to the nevus of Ota, ABNOM have not been observed in the mucous membranes of the oral cavity, nose, or eyes. Traditional treatments were palliative, risky electrocautery, or cryotherapy. These methods resulted in permanent pigmentary changes and/or scarring. Recently utilizing the principle of selective photothermolysis, the Q-switched Alexandrite laser has been reported to be successful in treating benign pigmentary lesions and tattoos. Our study evaluated the treatment of 127 patients with nevus of Ota and ABNOM with the Q-switched Alexandrite laser(755 nm, 100 nsec). Nevi were treated up to 7 times with 7-8 J/cm2 at a minimum of 6 weeks interval. Good therapeutic effects were gained (up to 50% improvement was seen in 89% of patients.) and our patients were very satisfied. No patients had permanent textural change or scarring. Treatment with on Alexandrite laser for nevus of Ota & ABNOM is considered to be a safe and effective method.
Cheek
;
Cicatrix
;
Cryotherapy
;
Electrocoagulation
;
Eyelids
;
Forehead
;
Humans
;
Lasers, Solid-State*
;
Mouth
;
Mucous Membrane
;
Nevus of Ota
;
Nevus*
;
Nose
;
Trigeminal Nerve
5.c-kit and Ligand Expression in the Mouse Hippocampus after Kainate-induced Seizure.
Hye Nam HONG ; Jong Hwan LEE ; Tae Jin JUNG ; Dong Ho KIM
Korean Journal of Anatomy 1997;30(1):87-98
In the present study, we have etamined the role of c-kit and KL ligand in the mouse brain after kainate-induced seizure. To investigate whether c-kit receptor and KL ligand might involved in kainate-induced apoptosis, the expression patterns of c-kit and KL mRNA and localization of immunoreactivity for c-Kit, SCF and Bcl-2 protein were examined by in situ hybridization technique and immunohistochemical method, respectively, in the mouse hippocampus after kainate treatment. This report is the first demonstration for the role of c-kit receptor and KL ligand in the kainate-induced apoptosis. Our conclusion is based on : 1] c-kit and KL mRNA expressions were increased in CA3 region of the hippocampus in 1h after kainate treatment, 2] immunoreactivities for c-Kit protein and SCF were detected higher level in the CA1 and CA3 sectors in 24h after kainate treatment, 3] expression level for Bcl-2 protein was increased in the CA3 region of the hippocampus 24h after kainate treatment. These results suggest that bcl-2 could promote cell survival of injured neurons in CA3 after kainate-induced seizure. And increased translations of c-kit receptor and KL ligand after kainate injection in this area susgest that c-kit receptor and KL ligand could have a role in the kainate-induced apoptosis.
Animals
;
Apoptosis
;
Brain
;
Cell Survival
;
Hippocampus*
;
In Situ Hybridization
;
Kainic Acid
;
Mice*
;
Neurons
;
Proto-Oncogene Proteins c-kit
;
RNA, Messenger
;
Seizures*
;
Translations
6.beta-Amyloid Neurotoxicity on Basal Forebrain Cholinergic Neuron Cultures.
Dong Ho KIM ; Jong Hwan LEE ; Hye Nam HONG ; Jae Young KO
Korean Journal of Anatomy 1997;30(3):225-234
beta-amyloid[Abeta] peptide consisting of 40 of 42 amino acids peptide is the principal constituent of senile plaques in Alzheimer`s disease. Recently, it has been demonstrated that this peptide and its constituent fragments are toxic to neuron. Basal forebrain cholinergic neurons are preferentially damaged early in the course of Alzheimer`s disease, and the degree of cholinergic decrement correlates well with the severity of dementia. Taking into consideration of toxic properties of Abeta and the selective vulnerability of the cholinergic system, possible effects of beta-amyloid on the cultured basal forebrain cholinergic neurons were tested. Our result showed tha Abeta1-40 induced marked neurodegenerative changes including loss of cell body and dystrophic neurites in the basal forebrain neuronal cultures at 20micrometer. Immunocytochemical study showed that Abeta1-40 causes apparent loss of choline acetyltransferase[ChAT] immunoreactivity and acetycholine esterase[AchE] positive neuritic intergrity in large basal forebrain cholinegic neurons. However, the number of ChAT immunoreactive neurons was not significantly decreased as compared to other neurons in mixed culture system. These results suggest that the basal forebrain neurons are not particularly vulnearable to Abeta and that preferential injury to basal forebrain cholinergic neurons in Alzheimer`s disease may be caused by some other medchanism.
Amino Acids
;
Choline
;
Cholinergic Neurons*
;
Dementia
;
Neurites
;
Neurons
;
Plaque, Amyloid
;
Prosencephalon*
7.CORRECTION OF LOW ANTERIOR HAIR LINE WITH LONG PULSED INFRARED ALEXANDRITE LASER.
Byoung Joo YOUN ; In Pyo HONG ; Jong Hwan KIM ; Nam Ho KIM ; Young Ki SHIM
Journal of the Korean Society of Aesthetic Plastic Surgery 1999;5(2):340-347
A various type of hairline and height of forehead is considered as a result of genetic effect. The conventional corrective surgical operation of low hairline in forehead has been too complicated and painful to apply, and also has many disadvantages such as scar, bleeding, risks of anesthesia. Recently four classes of devices are designed to remove hair with intense light beam : Nd-Yag lasers with carbon cream, the Ruby lasers, the Alexandrite lasers, and the polychromic broad band light source of flashlamp technology. The goal of these therapeutic modality is to destroy the melanin pigment selectively in hair follicle without injuring the skin for permanent epilation. We have been used long pulse infrared Alexandrite laser for treat low hair line in 27 patients from Dec. 1997 to Dec. 1998. We experienced 3 cases of temporary hyperpigmentation and 1 case of bulla, and the most of patients were satisfied in 89%. The average lengthening of forehead was 2.2cm (median line) and 2.3cm (paramedian line). We achieved successful result without permanent hyperpigmentation or scarring
Anesthesia
;
Carbon
;
Cicatrix
;
Forehead
;
Hair Follicle
;
Hair Removal
;
Hair*
;
Hemorrhage
;
Humans
;
Hyperpigmentation
;
Lasers, Solid-State*
;
Melanins
;
Skin
8.Multiplane Transesophageal Echocardiographic Findings of Two Cases of Discrete Subvalvular Aortic Stenosis.
Ki Hwan KIM ; Jong Nam PARK ; Tae Joon CHA ; Seung Jae JOO ; Jae Woo LEE ; Sung Rae CHO
Korean Circulation Journal 1996;26(4):913-920
Discrete subvalvular aortic stenosis is a relatively uncommon cause of the left ventricular outflow obstruction, requiring early intervention. Conventional transthoracic echocardiography may fail in some patients due to insufficient imaging quality. In particular, in patients with a discrete fibrous membrane close to the aortic valve without narrowing of the left ventricular outflow tract, the echocardiographic detection of the membrane may be difficult. Transesophageal echocardiography allows a clear visualization of the aortic valve and the left ventricular outflow tract in virtually all patients, it can be performed rapidly with almost no risk, and it may therfore be helpful in establishing the diagnosis of discrete subaortic stenosis, in particular in patients where the conventional transthoracic approach fails. We have experienced two cases of discrete subaortic stenosis. One case of them was combined with hypertrophic obstructive cardiomyopathy in this report we discussed the utility of multiplane transesophageal echocardiography in patients with discrete subvalvular aortic stenosis.
Aortic Stenosis, Subvalvular*
;
Aortic Valve
;
Cardiomyopathy, Hypertrophic
;
Diagnosis
;
Discrete Subaortic Stenosis
;
Early Intervention (Education)
;
Echocardiography*
;
Echocardiography, Transesophageal
;
Humans
;
Membranes
;
Ventricular Outflow Obstruction
9.Cardiovascular Effects of Propofol as an Induction Agent in Kidney Recipients.
Eun Hwan CHOI ; Soon Ho NAM ; Yang Sik SHIN ; Jong Rae KIM
Korean Journal of Anesthesiology 1995;29(2):192-197
A need has been recognized for a safe and effective induction for patients undergoing elective renal transplantations. We have evaluated the effect of propofol (injection rate; 50 mg/min, average dosage; 2.28+/-0.08 mg/kg, n=10) on a cardiovascular stability compared with that of thiopental (injection rate; 100 mg/min, average dosage; 5.22+/-0.18 mg/kg, n=10) as an induction agent. Blood pressure and heart rate as cardiovascular parameters were checked before induction(control), one, two, three minutes after induction, before and after orotracheal spray of lidocaine, and immediately, one and two minutes after endotracheal intubation. The results were as follows: 1) There were no significant cardiovascular changes in the propofol group during the whole induction period. 2) In the thiopental group, diastolic blood pressures checked just after intubation, which were 120.20+/-7.79 mmHg, were significantly higher than those of one or two minutes after induction, which were 86.30+/-4.36, 88.40+/-3.85 mmHg, respectively. The above results suggest that intravenous propofol (2.0~2.5 mg/kg) is a safe and effective induction agent for renal recipients.
Blood Pressure
;
Heart Rate
;
Humans
;
Intubation
;
Intubation, Intratracheal
;
Kidney Transplantation
;
Kidney*
;
Lidocaine
;
Propofol*
;
Thiopental
10.A Case of Kallmann Syndrome Inherited in Autosomal Dominant Mode.
Yoon Sung NAM ; Sook Hwan LEE ; Woo Sik LEE ; Chan PARK ; Jong Wook KIM ; Kwang Yul CHA
Korean Journal of Fertility and Sterility 1999;26(3):491-495
OBJECTIVE: To report the pedigree of Kallmann syndrome inherited in autosomal dominant mode with variable expressivity. MATERIAL AND METHOD: Case report. RESULTS: The patient had amenorrhea and anosmia but did not have a sign of absolute hypogonadotropic hypogonadism. Her father had an anosmia and her two elderly sisters also had an anosmia but delivered babies uneventfully. Her two male siblings did not show any signs of hypogonadotropic hypogonadism. CONCLUSION: Kallmann syndrome has many different modes of inheritance such as autosomal dominant, autosomal recessive, and X-linked form. So the careful investigation of family pedigree is required.
Aged
;
Amenorrhea
;
Fathers
;
Female
;
Humans
;
Hypogonadism
;
Kallmann Syndrome*
;
Male
;
Olfaction Disorders
;
Pedigree
;
Siblings
;
Wills