1.Adverse factors of hepatic dysfunction during chemotherapy for childhood malignancy.
Dong Hoon KOH ; Hyung Jong LIM ; Young Kwon CHOI ; Hoon KOOK ; Tae Joo HWANG
Journal of the Korean Cancer Association 1993;25(3):417-422
No abstract available.
Drug Therapy*
2.The Clinical Experiences of Ultrasound-Assisted Lipo plasty.
Sang Hoon HAN ; Soo Chul KIM ; Han Koo KIM ; Sang Hoon PARK ; Kyung Suck KOH ; Taik Jong LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2000;27(1):7-13
Suction-assisted lipoplasty is now flrequently-performed pre cedure in plastic surgery, but it has several drawback including bleeding contour irregularity due to its traumatic nature. The recently introduced ultrasound-assisted lipoplasty (UAL) technique uses ultrasonic energy which has specificity in lower density tissue like fat tissue. Therefore, UAL can minimize these compli cations. We performed UAL in 21 patients from OCt. 1988 to Jun 1999. There were 17 females and 4 males, and patient age ranged from 18 to 52 years(average 40 years). A total of 58 areas were operated on for an averge of 28 areas per patient. We used a fivestage technique consisting of tumescent infiltration, ultrasonund treatment, emulsion suction, endermology, and postperative pressuregarment application. Total volume (fluid and fat) removed ranged from 200 to 4,050 cc(averge 1,750 cc) per patient and the lipocrit within the aspirate was 4-8%, which was significantly lower compared with traditional liposuction Residual emulsion was evacuated by endermology and pressuregarment was applied to all patients for postoperative 2-3 months. Pestoperative complications were seroma, induration, and paresthesia, but all these problems resolved spontaneously within a month. One patient required secondary UAL for correction of excess fat at the medial knee. We believe that UAL is a safe and excellent technology in liposuction because of reduced surgical bleeding and good contral of body contour.
Bezafibrate
;
Cations
;
Female
;
Hemorrhage
;
Humans
;
Knee
;
Lipectomy
;
Male
;
Paresthesia
;
Sensitivity and Specificity
;
Seroma
;
Suction
;
Surgery, Plastic
;
Ultrasonics
3.A Less Invasive Approach for Ruptured Aneurysm with Intracranial Hematoma: Coil Embolization Followed by Clot Evacuation.
Je Hoon JEONG ; Jun Seok KOH ; Eui Jong KIM
Korean Journal of Radiology 2007;8(1):2-8
OBJECTIVE: The presence of an intracerebral hematoma from a ruptured aneurysm is a negative predictive factor and it is associated with high morbidity and mortality rates even though clot evacuation followed by the neck clipping is performed. Endovascular coil embolization is a useful alternative procedure to reduce the surgical morbidity and mortality rates. We report here on our experiences with the alternative option of endovascular coil placement followed by craniotomy for clot evacuation. MATERIALS AND METHODS: Among 312 patients who were admitted with intracerebral subarachnoid hemorrhage during the recent three years, 119 cases were treated via the endovascular approach. Nine cases were suspected to show aneurysmal intracerebral hemorrhage (ICH) on CT scan and they underwent emergency cerebral angiograms. We performed immediate coil embolization at the same session of angiographic examination, and this was followed by clot evacuation. RESULTS: Seven cases showed to have ruptured middle cerebral artery (MCA) aneurysms and two cases had internal carotid artery aneurysms. The clinical status on admission was Hunt-Hess grade (HHG) IV in seven patients and HHG III in two. Surgical evacuation of the clot was done immediately after the endovascular coil placement. The treatment results were a Glasgow Outcome Scale score of good recovery and moderate disability in six patients (66.7%). No mortality was recorded and no procedural morbidity was incurred by both the endovascular and direct craniotomy procedures. CONCLUSION: The results indicate that the coil embolization followed by clot evacuation for the patients with aneurysmal ICH may be a less invasive and quite a valuable alternative treatment for this patient group, and this warrants further investigation.
Treatment Outcome
;
Tomography, X-Ray Computed
;
Retrospective Studies
;
Middle Aged
;
Male
;
Intracranial Aneurysm/radiography/*therapy
;
Humans
;
Hematoma/radiography/*therapy
;
Female
;
Embolization, Therapeutic/*methods
;
Drainage/*methods
;
Cerebral Angiography
;
Aneurysm, Ruptured/radiography/*therapy
;
Adult
4.A Primary Extragonadal Teratoma of the Proximal Humerus.
Jae Soo KOH ; Jong Hoon PARK ; Chang Ho KANG
Journal of Korean Medical Science 2009;24(5):989-991
A extragonadal malignant teratoma of the extremity is a rare pheonemenon. We describe a extremely rare case of malignant teratoma of the left proximal humerus in a 14-yr-old female. Radiologic evaluations, including magnetic resonance imaging, suggested a malignant bone tumor, but a pathological examination revealed an immature bony teratoma. Bone scintigraphy and positron emission tomography computed tomography scan showed increased uptake of proximal humerus but no other abnormal lesion.
Adolescent
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Bone Neoplasms/*diagnosis/pathology/radiography
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Female
;
Humans
;
*Humerus/radiography
;
Magnetic Resonance Imaging
;
Positron-Emission Tomography
;
Teratoma/*diagnosis/pathology/radiography
;
Tomography, X-Ray Computed
5.A Study on the Relationship between Sleep Duration and Suicidal Idea in an Urban Area of South Korea.
Yu Jin LEE ; Seog Ju KIM ; In Hee CHO ; Jong Hoon KIM ; Seung Min BAE ; Seung Hee KOH ; Seong Jin CHO
Sleep Medicine and Psychophysiology 2009;16(2):85-90
INTRODUCTION: There has been an increasing interest in the relationship between sleep and suicidality. In addition, suicidal patients habitually report their sleep problems. Although sleep-related complaints and electroencephalographic changes are generally encountered in psychiatric disorders, sleep complaints such as insomnia, hypersomnia and nightmares are more common in suicidal patients. In current study, we aimed at investigating the relationship between self-reported sleep duration and suicidality in general population. METHODS: One thousand general population (male : female=500 : 500, mean age=39.6+/-11.6 years, ranged age=20-77 years) completed Center for Epidemiologic Study-Depression (CES-D), Beck Suicide Intent scale (BSI), Spielberger State-Trait Anger Expression Inventory (STAXI), Barratt Impulsiveness Scale (BIS), Morningness-Eveningness Scale (MES) and brief questionnaire of sleep habits. RESULTS: After controlling for age and sex, score of BSI was correlated positively with the score of CES-D, STAXI and BIS on partial correlation analysis (r(p)=0.251 ; p<0.001, r(p)=0.352 ; p<0.001, and r(p)=0.175 ; p<0.001, respectively). In addition, score of BSI was inversely correlated with the score of MES (r(p)=-0.066; p=0.037). However, score of BSI showed no significant correlation with sleep duration. However, regression analysis revealed that short (<6 hrs) or long (>10 hrs) sleep duration, the family history of psychiatric illness, the score of CES-D, and the score of STAXI predicted higher score of BSI significantly in total subjects (F=17.837, adjusted R2 =0.166 ; p=0.003, p=0.003, p<0.001, and p=0.003, respectively). This model was explained better in depressed subjects with 16 or higher score of CES-D (F=9.920, adjusted R2=0.298). CONCLUSION: Current result suggested that not only short sleep duration (<6 hrs) but also long sleep duration (>10 hrs) might be related to suicidality.
Anger
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Depression
;
Disorders of Excessive Somnolence
;
Dreams
;
Humans
;
Surveys and Questionnaires
;
Republic of Korea
;
Sleep Initiation and Maintenance Disorders
;
Suicide
6.Phasic Coronary Artery Flow Profiles in Patients with Aortic Valve Disease.
Jong Hoon KOH ; Han Soo KIM ; Seung Jea TAHK ; Dong Jin KIM ; Joon Han SHIN ; Byung Il CHOI
Korean Circulation Journal 1998;28(10):1691-1699
BACKGROUND: The previous reports have demonstrated that coronary artery flow profiles might change in patients with aortic valve disease. Our objective was to assess phasic coronary artery flow and velocity characteristics and coronary flow reserve in patients with severe aortic vale disease. METHOD: We studied six patients (4 men and 2 women, mean age 61.3+/-6.3 years) with aortic regurgitation and seven patients (3 men and 4 women, mean age 66.3+/-10.3 years) with aortic stenosis. Coronary flow velocity was measured at the proximal portion of left anterior descending artery with 0.014-inch Doppler tipped guide wire and intracoronary injection of adenosine. Nineteen patients (11 men and 8 women, mean age 52+/-9.8 years) with normal coronary artery were served as normal control. Result: The velocity-time integral of systolic coronary flow (SPVi) was significantly higher in patient with severe aortic regurgitation than control (21.1+/-5 vs 9.4+/-3.1, p<0.05, respectively) and ratio of diastlic to systolic the velocity-time integrals (DSiR) was significantly lower in patient with severe aortic regurgitation than control subject (1.5+/-0.5 vs 3.7+/- 0.8 p<0.05, respectively). Patients with severe aortic stenosis had significantly higher velocity-time integral of diastolic coronary flow (DPVi) than control subject (17+/-9.7 vs 8.8+/-3.0 p<0.05, respectively) and slighly higher DSiR than control subject (4.0+/- 2.5 vs 3.7+/-0.8 p<0.05, respectively). Coronary flow reserve was significantly decreased in patient with aortic valve disease compared with control subject (2.1+/-0.8 vs 3.2+/-0.4 p<0.05, respectively). CONCLUSION: Coronary flow reserve decreased significantly in patients with AR and with AS compared with normal control. Coronary blood flow profiles in patients with AR was characterized by systolic flow predominance and reduced diastolic flow whereas patients with AS was a tendency toward decreased systolic flow and increased diastolic flow.
Adenosine
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Aortic Valve Insufficiency
;
Aortic Valve Stenosis
;
Aortic Valve*
;
Arteries
;
Coronary Vessels*
;
Female
;
Humans
;
Male
7.Rotating Shift and Daytime Fixed Work Schedules as a Risk Factor for Depression in Korean Police Officers.
Seung Min BAE ; Yu Jin LEE ; Seog Ju KIM ; In Hee CHO ; Jong Hoon KIM ; Seung Hee KOH ; Seong Jin CHO
Sleep Medicine and Psychophysiology 2010;17(1):28-33
OBJECTIVES: Working at other times than the regular day shift has been reported to be a stressor associated with health consequences and mental disorders as well as disturbance of sleep. In current study, we aimed at investigating the relationship between work schedule, sleep quality and depression among police officers. METHODS: Eleven hundreds and forty five police officers (male:1040, female:105) completed questionnaires of basic socio-demographic data, Pittsburgh Sleep Quality Index (PSQI), Korean Scale of Occupational Stress (KOSS), Impact of Event Scale - Revised (IES-R) and Center for Epidemiologic Study-Depression (CES-D). RESULTS: After controlling for age, sex and educational level, score of CES-D was correlated positively with the score of KOSS, PSQI and IES-R on partial correlation analysis (r=-0.077;p=0.009, r=0.262;p<0.000 and r=0.421, p<0.000, respectively). Logistic regression analysis revealed that female sex, age, the score of KOSS and IES-R and schedule of rotating shift work predicted higher score than 16 score of CES-D significantly in total subjects (p=0.023, p=0.015, p=0.000, p=0.000 and p=0.022, respectively). CONCLUSION: Current result suggested that not only female sex, age, higher occupational stress and impact of event scale but also rotating shift work schedule might be related to depression among police officers.
Appointments and Schedules
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Depression
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Female
;
Humans
;
Logistic Models
;
Mental Disorders
;
Police
;
Surveys and Questionnaires
;
Risk Factors
8.Surgical Fepair of Achilles Tendon Ruptures: modified lindholm method.
Chung Nam KANG ; Jong Ho KIM ; Dong Wook KIM ; Young Do KOH ; Sang Hoon GO ; Seong Man KIM
The Journal of the Korean Orthopaedic Association 1997;32(3):711-718
Treatment of Rupture of Achilles tendon was first reported by Pare, 1575 and thereafter the various causes, diagnostic & therapeutic method of the ruptured tendon have been described by many authors. The two options of treatment are conservative management and surgical treatment and currently surgical intervention has been more popular. There are various surgical techniques which have been reported by many surgeons to treat the acute rupture of the Achilles tendon. In this report, 18 cases ( 11 male & 7 female ) of injuried Achilles tendon had been treated by the modified Lindholm method and follow-up study of 18 cases had been made during 28 months from august. 1993 to december, 1995. The results as follows; 1. After repair by the modified Lindholm method, a long leg cast was applied, and then aweight bearing was started average 8 weeks postoperatively. It can be demonstrated to shorten hospitalization and early ambulation compared to other surgical techniques 2. Postoperative power of triceps surae muscle was improved to normal in 15 patients ofthe 18 patients, and muscle power was good in 3 patients, but, all cases was improved to nearly normal whithin the last follow up. 3. Heel to floor distance was 0.6cm less on the operated side than on the normal side, and the difference decreased to 0.2cm at the last follow up. 4. The calf atrophy was minimal, and active range of motion of ankle was within normal limit. 5. We suggest that the procedure is recommended for one of the methods of the treatment of acute rupture of the Achilles tendon, because it is easy to do and permits early weight bearing and the complication is less.
Achilles Tendon*
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Ankle
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Atrophy
;
Early Ambulation
;
Female
;
Follow-Up Studies
;
Heel
;
Hospitalization
;
Humans
;
Leg
;
Male
;
Range of Motion, Articular
;
Rupture*
;
Tendons
;
Weight-Bearing
9.Analysis of Prognostic Factors in Surgical Treatment for Lumbar Disc Herniation.
Chung Nam KANG ; Jong Ho KIM ; Dong Wook KIM ; Young Do KOH ; Sang Hoon GO ; Cheon Bang HAN
The Journal of the Korean Orthopaedic Association 1997;32(4):1090-1097
It is important to follow strict indications for surgery and recognize prognostic factors in order to get good results in the surgical treatment of herniated nucleus pulposus. 55 patients with herniated nucleus pulposus were studied who had had laminectomy and discectomy and were followed up for more than 1 year in order to analyze the correlation between various factors including history, physical examination and radiologic finding and surgical results. Age, sex, symptom duration, location of the herniation, smoking, occupation, physical examination, disc height change, MRI findings, operation time and bleeding volume were evaluated as prognostic factors that seemed to influence surgical result. The results are as follow 1. Female had significantly better surgical results than male (P<0.05). 2. Non-smokers had significantly better surgical result than smokers (P<0.01). 3. In MRI finding, protruded disc had significantly better surgical result when it had involved spinal canal posterolaterally than centrally (P<0.01). 4. The less bleeding volume, the better surgical result (P<0.05).
Diskectomy
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Female
;
Hemorrhage
;
Humans
;
Laminectomy
;
Magnetic Resonance Imaging
;
Male
;
Occupations
;
Physical Examination
;
Smoke
;
Smoking
;
Spinal Canal
10.Index of Microcirculatory Resistance as Predictor for Microvascular Functional Recovery in Patients with Anterior Myocardial Infarction.
Seung Hoon YOO ; Tae Kyung YOO ; Hong Seok LIM ; Mi Young KIM ; Jong Hoon KOH
Journal of Korean Medical Science 2012;27(9):1044-1050
IMR is useful for assessing the microvascular dysfunction after primary percutaneous coronary intervention (PCI). It remains unknown whether index of microcirculatory resistance (IMR) reflects the functional outcome in patients with anterior myocardial infarction (AMI) with or without microvascular obstruction (MO).This study was performed to evaluate the clinical value of the IMR for assessing myocardial injury and predicting microvascular functional recovery in patients with AMI undergoing primary PCI. We enrolled 34 patients with first anterior AMI. After successful primary PCI, the mean distal coronary artery pressure (Pa), coronary wedge pressure (Pcw), mean aortic pressure (Pa), mean transit time (Tmn), and IMR (Pd * hyperemic Tmn) were measured. The presence and extent of MO were measured using cardiac magnetic resonance image (MRI). All patients underwent follow-up echocardiography after 6 months. We divided the patients into two groups according to the existence of MO (present; n = 16, absent; n = 18) on MRI. The extent of MO correlated with IMR (r = 0.754; P < 0.001), Pcw (r = 0.404; P = 0.031), and Pcw/Pd of infarct-related arteries (r = 0.502; P = 0.016). The IMR was significantly correlated with the DeltaRegional wall motion score index (r = -0.61, P < 0.01) and DeltaLeft ventricular ejection fraction (r = -0.52, P < 0.01), implying a higher IMR is associated with worse functional improvement. Therefore, Intracoronary wedge pressures and IMR, as parameters for specific and quantitative assessment of coronary microvascular dysfunction, are reliable on-site predictors of short-term myocardial viability and Left ventricle functional recovery in patients undergoing primary PCI for AMI.
Adult
;
Aged
;
Aged, 80 and over
;
Anterior Wall Myocardial Infarction/*physiopathology
;
Arterial Pressure/physiology
;
Coronary Occlusion/pathology
;
Echocardiography
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Microcirculation/*physiology
;
Middle Aged
;
Percutaneous Coronary Intervention
;
*Predictive Value of Tests
;
Prospective Studies
;
Recovery of Function
;
Risk Factors