1.Unified Dietary Guideline.
Journal of the Korean Medical Association 1999;42(11):1089-1095
No abstract available.
Nutrition Policy*
4.Hypoglossal-facial nerve anastomosis for reinnervation of the paralysed face.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):136-143
No abstract available.
5.Hypoglossal-facial nerve anastomosis for reinnervation of the paralysed face.
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):136-143
No abstract available.
6.Prediction of Labor in Term Pregnancy Ising Fetal Fibronectin and Transvaginal Ultrasonography.
Korean Journal of Perinatology 1999;10(1):17-23
OBJECTIVE: We performed the transvaginal ultrasonographic evaluation of uterine cervix and fetal fibronectin in cervicovaginal secretions in women after 37 complete weeks of gestation to predict the onset of labor. METHODS: Total 80 primiparous or multiparous women were divided into two groups on the duration between evaluation and onset of labor. The biometric analysis of uterine cervix(cervical index, endocervical length, funneling, funnel length and width) was done by transvaginal ultrasonography. The cervicovaginal fetal fibronectin was measured by fetal fibronectin immunoassay (ELISA kit, Adeza Biochemical, USA). The efficacy of these method was analyzed with Pearson chi-square test, receiver-operator characteristic curves, and multiple logistic regression test. RESULTS: 1) There were no significant differences in clinical characteristics between two groups. 2) Group 1(onset of labor within 7 days after evaluation) showed significantly shorter endocervical length(Group 1: 2.33+/-0.75cm,Group 2: 2.93+/- 0.42cm, p=0.013), higher value of cervical index(Group 1: 1.27+/-0.67, Group 2: 0.62+/-0.34, p=0.008) and higher level of fetal fibronectin(Group 1: 98.65+/-11.34ng/ml, Group 2: 13.37+/- 2.7ng/ml, p=0.004). 3) The ROC curve analysis showed that a level of endocervical length <2.64mm, cervical index> 0.7, fetal fibronectin> 60ng/ml had the diagnostic performance in predicting group 1. Fetal fibronectin level in cervicovaginal secretion> 60ng/ml showed the highest diagnostic index in predicting the onset of labor within 7 days(p<0,001, odds ratio=21.3). CONCLUSION: Cervicovaginal fetal fibronectin predicts delivery within 7 days more accurately than cervical index, endocervical length. Combine use of these tests improve the diagnostic efficiency and allowed prediction of onset of labor, identifying a subgroup of patients who may require aggressive treatment.
Cervix Uteri
;
Chi-Square Distribution
;
Female
;
Fibronectins*
;
Humans
;
Immunoassay
;
Logistic Models
;
Pregnancy*
;
ROC Curve
;
Ultrasonography*
7.Comparison of between Live and Dead Fetuses: Efficacy of Intravaginal Misoprostol in Termination of Second Trimester Pregnancy.
Korean Journal of Obstetrics and Gynecology 1999;42(3):464-467
OBJECTIVE: To compare the efficiency, success rate and abortion time between the live and the dead fetus in second trimester pregnancy termination with intravag-inal misoprostol. SUBJECTS AND METHODS: A total of 45 pregnant women between 18-29 weeks of gestation with medical, obstetric, or genetic reasons for termination were recruited to receive 50 ug misoprostol inserted intravaginally (posterior fornix) every 4 hours. RESULTS: The success rate of complete termination(abortion) within 12 and 24 hours in dead fetuses were 78.2% and 95.6%, respectively, while in live fetuses were 36.3% and 90.9%, respectively. The mean abortion time of the dead fetus group (10.31+/-3.43 hours) was significantly less than that of the live fetus group (14.20+/-3.31 hours). No serious complications occurred in terms of hemorrhage, diarrhea, nausea and vomiting. CONELUSION: Intracervicovaginal misoprostol is a safe and effective method for second trimester pregnancy termination. The abortion time is less in dead fetus pregnancy than that in the live fetus pregnancy.We used 50 ug tablets of misoprastol every four hours. But, we suspect that the regimen of 100ug misoprostol inserted intracervicovaginally every eight hours will beis the proper and optimal method for pregnancy termination.
Diarrhea
;
Female
;
Fetus*
;
Hemorrhage
;
Humans
;
Misoprostol*
;
Nausea
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnant Women
;
Tablets
;
Vomiting
8.A Study of the Relationship between p53 Mutation and Proliferating Activities in Astrocytic Tumors.
Korean Journal of Pathology 1999;33(3):158-168
To evaluate the relationship between p53 protein expression and proliferating activity in astrocytic tumors, we performed a study using 37 cases of astrocytic tumors; 13 cases of low-grade astrocytoma (LGA), 9 cases of anaplastic astrocytoma (ANA), and 15 cases of glioblastoma multiforme (GM). The p53 protein expression was studied by immunohistochemical staining (IHC) with DO-7 monoclonal antibody in 37 cases and p53 mutation was detected by single strand conformational polymorphism (SSCP) using PCR products of 31 cases. Proliferating activities were detected by Ki-67 (MIB-1) and proliferating cell nuclear antigen (PCNA). Immunohistochemically, 24.3% (9/37) of astrocytic neoplasms showed p53 expression, which consisted of 7.7% (1/13) of LGA, 44.4% (4/9) of ANA, and 26.7% (4/15) of GM. The p53 expression was statistically significant between the tumor grades. p53 mutations on exon 5 were noted in 6 (19.4%) out of 31 cases of astrocytic tumors. Average indices of MIB-1 and PCNA were 1.5 2.6% and 7.0 10.1% in LGA, 10.0 12.7% and 23.7 23.2% in ANA, and 30.9 22.4% and 69.9 26.7% in GM, respectively. p53 positive group by IHC showed significantly higher average MIB-1 (26.2 23.5%) and PCNA index (56.7 30.3%) than those (12.1 18.3%, 27.6 29.6%) of p53 negative group (p<0.05). p53 mutation group also showed significantly higher MIB-1 (30.7 26.0%) and PCNA index (55.5 32.6%) than those without p53 mutation (10.8 16.5%, 24.2 28.7% respectively). These results showed that about one-fifth of astrocytic tumors have p53 abnormalities, which were related with higher proliferating activities than those without p53 abnormalities.
Astrocytoma
;
Exons
;
Glioblastoma
;
Immunohistochemistry
;
Polymerase Chain Reaction
;
Proliferating Cell Nuclear Antigen
9.A clinical analysis of tetanus.
Journal of the Korean Surgical Society 1991;40(1):77-87
No abstract available.
Tetanus*
10.The Roles of IgG and Albumin as a Predictor of Frequent Relapse in Nephrotic Syndrome.
Journal of the Korean Pediatric Society 1994;37(9):1245-1250
The etiology of nephrotic syndrome in unknown. The characterization were proteinuria, hypoalbuminemia, generalized edema and hyperlipidemia. To assess the recurrence factors in the nephrotic syncrome, we measured serum immunoglobulin (IgG, IgA, IgM), albumin, complement, cholesterol and the 24-hour total urine protein at the initial relapse of nephrotic syndrome. Each data of frequent and infrequent relapsed nephrotic syndrome were compared. In total 67 cases, 18 cases were frequent relapsers and 26 cases were infrequent relapsers and 23 cases were normal control without renal disease. The levels of IgG and albumin in frequent relapser were 304 mg/dl and 1.59 g/dl as compared with 440 mg/dl and 2.06 g/dl in infrequent relapsers. The levels of IgG and albumin were signifecantly lower in frequent relapser than infrequent relapsers (p<0.05). This study might be useful to predict that very low levels of IgG and albumin at the first relapse might be related to high risk chances of frequent relapse in children with nephorotic syncrome.
Child
;
Cholesterol
;
Complement System Proteins
;
Edema
;
Humans
;
Hyperlipidemias
;
Hypoalbuminemia
;
Immunoglobulin A
;
Immunoglobulin G*
;
Immunoglobulins
;
Nephrotic Syndrome*
;
Proteinuria
;
Recurrence*