The characteristics of craniofacial complex mere different from each individual, based on age, sex, size, race and environmental factors. This study was undertaken to find out the sexual and racial difference of the craniofacial complex using lateral cephalometrics and previous studies. The material of this study was lateral cephalometric radiograms, obtained from 100 Korean adults (50 males and 50 females) ranged 20 to 27 years old, who have normal occlusion and pleasing profile. The results obtained from this study there as follows : 1. The mean values in the craniofacial complex of some Korean adults pith normal occlusion mere established. 2. The maxillae of female subjects there more protrusive than those of males. 3. In size the craniofacial complex, the male subjects were greater than females. 4. In position of upper and lower incisors, the male subjects there more protrusive than females. 5. In ratios between anterior and posterior facial height, the male subjects mere higher than females. 6. The upper incisors of some Korean adults mere relatively more protrusive than those of the other ethnic groups.
Adult* ; Continental Population Groups ; Ethnic Groups ; Female ; Humans ; Incisor ; Male ; Maxilla

A clinical study of traumatic amputation by railroad accidents was made an 124 patients with 154 amputee, who had been treated at Department of Orthopaedic Surgery, National Seoul Hospital, during the 4 years period from January 1976 to December 1979. The results of this study are as follows: 1. The ratio of male to female was 9 to 1. The 3rd decade of age group showed the hightest number of accident causalties, as much as 37.1%. 2. Causalties showes a maximum during the sprlng (37.1%) and a minimum during winter. 3. The most common injured sites of the amputee were B–K in 44 cases among 154 cases of the amputee. 4. Considering the number of the multiple amputee in 26 casee among 124 cases, frequently they developed in 2 sites with 22 cases, 3 sites with 4 cases. 5. The frequent fracture sites with combined amputation were 18 cases of the pelvic bone, 12 cases of femur in amputation of the lower extremity. 6. Our methods of treatment were debridement, debridement and primary skin closure, debridement with open amputation, circular amputation, closed amputation with skin graft, and closed amputation. 7. The major complications were phantom limb in 108 cases (70.1%), infection in 44 cases (28.6%). 8. The most frequent infectious agent was pseudomonas (16 cases).
Amputation ; Amputation, Traumatic ; Amputees ; Clinical Study ; Debridement ; Female ; Femur ; Humans ; Lower Extremity ; Male ; Pelvic Bones ; Phantom Limb ; Pseudomonas ; Railroads ; Seoul ; Skin ; Transplants

No Abstract Available.

Inflammatory linear verrucous epidermal nevus(ILVEN) is a rare variant of epidermal nevus characterized by an early age of onset, an unilateral pruritic inflammatory psoriasiform lesion, and relative refractoriness to treatment. It has been reported that ILVEN mainly occur in the lower extremities but develop in the upper extremities, neck and trunk. Herein, we present a case of ILVEN occurring in the left temporal scalp of a 32-year-old woman which, in our review of literature, has not been reported as a development site.
Adult ; Age of Onset ; Female ; Humans ; Lower Extremity ; Neck ; Nevus ; Nevus, Sebaceous of Jadassohn* ; Scalp* ; Upper Extremity

The purpose of this study was to investigate kinetics of the osteblast cell lineage in the periosteum and endosteum according to different distraction rates in callotasis of rats' Tibiae. 120 rats underwent osteotomy at the proximal metaphysio-diaphyseal junction of the left tibia for callotasis. Lengthening was started with varying distraction rates of 0.25 mm (group I), 0.5 mm (group II), 0.75 mm (group III), 1.0 mm (group IV) until 3.5 mm length gain was achieved. The animals that had osteotomy alone without lengthening served as a control(group V). Immunohistochemical staining of proliferating cell nuclear antigen(PCNA), osteocalcin and transglutaminase C(TGase C) were done on the four animals on each group sacrified at post-distraction 1, 3, 5, 7, 14, 28 days in order to observe the temporal changes among the experimental and control groups. At each examination, radiographic and histological studies were also done in order to correlate the immunohistochemical findings. The results obtained are summarized as follow; 1. The staining rate of PCNA was highest at the early distraction(day 1) phase and subsequently decreased in all groups. The staining rate of the cells in the periosteum was significantly higher than that of the cells in the endosteum (p < 0.01). 2. The expression rates of osteocalcin in the periosteum of all groups were significantly higer than those in the endosteum (p < 0.01). 3. The expression rates of TGase C in the periosteum of all groups were significantly higer than those in the endosteum (p < 0.05). 4. Radiological and histological studies revealed that successful regenerate bone healing was achieved in groups, I, II and III but not complete in group IV. In conclusion, immunohistochemical study on callotasis of rats' tibiae revealed that the osteoblast cell lineage in the periosteum is more activated than that in the endosteum for proliferation and differentiation by distraction, suggesting that the periosteum plays a more important role in neo-osteo-genesis in the distraction gap. Daily distraction rate range of 0.25 mm to 0.75 mm in two increments is the appropriate for successful distraction osteogenisis of rat's tibia, but the rate of 0.25 mm a day is significantly better than that of 0.75 mm upon immunohistochemical observation.
Animals ; Cell Lineage ; Kinetics ; Osteoblasts ; Osteocalcin ; Osteogenesis, Distraction ; Osteotomy ; Periosteum ; Proliferating Cell Nuclear Antigen ; Rats ; Tibia

A 55 year old male complain right shoulder pain and right upper quadrant pain about three months. He was a heavy alcoholism. Highly selective angiography, CT scan and operation findings suggest primary malignant neoplasm of the liver. Right hepatic lobectomy and partial diaphragmectomy was done under impression of heaptocellular carcinoma. The specimen measured 15x11x9 cm and disclose relatively hard and nodular mass devoid of cirrhotic changes. Cut surface show unilobar large mass measuring 11x8x6 cm and bearing brightly yellow discoloration and multifocal hemorrhagic necrosis. Histological characteristics were diffuse proliferation of large neoplastic cells with ample cytoplasm, containing granular materials, erythrophagocytosis, neutrophagocytosis and hemosiderin pigments. Atypical and bizarre mitosis and multinucleated giant cells bearing abundant erythro and neutrophagocytosis were frequently seen. The large or vesicular nuclei were irregular, with occasional deep indentations and revealed sharply defined nuclear membrane, coarse chromatin and conspicious nucleoli. Ultrastructurally the cytoplasm of neoplasltic cells had lysosomal granule, phagolysosome, phagocytized material and residual bodies. Immunohistochemical stains for alpha 1-antitrypsin, alpha 1-antichymotrypsin, vimentin and lysozyme showed positive reactions, but, alpha fetoprotein, cytokeratin, S-100 protein, factor VIII, complement 3 receptor and carcinoembryonic antigen were negative. Alpha-naphtyl acetate esterase activity in paraffin embedded tissue ribbon showed negative reaction. These findings show compatible with primary malignant lymphoma, true histiocytic type, (histiocytic sarcoma, Kupffer cell carcinoma) of the liver.
Male ; Humans

No abstract available.
Humans

No abstract available.
Humans*

The effect of a secretory proteinase from the pathogenic amoebae Acanthamoeba castellanii on hosts defense-oriented or regulatory proteins such as immunoglobulins, interleukin-1, and protease inhibitors was investigated. The enzyme was found to degrade secretory immunoglobulin A (sIgA), IgG, and IgM. It also degraded interleukin-1alpha (IL-1alpha) and IL-1beta. Its activity was not inhibited by endogenous protease inhibitors, such as alpha2-macroglobulin, alpha1-trypsin inhibitor, and alpha2-antiplasmin. Furthermore, the enzyme rapidly degraded those endogenous protease inhibitors as well. The degradation of hosts defense-oriented or regulatory proteins by the Acanthamoeba proteinase suggested that the enzyme might be an important virulence factor in the pathogenesis of Acanthamoeba infection.
Acanthamoeba/*enzymology/pathogenicity ; Animals ; Endopeptidases/*physiology ; Immunoglobulins/*metabolism ; Interleukin-1/*metabolism ; Protease Inhibitors/*metabolism ; Support, Non-U.S. Gov't ; Virulence

Smooth muscle cell, the main contractile-relaxing component of the corpora cavernosa, undergoes degenerative changes when the blood supply of the corpora cavernosa is disturbed and results in erectile dysfunction. Recently, the main cause of venogenic erectile dysfunction has also been reported to be a corporal veno-occulsive dysfunction that develops following the disturbance of physiologic relaxation of the smooth muscle cell of the corpora cavernosa by degenerative and fibrotic change. The outcome of corrective vascular surgeries for both the arteriogenic and venogenic impotence is not so promising so far. The ultrastructural changes of the corporeal smooth muscle cells in 21 arteriogenic, 3 venogenic and 11 diabetogenic impotent men together with 8 psychogenic impotent patients as a control group were compared each other to investigate the pathogenesis of the erectile dysfunction on morphologic basis and validity of the corrective vascular surgery for the vasculogenic impotence. The results were as follows 1. In the psychogenic impotence, the smooth muscle cells showed well preserved contractile filament and dense body. either evenly distributed or conglomated glycogen without thickening of the basal lamina. 2. In the arteriogenic impotence, nearly half of the cases we examined smooth muscle cells showed degenerative changes with thickening of the basal lamina in part, and showed a paucity or the dense bodies and contractile filaments, decreased glycogen comparing to the smooth muscle cells of the psychogenic impotence. 3. In the venogenic impotence, the smooth muscle cells showed marked atrophy and disorganization in addition the thickening of basal lamina. 4. Also in the diabetogenic impotence, the smooth muscle cells showed similar changes to those of the arteriogenic impotence and particularly the basal lamina was more remarkably thickened. It is concluded that the degenerative and fibrotic changes could be a primary. or secondary cause of the venogenic, arteriogenic and diabetogenic impotence, and therefore biopsy of the corpora may be considered to select proper patients before the corrective vascular surgeries and to enhance their success rates.
Atrophy ; Basement Membrane ; Biopsy ; Erectile Dysfunction* ; Female ; Glycogen ; Humans ; Impotence, Vasculogenic ; Male ; Muscle, Smooth* ; Myocytes, Smooth Muscle* ; Relaxation