Mullerian Mucinous papillary Cyatadenernas of Borderline tumor(MMBT) is lined by mucinous epithelium of endocervical type and is characterized by papillae architecturally similer to those of serous horderline tumors, It has been described rarely in the literature, Thia case was reported with a brief review of the concerened literatures. It has important clinical and pathological diBerences from mucinous birderline tumors with intestinal differentiation, but has many similatities to mixed epithelial borderline tumora of Mulierian type. Recently, a case of MMBT in a 22 years old woman was experienced at our department. We presented this case with a brief review of literature.
Cystadenoma, Papillary* ; Epithelium ; Female ; Humans ; Mucins* ; Young Adult

BACKGROUND: Oculocutaneous albinism (OCA) is a genetic disorder of the melanin pigment system in which melanin synthesis is reduced or absent in the skin, hair, and eyes. OCA is classified into two major types, and tyrosinase-related OCA can be produced by mutations of the structural gene for tyrosinase enzyme (TYR gene). OBJECTIVE: The purpose of this study was to analyze the segregation of mutant alleles of the TYR gene in tyrosinase-negative and tyrosinase-positive Korean OCA patients and families. METHODS: We amplified exon I, II, and III of the TYR gene of Korean OCA patients and their families by polymerase chain reactions (PCR), and analyzed the mutations by restriction fragment length polymorphism (RFLP) analysis in exon I and single-strand conformation polymorphism (SSCP) analyses in exon II and exon III. RESULTS: Two tyrosinase-negative cases showed mutations in exon I. Four tyrosinase-nega-tive cases and one tyrosinase-positive case showed mutations in exon II, and one tyrosinase-neg- ative case showed mutations in exon III. In summary, we found three kinds of mutation in four tyrosinase-negative OCA patients and one tyrsinase-positive OCA patient. CONCLUSIONS: RFLP and SSCP analysis can provide a basis for a rapid and sensitive screening system to detect TYR gene mutations of Korean OCA patients and their families.
Albinism, Oculocutaneous* ; Alleles ; Exons ; Hair ; Humans ; Korea* ; Mass Screening ; Melanins ; Monophenol Monooxygenase ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Polymorphism, Single-Stranded Conformational ; Skin

No abstract available.
Humans

No abstract available.
Uterus*

BACKGROUND: Defective adhesion and migration of melanocyte may be involved in pathogenesis of vitiligo. Tenascin, a glycoprotein of the extracellular matrix, has a role in cell adhesion and migration. It has been reported that abundant expression of tenascin in vitiligo lesion may inhibit melanocyte adhesion and migration. OBJECTIVE: To investigate the tenascin expression in vitiligo skin lesions and to compare with clinical findings. METHODS: We studied 9 patients with vitiligo. The expressions of tenascin were studied by immunahistochemieal techniques.
Cell Adhesion ; Extracellular Matrix ; Glycoproteins ; Humans ; Melanocytes ; Skin ; Tenascin* ; Vitiligo*

BACKGROUND: Atopic dermatitis, characterized by dry, flasky, easily irritated skin, is the most common form of dermatitis seen during childhood. Infants with atopic dermatitis and other eczematous conditions need special dermatologic care to hydrate their skin and to minimize contact with irritants or allergens. OBJECTIVE: The purpose of our study is to evaluate the safety and efficacy of the skin products developed for children. METHODS: Twenty-eight normal children and 26 children with atopic dermatitis were evaluated clinically after using following commercal skin products : (lotion, cream, shampoo, soap, face wash wash) for 2 weeks. Water content of the skin of 14 volunteers was measured serialy over 8 haurs at 2 hour intervals after the application of each skin product. The skin pH of 16 volunteers was also measured serialy over 60 minutes at 30 minute intervals after application. We performed visual skin erythema grading, skin erythema grading by dermaspectrometer, transepidermal water loss measurement, skin water content measurement, and keratinocyte morphology observation by D-squame after the application of the skin products to 13 volunteers for 4 days.
Allergens ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Child ; Dermatitis ; Dermatitis, Atopic ; Erythema ; Humans ; Hydrogen-Ion Concentration ; Infant ; Irritants ; Keratinocytes ; Keratosis, Seborrheic ; Skin* ; Soaps ; Volunteers

We present the case of a 7 year-old child who underwent angioplasty with a stent for anastomosis site stenosis between a left subclavian artery free graft and the left main coronary artery in an arterial switch operation.
Angioplasty* ; Child* ; Constriction, Pathologic ; Coronary Vessels ; Humans ; Stents* ; Subclavian Artery ; Transplants ; Transposition of Great Vessels

No abstract available.
Candidiasis* ; Fluconazole* ; Humans

A clinocostatistical observation was made on 191 cases of inpatients & 42 cases of out-patients, who had beem admitted or controlled but to streptococcal infections & its related diseases at the Department of pediatrics, N.M.C. from Jan. 1971 to Dec. 1977. The results were obtained as follows: 1) The streptococcal infections occupied 3.6% of all the inpatients(5,317) during the period. Among 233 cases, 137 cases(58.8%) were male. The annual incidence was between 1.9% and 4.2%. 2) The related disease entities were acute glomerulonephritis (70.8%), rheumatic fever (18.4%), Henoch-Sh?lein purpura (3.9%), acute tonsillitis (1.7%), scarlet fever (1.3%) and others in order. 3) The peak age incidence was between 7 to 9 year and the seasonal incidence showed prevalance in cold months from October to February. 4) The URI was the most common preceding event both in acrte glomerulonephritis (53.9%) & rheumatic fever (39.5%). 5) The mean interrval between the onset of streptococcal infections and its related diseases of acute glomerulonephritis & rheumatic fever were 6 to 10 days & 11 to 15 days, respectively. 6) The main symptoms of over all streptococcal infections were fever, edema, proteinuria, hematuria & throat injection. 7) Lab. Data showed elevated E.S.R. in 59.7%, leucocytosis in 41.6%, increased ASO titer in 96.6% & positive CRP in 79.4% of the cases. Positive culture from throat swab, CSF or pus were obtained in 18.1% of the cases.
Edema ; Fever ; Glomerulonephritis ; Hematuria ; Humans ; Incidence ; Inpatients ; Male ; Outpatients ; Palatine Tonsil ; Pediatrics ; Pharynx ; Proteinuria ; Purpura ; Rheumatic Fever ; Scarlet Fever ; Seasons ; Streptococcal Infections* ; Suppuration ; Tonsillitis

Surgical approach to the popliteal arterial aneurysm involves medial and posterior approaches. Posterior approach does not need division of hamstring muscle tendons and gastrocnemius head, which is necessary in medial approach for exposure of the entire popliteal artery (PA). Further, it has the advantage of harvesting the lesser saphenous vein without the need of additional incision. Posterior approach to vessels below PA was reported to be effective for bypass from PA to crural vessels in patients with limb ischemia. We report a case of popliteal aneurysm approached posteriorly. A 49-year-old male patient presented with a left popliteal mass and calf claudication for 2 years. Preoperative ultrasonography, MRI and angiography showed a thrombosed popliteal aneurysm. With the patient in left lateral position, the popliteal arterial aneurysm was exposed posteriorly, the lesser saphenous vein was harvested, the crural vessels were exposed by division of gastrocnemius and soleus muscles, and exclusion of the aneurysm and bypass from proximal PA to posterior tibial artery was done. Postoperatively, the patient experienced mild leg edema which soon disappeared, and he was discharged on the 23rd postoperative day. We found the posterior approach to the popliteal and proximal tibial artery to be simple and effective.
Aneurysm* ; Angiography ; Edema ; Extremities ; Head ; Humans ; Ischemia ; Leg ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Muscles ; Popliteal Artery ; Saphenous Vein ; Tendons ; Tibial Arteries* ; Ultrasonography