1.A Case of Ovarian Mullerian Mucinous Papillary Cystadenoma of Borderline Malignancy.
Jong Chan PARK ; Jung Hee AHN ; Kyu Wan LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(3):79-85
Mullerian Mucinous papillary Cyatadenernas of Borderline tumor(MMBT) is lined by mucinous epithelium of endocervical type and is characterized by papillae architecturally similer to those of serous horderline tumors, It has been described rarely in the literature, Thia case was reported with a brief review of the concerened literatures. It has important clinical and pathological diBerences from mucinous birderline tumors with intestinal differentiation, but has many similatities to mixed epithelial borderline tumora of Mulierian type. Recently, a case of MMBT in a 22 years old woman was experienced at our department. We presented this case with a brief review of literature.
Cystadenoma, Papillary*
;
Epithelium
;
Female
;
Humans
;
Mucins*
;
Young Adult
2.The value of preoperative CA125 assay in patients with pelvic masses .
Seung Il KIM ; Cheol UM ; Jin Sub AHN ; Byung Chan OH ; Jong Duck KIM
Korean Journal of Obstetrics and Gynecology 1992;35(3):372-378
No abstract available.
Humans
3.Molecular Analysis of Oculocutaneous Albinism Patients in Korea.
Ji Hwan HWANG ; Sang Woong YOUN ; Jong Seong AHN ; Kyu Han KIM ; Kyoung Chan PARK
Annals of Dermatology 1997;9(3):182-187
BACKGROUND: Oculocutaneous albinism (OCA) is a genetic disorder of the melanin pigment system in which melanin synthesis is reduced or absent in the skin, hair, and eyes. OCA is classified into two major types, and tyrosinase-related OCA can be produced by mutations of the structural gene for tyrosinase enzyme (TYR gene). OBJECTIVE: The purpose of this study was to analyze the segregation of mutant alleles of the TYR gene in tyrosinase-negative and tyrosinase-positive Korean OCA patients and families. METHODS: We amplified exon I, II, and III of the TYR gene of Korean OCA patients and their families by polymerase chain reactions (PCR), and analyzed the mutations by restriction fragment length polymorphism (RFLP) analysis in exon I and single-strand conformation polymorphism (SSCP) analyses in exon II and exon III. RESULTS: Two tyrosinase-negative cases showed mutations in exon I. Four tyrosinase-nega-tive cases and one tyrosinase-positive case showed mutations in exon II, and one tyrosinase-neg- ative case showed mutations in exon III. In summary, we found three kinds of mutation in four tyrosinase-negative OCA patients and one tyrsinase-positive OCA patient. CONCLUSIONS: RFLP and SSCP analysis can provide a basis for a rapid and sensitive screening system to detect TYR gene mutations of Korean OCA patients and their families.
Albinism, Oculocutaneous*
;
Alleles
;
Exons
;
Hair
;
Humans
;
Korea*
;
Mass Screening
;
Melanins
;
Monophenol Monooxygenase
;
Polymerase Chain Reaction
;
Polymorphism, Restriction Fragment Length
;
Polymorphism, Single-Stranded Conformational
;
Skin
4.Four cases of malignant mixed mullerian tumors of uterus.
Jung Hee AHN ; Jong Chan PARK ; Min Jung OH ; Hae Jung KIM ; Kyu Wan LEE
Korean Journal of Obstetrics and Gynecology 1993;36(8):3343-3350
No abstract available.
Uterus*
5.The Study of Tenascin Expression in Vitiligo.
Jong Seong AHN ; Kyung Chan PARK ; Young Gull KIM ; Kwang Hyun CHO ; Jung Wook SEO ; Duk Kyu CHUN
Korean Journal of Dermatology 1999;37(4):495-499
BACKGROUND: Defective adhesion and migration of melanocyte may be involved in pathogenesis of vitiligo. Tenascin, a glycoprotein of the extracellular matrix, has a role in cell adhesion and migration. It has been reported that abundant expression of tenascin in vitiligo lesion may inhibit melanocyte adhesion and migration. OBJECTIVE: To investigate the tenascin expression in vitiligo skin lesions and to compare with clinical findings. METHODS: We studied 9 patients with vitiligo. The expressions of tenascin were studied by immunahistochemieal techniques.
Cell Adhesion
;
Extracellular Matrix
;
Glycoproteins
;
Humans
;
Melanocytes
;
Skin
;
Tenascin*
;
Vitiligo*
6.A Study of the Safety and Efficacy of Children's Skin Products.
Ji Hwan HWANG ; Tae Eun KWON ; Jong Seong AHN ; Young Gull KIM ; Kyu Han KIM ; Kyoung Chan PARK
Korean Journal of Dermatology 1999;37(4):468-474
BACKGROUND: Atopic dermatitis, characterized by dry, flasky, easily irritated skin, is the most common form of dermatitis seen during childhood. Infants with atopic dermatitis and other eczematous conditions need special dermatologic care to hydrate their skin and to minimize contact with irritants or allergens. OBJECTIVE: The purpose of our study is to evaluate the safety and efficacy of the skin products developed for children. METHODS: Twenty-eight normal children and 26 children with atopic dermatitis were evaluated clinically after using following commercal skin products : (lotion, cream, shampoo, soap, face wash wash) for 2 weeks. Water content of the skin of 14 volunteers was measured serialy over 8 haurs at 2 hour intervals after the application of each skin product. The skin pH of 16 volunteers was also measured serialy over 60 minutes at 30 minute intervals after application. We performed visual skin erythema grading, skin erythema grading by dermaspectrometer, transepidermal water loss measurement, skin water content measurement, and keratinocyte morphology observation by D-squame after the application of the skin products to 13 volunteers for 4 days.
Allergens
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Carcinoma, Basal Cell
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Carcinoma, Squamous Cell
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Child
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Dermatitis
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Dermatitis, Atopic
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Erythema
;
Humans
;
Hydrogen-Ion Concentration
;
Infant
;
Irritants
;
Keratinocytes
;
Keratosis, Seborrheic
;
Skin*
;
Soaps
;
Volunteers
7.Effect of recruitment maneuver on arterial oxygenation in patients undergoing robot-assisted laparoscopic prostatectomy with intraoperative 15 cmH₂O positive end expiratory pressure.
Sowoon AHN ; Sung Hye BYUN ; Haeyoon CHANG ; Young Bin KOO ; Jong Chan KIM
Korean Journal of Anesthesiology 2016;69(6):592-598
BACKGROUND: This randomized, controlled study was designed to compare the effects of recruitment maneuvers (RMs) with a 15 cmH₂O positive end-expiratory pressure (PEEP) on the systemic oxygenation and lung compliance of patients with healthy lungs following robot-assisted laparoscopic prostatectomy (RALP). METHODS: Sixty patients undergoing a RALP with an intraoperative 15 cmH₂O PEEP were randomly allocated to an RM or a Control group. The patients in the RM group received a single RM through the application of a continuous positive airway pressure of 40 cmH₂O for 40 s 15 min after being placed in the Trendelenburg position. The arterial oxygen tension (PaO₂, primary endpoint) and the pulmonary dynamic and static compliances (secondary endpoints) were measured 10 min after the anesthetic induction (T1), 10 min after establishment of the pneumoperitoneum (T2), 10 min after establishment of the Trendelenburg position (T3), 10 min after the RM (T4), 60 min after the RM (T5), and 10 min after deflation of the pneumoperitoneum in the supine position (T6). RESULTS: The intergroup comparisons of the PaO₂ showed significantly higher values in the RM group than in the Control group at T4 and T5 (193 ± 35 mmHg vs. 219 ± 33 mmHg, P = 0.015, 188 ± 41 mmHg vs. 214 ± 42 mmHg, P = 0.005, respectively). However, the PaO₂ at T6 was similar in the two groups (211 ± 39 mmHg vs. 224 ± 41 mmHg, P = 0.442). Moreover, there were no statistical differences between the groups in the dynamic and static compliances of the lungs at any time point. CONCLUSIONS: The arterial oxygenation of the patients with a healthy lung function who had undergone a RALP with intraoperative 15 cmH₂O PEEP was improved by a single RM. However, this benefit did not last long, and it did not lead to an amelioration of the lung mechanics.
Continuous Positive Airway Pressure
;
Head-Down Tilt
;
Humans
;
Lung
;
Lung Compliance
;
Mechanics
;
Oxygen*
;
Pneumoperitoneum
;
Positive-Pressure Respiration*
;
Prostatectomy*
;
Supine Position
8.Measurement of the excessive stimulus time after the sensory threshold level during electric pulp testing.
Ki Chang NAM ; Seon Hui AHN ; Soo Chan KIM ; Deok Won KIM ; Seung Jong LEE
Journal of Korean Academy of Conservative Dentistry 2004;29(3):226-232
Use of electric pulp testing elicits painful response in vital teeth. In this study, we examined the excessive time from pain feeling to stimulation disconnection in clinical situation. D626D (Parkell Inc., USA.) scan type electric pulp tester was used in total of 23 young healthy individuals. Each of the right central incisors and first premolars were used as testing teeth. Stimulation disconnection was achieved by EMG in anterior belly of digastric muscle, finger span, and voice and the excessive stimulation time over the sensory threshold was recorded. As a result, we found that the short responses before the stimulation disconnection appeared following order; EMG, finger span, and voice. The EMG disconnection is suggested to be used to reduce the excessive stimulus time in electric pulp testing.
Bicuspid
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Fingers
;
Incisor
;
Sensory Thresholds*
;
Tooth
;
Voice
9.Posterior Approach to the Posterior Tibial Artery in Popliteal Arterial Aneurysm Repair: A case report.
Hong Gi LEE ; Chan Jong YOO ; Hee Chang AHN ; Young Soo NAM
Journal of the Korean Society for Vascular Surgery 1999;15(2):338-342
Surgical approach to the popliteal arterial aneurysm involves medial and posterior approaches. Posterior approach does not need division of hamstring muscle tendons and gastrocnemius head, which is necessary in medial approach for exposure of the entire popliteal artery (PA). Further, it has the advantage of harvesting the lesser saphenous vein without the need of additional incision. Posterior approach to vessels below PA was reported to be effective for bypass from PA to crural vessels in patients with limb ischemia. We report a case of popliteal aneurysm approached posteriorly. A 49-year-old male patient presented with a left popliteal mass and calf claudication for 2 years. Preoperative ultrasonography, MRI and angiography showed a thrombosed popliteal aneurysm. With the patient in left lateral position, the popliteal arterial aneurysm was exposed posteriorly, the lesser saphenous vein was harvested, the crural vessels were exposed by division of gastrocnemius and soleus muscles, and exclusion of the aneurysm and bypass from proximal PA to posterior tibial artery was done. Postoperatively, the patient experienced mild leg edema which soon disappeared, and he was discharged on the 23rd postoperative day. We found the posterior approach to the popliteal and proximal tibial artery to be simple and effective.
Aneurysm*
;
Angiography
;
Edema
;
Extremities
;
Head
;
Humans
;
Ischemia
;
Leg
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Muscles
;
Popliteal Artery
;
Saphenous Vein
;
Tendons
;
Tibial Arteries*
;
Ultrasonography
10.Anterolateral Intrumentation and Spinal Stabilzation of Thoracolumbar Burst Fracture.
Chan Jong YOO ; Dong Soo KANG ; Hwan Young CHUNG ; Young Bo KIM ; Sung Gi AHN ; Chuel Wan PARK ; Un LEE
Journal of Korean Neurosurgical Society 1996;25(6):1217-1222
Between March 1994 and March 1995, 10 patients with thoracolumbar burst fractures underwent a one-stage operation consisting of anterior decompression, reduction, bony fusion with iliac bone and stabilization with Kaneda device. The mean follow-up was 6.4 Months. Most patients with incomplete neurologic lesions showed postoperative improvement and were upgraded one or two steps in the Frankel scale. No patient showed neurological deterioration after surgery. Loss of reduction was 5.5 degree during follow-up period. Anterior decompression and strut fusion was used to effectively recover the neurological deficit and reduce the pain in a thoraco-lumbar burst fracture.
Decompression
;
Follow-Up Studies
;
Humans