Neurofibromatosis is an autosomal dominant abnormality that may affect multiple organ systems. The eyelids, the orbits, the adjacent tissues and bones may be involved with varying frequency and severity. The management of orbitotemporal neurofibromatosis depends very much on the type and severity of the orbital involvement and on the functional state of the eye. Experience with surgical management of orbitotemporal neurofibromatosis involved in the orbit, the temporal soft tissue and bone with blind eye is reported. The goal of surgery is tumor resection, reconstruction of the orbital socket, aesthetic eyelids, and insertion of the artificial prosthesis. A two stage approach is recommended. In the first stage, tumor is resected and the orbital socket is reconstructed with titanium mesh plate and cranial bone graft. After reconstruction of the orbital socket, galeal flap is rotated posteriorly to cover the mesh plate and canthopexy is accomplished. Mask lift is performed to enhance aesthetics. In the second stage, correction of the bulky eyelids is achieved and orbital space for insertion of the artificial prosthesis is reconstructed. Authors have managed a orbitotemporal neurofibromatosis with blind eye of a 41-year-old male using titanium mesh plate and bone graft with satisfactory results.
Adult ; Esthetics ; Eyelids ; Humans ; Male ; Masks ; Neurofibromatoses* ; Neurofibromatosis 1 ; Orbit ; Prostheses and Implants ; Titanium ; Transplants

No abstract available.
Behavior Therapy* ; Self-Injurious Behavior*

No abstract available.
Thorax* ; Ventilators, Mechanical*

The Q-switched ruby laser has been used in clinics since the early 1980s. It was tried to remove tattoos at first with good effects. Thereafter, some physicians reported the usefulness of the laser in the treatment of some kinds of pigmented lesions such as nevus of Ota, freckles and lentigines. The reason why the Q-switched ruby laser has a lot of effect on tattoos and some pigmented lesions is that the laser has the function of selective photothermolysis on those cutaneous lesions. The authors have treated 185 patients with tattoos and cutaneous pigmented lesions using the Q-switched ruby laser during last 4 years ago. Patients had tattoos, nevus of Ota, freckles, lentigines, melasma, postinflammatory hyperpigmentation, and were followed up over 5 months after the end of the laser treatment. The authors analysed the results and compared them with other's results in Caucasians, and we intended to present a guide of the treatment using Q-switched ruby laser in Koreans. The results were as follows 1. Tattoos showed good results after the treatment because the most of tattoos are black or dark blue in color and cheated by amateur. We repeated the laser treatments with the interval of 2 weeks. 2. Nevus of Ota, freckles and lentigines showed good results after treatment of the Q-switched ruby laser 3. Melasma showed no improvement after the treatment. 4. The treatment of postinflammatory hyperpigmentation using the Q-switched ruby laser must be confined within a part of the lesion at the first visit of patient, because the therapeutic effects were observed in some patients only and the degree of depigmention after treatment was diverse. 5. The most common complication after Q-switched ruby laser treatment was pigmentary change, including hyperpigmentation in most of the cases and hypopigmentation in some cases. However, there was no visible scar or remarkable change of skin texture in all of the cases.
Asian Continental Ancestry Group ; Cicatrix ; Humans ; Hyperpigmentation ; Hypopigmentation ; Lasers, Solid-State* ; Lentigo ; Melanosis ; Nevus of Ota ; Skin

This study was conducted to understand health status by general characteristic, and to find out relationship between social support and worker's health status. Health status was measured using SF-36(Medical Outcome Study Short Form 36), a 36 item self administered Instrument. The finding of this study were as follow; Mean scores of health status by sex were higher in male. The younger worker reported good health on physical functioning and role limitation-physical than did the older worker, but the older worker reported good health on social functioning and mental health. Mean scores of health status were higher in high income and white worker. When the relationship between social support and health status, social functioning, role limitation-emotion, mental health, vitality, general health were significantly related. Therefore we reviewed the evidence that socio-economic condition are associated with health status in this study, and that the strength of the social support was a important to maintain health.
Humans ; Male ; Mental Health ; Outcome Assessment (Health Care)

This study is concerned with the classifcation of Korean adult mandibular condyles on the basis of the shape of their anteroposterior view. The results were as follows ; 1. Morphological variations are classified into 4 groups. The percentage of each group has been : flat, 7.7% ; convex, 47.2% ; angled, 14.8% ; round, 30.3%. 2. The location of the highest point were as follows : in the lateral third, 15.5% ; middle third, 80.3% ; medial third, 4.2%. 3. The maximum transverse diameter and greatest height were 20.3±2.4mm and 6.5±1.5mm, respectively.
Adult* ; Classification* ; Humans ; Mandibular Condyle*

The effects and interactions of 4 beta-phorbol 12,13-dibutyrate(PDB) and polymyxin B(PMB) with adenosine on the electrically-evoked acetylcholine(ACh) release were studied in rat hippocampus. Slices from rat hippocampus were equilibrated with 3H-choline and the release of the labeled product, 3H-ACh, which was evoked by electrical stimulation(3Hz, 2ms, 5Vcm-1, rectangular pulses) was measured. PDB(0.3-10 micorM), a selective protein kinase C(PKC) activator, increased the evoked ACh release in a dose related fashion with an increase in the basal rate of release. The effects of 1(M PDB were significantly inhibited by 0.3 micorM tetrodotoxin(TTX) pretreatment or Ca++-free medium. PMB(0.03-1mg), a selective PKC inhibitor, decreased the ACh release in a dose dependent manner with an increase in the basal rate of release. Adenosine(1-10 micorM) decreased the ACh release without changing the basal rate or release, and this effect was significantly inhibited by 8-cyclopentyl-1,3-dipropylxanthine(2 micorM), a selective A1-receptor antagonist treatment. However, adenosine effects were not affected by PDB and PMB. These results indicate that the PKC play a role in the ACh release in the rat hippocampus but is not involved in the post-receptor mechanism of the A1-adenosine receptor.
Acetylcholine* ; Adenosine ; Animals ; Hippocampus* ; Polymyxin B ; Polymyxins ; Protein Kinase C* ; Protein Kinases* ; Rats* ; Tetrodotoxin

Immunological effect of the extract (KM-110) from Korean mistletoe (Viscum album coloratum) was examined. Lymphocytes obtained from KM-110-administrated mice showed increased responsiveness to mitogens, concanavalin-A (Con.A) and lipopolysaccharide (LPS). In order to study cytokine induct ability of the KM-110, macrophages from the Balb/c mice were cultivated in the medium containing the extract. the macrophages were shown to induce secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin 1 and 6 (IL-1, IL-6) and interferon-gamma (INF-gamma). We then tested antitumor activity of the macrophages activated by the KM-110. Peritoneal macrophages harvested from the KM110-treated Balb/c mice exhibited cytotoxicity against the syngeneic 3LL carcinoma cells. ...continue...
Animals ; Interferon-gamma ; Interleukin-1 ; Lymphocytes ; Macrophages ; Macrophages, Peritoneal ; Mice ; Mistletoe* ; Mitogens ; Tumor Necrosis Factor-alpha ; Viscum album* ; Viscum*

A case of right simple unilateral renal ectopia with left malrotated kidney in 26 years old female is presented with a brief review of literature. Right ectopic kidney was located between 4th and 5th lumber vertebra Numerous aberrant vessels of ectopic kidney disclosed during nephroureterectomy.
Adult ; Female ; Humans ; Kidney ; Spine

PURPOSE: The aim of this study is to analyze various clinical characteristics of gastrointestinal carcinoid tumors including their symptoms, diagnoses and treatment strategies. METHODS: Medical records of 36 cases of gastrointestinal carcinoid tumors diagnosed at Bundang CHA Hospital from March 2000 to February 2008 were reviewed and analyzed retrospectively. RESULTS: The mean age of patients at diagnosis was 50 years old. Frequent location of the tumors was as follows- rectum, duodenum, appendix, stomach, colon, and small bowel. The size of tumor varied and the mean size was measured 9.0 mm. Any specific symptoms did not arise nor were they detected among most of the patients at the time of diagnosis. Endoscopic resection of gastrointestinal carcinoid tumor was undergone in 27 cases, while 13 cases were resected with surgical procedures. Surgical procedures performed were appendectomy in 4 cases, transanal resection in 3 cases, low anterior resection in 3 cases, pancreaticoduodenectomy in 1 case, duodenotomy with mass excision in 1 case, ileotomy with mass excision in 1 case. One case of recurrence was reported during the follow-up period. CONCLUSION: Gastrointestinal carcinoid tumors have various clinical presentations and the results are highly variable and also individualized according to the site of the primary tumor. It leads to a multiplicity of treatment options for the patients. The expertise of surgeons and endoscopic physicians should be combined for proper management strategies and effective results of carcinoid tumors of gastrointestinal tract treatment.
Appendectomy ; Appendix ; Carcinoid Tumor ; Colon ; Duodenum ; Follow-Up Studies ; Gastrointestinal Tract ; Humans ; Medical Records ; Pancreaticoduodenectomy ; Rectum ; Recurrence ; Stomach