1.Septic monoarthritis and osteomyelitis in an elderly man following Klebsiella pneumoniae genitourinary infection: case report.
Annals of the Academy of Medicine, Singapore 2006;35(2):100-103
INTRODUCTIONKlebsiella pneumoniae septic arthritis and osteomyelitis, albeit uncommon in adults, are important sites of disseminated infection. Many case reports have shown K. pneumoniae as a cause of nosocomial transmitted septic arthritis in neonates and children. We report a rare case of an elderly patient with K. pneumoniae genitourinary infection spreading to the liver and other extra hepatic sites like the prostate and peripheral joint.
CLINICAL PICTUREThe patient presented with a short history of general malaise, fever and urinary symptoms, associated with an acute monoarthritis of the ankle. On admission, he was in septic shock. Investigations suggested an infective cause, as evidenced by raised total white cell count and pyuria. K. pneumoniae was cultured from both urine and ankle synovial fluid. Imaging confirmed multiple liver and prostatic abscesses, as well as osteomyelitis of the foot bones adjacent to the ankle.
TREATMENTTreatment in this case included surgical drainage of the affected joint and surrounding soft tissue structures, in addition to a 6-week course of systemic antibiotics.
OUTCOMEThe patient had good clinical response following treatment. In addition, we noted a normalisation of his laboratory parameters and resolution of the intraabdominal and pelvic abscesses.
CONCLUSIONThis case emphasises the importance of timely and accurate diagnosis followed by appropriate treatment in disseminated K. pneumoniae infection to prevent significant morbidity and mortality.
Aged ; Ankle Joint ; microbiology ; surgery ; Anti-Bacterial Agents ; therapeutic use ; Arthritis, Infectious ; diagnosis ; microbiology ; therapy ; Combined Modality Therapy ; Drainage ; Foot Bones ; microbiology ; Humans ; Klebsiella Infections ; diagnosis ; therapy ; Klebsiella pneumoniae ; Liver Abscess ; microbiology ; Magnetic Resonance Imaging ; Male ; Osteomyelitis ; drug therapy ; epidemiology ; microbiology ; surgery ; Prostatic Diseases ; microbiology ; Synovial Fluid ; microbiology ; Tomography, X-Ray Computed ; Urinary Tract Infections ; drug therapy ; microbiology
2.Appropriate oral antibiotics for bone and joint infections based on the susceptibility of clinical Staphylococcus aureus isolates.
Chang Seop LEE ; Jeong Hwan HWANG ; Jae Hoon LEE ; Soo Kyeong SONG ; Ji Hyun CHO ; Ju Hyung LEE
The Korean Journal of Internal Medicine 2015;30(2):262-264
No abstract available.
Administration, Oral
;
Aged
;
Anti-Bacterial Agents/*administration & dosage
;
Bone Diseases, Infectious/diagnosis/*drug therapy/microbiology
;
Drug Therapy, Combination
;
Female
;
Hospitals, University
;
Humans
;
Joint Diseases/diagnosis/*drug therapy/microbiology
;
Male
;
Microbial Sensitivity Tests
;
Middle Aged
;
Republic of Korea
;
Staphylococcal Infections/diagnosis/*drug therapy/microbiology
;
Staphylococcus aureus/*drug effects/isolation & purification
;
Treatment Outcome