1.Radiotherapy in Hodgkin's disease.
Young Hwan PARK ; Chang Ok SUH ; Gwi Eon KIM ; John Kyu LOH JUHN
Journal of the Korean Cancer Association 1992;24(2):277-287
No abstract available.
Hodgkin Disease*
;
Radiotherapy*
2.Effectiveness of postoperative adjuvant treatment between radiation alone and chemotherapy plus radiation in locally advanced breast cancer.
Kyung Ran PARK ; John Kyu LOH JUHN ; Chang Ok SUH ; Gwi Eon KIM ; Eun Hee KOH ; Byung Soo KIM ; Kyung Sik LEE
Journal of the Korean Cancer Association 1991;23(1):107-119
No abstract available.
Breast Neoplasms*
;
Breast*
;
Drug Therapy*
3.Phase II trial of 5-FU, etoposide, cisplatin (FEP) combination chemotherapy in unresectable non-small cell lung cancer.
Jin Hyuk CHOI ; Hyun Cheol CHUNG ; Dong Jip KIM ; Je Yol OH ; Joon CHANG ; Eun Hee KOH ; Joo Hang KIM ; Jae Kyung RHO ; Sung Kyu KIM ; Won Young LEE ; Gwi Eon KIM ; John Kyu LOH JUHN
Journal of the Korean Cancer Association 1991;23(1):120-130
No abstract available.
Carcinoma, Non-Small-Cell Lung*
;
Cisplatin*
;
Drug Therapy, Combination*
;
Etoposide*
;
Fluorouracil*
4.Management of rocoregional recurrent breast cancer.
Kyung Ran PARK ; Jong Young LEE ; Chang Geol LEE ; Chang Ok SUH ; John Kyu LOH JUHN ; Gwi Eon KIM ; Soo Gon KIM ; Won Yong OH ; Eun Hee KOH ; Byung Soo KIM
Journal of the Korean Cancer Association 1992;24(5):684-694
No abstract available.
Breast Neoplasms*
;
Breast*
5.A phase II trial of combined sequential FP (5-FU+cisplatin) chemotheraphy and radiotherapy in locally advanced unresectable esophageal cancer.
Jong Won HA ; Hyun Cheol CHUNG ; Dong Lip KIM ; Jin Hyuk CHOI ; Nae Choon YOO ; Eun Hee KOH ; Joo Hang KIM ; Jae Kyung ROH ; Gwi Eon KIM ; John Kyu LOH JUHN ; Byung Soo KIM
Journal of the Korean Cancer Association 1991;23(2):307-314
No abstract available.
Esophageal Neoplasms*
;
Radiotherapy*
6.Effects of Radiofrequency Induced local Hyperthermia on Normal Canine Liver.
Chang Ok SUH ; John Juhn Kyu LOH ; Jin Sil SUNG ; Sun Rock MOON ; Hyung Sik LEE ; Hyun Soo SHIN ; Sung Sil CHU ; Gwi Eon KIM ; Chan Il PARK ; Eun Kyung HAN
Journal of the Korean Society for Therapeutic Radiology 1991;9(1):37-46
In order to assess the effects of radiofrequency-induced local hyperthermia on the normal liver, histopathologic findings and biochemical changes after localized hyperthemia in canine liver were studied. Hyperthermia was externally administered using the Thermotron RF-8 (Yamamoto Vinyter Co., Japan; Capacitive type heating machine) with parallel opposed electrodes. Thirteen dogs were used and allocated into one control group (N=3) and two treatment groups according to the treatment temperature. GroupI(N=5) was heated with 42.5+/-0.5degree C for 30 minutes, and GroupII(N=5) was heated with 45+/-0.5degree C for 15-30 minutes. Samples of liver tissue were obtained through a needle biopsy immediately afterhyperthermia and 7, 14 and 28 days after treatment and examined for SGOT, SGPT and alkaline phosphatase. Although SGOT and SGPT were elevated after hyperthermia in both groups (three of five in each group), there was no liver cell necrosis or hyperthermia related mortality in GroupI. A hydropic swelling of hepatocytes was prominent histologic finding. Hyperthermia with 45degree C for 30 minutes was fatal and showed extensive liver cell necrosis. In conclusion, liver damage day heat of 42.5+/-0.5degree C for 30 minutes is reversible, and liver damage by heat of 45+/-0.5degree C for 30 minutes can be fatal or irreversible. However, these results cannot be applied directly to human trial. Therefore, in order to apply hyperthermic treatment on human liver tumor safely, close observation of temperature with proper thermometry is mandatory. Hyperthermic treatment should be confined to the tumor area while sparing a normal liver as much as possible.
Alanine Transaminase
;
Alkaline Phosphatase
;
Animals
;
Aspartate Aminotransferases
;
Biopsy, Needle
;
Dogs
;
Electrodes
;
Fever
;
Heating
;
Hepatocytes
;
Hot Temperature
;
Humans
;
Hyperthermia, Induced*
;
Japan
;
Liver*
;
Mortality
;
Necrosis
;
Thermometry
Result Analysis
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