1.A Case of Tuberculous Peritonitis in Pregnancy.
John Ik LEE ; Min Yeon KWON ; Sung Wook SONG ; Choo Jin PARK ; Zong Soo MOON ; Soo Hyung SEO ; Yang Suh PARK
Korean Journal of Obstetrics and Gynecology 2000;43(1):132-136
The tuberculous peritonitis, especially in pregnancy, is very rare and difficult to diagnose since there is no diagnostic clue and limitation of diagnostic means. The clinical features may vary such as fever, chill, tachycardia, abdominal tenderness or rebound tenderness which are not controlled easily with antibiotics. It is possible to diagnose by AFB culture and biopsy through exploro-laparotomy which is done due to uncontrolled symptoms even to unstable vital signs. It's clinical symptoms and signs are dramatically improved with antituberculotic therapy. Recently we have experienced a case of tubeculous peritonitis at 29 weeks gestation which was diagnosed through exploro-laparotomy including cesarean section. So we report this case with a brief review of literature
Anti-Bacterial Agents
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Biopsy
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Cesarean Section
;
Female
;
Fever
;
Peritonitis
;
Peritonitis, Tuberculous*
;
Pregnancy*
;
Tachycardia
;
Vital Signs
2.A Case of Primary Papillary Serous Carcinoma of the Peritoneum.
Min Yeon KWON ; John Ik LEE ; So Young WOO ; Kyu Ha CHOI ; Choo Jin PARK ; Duck Hwan KIM ; Zong Soo MOON ; Soo Hyung SEO ; Yang Suh PARK
Korean Journal of Obstetrics and Gynecology 1999;42(8):1815-1819
Primary papillary serous carcinoma of the peritoneum(PPSCP) is vere rare. It has been suggested that PPSCP derives from embryonal coelomic epithelium with m llerian ducts potential. PPSCP can develop from a single or multicentric focus. The clinical and histologic disease entities are similar to those of primary papillary serous carcinoma of the ovary, but PPSCP involves the ovarian surface only minimally(microscopic disease) or spares the ovaries entirely. We have experienced a case of primary papillary serous carcinoma of the peritoneum and report this case with brief review of the concerned literature.
Epithelium
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Female
;
Ovary
;
Peritoneum*
3.Performance Evaluation of the DxC 700 AU Chemistry Analyzer in Hemoglobin A1c Measurement
Yu Jeong CHOI ; Hyein KANG ; Chan-Ik CHO ; John Hoon RIM ; Sang-Guk LEE ; Jong-Baeck LIM
Annals of Laboratory Medicine 2023;43(2):167-173
Background:
Accurate measurement of glycated hemoglobin (HbA1c) is crucial for a diabetes diagnosis and subsequent patient management. The detection method and presence of variant Hb can interfere with HbA1c measurements. We evaluated the HbA1c-measuring performance of the DxC 700 AU (Beckman Coulter, Brea, CA, USA) immunoassay-based device in comparison with another immunoassay device and the reference method.
Methods:
A total of 120 normal and 14 variant Hb samples were analyzed using the Cobas c 513 (Roche Diagnostics, Mannheim, Germany) and DxC 700 AU analyzers. Variant Hb samples were also analyzed using the reference method, along with 20 normal samples. The accuracy, precision, linearity, and carryover were determined.
Results:
DxC 700 AU results strongly correlated with those of Cobas c 513 and exhibited accuracy in comparison with the reference method. The within-run, between-run, between-day, and total imprecision (%CV) values for the low- and high-concentration control materials were below 2%. The results of DxC 700 AU were linear over a wide HbA1c range (3.39%–18.30%). Although DxC 700 AU performed well in the presence of variant Hb, the HbA1c concentration was underestimated in the presence of fetal Hb. The possibility of interference from a high HbH proportion could not be ruled out.
Conclusions
The overall analytical performance of DxC 700 AU was acceptable. The device is accurate, precise, and linear over a wide HbA1c concentration range. Although DxC 700 AU results highly correlated with those of Cobas c 513, caution should be exercised in cases of high HbF and HbH concentrations.
4.New clinical score for disease activity at diagnosis in Langerhans cell histiocytosis.
Won ik CHOI ; You Cheol JEONG ; Sun Young KIM ; So Dam KIM ; John Paul PRIBIS ; Hee Jin KIM ; Kyung Nam KOH ; Ho Joon IM ; Young Ho LEE ; Jong Jin SEO
Korean Journal of Hematology 2011;46(3):186-191
BACKGROUND: The clinical presentation and course of Langerhans cell histiocytosis (LCH) are variable, ranging from an isolated, spontaneously remitting bone lesion to multisystem disease with risk organ involvement. Treatment of LCH ranges from a wait-and-see attitude to intensive multidrug therapy and, in some cases, bone marrow transplantation. It is necessary to develop an objective score for assessing disease activity in patients with LCH. We propose a new clinical scoring system to evaluate disease activity at diagnosis that can predict the clinical outcomes of LCH and correlate it with clinical courses. METHODS: Clinical data, obtained from children diagnosed with LCH at Asan Medical Center and Hanyang University Hospital between March 1998 and February 2009, were studied retrospectively. The scoring system was developed according to the basic biological data, radiological findings, and physical findings and applied to a database containing information on 133 patients. RESULTS: The median age of the 133 patients (74 male, 59 female) was 52 months (range, 0.6-178 months), and LCH was diagnosed based on CD1a positivity. At diagnosis, the score distributions were highly asymmetrical: the score was between 1 and 2 in 75.9% of cases, 3-6 in 15.8%, and greater than 6 in 8.3%. Initial scores above 6 were highly predictive of reactivation and late complications. CONCLUSION: This new LCH disease activity score provides an objective tool for assessing disease severity, both at diagnosis and during follow-up.
Bone Marrow Transplantation
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Child
;
Follow-Up Studies
;
Histiocytosis
;
Histiocytosis, Langerhans-Cell
;
Humans
;
Langerhans Cells
;
Male
;
Retrospective Studies