1.Cut-Off Values of the Post-Intensive Care Syndrome Questionnaire for the Screening of Unplanned Hospital Readmission within One Year
Jiyeon KANG ; Yeon Jin JEONG ; Jiwon HONG
Journal of Korean Academy of Nursing 2020;50(6):787-798
Purpose:
This study aimed to assign weights for subscales and items of the Post-Intensive Care Syndrome questionnaire and suggest optimal cut-off values for screening unplanned hospital readmissions of critical care survivors.
Methods:
Seventeen experts participated in an analytic hierarchy process for weight assignment. Participants for cut-off analysis were 240 survivors who had been admitted to intensive care units for more than 48 hours in three cities in Korea. We assessed participants using the 18-item Post-Intensive Care Syndrome questionnaire, generated receiver operating characteristic curves, and analysed cut-off values for unplanned readmission based on sensitivity, specificity, and positive likelihood ratios.
Results:
Cognitive, physical, and mental subscale weights were 1.13, 0.95, and 0.92, respectively.Incidence of unplanned readmission was 25.4%. Optimal cut-off values were 23.00 for raw scores and 23.73 for weighted scores (total score 54.00), with an area of under the curve (AUC) of .933 and .929, respectively. There was no significant difference in accuracy for original and weighted scores.
Conclusion
The optimal cut-off value accuracy is excellent for screening of unplanned readmissions. We recommend that nurses use the Post-Intensive Care Syndrome Questionnaire to screen for readmission risk or evaluating relevant interventions for critical care survivors.
2.Effect of Bicarbonate Supplementation on Renal Function and Nutritional Indices in Predialysis Advanced Chronic Kidney Disease.
Jiwon JEONG ; Soon Kil KWON ; Hye Young KIM
Electrolytes & Blood Pressure 2014;12(2):80-87
Current practice guidelines recommend alkali therapy in patients with chronic kidney disease (CKD) and metabolic acidosis to prevent complications. This study aims to investigate the effect of oral sodium bicarbonate supplementation on the progression of renal function and nutritional indices in patients with predialysis advanced CKD. Forty patients with predialysis stage 5 CKD(estimated glomerular filtration rate, eGFR <15mL/min per 1.73m2) and 40 patients with stage 4 CKD (eGFR 15 to 30mL/min per 1.73m2) who had a total CO2 less than 22mEq/L were assigned into the bicarbonate treatment group or control group for 12 months. In stage 4 CKD, there were significant differences in the changes of eGFR during the study between the treatment group and the control group (-2.30+/-4.49 versus -6.58+/-6.32mL/min/1.73m2, p<0.05). However, in stage 5 CKD, there were no significant differences in the change of eGFR during the study between the two groups (-2.10+/-2.06 versus -3.23+/-1.95mL/min/1.73 m2).There were no significant differences in the changes of nutritional indices such as albumin, prealbumin, transferrin, total lymphocyte count (TLC), and Ondodera's prognostic nutritional index (OPNI) during the study between the two groups. In stage 5 CKD, there were significant differences in the changes of TLC and OPNI between the two groups. In conclusion, our results demonstrate that bicarbonate supplementation slows the rate of decline of renal function in stage 4 CKD and improves nutritional indices in stage 5 CKD. Alkali therapy in advanced CKD may have beneficial effect on renal function and malnutrition.
Acidosis
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Alkalies
;
Glomerular Filtration Rate
;
Humans
;
Lymphocyte Count
;
Malnutrition
;
Nutrition Assessment*
;
Prealbumin
;
Renal Insufficiency, Chronic*
;
Sodium Bicarbonate
;
Transferrin
3.Task Analysis of the Job Description of Rehabilitation Nurse based on DACUM.
Heeyoung SO ; Jeong Wha KIM ; Jiwon PARK ; Nan Young LIM
Korean Journal of Rehabilitation Nursing 2009;12(1):16-29
PURPOSE: The aim of this study was to develop and to analyze the duty and the task of rehabilitation nurse in Korea. METHOD: The definition of rehabilitation nurse and job description was developed based on developing curriculum(DACUM) by panels who have experienced in DACUM analysis and rehabilitation nursing. 228 nurses who were working at rehabilitation centers and rehabilitation unit in general hospitals were participated. The questionnaire included frequency, importance, and difficulty of duties and tasks. The data were collected in March and April 2009, analyzed by descriptive statistics. RESULTS: The job description of rehabilitation nurse in Korea revealed 11 duties, and 61 tasks. On the all 11 duties, the highest duty in frequency and importance was direct nursing care (2.47+/-.31, 2.77+/-.28) and the highest duty in difficulty was self-development (2.39+/-.48). Among the tasks of duties 'direct nursing care' in 'manage medication' (2.87+/-.35) in frequency, the task 'prevent and manage bedsore' (2.91+/-.31) of duty 'direct nursing care' in importance, and 'cope emergency situations' (2.72~.49) of duty direct nursing care in difficulty showed the highest degree. CONCLUSION: The political efforts for the legislation of role and task of rehabilitation nurse were needed.
Emergencies
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Hospitals, General
;
Humans
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Job Description
;
Korea
;
Nurse Practitioners
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Nursing Care
;
Surveys and Questionnaires
;
Rehabilitation Centers
;
Rehabilitation Nursing
4.Association between green tea consumption and metabolic syndrome among Korean adults: results from the Health Examinees study
Hyeonjin CHO ; Sunwoo HAN ; Jiwon JEONG ; Hyein JUNG ; Sangah SHIN
Journal of Nutrition and Health 2023;56(1):70-85
Purpose:
Several studies have been conducted on the relationship between green tea intake and metabolic syndrome. However, compared to the studies carried out internationally, there is inadequate research on the relationship between domestic green tea consumption and metabolic syndrome. Therefore, in this study, the general characteristics of Koreans according to their green tea intake and its association with metabolic syndrome were examined.
Methods:
A total of 44,611 subjects were included in the study, and analysis was carried out using data from the Korean Genome and Epidemiology Study (KoGES) for Korean adults aged 40 or older. Green tea consumption was estimated using 106 verified food frequency questionnaires (FFQ). Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) parameters. After adjusting for confounding variables by performing a Cox regression analysis, the association between green tea consumption and metabolic syndrome was confirmed through the hazard ratio (HR) and 95% confidence interval (CI).
Results:
The average incidence of metabolic syndrome was 18.7% (20.8% in men and 17.8% in women). Compared to those who drank almost no green tea, in subject groups consuming more than one cup of green tea a day, the metabolic syndrome incidence was significantly reduced by 15% (HR, 0.85; 95% CI, 0.74–0.96; p trend = 0.0200) among men and by 19% (HR, 0.81; 95% CI, 0.73–0.90; p trend < 0.0001) among women. In addition, the biomarkers related to metabolic syndrome also tended to decrease overall in these groups.
Conclusion
This study concluded that as the intake of green tea increased, the incidence of metabolic syndrome and related indicators decreased. Therefore, green tea intake is believed to have a positive effect on the prevention and management of the metabolic syndrome.
5.Development of a campus-based intervention program to strengthen food literacy among university students: A qualitative formative study
Eunji KO ; Eunjin JANG ; Jiwon SIM ; Minjeong JEONG ; Sohyun PARK
Korean Journal of Community Nutrition 2023;28(6):495-508
Objectives:
This study aimed to develop a campus-based intervention program to enhance food literacy (FL) among university students.
Methods:
In the initial phase, we conducted a literature review of FL intervention studies and held in-depth interviews with university students to identify facilitators and barriers to improving and practicing FL. Expert counseling sessions were conducted with nutrition education, marketing, and service design professionals. The results of this phase led to the creation of an initial curriculum draft. In the second phase, a follow-up survey was conducted with young adults to assess the acceptability of the developed curriculum. After the follow-up survey, additional meetings were conducted with the aforementioned experts, and the curriculum was further refined based on their input.
Results:
An 11-week FL intervention program was devised using constructs from the Social Cognitive Theory. The weekly curriculum consisted of 90-min theory-based and 90-min hands-on experience sessions. Three primary aspects of FL were covered: nutrition and food safety, cultural and relational dimensions, and socio-ecological aspects. Program highlights included cooking sessions for crafting traditional Korean desserts, lectures on animal welfare, insights into zero-waste practices, and communal eating experiences. Based on the study team’s previous research, the program also addressed mindful eating, helping participants understand the relationship with their eating habits, and providing strategies to manage negative emotions without resorting to food. Yoga sessions and local farm visits were incorporated into the curriculum to promote holistic well-being.
Conclusions
This study elucidated the comprehensive process of creating a campus-based curriculum to enhance FL among university students, a group particularly susceptible to problematic eating behaviors and low FL levels. The developed program can serve as a blueprint for adaptation to other campuses seeking to bolster students’ FL.
6.Expression of Gpnmb in NK Cell Development from Hematopoietic Stem Cells.
Nara SHIN ; Jiwon LEE ; Jiwon LEE ; Mira JEONG ; Mi Sun KIM ; Suk Hyung LEE ; Suk Ran YOON ; Jin Woong CHUNG ; Tae Don KIM ; Inpyo CHOI
Immune Network 2008;8(2):53-58
BACKGROUND: Molecular mechanisms of natural killer (NK) cell development from hematopoietic stem cells (HSCs) have not been clearly elucidated, although the roles of some genes in NK cell development have been reported previously. Thus, searching for molecules and genes related NK cell developmental stage is important to understand the molecular events of NK cell development. METHODS: From our previous SAGE data-base, Gpnmb (Glycoprotein non-metastatic melanoma protein B) was selected for further analysis. We confirmed the level of mRNA and protein of Gpnmb through RT-PCR, quantitative PCR, and FACS analysis. Then we performed cell-based ELISA and FACS analysis, to know whether there are some molecules which can bind to Gpnmb. Using neutralizing antibody, we blocked the interaction between NK cells and OP9 cells, and checked IFN-gamma production by ELISA kit. RESULTS: Gpnmb expression was elevated during in vitro developmental stage and bound to OP9 cells, but not to NK precursor cells. In addition, we confirmed that the levels of Gpnmb were increased at NK precursor stage in vivo. We confirmed syndecan4 as a candidate of Gpnmb's binding molecule. When the interaction between NK cells and OP9 cells were inhibited in vitro, IFN-gamma production from NK cells were reduced. CONCLUSION: Based on these observations, it is concluded that Gpnmb has a potential role in NK cell development from HSCs.
Antibodies, Neutralizing
;
Enzyme-Linked Immunosorbent Assay
;
Hematopoietic Stem Cells
;
Killer Cells, Natural
;
Melanoma
;
Polymerase Chain Reaction
;
RNA, Messenger
;
Syndecan-4
7.The Ethanolic Extract of Chrysanthemum morifolium Ramat Flower Activates Parasympathomimetic and Anti-inflammatory Effects for Prevention of Presbyopia
Amitesh SHARMA ; Shivani DEVI ; Kartic ; Nattan STALIN ; Jiwon LIM ; Jiwon CHOI ; Jisun KIM ; Mi-Young JEONG ; Sung-Joon LEE ; Tae-Sik PARK
Natural Product Sciences 2024;30(1):20-29
Presbyopia is characterized by a loss of the accommodative ability of the eye that negatively affects vision-aided health-related quality of life. Local inflammation in the eye diminishes parasympathetic cholinergic stimulation and contraction of the iris and ciliary muscle in the eyes via the muscarinic (cholinergic) receptor.Along with the cholinergic agent, a non-steroidal anti-inflammatory agent is often integrated to ameliorate presbyopia. Chrysanthemum morifolium belongs to the Asteraceae. We examined whether Chrysanthemum morifolium flower extract (CME) has parasympathomimetic and anti-inflammatory activity in HLE-B3 human lens epithelial cells and RAW 264.7 macrophages. CME induced time- and dose-dependent production of IP 1 and Ca 2+ accumulation in HLE-B3 cells. In the LPS-induced inflammatory response, CME treatment downregulated inducible nitric oxide synthase (iNOS) and nitric oxide in RAW 264.7 macrophages. CME downregulated the levels of interleukin-1β (IL-1β) and interleukin-6 (IL-6) with no change in TNF-α levels. In addition, the phosphorylation of JNK and p38 was reduced with no change in ERK by CME in LPS-treated cells. These findings suggest that the parasympathetic and anti-inflammatory efficacy of CME can be applied to develop therapeutics against presbyopia.
8.A Case of Constrictive Pericarditis due to Immunoglobulin G4-Related Disease.
Jiwon SEO ; In Ji SONG ; Sak LEE ; Hyeon Joo JEONG ; Hye Min KIM ; Beom Seok KOH ; Sung Ha PARK
Korean Circulation Journal 2015;45(2):161-164
Immunoglobulin G4-related disease (IgG4-RD) can involve any organ. The majority of reported cases involve IgG4-RD of the biliary tract or pancreas, while only two cases of pericarditis have been reported. A 58-year-old man visited the outpatient clinic of our institution with a seven-day history of progressive dyspnea. Based on his transthoracic echocardiogram and transesophageal echocardiogram, he was diagnosed with constrictive pericarditis. The histopathology of his pericardiectomy revealed the cause of constrictive pericarditis to be IgG4-RD. Prednisolone (40 mg) was initiated after the pericardiectomy. As the patient's symptoms resolved, he was discharged and followed-up on an outpatient basis. This is the first case report of constrictive pericarditis caused by IgG4-RD in Korea.
Ambulatory Care Facilities
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Biliary Tract
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Dyspnea
;
Humans
;
Immunoglobulin G
;
Immunoglobulins*
;
Inflammation
;
Korea
;
Middle Aged
;
Outpatients
;
Pancreas
;
Pericardiectomy
;
Pericarditis
;
Pericarditis, Constrictive*
;
Prednisolone
9.Recurrence of Classic Scabies in a Patient Who had Unchanged Tie String of the T-Cannula
Jiwon JUNG ; Jihye JEONG ; Min Jee HONG ; Eun Ok KIM ; Min Jae KIM ; Sung Eun CHANG ; Sung-Han KIM
Infection and Chemotherapy 2022;54(2):378-381
A 64-year old woman who underwent lung transplantation and had T-cannula contracted classic scabies from her daughter. The patient was treated with 5% permethrin 10 times and had two consecutive negative follow-up microscopic examinations. However, the patient had recurrent symptoms and diagnosed with recurrent classic scabies 22 days after the last treatment. Unchanged tie string and unapplied topical agent around the T-cannula skin lesion may be reasons for recurrence. Thus, accurate application of topical treatment and changing the tie string of the t-cannula is needed to prevent a recurrence.
10.Sex Differences in Attitudes Toward Marriage and Childbearing Based on the Assumption of Being BRCA1/2 Mutation Carriers Among Young People
Jiwon JEONG ; Boyoung PARK ; Dongwon KIM ; Jiyoung KIM ; Bom-Yi LEE ; Junghyun YOON ; Sung-Won KIM
Journal of Breast Cancer 2022;25(3):233-243
Purpose:
This study investigated changes in attitudes toward marriage and childbearing assuming a BRCA1/2 mutation carrier status among healthy, unmarried individuals in Korea.
Methods:
A nationally representative sample of healthy, unmarried individuals aged 20–39 years was surveyed. A questionnaire on marriage and childbearing intentions was administered to the participants before and after providing them with information on BRCA1/2 mutation carriers’ breast and ovarian cancer risks and their autosomal dominant inheritance pattern. The participants were asked about their attitudes toward childbearing through preimplantation genetic diagnosis (PGD).
Results:
Of the participants who initially wanted to marry, the assumption that they or their partners had BRCA1/2 mutation caused 25.3% to no longer want to get married and 36.2% to change their attitude from wanting to bear children to no longer wanting them. Females were more likely than males to change their attitudes toward marriage and childbearing. The participants who had negative attitudes toward genetic testing were more likely to change their attitudes regarding marriage and childbearing than those who were favorable toward both disclosure and testing. More than 50% of the participants who did not want children were willing to bear children through PGD when it was assumed that they were BRCA mutation carriers.
Conclusion
On the assumption of being carriers, general, young, and healthy females were more likely than males to negatively change their attitudes toward marriage and childbearing. Public education on the implications of living with mutation carriers and reproductive options may be required.