Objective:To establish a predictive model of psychological crisis based on the machine learning random forest algorithm, and to analyze the influencing factors of psychological crisis among adole scent.Methods:A total of 1 417 middle school students were surveyed using cluster sampling in two phases, in November 2020 and June 2021.Demographic data, symptom factors, protective factors were collected in the first investigation, and depression and suicide risk were measured in the second investigation. The criteria for psychological crisis were moderate to severe depression(depression score≥15) and high suicide risk(suicide risk score≥7) in the second measurement. SPSS 24.0 software was used for statistical analysis of variables, and the random forest machine learning predictive model for psychological crisis was established by using R version 4.1.1 software, and the high-estimating factors of adolescent psychological crisis were analyzed.Results:(1) The detection rate of moderate to severe depression was 10.02%(142/1 417), the detection rate of high suicide risk was 30.77%(436/1 417), and detection rate of the psychological crisis was 8.19%(116/1 417).(2) The sensitivity and specificity of psychological crisis prediction model were 0.79, 0.82, positive predictive value was 0.82, negative predictive value was 0.79, accuracy was 0.80 and area under curve was 0.88. (3) The top 10 characteristic variables of influencing factors of adolescent psychological crisis were depression, anxiety, suicidal ideation, self-harming behavior, cognitive flexibility-controllability, cognitive flexibility-selectivity, grit-persistence effort, grit-interest consistency, mother's mood and father's mood(model prediction accuracy was 0.023-0.163).Conclusions:The occurrence of adolescent psychological crisis is closely related to symptom factors, protective factors and parental emotions, and has the significance of predicting across time.The machine learning random forest algorithm can effectively identify psychological crisis individuals and identify sensitive crisis individual characteristics.

Autologous ozonized blood transfusion(AOBT) is a therapy of re-transfusion of 100-200 mL of autologous blood after shaking and agitation with appropriate amount of oxygen-ozone in vitro. The oxidation of blood through the strong oxidation of ozone can enhance the non-specific immune response of the body, regulate the internal environment and promote health. This therapy has been increasingly applied in clinical practice, while no unified standard for the operation process in terms of ozone concentration, treatment frequency and treatment course had been established. This operation process of AOBT is primarily explored in order to standardize the operation process and ensure its safety and efficacy.

Objective:To investigate the status quo of psychological characteristics of mindfulness, family concern and rehabilitation compliance of patients undergoing hip arthroplasty and to explore the internal relationships between psychological characteristics of mindfulness, family concern and rehabilitation compliance of patients undergoing hip arthroplasty in order to clarify the mediating effect of psychological characteristics of mindfulness.Methods:Using the convenient sampling method, a total of 101 patients who underwent hip arthroplasty in Department of Orthopedics in Peking University Shenzhen Hospital from July 2017 to June 2018 were selected as research objects. Five Facet Mindfulness Questionnaire (FFMQ) , Family Adaptability, Partnership, Growth, Affection, and Resolve (Family APGAR) Index and Rehabilitation Compliance Scale were used to conduct questionnaire surveys. The Pearson correlation analysis were used to analyze the correlations between rehabilitation compliance, family concern and psychological characteristics of mindfulness. Then a hypothetical model was established to analyze the mediating effect of psychological characteristics of mindfulness between family concern and rehabilitation compliance.Results:Finally, 90 valid questionnaires were collected. The total scores of FFMQ, Family APGAR Index and Rehabilitation Compliance Scale were respectively (115.01±8.99) , (7.27±0.84) and (5.27±0.92) . The psychological characteristics of mindfulness, family concern and rehabilitation compliance of patients with hip replacement were positively correlated ( r=0.562, 0.491; P<0.01) . The constructed mediation model showed that family concern had a positive predictive effect on rehabilitation compliance ( P<0.05) , psychological characteristics of mindfulness had a positive predictive effect on rehabilitation compliance ( P<0.05) , and psychological characteristics of mindfulness played a mediating role between family concern and rehabilitation compliance of patients with hip replacement. Conclusions:In this study, family concern, psychological characteristics of mindfulness and rehabilitation compliance of patients with hip replacement are all at a moderate level. Psychological characteristics of mindfulness of patients, family concern and postoperative rehabilitation compliance are positively correlated, and psychological characteristics of mindfulness has a mediating role between family concern and rehabilitation compliance. Medical staff can carry out mindfulness psychological interventions for patients with hip replacement to improve family concern and promote rehabilitation compliance of patients.

Objective: To explore the chain mediating effect of cognitive flexibility and depressive cognition between mindfulness and suicide risk in undergraduates. Methods: Suicidal Behaviors Questionnaire-revised (SBQ-R), mindful attention awareness scale (MAAS), cognitive flexibility inventory (CFI) and depressive cognition scale (DCS) were used to investigate 2 627 freshmen from a medical university in Guangdong Province. Results: The scores of suicide risk, mindfulness, cognitive flexibility and depressive cognition were (M(Q_R)): 4.00(2.00), 67.00(15.00), 78.00(13.00), 5.00(7.00), respectively.The results of correlation analysis showed that suicide risk was positively correlated with depressive cognition (r=0.280, P<0.01), and negatively correlated with the level of mindfulness and cognitive flexibility (r=-0.253, r=-0.196, P<0.01). Mindfulness was positively correlated with cognitive flexibility (r=0.539, P<0.01), negatively correlated with depressive cognition (r=-0.518, P<0.01). Cognitive flexibility was negatively correlated with depressive cognition (r=-0.584, P<0.01). Mediation modeling analysis showed that mindfulness had a significant direct effect on suicide risk.The direct effect value was -0.101, accounting for 34.9% of the total effect.The total indirect effect of mindfulness on suicide risk was -0.188, accounting for 65.1% of the total effect.The mediating effect of cognitive flexibility as mediator between mindfulness and suicide risk was -0.063, accounting for 21.8% of the total effect.The mediating effect of depressive cognition as mediator between mindfulness and suicide risk was -0.054, accounting for 18.7% of the total effect.The chain mediating effect of cognitive flexibility and depressive cognition was -0.071, accounting for 24.6% of the total effect. Conclusion Mindfulness can influence suicide risk, not only through the direct path, but also through the indirect path of cognitive flexibility and depressive cognition, as well as the chain mediating path between these two variables.

Objectives:To design a self-control training program based on the recent findings of self-control and self-regulation after taking full consideration of the unique characteristics of depression disorder,with an emphasis on behavioral activation and reinforcement.Methods:Totally 46 students who were diagnosed with major depression were randomly assigned to one of the two groups:Group 1 (n =23),and Group 2 (n =23).Participants in the Group 1 received 24-week self-control training program,as compared to Group 2 who received only baseline and post-24-week-intervention measurements,the measurements included Self-control Scale (SCS) and Beck Depression Inventory (BDI-Ⅱ).The self-control training included eight-week training modules and 16-week consolidation module.Results:In Group 1,the SCS scores were higher in post-intervention than in baseline measurement [(38.0 ± 6.3) vs.(34.7 ± 8.2),P ＜ 0.01],and the BDI-Ⅱ scores were lower in post-intervention than in baseline measurement [(19.0 ± 6.1) vs.(21.8 ± 4.8),P＜0.01] in Group 1.Whereas in Group 2,there were no significant differences between baseline and post-24-week-intervention measurements of SCS and BDI-Ⅱ scores (Ps ＞0.05).Conclusion:The study provides new evidence for the self-regulation model of depression.Self-control training could be an effective intervention strategy for the treatment of depression.

Objective To explore the relationships among negative life events,meaning in life and suicidal risk of college students.Methods A total of 897 students from southern medical university were surveyed by adolescent life events scale (ALES),suicidal behaviors questionnaire-revised (SBQ-R) and meaningful life measure-Chinese revised (MLM-CR).Results The scores of negative life events,meaning in life and suicidal risk were 1.03±0.88,124.32±20.35 and 4.17± 1.66,respectively.There were 64 (7.1％) college students with high risk of suicide.The overall stress score was positively correlated with total suicidal risk score (r=0.134,P＜0.01).Total suicidal risk score was negatively correlated with total score of meaning in life(r=-0.340,P＜0.01).Moderating effects of meaning in life between negative life events and suicidal risk were significant (P＜0.01).Meaning in life fully mediated the effects of negative life events on suicidal risk (P＜0.01),which accounted for 59.6％ of the total effects.Conclusion Meaning in life as a mediator and moderator between negative life events and suicidal risk.Meaning in life might play protective role in reducing the suicidal risk.

Objective To explore the role of mindfullness in the negative life events,depression,and poor sleep quality.Methods Using five facet mindfullness questionnaire(FFMQ),adolescents self-rating life events checklist (ASLEC),self-rating depression scale (SDS) and Pittsburgh sleep quality index (PSQI) to investigate 2 792 freshmen in a medical university in Guangzhou.Results The FFMQ score (126.02±12.14) was negatively correlated with ASLEC score(23.93±19.81),SDS score(35.89±7.31) and PSQI score (3.45±2.13) (r=-0.17,r=-0.44,r=-0.26,P＜0.01).The boys in the aspects of " mindfullnessinaction" scored significantly higher than that of girls (21.20 ± 3.36,20.52±2.88,P＜0.01).The girls scored significantly higher than boys in the PSQI,SDS (3.58±2.15,3.21 ±2.08,P＜0.05;36.22±7.26,35.27±7.35,P＜0.01).Mindfullness and sleep quality showed a chain-mediated effect between negative life events and depression,and the model fitting was good (RMSEA =0.048,CFI =0.962,TLI =0.943).The total mediating effect size was 61.41％.The mediating path through mindfullness,with the effect size of 16.71％,and the chain-mediating effect was 8.94％.Conclusion The higher the level of mindfullness,the lower the individual's depression score and the better the quality of sleep.Mindfullness and the sleep quality play a role of chain-mediating effect between negative life events and depression.

Objective To explore the impact of short-term meditation on ego-depletion in college students.Methods Sixty college students without any meditation and mental calculation experience were recruited voluntarily,and were allocated randomly and equally into three groups: the control group,the rest group,and the meditation group(n=20 in each group).Participants completed the positive affect and negative affect scale and the first handgrip test.A difficult mental calculation task was used to induce ego depletion.After that,the control group performed the second handgrip test immediately,and the rest group had a 5-min break,while the meditation group had a 5-min meditation practice following a meditation audio.Participants then reported the task difficulty and the impulse to write down intermediate answers during the mental calculation task.They also finished the positive and negative affect scale again.The task difficulty and impulse scores,the number of response items and correct items,the change of the handgrip time and the mood between pretest and posttest were compared among three groups.Results There were no differences in the task difficulty score,the impulse score,the number of response items and correct items among the three groups (all P>0.05).The handgrip time was shorter in posttest ((71.91±24.58) s) than in pretest ((91.39±37.63) s) in the control group (P<0.05).The handgrip time was also shorter in posttest ((81.75±25.77) s) than in pretest ((97.88±33.77) s) in the rest group (P<0.05).However,the difference between the handgrip time in posttest ((82.21±34.63) s) and in pretest ((83.11±42.45) s) was not significant in the meditation group (P>0.05).There were no differences in the change of positive and negative affect between pretest and posttest (all P>0.05).Conclusions hort-term meditation buffers ego depletion in college students,which cannot be attributed to affect.

Objective:To explore whether implicit priming of self-awareness can prevent self-control depletion.Methods:Totally 60 college students volunteers were recruited,and were allocated pseudo-randomly and equally into the control group,the non-self-awareness priming group,and the self-awareness priming group,20 volunteers in each group.The scrambled sentence task was applied in implicit priming,the mental calculation task was used to induce self-control depletion indexed by task difficulty,the impulse to write down the intermediate answers,the number of response items and correct items,the handgrip test was used to measure self-control performance,and the Positive Affect and Negative Affect Scale (PANAS) was used to measure affect.The self-control depletion,the handgrip time and the PANAS scores were compared among three groups.Results:There was no significant difference in task difficulty score,impulse score,the number of response items and correct items among the three groups (Ps ＞0.05).The group differences of the change of positive and negative affect before and after depletion were also not significant (Ps ＞0.05).After controlling the effect of the first handgrip time before depletion,the difference of the handgrip time after depletion between the control group and the non-self-awareness priming group was not significant (P ＞ 0.05).However,the handgrip time in the controI group and in the non-self-awareness group were both shorter than that in the self-awareness priming group [(69.2 ± 3.6) s,(71.1 ± 3.6) s vs.(81.9 ± 3.6) s,Ps ＜0.05].Conclusions:It suggests that implicit priming of self-awareness might hold promise in preventing self-control depletion.

Objective To explore the relationship among clinicians' work pressure,perceived social support and compassion fatigue,and to provide a new prospective for the localization studying of intervention and treatment to compassion fatigue.Methods Data of scale for occupational stressors on clinician,perceived social support scale and professional quality of life scale were collected from a sample of 533 clinicians and analyzed with structural equation modeling to study the relationship among clinicians' work pressure,perceived social support and compassion fatigue.Results (1)Work pressure(2.40±0.45),burnout (2.14±0.54) and secondary traumatic stress(1.93±0.60) scores of the clinicians with high perceived social support were significantly lower than that of the clinicians with low perceived social support (2.78±3.67,2.73± 0.59,2.32±0.71;t=7.68,-9.44,8.77,5.07;P＜0.01).Compassion satisfaction scores (4.15±0.63) of the clinicians with high perceived social support were significantly higher than that of the clinicians with low perceived social support (3.40±0.71,t =-9.44,P＜0.01).(2) According to relevant results,work pressure was significantly negative correlation with both perceived social support (r=-0.34,P＜0.01) and compassion satisfaction (r=-0.44,P＜0.01),and significantly positive correlation with both burnout (r=0.69,P＜0.01) and secondary traumatic stress(r=0.53,P＜0.01);while perceived social support was significantly positive correlation with compassion satisfaction (r=0.42,P＜0.01),and significantly negative correlation with burnout (r=-0.40,P＜0.01) and secondary traumatic stress(r=-0.26,P＜0.01).(3) According to the results of structural equation modeling,perceived social support played a partly mediating role in the effect of work pressure toward compassion satisfaction and fatigue with the intermediary effect of 55.4％ and 12.5％.Conclusion Perceived social support plays a mediation role between work pressure and compassion fatigue for clinicians,and better social support of the clinician is beneficial to clinicians mental health level.