Objective:To evaluate the application of three‐dimensional(3D) rotational digital subtraction angiography(DSA) and three‐dimensional reconstruction technique in the interventional treatment of visceral artery aneurysm .Methods:A total of 25 patients with visceral artery aneurysm ,who underwent 3D rotational DSA and reconstruction before the interventional embolization treatment in the Department of Interventional Radiology ,Zhongshan Hospital ,Fudan University during Jan 2007 and Aug 2015 ,were selected .3D rotational DSA and reconstruction was performed by using Siemens Artis DTA or Philips Allura F20 DSA equipment ,and the results were compared with that of conventional 2D DSA .Results:There were 8 hepatic artery aneurysms ,10 splenic artery aneurysms ,3 renal artery aneurysms ,3 gastroduodenal artery aneurysms ,and 1 inferior pancreaticoduodenal artery aneurysm among the 25 patients .The 3D rotational DSA procedures were successful in all patients , and the success rate was 100% .Anatomical morphology including the diameter ,neck and cavity of aneurysm was exhaustively demonstrated .A total of 30 aneurysms were diagnosed by 3D rotational DSA among the 25 patients .Among the 30 aneuryms , only 27 aneurysms were confirmed by conventional 2D DSA ,and the aneurysm necks of 15 aneurysms were not exhaustively demonstrated due to the anatomical overlapping of the large aneurysm cavity , or the vessel tortuosity . Conclusions: As compared to the conventional 2D DSA ,the 3D rotational DSA and reconstruction can demonstrate anatomical information of visceral artery aneurysms more precisely , especially the aneurysm neck , so as to provide more precise images for the interventional diagnosis and treatment .

Objective: To study the clinicopathological characteristics of lung salivary gland-type tumors (SGT), and to compare with the corresponding primary SGT in salivary glands. Methods: Twenty-three cases of lung SGT were retrieved from the files of Peking University First Hospital from January 2004 to September 2018. The morphology, immunophenotype, genotype and outcome of these cases were analyzed. Results: The 23 patients included 13 males and 10 females, with age range of 13-79 years (median 54 years). There were 11 cases of adenoid cystic carcinoma, 10 cases of mucoepidermoid carcinoma (MEC), one case each of clear cell carcinoma and myoepithelioma. The morphology and immunophenotype of lung SGT were very similar to their counterparts in salivary gland. MYB rearrangement was detected in one of 11 adenoid cystic carcinomas. MAML2 rearrangement was detected in all the MECs. EWSR1 rearrangement was detected in the one case of clear cell carcinoma. Of patients with adenoid cystic carcinoma, the survival time was more than 60 months (three cases), 52 months (one case), and 12-36 months (three cases). There was no recurrence and death in seven cases of MEC with follow-up results. One case of clear cell carcinoma recurred after 52 months of follow-up. Conclusions Although the SGT of lung and their counterparts in salivary gland are very similar in their morphology, immunophenotype, genotype and prognosis, there are also some differences between each other. MYB rearrangement can be detected in most adenoid cystic carcinomas of salivary gland, but rarely in lung adenoid cystic carcinoma. The prognosis of patients with lung MEC is better than that of patients with salivary gland MEC, while the prognosis of patients with lung adenoid cystic carcinoma is worse than that of patients with salivary gland adenoid cystic carcinoma.

Carcinogenesis ; Cell Transformation, Neoplastic ; Hepatoblastoma ; Humans ; Liver ; Liver Neoplasms ; Organoids ; YAP-Signaling Proteins