1.Development of an Animal Model for Coronectomy
Hyunna AHN ; Jisun HUH ; Seoyeon JUNG ; Wonse PARK
Journal of Korean Dental Science 2024;17(4):187-200
Purpose:
This study aimed to develop an animal model suitable for coronectomy research. Materials and Methods: Eighteen Sprague-Dawley rats were divided into six groups: incisor control (InC), incisor flap (InF), incisor non-flap (InNF), molar control (MC), molar flap (MF), and molar non-flap (MNF). Coronectomy was not performed in the control groups (InC and MC). In the incisor (In) groups, coronectomy was performed on the mandibular incisors, with flap elevation in the InF group and without flap elevation in the InNF group. In the molar (M) groups, coronectomy was performed on the maxillary first molar, with flap elevation in the MF group and without flap elevation in the MNF group. The incisor groups were sacrificed on day 7, and the molar groups on days 7 and 14. Clinical healing, tooth movement, and histological and immunohistochemical analyses were performed.
Results:
InF and InNF groups showed tooth eruption similar to or the same as that before coronectomy, whereas the MF and MNF groups’ roots moved slowly. In InF and InNF groups, the pulp at the maturation zone was mineralized, but apical pulp vitality was maintained. MF and MNF groups showed bacterial infection and inflammation on day 7, with mineralization on day 14; however, apical pulp vitality was maintained. The MF group showed varied healing patterns, whereas the MNF group had consistent results across individuals.
Conclusion
Both incisors and molars are meaningful models for coronectomy. However, for consistent experimental results, coronectomy without flap elevation on the maxillary first molar is recommended.
2.Development of an Animal Model for Coronectomy
Hyunna AHN ; Jisun HUH ; Seoyeon JUNG ; Wonse PARK
Journal of Korean Dental Science 2024;17(4):187-200
Purpose:
This study aimed to develop an animal model suitable for coronectomy research. Materials and Methods: Eighteen Sprague-Dawley rats were divided into six groups: incisor control (InC), incisor flap (InF), incisor non-flap (InNF), molar control (MC), molar flap (MF), and molar non-flap (MNF). Coronectomy was not performed in the control groups (InC and MC). In the incisor (In) groups, coronectomy was performed on the mandibular incisors, with flap elevation in the InF group and without flap elevation in the InNF group. In the molar (M) groups, coronectomy was performed on the maxillary first molar, with flap elevation in the MF group and without flap elevation in the MNF group. The incisor groups were sacrificed on day 7, and the molar groups on days 7 and 14. Clinical healing, tooth movement, and histological and immunohistochemical analyses were performed.
Results:
InF and InNF groups showed tooth eruption similar to or the same as that before coronectomy, whereas the MF and MNF groups’ roots moved slowly. In InF and InNF groups, the pulp at the maturation zone was mineralized, but apical pulp vitality was maintained. MF and MNF groups showed bacterial infection and inflammation on day 7, with mineralization on day 14; however, apical pulp vitality was maintained. The MF group showed varied healing patterns, whereas the MNF group had consistent results across individuals.
Conclusion
Both incisors and molars are meaningful models for coronectomy. However, for consistent experimental results, coronectomy without flap elevation on the maxillary first molar is recommended.
3.Development of an Animal Model for Coronectomy
Hyunna AHN ; Jisun HUH ; Seoyeon JUNG ; Wonse PARK
Journal of Korean Dental Science 2024;17(4):187-200
Purpose:
This study aimed to develop an animal model suitable for coronectomy research. Materials and Methods: Eighteen Sprague-Dawley rats were divided into six groups: incisor control (InC), incisor flap (InF), incisor non-flap (InNF), molar control (MC), molar flap (MF), and molar non-flap (MNF). Coronectomy was not performed in the control groups (InC and MC). In the incisor (In) groups, coronectomy was performed on the mandibular incisors, with flap elevation in the InF group and without flap elevation in the InNF group. In the molar (M) groups, coronectomy was performed on the maxillary first molar, with flap elevation in the MF group and without flap elevation in the MNF group. The incisor groups were sacrificed on day 7, and the molar groups on days 7 and 14. Clinical healing, tooth movement, and histological and immunohistochemical analyses were performed.
Results:
InF and InNF groups showed tooth eruption similar to or the same as that before coronectomy, whereas the MF and MNF groups’ roots moved slowly. In InF and InNF groups, the pulp at the maturation zone was mineralized, but apical pulp vitality was maintained. MF and MNF groups showed bacterial infection and inflammation on day 7, with mineralization on day 14; however, apical pulp vitality was maintained. The MF group showed varied healing patterns, whereas the MNF group had consistent results across individuals.
Conclusion
Both incisors and molars are meaningful models for coronectomy. However, for consistent experimental results, coronectomy without flap elevation on the maxillary first molar is recommended.
4.Development of an Animal Model for Coronectomy
Hyunna AHN ; Jisun HUH ; Seoyeon JUNG ; Wonse PARK
Journal of Korean Dental Science 2024;17(4):187-200
Purpose:
This study aimed to develop an animal model suitable for coronectomy research. Materials and Methods: Eighteen Sprague-Dawley rats were divided into six groups: incisor control (InC), incisor flap (InF), incisor non-flap (InNF), molar control (MC), molar flap (MF), and molar non-flap (MNF). Coronectomy was not performed in the control groups (InC and MC). In the incisor (In) groups, coronectomy was performed on the mandibular incisors, with flap elevation in the InF group and without flap elevation in the InNF group. In the molar (M) groups, coronectomy was performed on the maxillary first molar, with flap elevation in the MF group and without flap elevation in the MNF group. The incisor groups were sacrificed on day 7, and the molar groups on days 7 and 14. Clinical healing, tooth movement, and histological and immunohistochemical analyses were performed.
Results:
InF and InNF groups showed tooth eruption similar to or the same as that before coronectomy, whereas the MF and MNF groups’ roots moved slowly. In InF and InNF groups, the pulp at the maturation zone was mineralized, but apical pulp vitality was maintained. MF and MNF groups showed bacterial infection and inflammation on day 7, with mineralization on day 14; however, apical pulp vitality was maintained. The MF group showed varied healing patterns, whereas the MNF group had consistent results across individuals.
Conclusion
Both incisors and molars are meaningful models for coronectomy. However, for consistent experimental results, coronectomy without flap elevation on the maxillary first molar is recommended.
5.Distribution of medical status and medications in elderly patients treated with dental implant surgery covered by national healthcare insurance in Korea.
Kyungjin LEE ; Chugeum DAM ; Jisun HUH ; Kyeong Mee PARK ; Seo Yul KIM ; Wonse PARK
Journal of Dental Anesthesia and Pain Medicine 2017;17(2):113-119
BACKGROUND: The purpose of this study was to investigate the distribution of systemic diseases and medications in patients older than 65 years of age who visited the hospital for implant treatment, as well as to investigate basic information about surgical complications that may occur after insured implant treatment. METHODS: A total of 126 patients over 65 years of age were treated for implant surgery from October 1, 2013 to October 30, 2016. Electronic chart review was conducted to obtain medical records, which included sex, age, systemic diseases, medication(s) being taken, and control of the medications. Five patients were excluded due to lack of medical records giving information about systemic disease. RESULTS: Of the 126 patients, 112 (88.9%) were taking medication due to systemic disease and 9 patients (7.1%) were not. The sex distribution was 71 women and 55 men and the highest proportion of patients were between 65 and 69 years old. The most common diseases were, from most to least frequent, hypertension, cardiovascular disease, diabetes, and osteoporosis. The drug groups that can cause major complications after dental treatment were classified as hemorrhagic, osteoporotic, and immunosuppressive agents, and were taken by 45 (35.7%), 22 (17.5%) and 4 (3.2%) patients, respectively. CONCLUSION: Given that 88.9% of the elderly patients who were eligible for insurance implant treatment had systemic disease, it is necessary to carefully evaluate patients' medical histories and their general conditions in order to prevent emergencies during implant surgery.
Aged*
;
Cardiovascular Diseases
;
Delivery of Health Care*
;
Dental Implants*
;
Emergencies
;
Female
;
Humans
;
Hypertension
;
Immunosuppressive Agents
;
Insurance*
;
Korea*
;
Male
;
Medical History Taking
;
Medical Records
;
National Health Programs
;
Osteoporosis
;
Postoperative Complications
;
Sex Distribution
6.Successful Peritoneal Dialysis in an Extremely Preterm Infant.
Jisun HUH ; Jihye HWANG ; Eun Hee LEE ; Yoon Jung BOO ; Byung Min CHOI ; Young Sook HONG
Neonatal Medicine 2016;23(3):158-162
Peritoneal dialysis can be considered renal supportive therapy, even in an extremely low birth weight infant with acute kidney injury not responding to general supportive measures. Although there have been several reports of successful peritoneal dialysis in extremely low birth weight infants, general practice guidelines and commercially available optimal peritoneal dialysis catheters have not been introduced. We report a successful case of peritoneal dialysis in an extremely low birth weight infant born at 25 weeks gestational age, with birth weight 790 g, with uncontrollable metabolic acidosis, hyperkalemia, progressive azotemia and continued anuria.
Acidosis
;
Acute Kidney Injury
;
Anuria
;
Azotemia
;
Birth Weight
;
Catheters
;
General Practice
;
Gestational Age
;
Humans
;
Hyperkalemia
;
Infant
;
Infant, Extremely Low Birth Weight
;
Infant, Extremely Premature*
;
Infant, Low Birth Weight
;
Infant, Newborn
;
Peritoneal Dialysis*
7.The influence of mandibular skeletal characteristics on inferior alveolar nerve block anesthesia.
Tae Min YOU ; Kee Deog KIM ; Jisun HUH ; Eun Jung WOO ; Wonse PARK
Journal of Dental Anesthesia and Pain Medicine 2015;15(3):113-119
BACKGROUND: The inferior alveolar nerve block (IANB) is the most common anesthetic techniques in dentistry; however, its success rate is low. The purpose of this study was to determine the correlation between IANB failure and mandibular skeletal characteristics METHODS: In total, 693 cases of lower third molar extraction (n = 575 patients) were examined in this study. The ratio of the condylar and coronoid distances from the mandibular foramen (condyle-coronoid ratio [CC ratio]) was calculated, and the mandibular skeleton was then classified as normal, retrognathic, or prognathic. The correlation between IANB failure and sex, treatment side, and the CC ratio was assessed. RESULTS: The IANB failure rates for normal, retrognathic, and prognathic mandibles were 7.3%, 14.5%, and 9.5%, respectively, and the failure rate was highest among those with a CC ratio < 0.8 (severe retrognathic mandible). The failure rate was significantly higher in the retrognathic group than in normal group (P = 0.019), and there was no statistically significant difference between the other two groups. CONCLUSIONS: IANB failure could be attributable, in part, to the skeletal characteristics of the mandible. In addition, the failure rate was found to be significantly higher in the retrognathic group.
Anesthesia*
;
Dentistry
;
Mandible
;
Mandibular Nerve*
;
Molar, Third
;
Skeleton
8.The influence of mandibular skeletal characteristics on inferior alveolar nerve block anesthesia.
Tae Min YOU ; Kee Deog KIM ; Jisun HUH ; Eun Jung WOO ; Wonse PARK
Journal of Dental Anesthesia and Pain Medicine 2015;15(3):113-119
BACKGROUND: The inferior alveolar nerve block (IANB) is the most common anesthetic techniques in dentistry; however, its success rate is low. The purpose of this study was to determine the correlation between IANB failure and mandibular skeletal characteristics METHODS: In total, 693 cases of lower third molar extraction (n = 575 patients) were examined in this study. The ratio of the condylar and coronoid distances from the mandibular foramen (condyle-coronoid ratio [CC ratio]) was calculated, and the mandibular skeleton was then classified as normal, retrognathic, or prognathic. The correlation between IANB failure and sex, treatment side, and the CC ratio was assessed. RESULTS: The IANB failure rates for normal, retrognathic, and prognathic mandibles were 7.3%, 14.5%, and 9.5%, respectively, and the failure rate was highest among those with a CC ratio < 0.8 (severe retrognathic mandible). The failure rate was significantly higher in the retrognathic group than in normal group (P = 0.019), and there was no statistically significant difference between the other two groups. CONCLUSIONS: IANB failure could be attributable, in part, to the skeletal characteristics of the mandible. In addition, the failure rate was found to be significantly higher in the retrognathic group.
Anesthesia*
;
Dentistry
;
Mandible
;
Mandibular Nerve*
;
Molar, Third
;
Skeleton
9.Characteristics of patients who visit the dental emergency room in a dental college hospital
Chihun KIM ; Eunhye CHOI ; Kyeong Mee PARK ; Eun Jung KWAK ; Jisun HUH ; Wonse PARK
Journal of Dental Anesthesia and Pain Medicine 2019;19(1):21-27
BACKGROUND: Emergencies in dentistry can be classified as medical and dental. Medical emergencies occur mainly during dental treatment in patients with a systemic disease. Dental emergency departments are largely divided into dental emergency rooms located in dental college hospitals and medical emergency rooms located in medical institutions. This study aimed to analyze the characteristics of and provide help to dental emergency patients in a dental hospital. METHODS: Overall, 1806 patients admitted to a dental emergency room at Yonsei University Dental Hospital for 1 year were included. The data collection period was from October 1, 2014 to September 30, 2015. An investigator reviewed medical records from the electronic medical record (EMR) system and radiographs. RESULTS: The patients were 1,070 men and 736 women. The sex ratio was 1.45:1. The commonest age group was of 0–9 years, including 451 (25.0%) patients, followed by 20–29 years, including 353 (19.5%) patients, and 30–39 years, including 277 (15.3%) patients. Of the 108 patients transferred to the Severance emergency department, 81 had trauma, 19 were in pain, 4 were bleeding, and 4 had other complaints. Among chief complaints, 1,079 patients (60.3%) had trauma, 564 (31.5%) had pain, and 75 (4.2%) had bleeding. Twenty-three cases (1.3%) were caused by temporomandibular disorder (TMD). CONCLUSION: Dentists should be able to adequately assess patients in a dental emergency room and treat trauma, pain, and bleeding.
Data Collection
;
Dentistry
;
Dentists
;
Electronic Health Records
;
Emergencies
;
Emergency Service, Hospital
;
Female
;
Hemorrhage
;
Humans
;
Male
;
Medical Records
;
Research Personnel
;
Retrospective Studies
;
Sex Ratio
;
Temporomandibular Joint Disorders
10.Foreign body aspiration and ingestion in dental clinic: a seven-year retrospective study
Jisun HUH ; Namkwon LEE ; Ki-Yeol KIM ; Seoyeon JUNG ; Jungyul CHA ; Kee-Deog KIM ; Wonse PARK
Journal of Dental Anesthesia and Pain Medicine 2022;22(3):187-195
Background:
This retrospective study investigated the incidence rate of accidental foreign body aspiration and ingestion according to patient sex, age, and dental department. This study aimed to verify whether the incidence rate is higher in geriatric than in younger patients and whether it is different among dental departments.
Methods:
Accidental foreign body aspiration and ingestion cases were collected from electronic health records and the safety report system of Yonsei University Dental Hospital from January 2011 to December 2017. The collected data included patients’ age, sex, medical conditions, treatment procedures, and foreign objects that were accidentally aspirated or ingested. The incidence rate was calculated as the number of accidental foreign body aspirations and ingestions relative to the total number of patient visits. Differences depending on the patients’ sex, age, and dental department were statistically identified.
Results:
There were 2 aspiration and 37 ingestion cases during the 7-year analysis period. The male to female incidence ratio was 2.8:1. The incidence rate increased with age and increased rapidly among those aged 80 years or older. Seven of the 37 patients with accidental foreign body ingestion had intellectual disability, Lou Gehrig’s disease, dystonia, or oral and maxillofacial cancer. The incidence rate was highest in the Predoctoral Student Clinic and the Department of Prosthodontics. The most frequently swallowed objects were fixed dental prostheses and dental implant components.
Conclusion
The incidence rate of accidental foreign body aspiration and ingestion differed according to patient sex, age, and dental department. Dental practitioners must identify high-risk patients and apply various methods to prevent accidental foreign body aspiration and ingestion in dental clinics. Inexperienced practitioners should be particularly careful.