Objective:To explore the time course of memory recovery during post-traumatic amnesia after brain injury.Methods: A patient (WGS, aged 34) with lesions in the left temporal lobe was compared with four matched control subjects on various cognitive tests. These tests included Galveston Orientation and Amnesia test, Wechsler Memory Scale-Revised Test, Semantic Memory, and Remote Memory Test. WGS was tested at 20th days and 33rd days after the brain injury. Results: During the period of post-traumatic amnesia, marked recovery was observed for orientation, semantic memory and remote memory (especially the recent and the earlier items). While the recovery of learning for new knowledge was slow, learning curve of association of unrelated items was flat.Conclusion: The differential time courses for recovery of cognitive functions should be well considered in rehabilitative training after traumatic brain injury.

Objective This study investigates the protective effect of bicyclol on liver function in patients after liver resection.Methods One hundred and twenty patients undergoing liver resection with Pringle's maneuver were randomly divided into groups A,B,and C,and given bicyclol (50 mg),diammonium glycyrrhizinate (150 mg),and silybum marianum (77 mg),respectively.The medication was orally given preoperatively for 5 days and postoperatively for days 3 to 7.The fasting serum ALT,AST,TB,ALP,and PAB levels were determined before operation and on days 1,3,5,and 7 after operation.Results ALT levels in the A group were significantly lower than those in the B and C group on post operative days 1,3,5,and 7 (P＜0.01).On postoperative day 7,the ratio of serum ALT returned to normal was significantly higher than the B and C group ratios (P＜0.05).Conclusion Therefore,oral bicyclol given before and after liver resection can significantly inhibit the rapid increase and promote the normalization of serum ALT levels.

Establishment of the “Happy Reading Club” was to create a personal reading space for undergraduates. The reading situation of undergraduates was analyzed with the creation processes of “Happy Reading Club” summa-rized.The reading popularizing activities were described, including questionnaire investigation of reading, sign of DIY “tree”, and recommendation of classic booklist, with the existing problems pointed out.

OBJECTIVE: To investigate the efficacy of revision endoscopic sinus surgery and combined therapy on recurrent sinusitis and polyps. METHOD: Revision endoscopic sinus surgery was performed in 72 patients, of which endoscopic nasal lateral wall dissection was used in 3 cases, the endoscopic frontal sinus surgery (Draf I-II) was used in 16 cases, and all patients received combined therapy including peri-operation conservative management and nasal endoscopy examination during the follow-up period. RESULT: All patients were followed up for more than one year. Of 72 patients, 52 patients were successfully cured, 10 patients showed improvement, but there was no change in other 13 patients. The total efficacy rate was 91.67% (66/72). No serious complication occurred. CONCLUSION The treatment efficacy can be greatly improved by enough preoperative preparation, fine operation, combined pre-operation conservative therapy and postoperative follow-up.
Adult ; Aged ; Endoscopy ; Female ; Humans ; Male ; Middle Aged ; Nasal Polyps ; prevention & control ; surgery ; Recurrence ; Sinusitis ; prevention & control ; surgery ; Young Adult

Objective To evaluate the clinical application of early total care (ETC) for polytrauma patients combined with thoracolumbar fractures.Methods A retrospective case control study was conducted to analyze the clinical data of 137 polytrauma patients combined with thoracolumbar fractures admitted to the First Affiliated Hospital of Soochow University and the Third People's Hospital of Zhang,jiagang from January 2012 to October 2015.There were 90 males and 47 females,aged 26-69 years,with an average age of 48.2 years.The patients were divided into ETC group (n =59) and TMC group (n =78).In the ETC group,physicians from different departments evaluated the patients and developed individualized therapeutic regimens to allow the patients to undergo surgery at early stage after injury.The TMC group preferentially stabilized the patient's condition or transferred the patients to specialist treatment,and then the surgery was performed electively after the condition of the patient was stable.The ISS of the ETC group was (22.15 ± 9.28)points,and that of the TMC group was (23.37 ± 10.74) points.All patients underwent conventional posterior pedicle screw internal fixation.For patients with burst fracture and nerve injury,posterior spinal canal decompression was performed.The thoracolumbar injury classification and severity score (TLICS),spinal load sharing classification (LSC),preoperative and postoperative Glasgow coma score (GCS),Frankel classification,hospitalization time and postoperative complications were compared between the two groups.Results The TLICS scores of ETC group were significantly lower than those of TMC group (P ＜ 0.05) while the LSC scores showed no significant differences between the two groups (P ＞ 0.05).ETC group had shorter hospitalization time [(11.8 ± 3.7)days ∶ (17.5 ±4.5)days] and lower pressure ulcer incidence [(5％ ∶ 21％)] than the TMC group (P ＜ 0.05 or 0.01),but the former had significantly higher wound infection rate [(17％ ∶ 15％)] (P ＜ 0.05).There was no significant difference in pulmonary infection and deep venous thrombosis incidence between the two groups (P ＞ 0.05).No significant differences were found in the preoperative GCS scores between the two group (P ＞ 0.05) while the postoperative GCS scores of TMC group were higher than those of ETC group (P ＜ 0.01).Postoperative GCS scores in both groups were significantly higher than their preoperative GCS (P ＜ 0.05).The results of postoperative Frankel classification in the ETC group were as follows:Grade A in one patient,Grade B in one,Grade C in three,Grade D in four and Grade E in two patients,with an improvement rate of 82％.The results of postoperative Frankel classification in the TMC group were as follows:Grade A in three patients,Grade B in three,Grade C in three,Grade D in four and Grade E in four,with an improvement rate of 65％.Conclusions For polytrauma patients combined with thoracolumbar fractures,ETC can shorten hospitalization time,reduce the pressure ulcer incidence,and better facilitate the recovery of nerve function,yet with higher wound infection risk compared with TMC.TMC was preferred subjectively for patients with unstable thoracolumbar fractures and high TLICS.

ObjectiveTo analyze the epidemiological characteristics of hepatitis B virus （HBV） infection among blood donors in Hainan Province. MethodsHBV screening was conducted on 6 851 samples from voluntary blood donors in Hainan Province from January 2020 to January 2023. The samples were grouped according to donation frequency， method， age， gender， occupation， and education level， and risk factors related to HBV infection and genotypes were analyzed. ResultsThe HBV infection rate among first-time blood donors （3.59%） was higher than that among repeat donors （0.16%）. Among first-time blood donors， the HBV infection rate in males （2.22%） was higher than in females （1.66%）， and the infection rate increased with age （all P<0.05）. Blood donors who were teachers （1.18%）， militaries （1.01%）， civil servants （1.27%）， and medical staffs （0.85%） had lower HBV infection rate， while workers （6.05%）， farmers （6.15%）， and freelancers （7.61%）， and service industry workers （8.77%） had higher HBV infection rate. The infection rate decreased with higher education levels （P<0.05）. Multivariate logistic regression analysis showed that multiple blood donations （OR=0.623， 95%CI： 0.337‒0.945）， history of intravenous transfusions （OR=1.694，95%CI： 1.517‒1.946）， and family history of HBV infection （OR=1.768， 95%CI： 1.265‒1.934） were independent risk factors for HBV infection （all P<0.05）. Significant differences were observed among different HBV genotypes in terms of HBeAg positivity rate， HBeAb positivity rate， incidence of post hepatitis B cirrhosis， as well as levels of ALT， AST， and HBV-DNA （all P<0.05）. The results of multivariate logistic regression analysis showed that age， HBeAg， HBV-DNA， and clinical type were risk factors for HBV genotype distribution （P<0.05）. ConclusionHainan Province is a low-prevalence area for HBV infection， but the latent risk for HBV infection still exists. Therefore， it is important to thoroughly understand the basic information and HBV infection genotypes of blood donors， so as to select healthy blood donors and reduce the discovery and transmission of HBV-positive cases among blood donors.