MicroRNA(miRNA)constitute a large family of small,approximately 21 to 23 nucleotide-long,non-coding RNA that is a key post-transcriptional regulators of gene expression.By base pairing to mRNA,miRNA mediate translational repression or miRNA degradation.The recent study find that miRNA play an important role in carcinogenesis.Here is a reviews of the research advances of miRNA and ovarian cancer.

In order to know the general analysis ability of nursing students,the author chose 120 nursing students in grade 2002 and grade 2003 to carry out a pathological test with two kinds of test methods,and compared and analyzed their test performances statistically.The results show that there is obvious difference between the two kinds of test methods.The author is of the opinion that the nursing students are lack of general analysis ability in pathological study and it is necessary to improve the teaching method and test method.

Objective: To explore psoriasis vulgaris efficacy of the narrow band UVB therapy combined with compound glycyrrhizin. Methods: The study made it clear diagnosis for patients admitted to our hospital 45 patients with psoriasis vulgaris were randomly divided into experimental group with 25 cases(narrow band UVB therapy combined with compound glycyrrhizin) and control group with 20 cases(only narrow-band UVB irradiation), in order to compare and analyze the treatment effect, the incidence of adverse reactions and symptoms before and after treatment PASI score recorded. Results: The difference was not statistically significant about PASI score of patients in the experimental group and the control group before treatment(t=0.153, P>0.05). But the difference of PASI score was statistically significant between two groups of patients after treatment(t=4.675, P<0.05). The effective rate of treatment in patients of the experimental group was 92%and 75%in the control group. The adverse symptoms in the experimental group and control group were 20% and 60% respectively. The differences were statistically significant (x2=47.908, P<0.05). Conclusion: Narrow band UVB combined with compound glycyrrhizin treatment of psoriasis with respect to only a narrow band ultraviolet therapy have significant therapeutic effect, and it can effectively reduce the incidence of adverse symptoms. It is worth popularizing in clinical.

Objective To study the evaluation of ultrasonic gastrography examination(UGE) in general survy.Methods Collected and analyzed the cases of physical examination in outpatient service ,from Jan,2007 to Mar,2007,in which all the patients who stated having upper bellyache underwent UGE. Compared the results of UGE with results of gastroscope examination to find out the accuracy of UGE.Results The image manifestations have a certain degree regularities .The percentage of accurate ultrasonic diagnoses is 89%.Conclusions UGE is an effective method to diagnose gastric diseases.

Objective:To explore the relationship between polymorphism of endothelial nitric oxide synthase(eNOS)gene G894T and coronary heart disease(CAD)in Han Nationlity.Methods:Polymerase chain reaction-restricted fragments length polymorphism(PCR-RFLP)was used to determine the genotype of the eNOS gene G894T in 103 patients with CAD and 104 controls.Results:There was significant difference in frequencies of allele in G894T polymorphism of eNOS gene between CAD and control groups(P=0.029),but there was no significant difference in genotype distribution between two groups.Logistic regression analysis revealed that hypertension,diabete mellitus and smoking history were independent risk factors for the incidence of CAD,but T allele was not.Conclusion:The frequency of eNOS gene G894T mutation in the CAD group is higher than that in the control group and T allele may be related to with the development of CAD.

Objective:To observe the effect of periodontal initial therapy on the serum level of lipid in the patients with both periodontitis and hyperlipidemia.Methods:Twenty patients with both hyperlipidemia and moderate to severe chronic periodontitis were enrolled in this study.Periodontal parameters [plaque index(PLI),bleeding on probing(BOP),bleeding index(BI),probing depth(PD) and attachment level(AL)] were evaluated prior to and 3 months after periodontal initial therapy.Simultaneously,the patients' serum levels of total cholesterol,triglyceride,high-lipoprotein cholesterol,low-lipoprotein cholesterol were also measured.Results:(1) Three months after periodontal therapy,the periodontal infection and inflammation in patients reduced comparing with baseline.The PD,PLI,BI,and BOP decreased significantly(the PD,PLI,BI,and BOP reduced from 3.98?0.12 to 2.39?0.13,1.23?0.10 to 0.84?0.08,2.63?0.14 to 1.48?0.08 and 94.26?1.84 to 33.57?2.06,respectively;P

0.05).Conclusion Oral misoprostol alone is as effective as oxytocin alone for the prevention of postpartum hemorrhage.It is less effective than oral misoprostol plus oxytocin.Misoprostol is applicable for high risk pregnancy with some vascular changes.

This paper summarizes the results the treatment of 100 cases with infectious allergic arthritis with alpha-Polyantigen and its etiologic analysis. After treatment in 90.48% of patients the joints swelling and pain subsided in 1-10 days; ESR, alpha-2, gama-globulin, C-3 decreased ( p

Objective To evaluate the effects of developing professional value of nursing students based on Chinese medicine culture.Methods 69 nursing students in the second year were divided into the intervention group(n=34) and the control group (n=35).The students in the intervention group received a 3-month education project based on Chinese medicine culture,while the control group received only routine education plan.The effect of the intervention was evaluated by nursing professional values-R (NPVS-R) at the end of the intervention.Results The scores of NPVS-R including total scores and the scores of the two dimensions of caregiving and behavioristic in the intervention group significantly increased compared with those in the control group.Conclusions The intervention of developing professional value of nursing students based on Chinese medicine culture can improve the level of professional value.

An extract(Polysaccharide)from Zhu-Ling(Polyporus umbellatus)and hydro- cortisone acetate were injected into mice for seven days in the experiment.Peritoneal macrophages were taken out for cytochemical analysis.The results were quantified with MPV-2 microspectro-photometer.It was found that the activity of AePase, ATPase and ANAE and the content of polysaccharide were reduced after injection with hydrocortisone acetate;that the activity of AcPase,ATPase and ANAE and the content of polysaccharide were enhanced after injection with the extract from Zhu-Ling;and that the hydrocortisone acetate and the extract from Zhu-Ling were injected into mice at the same time,the activity of enzymes and the content of polysaccharide were similar to the control group.