Objective: To investigate the effects of Pingzhi Jianxin tea(平脂健心茶) on treating hyperl ipaemia and its mechanisms.Methods:One hundred and twenty cases with hyperlipaemia were randomly divided into trea tme nt group and control group, the treatment group was treated with Pingzhi Jianxin tea and the control group was t reated with gingko nut leaf tablet.The curative effects between two groups were compared.Meanwhile, experimental study on animal model of hyperlipaemia was conducted.Results:The total effective rates in depressing blood lipids and viscosity in treatment group was 92.5% and in control group was 72.5%.The total effective rates in electrocardiogram improvements were 65.5% and 56.3% respectively.The difference between two groups was significant(P<0.01 and P<0.05)． In experimental study the blood lipid of hyperlipaemia rats was reduced after taking Pingzhi Jianxin tea and this action in treatment group was superior to that in control group (P<0.01). Conclusions:The curative effects of Pingzhi Jianxin tea on treating hyperlipaemia and improving myocardial ischemia are confirmed and if used for a long time there is not harmful effect.

Epilepsy is a brain dysfunction syndrome resulted from many causes,which is closely related to age,especially occuring in the immature brain.Long-term,repeated seizures can lead to immature brain tissue damage,and increase susceptibility of immature brain to epileptic brain damage.Not only does substantia nigra network have the effect of delicate anticonvulsion,but it is also vulnerable to epilepticseizures.Protecting the immature brain substantia nigra pars can prevent or reduce the risk of seizures,epilepsy has an important role in brain injury recovery.Giving children the brain protective drugs aimed directly at substantia nigra pars is a viable and effective method to treat epileptic brain injury.

Objective To observe clinical effects of treming duodenal ulcer with rebeprazole combined with ulcer powder.Methods 78 cases patients with duodenal ulcer were randomly divided into a control group and a treatment group.The control group was treated wlth omeprazole,and the treatment group was treated with rebeprazole combined with ulcer powder.Thetherapeutic effects and adverse reaction were observed in both groups.Ayear's follow-up was performed after the treatment to observe ulcer recurrence rate of the two groups.Results The therapeutic effects of the treatment group were significantly better than the control group,and adverse reaction and ulcer recurrence rate of the treatment group were markedly lower than the control group.Conclusion The therapy of rebeprazole combined with ulcer powder has better effect in treating patients with duodenal ulcer than omeprazole.

Obiective To observe clinical effect of treating patients with chronic gastritis with Banxiaxiexin decoction combined with western medicine. Methods 65 patients with chronic gastritis were randomly recurited into a control group and a treatment group. The control group was treated with western medicine, and the treatment group was treated with Banxiaxiexin decoction combined with western medicine. The therapeutic effects and adverse reaction were observed in both groups. Results The therapeutic effect in the treatment group were significantly better than that of the control group, with P<0.05. While the adverse reaction of the treatment group was markedly lower than that of the control group. Conclusion Banxiaxiexin decoction combined with western medicine therapy has better effects in treating patients with chronic gastritis than exclusive western medicine.

Objective:To compare the measures of activated blood platelets in different disease conditions and the effects of aspirin on blood clots.Methods:The expression of activated platelet CK62p and CD63 and its changing after taking aspirin in 126 tumor patients and 60 non-tumor patients was detected with flow cytometry.Result:The expression of activated platelet CK62p and CD63 in tumor patients was significantly higher than that in non-tumor patients(P

To study the effect of iron deficiency (ID)on crythrocyte membrane proteins, an investigation of the activity and site of Na+-K+-ATPase in crythrocyte membrane of rats with iron deficient anemia (IDA) was conducted. It was found that changes of the enzyme activity had various ciiaracteristics as ID course went on, and there was no difference in the numbers of 3H-ouabain binding sites (R0) between IDA rats and controls. In contrast to the controls, Na+-K+- ATPase activity of IDA rats showed no relation with R0, suggesting a primary association of the abnormalized activity of the enzyme with its molecular state in ID erythrocyte membrane which could be affected by the surroundings of cell metabolism and spatial structure.

OBJECTIVE:To study the pharmacological action of Shaducao oral succus in mice.METHODS:Pole-climbing test,charcoal clearance test,ear-swelling test,ink-propelling test were conducted respectively to observe the antifatigue action of Shaducao oral succus,and its effect on nonspecific immunity,anti-inflammatory and anti-diarrhea effects on mice. RESULTS: Shaducao oral succus markedly prolonged the duration of mice in climbing pole,and it also showed remarkable antifatigue effect. High dose of Shaducao oral succus significantly enhanced mice's charcoal clearance coefficient and clearance capacity index and enhanced mice's immune function.At high,middle and low doses,Shaducao oral succus markedly ameliorated dimethyl benzene-induced otitis,significantly lowered the ink-propelling speed,and satisfactorily relieved diarrhea. CONCLUSION: Shaducao oral succus was proved to be of certain antifatigue,anti-inflammatory and anti-diarrhea effects meanwhile it could enhance the nonspecific immunity of mice.

Objective To explore clinical effect of integrative medical therapy on infantile bronchiolitis. Methods 96 infants with bronchiolitis were randomly divided into a treatment group and a control group. The treatment group was treated with integrated traditional Chinese and western medicine, and the control group was treated with western medicine exclusively. Results The disappearance time for symptoms and signs in the treatment group was shorter than that of the control group. The hospitalized time (or time for observation of outpatient infusion) of the treatment group was also shorter than that of the control group (P＜0.05). The cure rate was 78.0% and the total effective rate was 96.0%% in the treatment group. However, the cure rate was 52.2% and the total effective rate was 69.6% in the control group, which had a significant difference in the two groups (P＜0.05). Conclusion Integrated traditional Chinese and western medicine can obviously shorten course of disease and hospitalized time, and also improve the curative effect of infantile bronchiolitis.

Objective To use computer and network technologies for Adverse Drug Reaction(ADR) monitoring.Methods Design adverse drug reaction clinical briefing system software, use the advance of the briefing system in monitoring the adverse drug reactions with fast and convenient and high efficiency.Results The reported rate of adverse drug reactions increased significantly.Conclusion Hospitals strengthen ADR monitoring will help improve quality of medical care and safety of rational drug use.

OBJECTIVE:To observe the efficacy and safety of Clotrimazole vaginal tablet in the treatment of pregnancy with vulvovaginal candidiasis. METHODS:106 pregnant patients with vulvovaginal candidiasis were randomly divided into observation group (56 cases) and control group (50 cases). Observation group was given one tablet Clotrimazole vaginal tablet,washed the genital area before treatment to keep clean and one Clotrimazole vaginal tablet was sent to intravaginal 5-6 cm,once every 2 day. Control group was given Lactobacillus vaginal capsule,once a day,washed the genital area before treatment and one Lactobacillus vaginal capsule was sent to intravaginal 5-6 cm. The treatment course for both groups was 8 d. No sexual activities during treatment and no other drugs. Clinical efficacy,clearance rate of candidiasis,pregnancy and incidence of adverse reactions in 2 groups were observed. RESULTS:The total effective rate and clearance rate of candidiasis in observation group were significantly higher than control group,carrier rate was significantly lower than control group,the differences were statistically significant (P<0.05). And there were no significant differences in the pregnancy and incidence of adverse reactions between 2 groups (P>0.05). CONCLU-SIONS:Clotrimazole vaginal tablet shows significant efficacy in the treatment of pregnancy with vulvovaginal candidiasis and can clear candidiasis,with good safety.