1.Advancement of Reovirus-based therapy for cancer
Jinye HUANG ; Lijun MAO ; Jiacun CHEN
Journal of International Oncology 2010;37(7):514-517
Reovirus,a kind of oncolytic viruses, is seldom pathogenic, but is selectively able to replicate in cancer cells through activation of Ras signaling. Pre-clinical studies have demonstrated that treatment with reovirus is associated with significant anticancer activity across a range of tumor types. Further clinical evaluation of reovirus therapy has shown that it is well tolerated when administered locally or systemically. Encouraging anticancer efficacy has been observed with single-agent treatment and in combination with chemotherapy and radiotherapy. High safety and promising efficacy of reovirus has raised hopes that it will become a new anticancqt agent.
2.Multiple measures to improve the pre-examination quality of laboratory medicine: practice and experience
Nengliang OUYANG ; Weijia WANG ; Fuda HUANG ; Shaosheng SU ; Haili LAN ; Juan WANG ; Kang CHEN ; Jinye XIE
Chinese Journal of Hospital Administration 2020;36(6):500-503
The hospital improved its pre-examination quality of laboratory medicine by means of setting up pre-examination quality management committee, full-course supervision of pre-examination process, and clarified responsibility system. Informationization means play multiple roles for the pre-examination quality, including full-course management, early warning and interception of unqualified sample. The coordinated application of multi-departments, multi-links and multi-measures can improve the pre-examination quality of laboratory medicine and ensure the quality of test results and the medical safety of patients.